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Aug 7

Dr. David Katz, Preventive Medicine: Ending a decade of diet lies – New Haven Register

Published 7:08pm, Sunday, August 6, 2017

Ancel Keys, arguably the most influential nutrition scientist of the past half-century, died in 2004 at the age of 100. Keys invented the K ration, named for him, that provided our deployed military with portable and complete nutrition. He was among the first, if not the first, to hypothesize that heart disease was not an inevitable consequence of aging but likely related to diet and lifestyle.

Obvious as that now seems, someone had to be the first to consider it and that someone was Ancel Keys. He developed and directed the Seven Countries Study, a colossal undertaking that tested the above hypothesis, concluding that variation in dietary sources of saturated fat notably meat and dairy contributed importantly to cardiovascular risk.

Throughout most of his life, Keys was celebrated as a public health hero. He graced the cover of TIME Magazine as such in 1961. In the years leading up to his death, however, and in the decade since, much of the public commentary about Keys, his lifes work, his seminal Seven Countries Study, and his integrity has been derogatory. There are five apparent reasons for this.

The first is perhaps best described as Newtonian: for every action, an equal and opposite reaction. Maybe we simply cant resist the inclination, whenever someone settles securely on a pedestal weve placed under them, to shift our efforts to knocking them down.

The second might best be described as Aesopian, as in the Aesops Fable that says: we are all judged by the company we keep. The latter years of Keys life, and those since his death, were concurrent with misguided forays into low-fat dietary boondoggles, and somebody had to be blamed for Snackwells. In many quarters, that somebody wound up being Ancel Keys, for having pointed out the harms of dietary fat albeit only certain dietary fat in the first place.

The third reason is that everyone seems to love a good conspiracy theory. So, there were careers to launch and books to sell, as there are today, by telling us all that everything authorities had advised was wrong, that the real truth was being concealed, distorted or suppressed. As one of the worlds preeminent epidemiologists, Keys was among such authorities, and thus an obvious target of conspiracy theory, revisionist history and alternative facts.

The fourth reason was the advent of the internet.

Once upon a time, you needed actually to know something to broadcast expertise, because an editorial filter stood between you and the public at large. There were ways around this, of course, such as the reliance on celebrity as an alternative to content knowledge as a basis for selling books, lotions, potions or programs. But even so, the means of disseminating messages favored those with some claim to genuine merit.

Now, anyone with internet access can broadcast opinion, masquerading as expert opinion, into the echo chambers of cyberspace, where those who own the same opinion already will amplify it. So, for instance, those totally devoted to eating or selling meat, butter and cheese are also apt to eat up, and regurgitate, any allegations against those pointing out the related liabilities.

The fifth is the most obvious: along with not wearing plaid, dead men dont fight back very effectively, either. Keys has mostly been turned into a scapegoat since dying. By way of reminder, he lived to 100 and applied what he thought he knew about diet and lifestyle to himself. That alone would make him a candidate for both celebrity and expert status today. One imagines the book: Diet of the Century.

The popular allegations against Keys are: (1) he cherry picked countries to enroll in his study to align with the beliefs he already held; (2) he fudged or selectively presented data to make a case aligned with the beliefs he favored; (3) he either failed to study sugar or misrepresented findings about it; and (4) he advocated for a now generally discredited low-fat dietary pattern.

The True Health Initiative, a 501c3 nonprofit organization I founded to identify and disseminate the fundamental truths about lifestyle and the health of people and planet alike, based on the weight of evidence and the global consensus of experts, commissioned a White Paper to determine the veracity of these claims. The paper, with its extensive and fully transparent bibliography of primary source material, was just released, and is accessible to all. The basic conclusion is that all popular disparagements of Keys and his research are demonstrably false.

Lies, repeated often enough, can smother the truth. After a decade of lies about Ancel Keys and the Seven Countries Study, its time for the truth to break free, and strike back clad in plaid or otherwise.

Dr. David L. Katz;www.davidkatzmd.com; founder, True Health Initiative

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Dr. David Katz, Preventive Medicine: Ending a decade of diet lies - New Haven Register


Aug 6

Diet and age-related memory loss [excerpt] – OUPblog (blog)

Age-related memory loss is to be expected. But can it be mitigated?

There are many different steps we can take to help maintain and even improve our memories as we age. One of these steps is to make a few simple dietary changes. The following shortened excerpt from The Seven Steps to Managing Your Memory lists dietary basics that can benefit memory.

