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Things are rapidly changing around us, but the good thing is that as we do our part to flatten the curve, we can eventually see an end in sight. That means we can pack up our work from home essentials and plan to get back outside. Get out of that pair of sweatpants and into a pair of jeans you love while Everlane is marking all of their denim down to $50.

Personally, I swear by the Cheeky Straight Jeans in the Ankle length (thanks to being 51). Theyre comfortable all day, with just enough stretch, and are the perfect length for a small cuff at the ankle. They come in a handful of colors that will go with everything in your closet. Or go for the Performance Jean for men, which says everything about it in its name. The four-way stretch organic denim gives you movability and because its part of Everlanes Uniform line, theres a 365-day guarantee if they rip, fade, or shrink.

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Scouted selects products independently and prices reflect what was available at the time of publish. Sign up for our newsletter for more recommendations and deals. Curious about a specific product or brand? Let us know! If you buy something from our posts, we may earn a small commission.

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You're Gonna Leave the House Eventually. Grab Everlane Denim While It's on Sale - The Daily Beast

Good nutrition somehow has a direct impact on ones overall health and quality of well-being. When you follow a healthy diet that consists of fruits, vegetables, and whole grains, you arent just satisfying your hunger, but youre nourishing your body too. Nutrition serves as an essential aspect of a healthy lifestyle, the importance of which just cannot be undermined. But are we even familiar that the benefits of good nutrition go beyond weight? The Bridge caught up with Arunava Bhattacharyya, a certified personal trainer, and nutritionist to discuss how good nutrition helps boost ones health and how to go about it.

Source: Instagram / Arunava Bhattacharyya

Proper nutrition means to be benefitted with all kinds of nutrients, vitamins, and minerals that a human body needs to work its best. Usually, the source of daily calories consumed becomes just as important as the number of calories we consume. Nutrition trainers often stress upon limiting the consumption of empty calories, which comes with food that provides little or no nutritional value at all.

There is a common belief that in order to become fit, you should hit the gym or maybe enroll yourself in Zumba classes or be involved with any physical activity. Even when doctors come across an overweight person, they usually advise for a morning walk or jog. But I have been stressing upon how important nutrition is to our health. There is a lot beyond the kind of physical activities we do daily, says Arunava.

Also read: Could proper nutrition be the Achilles heel to coronavirus?

However, there is a piece of much differing information out there when it comes to nutrition. As a consequence, it can be sometimes difficult to figure out the healthiest ways to eat. But having said that, one might wonder what to expect to familiarise with specific requirements and limitations while consuming a proper diet.

Source: Deccan Chronicle

Ghee always had its own benefits, but in between, it had a nasty reputation of being high in saturated fats. Ghee, butter, and coconut oil are rich in Medium Chain Triglycerides (MCT). MCT is helpful in boosting energy and increasing endurance, besides it plays an important role in improving weight management, he explains.

But then, how does one build an ideal nutritional plan? Experts suggest it is all about balanced proportions of a nutrient-rich diet from various food groups, and adhering to several healthy eating habits. Besides, vitamin and mineral use has skyrocketed over the past decade as the nation has experienced a massive health and wellness boom.

In general, it is believed by health experts that our diets should be our main source for vitamins, minerals, and antioxidants. Should health supplements replace a well-balanced diet, one may argue. Human bodies, as Arunava admits, are naturally designed to absorb and make use of nutrients as they occur in foods.

Source: Instagram / Arunava Bhattacharyya

The deadly coronavirus presents many uncertainties, and none of us can completely eliminate our risk of being infected. But what we can definitely do is eat as healthily as possible. If infected, our immune system is responsible for fighting it, because research shows improving nutrition helps support optimal immune function. Micro-nutrients essential to fight infection include vitamins A, B, C, D, and E, and the minerals iron, selenium, and zinc.

The fear of Coronavirus is more because of the way it has been spreading. As a matter of fact, there is not enough research to suggest where this virus is originating from. One of my friends called up and said that his father is prescribing homeopathic medicines to help people cure them of coronavirus. To me, 99% of it is misinformation that has been floating around, Arunava suggests.

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Know what this nutrition expert believes is best to fight coronavirus - The Bridge

With all the concern about the coronavirus, many want to optimize their immune systems to keep themselves healthy and less at risk. There are three primary ways we can vitalize ourselves nutrition, rest and relationship to stress.

Nutrition is a critical determinant of immune response like anything else, immunity functions better when its well-nourished and has the building blocks it need to do its job.

Protein malnutrition is associated with significant impairment of immunity, especially for healing and recovery. Eat a variety of protein foods, including seafood, lean meat, poultry, eggs, beans and peas, raw nuts and seeds or other plant-based proteins.

Vitamin A helps regulate the immune system and protect against infections by keeping skin and tissues in the mouth, stomach, intestines and respiratory system healthy. Get this immune-boosting vitamin from foods such as sweet potatoes, carrots, broccoli, spinach, red bell peppers, apricots and eggs.

Vitamin C helps protect you from infection by stimulating the formation of antibodies and boosting immunity. Include more sources of this healthy vitamin by choosing citrus fruits such as oranges, grapefruit and tangerines, or red bell pepper, papaya, strawberries or tomato juice. If you buy the effervescent packets of C, make sure you get the ones with no added sugar most of those packets have a teaspoon or more of sugar each.