Omega- 3 fatty acids (often shortened to omega- 3s) are important for a number of functions in the body, including the proper function of our brain cells and reduction of inflammation. Although our bodies make many of the fats we need, we cannot make omega- 3s, and so we need to get them from food. There are three main types of omega- 3s and, because you may have heard claims about each of them, well mention them briefly (despite their long names). Docosahexaenoic acid (DHA) has been associated with brain health and cognitive function, control of inflammation, as well as heart health. Eicosapentaenoic acid (EPA) has been associated with heart health and control of inflammation. Alpha- linoleic acid (ALA) is a source of energy and also a building block for both DHA and EPA. Scientific studies examining the benefits of omega- 3s have been mixed, but some research suggests that they may benefit brain health.

Our recommendation is to make sure your balanced diet does include some omega- 3 fatty acids. The most common sources of omega- 3s include fish (particularly fatty fishes such as salmon and tuna), walnuts, green leafy vegetables (such as kale), flaxseeds, and flaxseed oil. Other foods are now being fortified with omega- 3s. You may find eggs, milk, juice, and yogurt fortified with omega- 3s in your local grocery store.

Vitamin D is essential for brain health. In one study, individuals with low levels of vitamin D were about twice as likely to develop dementia and Alzheimers disease compared to those whose levels were normal. Most older adults dont have enough vitamin D. Although you can make vitamin D through your skin, to do so you would need to spend a lot of time outside without sunblock, which you shouldnt do. We recommend a daily intake of 2,000 IU of vitamin D3, usually from supplement pills. You can also get vitamin D from fatty fish (such as tuna and salmon), portobello mushrooms grown under an ultraviolet light, and foods fortified with vitamin D including milk, cereal, and orange juice. Be sure to read the label to see if the product you buy is fortified or not. Lastly, there are some important interactions between vitamin D and some prescription medications, so you should speak with your doctor prior to taking vitamin D supplements.

Antioxidants can defend the body against the harmful effects of free radicals chemicals that can damage cells, including brain cells. Some of the most common antioxidants are vitamins A, C, and E, along with flavonoids and beta- carotene. Most studies looking at the impact of antioxidant supplementation through pills have offered little support that taking these antioxidant pills improves thinking and memory. In fact, taking high doses of antioxidants in pill form can be problematic, with some studies showing that high intake of antioxidants is associated with an increased risk of cancer and death and can negatively interact with certain medications. Thus, although some clinicians would recommend taking antioxidant supplements, such as vitamin E, we do not.

The evidence suggests that eating antioxidant- rich foods, such as fruits and vegetables, can reduce the risk of chronic health conditions such as heart disease and stroke, which, in turn, can improve the health of the brain. Many researchers now believe that it is the types and variety of antioxidant foods that people are consuming that matters most, rather than simply the total amount of antioxidants consumed. We therefore recommend eating fruits and vegetables as part of a balanced diet.

One of the most important ideas that has emerged from the scientific literature is that it may not be any one dietary item that makes a difference in the health of our brains. Instead, it is likely that the complex combination of nutrients obtained through a balanced diet is best. The Mediterranean diet is one such balanced diet that has shown promise for brain health. This diet calls for high consumptions of fruit, whole grains (like bulgur, barley, and brown rice), beans, and vegetables at every meal. The diet is low in saturated fats (the bad fats) but encourages the intake of monounsaturated good fats that lower the bad cholesterol. These healthy fats, found in olive oil, avocados, and nuts, should be eaten frequently. Fish is recommended at least twice a week. Low to moderate amounts of dairy products such as yogurt and cheese can be consumed daily or weekly. Red wine is also a staple of the Mediterranean diet. Red meat and sweets (such as candy, cookies, cake, and ice cream) should be consumed sparingly.

One way the Mediterranean diet helps the brain is by reducing risk factors for stroke such as high cholesterol and diabetes. One study showed that brain volumes were larger for those who followed the Mediterranean diet, equivalent to being five years younger! Other studies have shown that people who eat a Mediterranean diet have a lower risk of mild cognitive impairment and Alzheimers disease dementia compared to those who ate a more typical diet. Not all studies support the idea that the Mediterranean diet is good for cognition and reduced risk of memory loss, but many studies do, and none of the studies reported any side effects that would caution against adopting such a diet in an effort to keep the brain healthy. We therefore recommend a Mediterranean- type diet to everyone looking to modify their lifestyle in a way that benefits brain health.

Featured image credit: food-avocado-healthy-fresh by gutolordello. CC0 via Pixabay.

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Diet and age-related memory loss [excerpt] - OUPblog (blog)


Aug 6

Packers players’ diet includes veggies, fruits, carbs, and protein – Fox11online.com

by Brittany Ford, FOX 11 News

A look at one of the items on the menu when Packers players stay at St. Norbert College for training camp. (WLUK/Mike Raasch)

DE PERE (WLUK) -- If you're a Packers player, your diet is just as important as your performance.

During training camp, chefs at St. Norbert make sure the players are served a variety of tasty, and nutritious meals.

In the Michels Ballroom, at St. Norbert College, Packers players eat their meals.

St. Norbert Chef T.W. Stanciu has been cooking at training camp for 13 years.

As the players stay on campus, the university provides both a snack, and dinner.

FOX 11 got a sneak peek at one of the menu items.

T.W. says during the players stay there is usually a rotating menu.

"We'll repeat most of the items, but I'll watch what they eat, if they like it we'll put it on," said T.W. Stanciu.

He says over the years, they have taken a healthier approach to the menu, hints the kale in this burger.

"We like to use buffalo meat, because it's better for the athletes," he said. "Back six year ago, they weren't eating as healthy, we had snacks, candy, malts but we switched that up," he said.

He says the players' diet mostly consist of vegetables, fruits, carbs, and protein.

"You wouldn't think an omelet after 8:30 at night, would be something you want to eat, but they love it," Stanciu said.

As he topped of the burger, and put it out for display.

"This something we'll probably we'll serve for the Green Back Packers during Training Camp," Stanciu said.

He says training camp is a time the college looks forward to each year.

"It's nice to see the progress over the years," he said.

St. Norbert and the Packers have the longest standing relationship between a college and Pro football team. 2017 marks 60 years.

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Packers players' diet includes veggies, fruits, carbs, and protein - Fox11online.com


Aug 6

High Fat Diet Raises Breast Cancer and Mental Illness Risk in Offspring – Care2.com

Few people consider what their mom and dad ate as a factor in their health many years later. But, research shows that what parents eat just prior to conception and, in the case of women, during pregnancy, can affect a childs risk for certain illnesses later in life.

In a study published in the online medical journal BioMed Central, researchers found that both parents diets prior to conception, and a womans pregnancy diet, can affect their childrens risk for breast cancer later in life. In this study researchers assessed the effects of a high fat diet, largely composed of omega 6 fatty acids found in corn oil, which is representative of an average persons high omega 6 fatty acid intake in North America. The researchers found that the parental high fat diet caused genetic damage that predisposed the offspring to breast cancer. While breast cancer primarily affects women, it can also affect men.

But breast cancer is not the only illness linked to a high fat diet. In a new study published in the medical journal Frontiers in Endocrinology, researchers found that a mothers high fat diet during pregnancy can not only affect her childrens risk of obesity, but also brain development and mental health issues like anxiety. In this study, researchers assessed the effects of a high fat diet (35.57 percent of the total caloric intake as fat) for 1.2 to 8.5 years prior to giving birth. However, saturated fat (which is the main type of fat in meat and poultry) made up the largest percentage of the total fat intake. The researchers found that the maternal high fat diet made the offspring significantly more prone to neurodevelopmental disorders like anxiety.

The researchers also found that the high fat diet impaired the development of brain cells containing serotonina brain messenger hormone that is critical to developing brains and helps to regulate depression and anxiety.

As the researchers of the studies indicate and to which I would agree: this is not about blaming our parents, and mothers in particular, for our health problems. Instead, it is about raising public awareness and improving public health policies to ensure the greatest level of health for people throughout their lifetime.

Both saturated fats and a diet high in omega 6 fatty acids have been linked to excessive inflammation in the body. Reduce your intake of meat and commercially-prepared vegetable oils which are largely corn oil, and foods made from these oils, such as packaged, processed and prepared foods.

Instead, choose a largely plant-based diet high in fruits and vegetables with the addition of foods rich in omega 3 fatty acids like flaxseeds and flaxseed oil, walnuts, chia seeds, hemp seeds, spinach, squash and cashews. Check out my blog Top 17 Vegan Sources of Omega 3 Fatty Acids to discover more plant-based sources of brain-boosting omega 3 fatty acids.