Vitamin E works as an antioxidant, neutralizes free radicals and may improve immune function. Include vitamin E in your diet with fortified cereals, sunflower seeds, almonds, vegetable oils, hazelnuts and peanut butter.

Zinc helps the immune system work properly and may help wounds heal. Zinc can be found in lean meat, poultry, seafood, milk, whole grain products, beans, seeds and nuts.

Other nutrients, including vitamin B6, folate, selenium, iron, as well as prebiotics and probiotics, also influence immune response, even when the deficiency is mild.

Fats or lipids are substances that exert a profound effect in the modulation of the immune system. The fatty acid composition of lymphocytes, and other immune cells, is altered according to the fatty acid composition of the diet that can modulate immune response. Healthy fats are found in deep sea fishes, salmon, grass-fed beef, eggs, raw nuts and seeds, avocado, coconut, and olive and other oils.

Sugar is a food that works directly against the immune system. For each teaspoon of refined sugar consumed, immunity is lowered for six hours. It is best to avoid added sugar in general, especially if youre trying to fight or avoid infection.

Dairy is mucous-forming even for those without sensitivity, so is best to be avoided during illness or for prevention.

When we get a minimum of eight hours of sleep that starts by 10 p.m., we are allowing our bodies to rest and repair from the days efforts. If we are going to bed late or not getting adequate sleep, we are setting ourselves up to have lowered defenses. Studies show that while moderate exercise enhances immune function, high-intensity physical activity and periods of heavy training can suppress various immune response parameters.

We also know that cortisol, the primary stress hormone, has two primary jobs: to manage inflammation and to respond to physiological or emotional stress. Because the flight, fight or freeze response is more related to survival, our bodies will preferentially push cortisol down the stress pathway if given the choice. (It matters less if you have a cold if youve been eaten by a saber-toothed tiger!) The inflammation cascade is part of the immune system thats why you get achey with the flu. If stress and worry are a constant part of our day, we have less physiological tools for a healthy immune response.

Fear is a natural response to something threatening like the coronavirus itself, not to mention the global response and media coverage. There are probably many people who have had it or will get it and have a more mild response, not dissimilar to the annual flu. Germs and viruses are always around us; there is constant exposure. It is not the bug that determines if we get sick its our milieu that contributes to that probability. By eating healthy foods, getting rest and relating to stress in whatever way works for you, you are supporting your internal environment to do what it does best protect you with a balanced immune response.

Nicola Dehlinger is a naturopathic doctor at Pura Vida Natural Healthcare in Durango. She can be reached at 426-1684 or http://www.puravidahealthcare.com.

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Boost your immunity with diet, rest - The Durango Herald

When uncertainty is high, few things are more reassuring than having a plan to follow.

By Gaurav Gupta

Change is hard and complex, and changing the behaviors of millions of people is especially so. It is seductive to try to make it simple or at least more defined and straightforward. For the millions of people who decide to go on a diet each year, for example, following a program like Atkins or Paleo is a straightforward way to get started. For the business leaders who are looking to make their businesses more efficient, more effective or more nimble, particularly when prompted by external events like the current global pandemic, following a methodology like Six Sigma or Agile similarly provides a seemingly easy way to get started and a roadmap to follow. When uncertainty is high, few things are more reassuring than having a plan to follow.

There are successful stories to look to for inspiration and a well-documented process to follow that requires little upfront thought and planning. But for every company, like GE, that was successful in driving change through Six Sigma, there are countless others that were not as successful or successful at all. For every successful Atkins weight loss victory there are countless people who started and stopped achieving no meaningful results.

The data below shows searches on Google for some popular management techniques and diets. These searches are a proxy for the popularity of these methodologies and show a dramatic decline in the popularity of Six Sigma and Quality Circles. We can see that Agile still has some runway. One possibility for this trend of a rise in popularity followed by a gradual decline, is that these methodologies are simply being replaced by newer, more effective ones. Another hypothesis is that these methodologies got popular on the backs of some great successes but eventually were found to not be universally effective.

Google search data

The reality may well be a combination of both. What is clear is that many organizations, in their quest to find easy answers to the complex questions inherent in managing a modern-day business, turn to the most popular ideas of the day and mostly fail to see any real benefits. None of these methodologies are inherently bad or invaluable if they didnt work in at least some scenarios, they would never have gotten so popular. However, once popularized they are stretched in their application or implemented in a manner that reduces the concept to some seemingly sensible but limiting techniques that are implemented without a robust understanding of the underlying ideas.

So, before jumping on the bandwagon of Agile or 360 feedback (or the latest diet) there are a few questions you should ask yourself:

Why are we doing this and how will our business performance be improved?

While it might seem obvious at the start, once the teams have been spun up, the budgets established, the implementation timeline determined and the objectives cascaded to each unit, function and department, the goals are often no longer clear. When a process is so well established, it becomes easy to default to. There is a risk of operating on a sort of autopilot looking at procedural metrics and losing sight of the business goals and how the context may have shifted since the start of the whole effort. Companies start to focus on how many Six Sigma black belts have been trained or how many projects have been completed, instead of focusing on the business impact of these efforts. This is especially true in rapidly changing environments where it can be difficult to tease out the impact of the efforts. Worse still, often the reasons for following a particular management fad is the fear of missing out on some terrific benefit that everyone else is realizing. A few years ago, in a conversation about the future manufacturing footprint, a leader of a large food business admitted that the main reason behind pursuing a large investment in a Chinese facility was that everyone else was doing so. This may well have been the right decision, but it was certainly not made based on robust analysis of the available information.

What are the principles behind the approach?

In an increasing fast paced world, success is contingent on many employees actively engaged in making things better. As my colleague Justin Wasserman remarks, Operational excellence can be achieved through engagement instead of enforcement. Engagement requires more than an understanding of processes and methods; it requires an understanding and commitment to the principles and ideas followed by actual actions and behaviors. Almost all management methodologies originated from some principles and specific goals that the company that developed them was looking to achieve. For example, at its heart, Lean is about focusing on activities that add value to a customer. This can mean different things in different businesses, but too often businesses jump right into techniques and methods without reflecting on the principles and goals that underpin them. A one size approach may fit most, many, or hardly anyone at all. It could be highly dependent upon what youre trying to accomplish.

I worked with a paper and pulp company which, in its quest to be more efficient, implemented a Lean program. The Lean methodology, which originated from Toyota, was designed for the automobile industry which has an almost infinite number of different products models, configurations, colors and the like. By contrast, a manufacturer of corrugated paper has just a few. For an automobile manufacturer, minimizing working inventory is critical you dont want to be stuck with a lot of clutch assemblies if consumer interest moves further to automatic transmissions. However, the downside to minimizing working inventory is that the supply chain is not as resilient and you increase the probability of lost production from missing components or materials. For a paper company, this lost time is far more valuable than the reduction in working inventory. By implementing a method (to reduce working inventory) rather than adoptingthe principle (focus on what adds value to the customer) the company actually became less efficient.

Which parts of this approach is relevant to our business?

Another way to stay focused on relevance to your business is to ask which techniques/methods are actually relevant to solving your biggest challenges. In the previous example, some aspects of Lean manufacturing such as reducing product waste were highly relevant, whereas others were not. Another version of this is to understand which functions or departments are likely to benefit from the methodology. The iterative approach that is the hallmark of the Agile methodology may be highly effective for sales or product development but may be less so for customer service or human resources.

What is the most effective way to implement the approach?

Even when the methodology checks out to be a good fit with the needs of your business, poor execution can undermine the effectiveness of its implementation. Companies often rely on newly created departments or technical experts who are steeped in the methodology to lead the implementation. This can backfire, as these individuals are typically highly committed to the approach and can fail to see the limitations, overlook the essential step of creating strong buy-in, and can push too far too fast, leading to disruption and cynicism. Starting from the underlying principles and an understanding of which aspects of the approach are most relevant to the business allows leaders to develop an implementation plan that integrates with the business operations, includes a clear articulation of the benefits to be realized, demonstrates early success and engages employees through early and active participation.

New and popular management approaches and ideas can be very useful for businesses in keeping pace with the rate of change. However, beware of the frequency with which these ideas and concepts get replaced with a rigid methodology and tools. These techniques so often get blindly applied without a robust understanding of the underlying principles or without a clear sense of connection to the real business challenges, all of which, not surprisingly, is highly ineffective at making any meaningful change.

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Silver Bullets Are Seductive But Unhelpful Especially In Uncertain Times - Forbes

Dr. Levy, senior physician in medicine and genetics at Boston Children's Hospital and professor of pediatrics at Harvard Medical School, is being honored for his many years of groundbreaking work with patients who have genetic metabolic diseases including phenylketonuria (PKU), homocystinuria, cobalamin metabolic disorder, and others; as well as for his training and mentoring of the next generation of genetics service providers; and for his major contributions to the development of newborn screening in the United States and around the world.

Dr. Levy's medical career spans more than 60 years. He hasmentored over 60 medical genetics fellows; published more than 400 research articles, reviews, book chapters, and proceedings from research meetings; written 2 books and created 2 educational videos for patients and clinicians; served on editorial boards and as a reviewer for numerous prominent research journals; and founded and formerly directed both the Maternal PKU Program and the Inborn Errors of Metabolism/PKU Program at Boston Children's Hospital.

"Harvey Levy is a physician scientist who has been instrumental in the development of newborn screening programs for metabolic diseases," said former ACMG Executive Director Dr. Michael S. Watson, FACMG. "Of particular importance has been his melding of knowledge of clinical genetics, population genetics and metabolic diseases to identify critical issues in the transition from a disease-based understanding of particular metabolic diseases to a population-based prevention program that has had enormous impact on hundreds of newborns in the United States."

"We take newborn screening for granted now," said Gerard Berry, MD, director of the Metabolism Program and professor of pediatrics at Harvard Medical School. "There are laws in different states that babies need to be screened for certain diseases. But when Harvey began, this was uncharted territory. People didn't understand the power of newborn screening and how it could change lives by allowing someone to get on a diet or a medication that they need to take for life in order to be healthy. Harvey played a major role in allowing all of this to come to fruition. These same individuals, who might have been institutionalized years ago because of severe intellectual disability, are now students in elite colleges. Harvey possesses insight and super-ability to understand what is really important for healthcare. Newborn screening is one of the major healthcare successes of the previous centurymaybe the most important healthcare success. And Harvey was part of a group of unique individuals who helped to see that through."