Related:The Vitamins that Protect Your DNA against Air PollutionDont Believe in Herbal Medicine? 10 Things to Change Your MindThe 5 Best Herbs to Soothe Your Nerves

Dr. Michelle Schoffro Cook, PhD, DNM is the publisher of the free e-news Worlds Healthiest News, president of PureFood BC, and an international best-selling and 20-time published book author whose works include: Boost Your Brain Power in 60 Seconds: The 4-Week Plan for a Sharper Mind, Better Memory, and Healthier Brain.

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High Fat Diet Raises Breast Cancer and Mental Illness Risk in Offspring - Care2.com


Aug 4

The Mediterranean diet works but not if you’re poor, a study finds – Chicago Tribune

We've long heard that the Mediterranean Diet is how all of us should eat. The diet, inspired by the coastal cuisine of such countries as Greece, Italy and southern France, is characterized by its abundant portions of fruits and vegetables, frequent meals of fish and poultry, use of olive oil and spices for seasoning, and red wine in moderation. Red meat and butter are limited, and grains are mostly whole. The diet has been studied for its effects on heart disease, weight loss, cancer, Parkinson's and Alzheimer's diseases. And it's arguably a more pleasurable way of eating than, say, the strict Paleo and Ketogenic diets, or the faddish but not necessarily effective low-carbohydrate diet.

But it won't work if you're poor.

That's the latest finding from a team of Italian researchers, who studied 18,000 men and women over a four-year period. They found that the Mediterranean Diet reduced the risk of heart disease by 15 percent - but only for people who made more than approximately $46,000 a year. There were no observed cardiovascular benefits for people who made less than that amount.

The study, which was published in the International Journal of Epidemiology, also found that highly educated people - who may be likely to have higher incomes - did better on the diet, in part because they selected a wider variety of vegetables and were more likely to eat whole grains. The more varied a person's diet is, the more types of nutrients they consume. Highly educated participants were also more likely to buy organic food.

The study "found that higher-SES subjects tend to consume more organic vegetables which can contain higher concentrations of antioxidants, lower concentrations of cadmium and a lower incidence of pesticide residues, as compared with conventionally grown foods. We might then speculate that the quality of the bundle of foods that make up the MD actually differs across SES."

So, it doesn't just matter that you adhere to the tenets of the Mediterranean Diet - it matters what kind of foods you pick within its framework, how that food was grown and how you prepare it. The findings will inevitably contribute to the ongoing discussion of food inequality, or how access to healthful food is a tenet of social justice.

We have long known that poorer Americans lack access to nutritious food and full-service grocery stores. They are more likely to rely on processed or fast foods. One recent study found that this nutritional gap is widening. "Price is a major determinant of food choice, and healthful foods generally cost more than unhealthful foods in the United States," that study said. It also found a link between education and healthy eating, suggesting that programs to teach low-socioeconomic status people how to choose and prepare cheap healthy meals - and the benefits they can derive from such choices - are important.

And that's what the Italian research team's takeaway is. "These results support the need to adopt more effective strategies aiming to reduce socioeconomic disparities in health, not only by promoting the adoption of healthy eating patterns but also by facilitating access to foods with higher nutritional values," they wrote.

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The Mediterranean diet works but not if you're poor, a study finds - Chicago Tribune


Aug 4

High-fat diet linked to lung cancer risk – Reuters

(Reuters Health) - People who eat a lot of saturated fat - the bad kind of fat thats abundant in foods like butter and beef - are more likely to develop lung cancer than individuals on low-fat diets, a recent study suggests.

Compared to adults who didnt get a lot of fat in their diets, people who ate the most total fat and saturated fat were 14 percent more likely to get lung malignancies, the study found. For current and former smokers, the added risk of a high fat diet was 15 percent.

While the best way to lower the risk of lung cancer is to not smoke, a healthy diet may also help reduce lung cancer risk, said study co-author Danxia Yu of Vanderbilt University Medical Center in Nashville, Tennessee.

Specifically, our findings suggest that increasing polyunsaturated fat intake while reducing saturated fat intake, especially among smokers and recent quitters, may (help prevent) not only cardiovascular disease but also lung cancer, she said.

The American Heart Association recommends the Dietary Approaches To Stop Hypertension (DASH) diet or a Mediterranean-style diet to help prevent cardiovascular disease. Both diets emphasize cooking with vegetable oils with unsaturated fats, eating nuts, fruits, vegetables, low-fat dairy products, whole grains, fish and poultry, and limiting red meat and added sugars and salt.