The news that he had received the David L. Rimoin Lifetime Achievement Award came to Dr. Levy as a delightful surprise. "This means a great deal to me because of the ACMG, where I've been an active member for a number of years," Levy shared. "It's a wonderful organization full of outstanding individuals, so to be in that company is particularly gratifying. And it's very, very nice to be appreciated."

"The Rimoin family is proud to recognize Dr. Harvey L. Levy, whose outstanding work includes studies that formed the basis for newborn metabolic screening, the discovery of the first human vitamin B12defect and the establishment of cobalamin defects, and the development of Maternal PKU programs," said Dr. Ann Garber, David Rimoin's surviving spouse."Based on his scientific accomplishments, along with his remarkable integrity, empathy and collaboration, our family is pleased to honor Dr. Levy with the David L. Rimoin Lifetime Achievement Award."

Beyond his list of academic achievements and leadership positions, the nominations for Dr. Levy to receive this award stressed his abounding generosity of time, knowledge and skill while working with patients, families and the broad range of clinical providers and researchers who have collaborated with him.

"He's dedicated himself to the study of PKU and metabolic disorders with an energy and intellect and soul that is extraordinary," said neuropsychologist Susan Waisbren, PhD, a professor of psychology at Harvard Medical School and Dr. Levy's long-time collaborator at Boston Children's Hospital Metabolism Clinic. "One of the qualities I've always found striking is the respect he has for professions outside of medicine. In his mind, every member of the clinical team is important. He truly feels this and it shows in his academic as well as clinical work. He has included as co-authors psychologists, dieticians, social workers, genetic counselors, nurses, administrators, secretaries, and parents.

"The patients adore him, always," she added, "and they recognize a certain compassion and ability to see the whole person, not just the metabolic disorder."

"Harvey is one of those special individuals who one may encounteronce in a lifetime," said Dr. Levy's collaborator at Boston Children's Hospital, Dr. Berry. "He's much more than an accomplished geneticistand investigator.First and foremost, he's a very endearing individual with a wonderful bedside manner, and he's beloved by patients and families whom he's cared for over the years. Harvey goes out of his way to make things better for patients and their families."

As an example, Dr. Berry, who has knownDr. Levy for several decades, recalled a case around 15 years ago, when a baby had been born with PKU in a suburban hospital outside of Boston. "Without telling anyone, Harvey drove to the hospital just to say hello to the new parents and to see the baby," Dr. Berry recounted. "He didn't need to do that. Everything was already in place, people were already taking care of what needed to be done, but he felt compelled to drive out there on a Friday evening to say hello."

Harvey L. Levy was born in Augusta, Georgia in 1935, the eldest of three sons. His father owned a one-room mercantile that supplied clothing to families of the surrounding area, which comprised mostly farmland during that period. His mother, who was a homemaker, graduated from Hunter College and served as a technician in a research laboratory in New York before her marriage. He credits her with some of his initial interest in research.

"I was a guy who was looking for answers to things, so I was always interested in science. And I particularly liked chemistry," Dr. Levy recalled. "My mother was a very intelligent person and very interested in education and music and arts, and also interested in science. I talked with my mother quite a bit about science. So, I think she had a feeling that maybe it would be a good idea for me to be a doctor."

Dr. Levy began studying history as an undergraduate student at Emory University and then switched to an early admission program at the Medical College of Georgia. One of his medical school professors, the famous Dr. Victor Vaughan, headed the department of pediatrics and had a profound influence on the direction of Dr. Levy's career. "I was always interested in pediatrics because of its developmental aspects," explained Dr. Levy. "I felt that if I was going to do something in terms of disease, preventing or helping patients in a significant way, I had to start early, and the earlier the better."

After completing his medical degree in 1960, Dr. Levy served an internship in pediatrics at the Boston City Hospital under Dr.Sydney Gellis, a renowned teacher of pediatrics. Following the internship he moved to New York and the Columbia-Presbyterian Medical Center, where he spent a year under Dr. Dorothy Anderson, the discoverer of cystic fibrosis. Then, as world events escalated toward the start of the Vietnam War, he was drafted and served 2 years in the Unites States Navy as a medical officer stationed in the Philippines.

His introduction to genetics came when he returned to his medical training in 1964 as a second-year pediatrics resident at Johns Hopkins University, where he met the pioneering pediatric clinical geneticist Dr. Barton Childs. What he learned from Dr. Childs about DNA triggered memories of an earlier time, and brought forth questions that further defined Dr. Levy's future career.

"If I go back to my childhood, my upbringing, I had three cousins from one of my father's brothers, whose family we were very close to, and all of these cousins were developmentally disabled," Dr. Levy said. " No reason was given for their disability and I always thought if I got into genetics, then maybe I could discover the causes of brain disease, particularly intellectual disability, and maybe I could influence the prevention of it."

Dr. Levy returned to Boston, where he served as Chief Resident in Pediatrics back at the Boston City Hospital. During that year he heard a lecture by Dr. Mary Efron, director of the Amino Acid Laboratory at Massachusetts General Hospital, in which she described her studies on metabolic disorders and their enzymatic defects as well as how newborn screening was helping clinicians to identify infants with these disorders so they could receive immediate preventive treatment.

"I became so fascinated with that. It was just absolutely the thing that I really wanted to do," recalled Dr. Levy. "Here was chemistry, biochemistry, genetics, and the prevention of disease! So I asked Dr. Efron if I could do a fellowship with her, which resulted in an NIH-funded fellowship at Massachusetts General Hospital. And that began the journey that has continued to this day."

One cold, fateful Friday afternoon while he was working in Dr. Efron's lab, a telephone call came from Dr. Robert MacCready, director of the Massachusetts Newborn Screening Program. Dr. MacCready asked if someone could come to the screening lab to look at an unusual screening result. Dr. Efron was ill, so Dr. Levy rode his bicycle seven miles across town to the State Laboratory Institute, where he recognized the unusual spot on the paper chromatogram test as a high level of methionine, the hallmark of a genetic disorder he had recently learned about called homocystinuria.

"I called the baby's doctor and asked if I could see the baby at the Massachusetts General Hospital the following Monday," Dr. Levy recalled. "The family and baby came that Monday and I confirmed that the infant indeed had homocystinuria. I asked if they had other children, and was told, 'Yes, we have a daughter.' And I asked if she was ok, and they said she was fine. I asked to see her and she was brought to the next visit, where I immediately recognized that she was developmentally delayed and had other features of homocystinuria that had only recently been described. She was born before screening for homocystinuria had begun. So that launched me into the field of methionine metabolism and some very interesting new areas of research." Much of this research was in collaboration with the late Dr. Harvey Mudd of the NIH, who was the world's foremost authority on methionine and on sulfur amino acid metabolism in general.

Dr. Efron passed away and Dr. Levy assumed Dr. Efron's position as consultant to the Massachusetts Newborn Screening Program and, in 1972, was appointed Director of the program. Four years later, he became Chief of Biochemical Genetics for the New England Newborn Screening Program, a position he held until 1997. Throughout this period, Dr. Levy collaborated with the famed, late microbiologist Robert Guthrie, MD, PhD, of Buffalo, New York, who had established newborn screening with his invention of the PKU test. During this time, he also continued to conduct research and to diagnose and treat patients with metabolic disorders at the Massachusetts General Hospital. An extraordinary influence for Dr. Levy during this time, and continuing to the present, is the internationally famous Canadian biochemical geneticist Dr. Charles Scriver, with whom Dr. Levy has often collaborated.

Toward the end of the 1970's Dr. Levy moved to Boston Children's Hospital, where he transformed the PKU Clinic it into a larger, comprehensive clinicthe Inborn Errors of Metabolism clinicthat now sees patients and families from around the world who are affected by a range of diseases: PKU, galactosemia, histidinemia, methylmalonic acidemia, problems with vitamin B12 metabolism and many other disorders. The hospital recently named the metabolic program after Dr. Levy.

At Boston Children's Hospital Dr. Levy became concerned about infants born to mothers who have genetic metabolic disease. "Before we began newborn screening girls who had PKU became delayed in their mental development, so very few bore children," Dr. Levy explained. "But now that we were treating them from infancy, they were bearing children. Even though their babies were genetically normal, they would be born with multiple severe problems if the mothers were not strictly treated for PKU during the pregnancies. So, with an extraordinary group of very talented professionals, including psychologists, nutritionists, a nurse, and a social worker, as well as physicians, we organized the New England Maternal PKU Program and followed these women on very strict dietary treatment throughout their pregnancies. We found that this regimen prevented many of these problems that the babies would otherwise have."

Today Dr. Levy is considered one of the foremost proponents worldwide for newborn screening. He led a successful effort in Massachusetts to expand newborn metabolic screening with new technology so that 20 to 30 disorders of amino acid, organic acid and fatty acid metabolism could be included rather than only 5 or 6 disorders previously screened. Within the ACMG, Dr. Levy led the effort to develop "ACT Sheets," one-page synopses of the newborn screened metabolic disorders so that physicians caring for infants can easily read an explanation of the biochemical, clinical and treatment characteristics of the disorders when contacted by a newborn screening program about an abnormality. As part of a contract funded by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), Dr. Levy began and led the Newborn Screening Translational Research Network of the ACMG.

Though many of his contemporaries have retired, Dr. Levy continues to lead research efforts that examine the long-term outcomes of expanded newborn screening using tandem mass spectrometryincluding the medical, biochemical and neuropsychological outcomes in relation to early treatment. He is also involved with clinical trials to develop new therapies for PKU and homocystinuria. Dr. Levy is driven to continue his work because there is still much work to do. "The fact that we've had to rely on complicated diets that alter the lives of patients so they cannot enjoy a normal meal with their family or their friends, they have to only be able to eat this very difficult diet, and also the fact that we still discover diseases for which we have no treatment, " he explained, "these are the issues that trouble me. There are still individuals we discover during newborn screening or we discover later on because we didn't screen for their disorder, and they have severe disorders for which we have no treatments. There are still metabolic diseases that are not being prevented."

Dr. Levy still spends time communicating face-to-face with patients. "If you have a new baby, in a room with the family, you have to present this very complicated story, and the family has no idea what this is about," he explained. "So, we spend a great deal of time explaining the biochemistry, the genetics, the problems that can occur and the treatments that can prevent these problems. Early on, we just thought about biochemistry. But today we become more involved in talking about the genes, because we think it's important for families to understand the origin of these disorders since at some point we are likely to talk to them about the possibility of gene therapy, actually introducing the normal gene into the child. So, they need to understand where the disorder comes from. It's a complicated and long process. The family will take in as much information as they can, but as you can imagine, a lot of what we tell them will be forgotten or not understood. So, we go over everything with them again, and for as many times as they need."