Those guidelines are the same for avoiding heart disease, stroke and diabetes, and I would say they are also exactly the same for helping with cancer prevention in general and lung cancer in particular, said Dr. Nathan Berger, a researcher at Case Western Reserve University and University Hospitals Cleveland Medical Center who wasnt involved in the study.

This doesnt mean you need to throw away all the steak and butter in your freezer, but cutting back to once a week would be good for you, Berger said in a phone interview.

For the current study, researchers examined data from 10 previously published studies in the United States, Europe and Asia that looked at how dietary fat intake influences the odds of lung malignancies.

Combined, the smaller studies had more than 1.4 million participants, including 18,822 with cases of lung cancer identified during an average follow-up of more than nine years.

Researchers sorted participants into five categories, from lowest to highest consumption of total and saturated fats. They also sorted participants into five groups ranging from the lowest to highest amounts of dietary unsaturated fats.

Overall, people who ate the most unsaturated fats were 8 percent less likely to develop lung cancer than people who ate the least amounts, researchers report in the Journal of Clinical Oncology.

Substituting five percent of calories from saturated fat with unsaturated fat was associated with a 16 percent lower risk of small cell lung cancer and 17 percent lower odds of another type of lung malignancy known as squamous cell carcinoma.

One limitation of the study is that dietary information was only obtained at one point, the authors note. This makes it impossible to track how changes in eating habits might influence the odds of cancer.

They also didnt account for two other things that may contribute to cancer sugar and trans fats, Glen Lawrence, a biochemistry researcher at Long Island University in Brooklyn, New York, said by email. Previous research has also found that unsaturated oils may increase the risk of certain cancers, added Lawrence, who wasnt involved in the current study.

Its also possible that other bad eating habits, not fat, contribute to the increased risk of lung cancer, said Ursula Schwab of the Institute of Public Health and Clinical Nutrition at the University of Eastern Finland in Kuopio.

We need antioxidants, vitamins and minerals as well as unsaturated fatty acids, Schwab, who wasnt involved in the study, said by email. A typical Western diet has a low content of these essential nutrients and a high content of saturated fat.

SOURCE: bit.ly/2wsZteB Journal of Clinical Oncology, online July 25, 2017.

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High-fat diet linked to lung cancer risk - Reuters


Aug 4

Fisher’s steady diet of play has roots in his diet – Bengals.com

Body by Fisher: Jake Fisher thinks his solid play is tied to his diet.

One of the keys to the return of The Jungle just might be the animal grazing on Jake Fishers menu that has fed his career revival.

Bison. And plenty of it.

Thats been Fishers favorite since he decided to re-invent his body after last season. "Lean, quality," he says. Its also his lunch as gets ready for Thursdays practice, already cooked and delivered by his personal chef.

Bison. Potato. Corn. Theres an avocado on top of the take-home box. A steak waits for after practice. Then therell be a delivery some time Thursday to load him up for next week.

The avocado is for electrolytes. Its a science, man, Fisher says.

You don't have to exactly be a scientist to realize that Fisher, one of those two young tackles taking over for departed left tackle Andrew Whitworth and transitioning right tackle turned right guard Andre Smith, is under enormous pressure. Yet he has quietly emerged during the first week of training camp. If you listen to enough camp scuttlebutt, it tells you Fisher is the most consistent offensive lineman of the first week of work.

As much as hes getting raves for his play, hes raving about his diet that has not only beefed him up to 310 pounds but has purged his psyche. He says he hasnt taken any medications since October in an effort to avoid post-career side effects. He says even his immune system is stronger and he rarely gets sick.

I feel way better. More healthy. Mentally and physically, Fisher says. Guys get soaked up a lot of times in what a coach wants them to be at weight-wise that they sacrifice. I just didnt sacrifice ... Everyone has their own way of doing things. Fine tuning. It takes effort. In my third year I have it down pretty well."

Now ensconced at right tackle after two years of playing everywhere but where they drafted him to play, Fisher has re-made his body. At one point last season as he fought nagging injuries and moved around while Cedric Ogbuehi tried right tackle, Fisher slid to 279 pounds at his lightest. As soon as the season ended with Fisher playing the last three games at right tackle, he recruited a South Florida nutritionist.

Multi positions. Not being consistent. Playing tight end, KOR (kick-off return). All kinds of different things, says Fisher of the reasons for his weight loss. Now that Im at a spot where I earned a spot on the line I can really keep my weight up and really focus on what specific things Im doing.

One of the reasons the Bengals drafted Fisher two years ago is because of how conscientious he is. That was the scouting report on him coming out of Oregon it was obvious when they brought him to Paul Brown Stadium for a pre-draft visit. Now its come to the forefront.

Its hard, but its what I want to do. To be great, Fisher says. Its not what Im eating. Its when Im eating, how Im eating. Portions. Timing. Morning and night. Its really just a matter of realizing that everyones body is different. Its not if its more or less, but its quality. Im not sacrificing quality to eat more quantity. Im eating more often. Never allowing myself to be hungry. Eat more often. Always have your body pumping Insulin.

Fisher says he crushed, weights in the offseason on the road to a happy and healthy 310. But he also says, Its what you eat.

Thursday dinner after practice? A rib-eye steak. Some potatoes. Carrots. A little shake. Then before bed, pasta. And when he gets up, more pasta. The week-long reserve is stashed in a locker room refrigerator.

Keep the Insulin level high throughout the night when I sleep, Fisher says.

But it looks like no one is sleeping on Fisher during this steady diet of solid play.

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Fisher's steady diet of play has roots in his diet - Bengals.com


Aug 4

Trump’s new chief of staff plans to restrict the president’s media diet. Others have tried and failed. – Washington Post

Maybe John F. Kelly can actually do it. If so, he will be the first.

Politico reports that the new White House chief of staff plans to restrict the flow of information to President Trump including news media reports in the hope of keeping the boss on a more even keel. Here's a bit from reporter Josh Dawsey:

When new White House Chief of Staff John F. Kelly huddled with senior staff on his first day at work, he outlined a key problem in President Donald Trumps White House that he planned to fix: bad information getting into the presidents hands.

Kelly told the staff that information needed to flow through him whether on paper or in briefings because the president would make better decisions if given good information.

Kelly's diagnosis makes perfect sense, but others have tried and failed to tame Trump by monitoring his media diet.

President Trump's relationship with television goes back decades and now that he's in the White House, his TV-watching habit is still going strong. (Peter Stevenson/The Washington Post)

If candidate Trump was upset about unfair coverage, it was productive to show him that he was getting fair coverage from outlets that were persuadable, Sam Nunberg, a former campaign adviser, told Politico in February.

Politico's Tara Palmeri wrote at the time that the key to keeping Trumps Twitter habit under control, according to six former campaign officials, is to ensure that his personal media consumption includes a steady stream of praise.

Okay. But the idea that Trump's Twitter habit has ever been under control is laughable. Maybe these campaign officials know something the rest of us don't that Trump's tweets would have been even more inflammatory if not for their interventions.

We'll probably never know about tweets that Trump didn't send. If his staffersmanaged to him out of trouble even a few times, then their efforts were worthwhile. But no one has been able to consistently prevent Trump from stirring up controversy.

Part of the problem is that in a White House composed of competing factions, people invariably try to advance their agendas by presenting Trump with material which may or may not be reliable that promotes their worldviews.

Politico all over this story reported in May on advisers' penchants for strategically feeding dubious information to the president. This was one example, described by reporter Shane Goldmacher:

Current and former Trump officials say Trump can react volcanically to negative press clips, especially those with damaging leaks, becoming engrossed in finding out where they originated.

That is what happened in late February when someone mischievously gave the president a printed copy of an article from GotNews.com, the website of Internet provocateur Charles C. Johnson, which accused deputy chief of staff Katie Walsh of being the source behind a bunch of leaks in the White House.

No matter that Johnson had been permanently banned from Twitter for harassment or that he offered no concrete evidence or that he had lobbed false accusations in the past and recanted them. Trump read the article and began asking staff about Walsh.

Goldmacher added that then-chief of staff Reince Priebus and White House staff secretary Rob Porter have tried to implement a system to manage and document the paperwork Trump receives. How'd that work out?

Kelly is trying to do the same thing, three months later. Perhaps he will prove a more effective manager than Priebus, but Trump is still his impulsive self, and his aides are still vying for influence. Those immutable factors will make Kelly's mission very difficult.

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Trump's new chief of staff plans to restrict the president's media diet. Others have tried and failed. - Washington Post


Aug 3

Protein-rich diet may help soothe inflamed gut – Washington University School of Medicine in St. Louis

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Mice fed tryptophan develop immune cells that foster a tolerant gut

The combination of a bacterium that normally lives in the gut and a protein-rich diet promotes a more tolerant, less inflammatory gut immune system, according to new research at Washington University School of Medicine in St. Louis. The findings, in mice, suggest a way to tilt the gut immune system away from inflammation, potentially spelling relief for people living with inflammatory bowel disease.