One of the most pleasing aspects of Dr. Levy's career, he recounted, has been working with wonderful and dedicated individualspsychologists, nutritionists, dieticians, nurses, social workers, coordinators, administratorsand within the community of clinicians and researchers who study metabolic genetic disorders, a "relatively small, cohesive group of delightful, brilliant people" as he describes them. "It's been an extraordinarily wonderful professional life, as gratifying as any professional life I could ever dream of," reflected Dr. Levy. "Little did I know when I started that I would have this kind of life and little did I know that I would be awarded with the awards and certainly nothing comparable to the David L. Rimoin Lifetime Achievement Award."

The David L. Rimoin Lifetime Achievement Award is the most prestigious award given by the ACMG Foundation. A committee of past presidents of the American College of Medical Genetics and Genomics selects the recipient following nominations, which come from the general membership.

About the ACMG Foundation for Genetic and Genomic Medicine

The ACMG Foundation for Genetic and Genomic Medicine, a 501(c)(3) nonprofit organization, is a community of supporters and contributors who understand the importance of medical genetics and genomics in healthcare. Established in 1992, the ACMG Foundation supports the American College of Medical Genetics and Genomics (ACMG) mission to "translate genes into health." Through its work, the ACMG Foundation fosters charitable giving, promotes training opportunities to attract future medical geneticists and genetic counselors to the field, shares information about medical genetics and genomics, and sponsors important research.To learn more and support the ACMG Foundation mission to create "Better Health through Genetics" visit http://www.acmgfoundation.org.

Note to editors: To arrange interviews with experts in medical genetics, contact ACMG Senior Director of Public Relations Kathy Moran, MBA at [emailprotected].

Kathy Moran, MBA[emailprotected]

SOURCE American College of Medical Genetics and Genomics

Original post:
Pediatrician and Geneticist Dr. Harvey Levy Receives 2020 David L. Rimoin Lifetime Achievement Award in Medical Genetics from the ACMG Foundation for...

All too often, like the boy who cried wolf, the word crisis is casually tossed about to grab attention or stir emotions. Unfortunately, crisis understates the imminent threat that the coronavirus outbreak poses to our personal and collective health and economic future.

We know almost instinctively what to do when floods or tornadoes strike, but many feel powerless in this pandemic. To contain the disease and minimize its effects, everyone must act to lead us through what lies ahead.

Foremost are personal efforts to protect your health and those around you. You have heard this before, but the single most effective thing you can do is wash your hands with soap and warm water frequently even up to once an hour. Cover your nose and mouth with a tissue or your elbow crook when you cough or sneeze. Avoid touching your eyes, nose and mouth. Eat a balanced diet that includes fruits and vegetables (frozen or canned) and get proper sleep.

If you are over 65 and or have pre-existing health conditions like lung disease, diabetes or are immunosuppressed, remain homebound and limit interaction. Social distancing is highly effective in limiting spread of the coronavirus. Healthy individuals age 50 to 65 are also at risk and must limit public interactions.

If you have flu-like symptoms, stay home for at least 24 hours after your fever is gone except to get medical care. Call your provider, urgent care clinic or emergency room before going in person. Medical personnel will advise you if you need to be evaluated in person. Frequently clean and disinfect hard surfaces and objects, such as doorknobs, countertops, touchscreens and cell phones.

Our traditional, heroic volunteerism in the face of a natural disaster can be tremendously beneficial, now more than ever. Young adults and teenagers can electronically organize groups to individually babysit for parents especially healthcare professionals, first responders, police, firefighters and food service workers who cannot work from home.

Visit your elderly homebound neighbors, either virtually or from outside, maintaining social distancing. Volunteer to prepare or pick up meals and deliver them to the homebound. If you have a favorite restaurant, offer to deliver meals for 1 or 2 hours a day for free. My husband and I are going to do this to help small businesses survive through the pandemic. One caveat, do not do volunteer work if you have a fever or cough!

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We need free and vastly more available coronavirus testing. As a former director of the Iowa Department of Public Health, I suggested more funding for the agency. A $525,000 appropriation was made to the State Hygienic Laboratory for testing kits; its possible more will be required.

Drive-by testing should be fast-tracked and implemented immediately. We need to know who has symptoms or is ill and how many are infected but asymptomatic. Restrictions on telemedicine should be temporarily lifted and all insurers should reimburse such care.

We should develop a volunteer healthcare workforce through temporary licensure of physicians, nurses and physicians assistants who have retired or whose licenses lapsed. My husband and I both former Army medical professionals would be willing to volunteer to reduce the potential burden on current health care personnel, as I am sure other former Army active duty and reserve members would.

Immunity should be granted to volunteer healthcare providers and expanded telehealth service unless conduct is significantly outside the standard of care. This approach also should become part of our preparedness planning. State and federal lawmakers should also loosen unemployment compensation rules for those who are temporarily out of work or see their work hours reduced; temporarily increase in SNAP benefits and low-interest small business loans; temporarily defer student loan repayments; and suspend FICA tax collection for up to 90 days.