Immune cells patrol the gut to ensure that harmful microbes hidden in the food we eat dont sneak into the body. Cells that are capable of triggering inflammation are balanced by cells that promote tolerance, protecting the body without damaging sensitive tissues. When the balance tilts too far toward inflammation, inflammatory bowel disease can result.

Now, researchers at Washington University School of Medicine in St. Louis have found that a kind of tolerance-promoting immune cell appears in mice that carry a specific bacterium in their guts. Further, the bacterium needs tryptophan one of the building blocks of proteins to trigger the cells appearance.

We established a link between one bacterial species Lactobacillus reuteri that is a normal part of the gut microbiome, and the development of a population of cells that promote tolerance, said Marco Colonna, MD, the Robert Rock Belliveau MD Professor of Pathology and the studys senior author. The more tryptophan the mice had in their diet, the more of these immune cells they had.

If such findings hold true for people, it would suggest that the combination of L. reuteri and a tryptophan-rich diet may foster a more tolerant, less inflammatory gut environment, which could mean relief for the million or more Americans living with the abdominal pain and diarrhea of inflammatory bowel disease.

The study is published Aug. 3 in the journal Science.

Postdoctoral researcher Luisa Cervantes-Barragan, PhD, was studying a kind of immune cell that promotes tolerance when she discovered that one group of study mice had such cells, while a second group of study mice that were the same strain of mice but were housed far apart from the first group did not have such cells.

The mice were genetically identical but had been born and raised separately, indicating that an environmental factor influenced whether the immune cells developed.

She suspected the difference had to do with the mices gut microbiomes the community of bacteria, viruses and fungi that normally live within the gastrointestinal tract.

Cervantes-Barragan collaborated with Chyi-Song Hsieh, MD, PhD, the Alan A. and Edith L. Wolff Distinguished Professor of Medicine, to sequence DNA from the intestines of the two groups of mice. They found six bacterial species present in the mice with the immune cells but absent from the mice without them.

With the help of Jeffrey I. Gordon, MD, the Dr. Robert J. Glaser Distinguished University Professor, the researchers turned to mice that had lived under sterile conditions since birth to identify which of the six species was involved in inducing the immune cells. Such mice lack a gut microbiome and do not develop this kind of immune cell. When L. reuteri was introduced to the germ-free mice, the immune cells arose.

To understand how the bacteria affected the immune system, the researchers grew L. reuteri in liquid and then transferred small amounts of the liquid without bacteria to immature immune cells isolated from mice. The immune cells developed into the tolerance-promoting cells. When the active component was purified from the liquid, it turned out to be a byproduct of tryptophan metabolism known as indole-3-lactic acid.

Tryptophan commonly associated with turkey is a normal part of the mouse and the human diet. Protein-rich foods contain appreciable amounts: nuts, eggs, seeds, beans, poultry, yogurt, cheese, even chocolate.

When the researchers doubled the amount of tryptophan in the mices feed, the number of such cells rose by about 50 percent. When tryptophan levels were halved, the number of cells dropped by half.

People have the same tolerance-promoting cells as mice, and most of us shelter L. reuteri in our gastrointestinal tracts. It is not known whether tryptophan byproducts from L. reuteri induce the cells to develop in people as they do in mice, but defects in genes related to tryptophan have been found in people with inflammatory bowel disease.

The development of these cells is probably something we want to encourage since these cells control inflammation on the inner surface of the intestines, Cervantes-Barragan said. Potentially, high levels of tryptophan in the presence of L. reuteri may induce expansion of this population.

Cervantes-Barragan L, Chai JN, Tianero MD, DiLuccia B, Ahern PP, Merriman J, Cortez VS, Caparon MG, Donia MS, Gilfillan S, Cella M, Gordon JI, Hsieh C-S, Colonna M. Lactobacillus reuteri induces gut intraepithelial CD4+CD8 alpha alpha+ T cells. Science. Aug. 3, 2017

This work was supported by the National Institutes of Health (NIH), grant numbers U01 AI095542, DK103039, RO1 DK094995, RO1 CA176695, and DK30292; the Kenneth Rainin Foundation; Burroughs Wellcome Fund; the NIH Directors New Innovator Award, identification number 1DP2AI124441; a Sir Henry Wellcome Postdoctoral Fellowship, number 096100; the Swiss National Science Foundation, grant number PBSKP3-134332; and the Swiss Foundation for Medical-Biological Grants, grant number PASMP3-145751.

Washington University School of Medicines 2,100 employed and volunteer faculty physicians also are the medical staff of Barnes-Jewish and St. Louis Childrens hospitals. The School of Medicine is one of the leading medical research, teaching and patient-care institutions in the nation, currently ranked seventh in the nation by U.S. News & World Report. Through its affiliations with Barnes-Jewish and St. Louis Childrens hospitals, the School of Medicine is linked to BJC HealthCare.

More:
Protein-rich diet may help soothe inflamed gut - Washington University School of Medicine in St. Louis


Aug 3

Diet Doc Offers Customized Weight Loss Solutions Amid Mediterranean Diet Doubts – GlobeNewswire (press release)

Sioux Falls, SD, Aug. 03, 2017 (GLOBE NEWSWIRE) --

The Mediterranean diet or lifestyle remains perhaps the best choice for heart-health and overall well-being. However, recent studies are pointing to the fact that even a well-intentioned dieter who eats Mediterranean most of the time may not derive the same benefits as someone in a higher income bracket. Marialaura Bonaccio, the lead author of a study published in the International Journal of Epidemiology told CNN, We found heart advantages were limited to high socioeconomic status groups, even if groups showed the same adherence to the Mediterranean diet. Those with higher incomes have greater access to higher quality foods, and those with more education may use better cooking methods that preserve the nutritional value of the meals being consumed.

Those in the Mediterranean region and surrounding areas, generally benefit from reduced instances of cardiovascular disease, inflammation, cancer, diabetes, obesity and a host of other conditions. The Mediterranean Diet, consists of a primarily plant-based diet, also encourages the consumption of lean meats and heart-healthy oils. Given the results of this latest study, however; Diet Doc offers an even better recommendation: customized diet planning. For those looking to not only lose weight but improve their overall health, Diet Docs team of certified doctors and nutritionists create individualized diet guidelines based on each persons unique body composition and health needs. Diet Doc provides a comprehensive program that also addresses poor eating habits and stress-based eating behaviors with unlimited support from an expert team of professionals.

To get started, new Diet Doc patients can call or easily and effortlessly visit https://www.dietdoc.com to complete an initial comprehensive, yet simple, health questionnaire and schedule an immediate personal, no-cost consultation. Diet Doc Physicians all received specialized training in nutritional science and fast weight loss. Diet Doc reviews each patients health history to create a personalized diet plan geared for fast weight loss, or that addresses life-long issues causing weight loss to slow down or stop. Nutritionists work personally with each patient and use their own algorithm to craft meal and snack plans that are compatible with each patients age, gender, activity level, food preferences, nutritional needs and medical conditions. They combine these state of the art diet plans with pure, prescription diet products that enable their patients to resist the temptation to reach for sugary snacks, eliminate fatigue and curb the appetite. Over 97% of Diet Doc patients report incredible weight loss results with the majority losing 20 or more pounds per month.

At Diet Doc, all patients gain unlimited access to the best minds in the business. Their staff of doctors, nurses, nutritionists and coaches are available 6 days per week to answer questions, offer suggestions, address concerns and lend their professional guidance and support. Because of this, more and more people are turning to Diet Doc for their weight management needs. Diet plans are tailored to be specific to the needs of those of any age, gender, shape or size and for those who are struggling to lose that final 10-20 pounds to those who must lose 100 pounds or more. Call today to request a private, confidential, no-cost online consultation.

About the Company:

Diet Doc Weight Loss is the nation's leader in medical, weight loss offering a full line of prescription medication, doctor, nurse and nutritional coaching support. For over a decade, Diet Doc has produced a sophisticated, doctor designed weight loss program that addresses each individual specific health need to promote fast, safe and long term weight loss.

Diet Doc Contact Information:

Providing care across the USA

Headquarters:

San Diego, CA

(800) 581-5038

Info@DietDoc.com

Homepage

Twitter: https://twitter.com/DietDocMedical

Facebook: https://www.facebook.com/DietDocMedicalWeightLoss/

Linkedin: https://www.Linkedin.com/company/diet-doc-weight-loss?trk=biz-brand-tree-co-logo

Attachments:

A photo accompanying this announcement is available at http://www.globenewswire.com/NewsRoom/AttachmentNg/67db52ea-09c2-421c-ab97-297793f55df1

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Diet Doc Offers Customized Weight Loss Solutions Amid Mediterranean Diet Doubts - GlobeNewswire (press release)



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