Our best selves prevail in any disaster because we come together to help others. A pandemic differs because we must maintain distance and hygiene, but not in how we respond in spirit and action. Iowa and America have always risen to the challenge and we will do so again.

Mariannette Miller-Meeks represents District 41 in the Iowa Senate. She is an ophthalmologist, former president of the Iowa Medical Society and former director of the Iowa Department of Public Health.

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To fight coronavirus in Iowa: Good hygiene, free testing, more telemedicine - The Gazette

The coronavirus outbreak has at least for now completely transformed life as we know it, and that can be a very scary thing.

In this time of rapid change and uncertainty, it can be comforting to remind ourselves that we have actually been through things like this before, and weve gotten through it and yes, life did eventually return to normal.

For instance, take the Spanish flu outbreak of 1918-19, which killed tens of millions worldwide, including 33 in Orange County an epidemic far worse than Covid-19 has been, at least so far.

How did our community weather that storm?

UNC has created a digital initiative calledDocumenting the American South, dedicated to gathering documents related to Southern history, literature, and culture. Part of the collection includes a summary of Orange Countys response to the flu outbreak, written shortly after by Annie Sutton Cameron as part of a largerRecord of the War Activities in Orange County, North Carolina, 1917-1919.(Thanks to Mia Day Burroughs for discovering the document in her research.)

Heres how Cameron described what happened when the epidemic hit Orange County including the extreme and quick steps taken by local health officials (notably the closing of all churches, schools, [and] theatres during the fall of 1918), as well as the heroic work of individuals to help those in need.

Shortly after the opening of the University for the year 1918-19 cases of Spanish influenza began to appear. In a short while scores had been stricken with the disease. In the very first days of the epidemic the Red Cross volunteered its services and began helping the physicians. The co-eds of the University were called upon to make face masks for the doctors and nurses in the various emergency hospitals. Two hundred and eighty-six masks were made, as well as one hundred and seventy arm bands for the attendants in the hospital. For weeks Miss Helen Shell, Miss Katherine Bourne and Mrs. Kent Brown did volunteer nursing in the University hospital, while other women were aiding stricken families all over the village. As the epidemic spread to Carrboro the need for volunteer nurses became more imperative. A committee composed of Misses Josie Pritchard and Helen Shell and Mrs. Kent Brown and Mrs. William deB. MacNider, assisted by others, worked night and day relieving the distressing conditions of the stricken people. Mr. J. S. Carr gave the use of the club rooms for a diet kitchen, paying all expenses for the maintenance of the same. Mrs. R. B. Lawson and Mrs. Arthur Blackwood volunteered to take charge of the kitchen and for two weeks served nourishing meals of soup, bread and milk. At least seven gallons of soup were served daily. Each morning two orderlies visited the various homes of the village to obtain an accurate report of the needs of the people, so that these needs might be supplied. This record would be incomplete without mentioning Miss Roper, who left a remunerative position as nurse for Mrs. McDade and ministered to the University boys afflicted with influenza. Although ill herself, for days she stayed at her post until forced by the physicians to give up. In a few days pneumonia developed, and this brave woman died, having truly given her life for others. (pp 26-7)

Early in October, 1918, Dr. D. H. Hill, State Chairman of the Council of Defense, sent letters to all County Chairmen warning them of the spread of Spanish influenza, which was threatening the whole country. In this letter he made suggestions as to what steps should be taken, etc.

In accordance with this, Mr. J. C. Webb called a meeting of the representative men to meet with the County Commissioners and plans were made for Relief Work. It was realized at this meeting that there was no County Board of Health, and so one was created, with Dr. Spoon of Hillsboro as County Health Officer, who with the following constitute the Board of Health: Dr. B. B. Lloyd; Ed N. Cates Chmn. Co. Board of Commissioners; Jeff Turner, Mayor of Hillsboro; R. H. Claytor, County Supt. of Schools.

Mr. T. N. Webb was appointed County Chairman of the Relief Work, with Dr. J. S. Spurgeon to represent the Hillsboro School District. The other districts were as follows:

Mr. Sterling Browning, representing the Eno District.

Mr. Carl Forrest, representing the Efland District.

Mr. John P. Hughes, representing the Cedar Grove District.

Mr. Eubanks, representing the Chapel Hill District.

Rev. Harvey Bradshaw was appointed to have charge of the town of Hillsboro and Mr. C. H. Robertson that of West End.

On October 7, the Board of Health ordered the closing of all churches, schools, theatres, etc., and forbade all meetings of every kind, in order to prevent, if possible, a spread of the disease which had already broken out in the community.

With the appearance of the first case, assistance was given in nursing and furnishing suitable nourishment and necessities by citizens of the town, and Dr. Spurgeons family, Rev. Mr. Bradshaw, Miss Nellie Russell, and Mr. Chester Turner were among the first to render aid and continued to do all in their power.

When the epidemic spread to the Eno Mill district, the officials of the mill opened a diet kitchen at the West Hill school, and financed it for about seven weeks. Miss Elizabeth Cornelius, Home Demonstration Agent, was placed in charge of this undertaking and proved herself most efficient and faithful throughout the long siege. Without her it could not have been accomplished. Mr. C. H. Robertson supervised this work and rendered every assistance possible, and as chairman of West Hill was untiring in his efforts to do everything in his power. Misses Emma Robertson and Mildred Durham were Miss Cornelius assistants during the entire time and Miss Rebecca Wall also rendered valuable aid for several weeks. As many as 150 people were fed daily for some time, and an average of 90 for most of the time. Not only the sick were furnished with nourishment, but the families with no one to cook or provide for them were furnished with the proper diet. Mrs. Emerson and Miss Allie Graham were secured by the Mill to do nursing, and Miss Duncan, the deaconess at the Mills, with these two, rendered most valuable service and gave unstintingly of their time and strength. After preparing the nourishment the ladies at the diet kitchen went with the nurses to deliver it where it was needed.

Eno Mill also secured another trained nurse, Miss Whitfield, and Bellevue Mill secured Miss Smith from Durham. Mr. Chester Turner and Ross Turner (colored) did noble service as volunteer nurses wherever the need arose.

As County Chairman, Mr. T. H. Webb was most active and efficient and untiring in his labors, and was especially helpful when the need was great in the Bellevue district. He and Mrs. Webb sent food and clothing to those in need.

Rev. Mr. Bradshaw worked long and faithfully when the epidemic extended into the town, collecting and delivering nourishment furnished and made by ladies throughout the town. He was assisted in this by Mrs. J. C. Webb driving him to the homes where he had to go, and when it was impossible for Mrs. Webb to continue, a car and driver were furnished by Mr. J. C. Webb for this purpose until the epidemic was past.

As soon as the need for nurses was felt, Miss Henrietta Collins volunteered to go wherever needed, and later Miss Virgie Cole volunteered, but they were not called upon to serve.

The Relief Work was organized and carried on by the County Board of Health, but most if not all workers were members of the Red Cross. Below are the minutes of a meeting held in connection with this work.

A special meeting of the Executive Committee of the Red Cross was held October 26th, at 10:00 oclock in Major Grahams office. There were present Major Graham, Mr. Robertson, Mrs. J. C. Webb, Mrs. W. H. Webb, Mr. T. N. Webb, Mr. N. W. Brown, Miss H. P. Collins, Mr. Bradshaw and Dr. Spurgeon. This meeting was for the purpose of co-operating with the Committee for the Relief of the Influenza Epidemic, of which committee Mr. T. N. Webb is County Chairman. A motion was carried that there be appointed a chairman of a Nursing Committee of each of the two school districts to whom application may be made for nurses to serve anywhere in our jurisdiction, a record of volunteers to be reported to the Secretary, who was to keep it. Mr. T. N. Webb was appointed Chairman of this Committee for the West Hill School District and Miss Russell for the Hillsboro District.

A canvass of the town was made the day of this Red Cross meeting to tell the people of the need for nurses and to ask for volunteers who might be called upon if necessary. The Red Cross was asked to furnish gauze face masks and this work was done at the work room as long as a supply was needed.

The ladies of the Red Cross were asked to make garments for the sick in emergency cases, and this was gladly done at a moments notice. People were very generous in furnishing butter-milk and soup not only those in town but a quantity of milk was furnished by people out of town, especially east of town. The Rev. Mr. Hester, Mr. and Mrs. C. H. Robertson, and Mrs. J. C. Webb alternatively collected this milk for use at West Hill and in town.

After Christmas a second epidemic of Spanish influenza spread through the county and was very bad at Cedar Grove, Efland and Hillsboro. However, the schools and churches did not close and the epidemic gradually died down.(pp 75-79)

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Weathering the Storm: Outbreaks in Chapel Hill, from Spanish Flu to COVID-19 - Chapelboro.com

However, she quickly added, Maintaining weight loss can get easier over time. Over time, less intentional effort, though not no effort, is needed to be successful. After about two years, healthy eating habits become part of the routine. Healthy choices become more automatic the longer people continue to make them. They feel weird when they dont.

On the other hand, perfection is not realistic and can be self-defeating, Dr. Phelan said. Successful maintainers know there will be lapses. But they also know they can recover from lapses and how to get back on track. They accept slips and dont engage in black-and-white thinking like I was bad, an attitude that is self-defeating. Rather, they know there will be ups and downs, and they have a plan for coping with lapses thats empowering.

A personal example from one who lost a third of her body weight and kept it off for half a century: I anticipate and plan for the times when I expect to be confronted with culinary largess. Im a little more abstemious beforehand, enjoy the indulgence and get back to normal the next day.

Rather than constant deprivation and self-denial, I practice moderation. The studys co-author, Gary Foster, who is chief scientific officer for WW, explained that in the WW program, Everything is on the menu. Fad diets are overly restrictive, which dooms them from the onset. We advocate moderation, were anti-dieting. People have to find habits and routines that make long-term weight loss sustainable.

And as many of the successful weight maintainers in the study reported, time and practice have permanently modified what I find appealing, so I rarely feel deprived and have less need to exercise self-denial all the time. I do admit, though, that Im less good at ignoring cravings than many in the new study are. Im more likely to give in but control the amount I consume.

What I may be best at is monitoring my weight. I weigh myself every day and keep within a range of two or three pounds. Nearly all the successful maintainers in the study weigh themselves weekly or more often, which makes it easier to self-correct before the numbers on the scale rise significantly.

Dr. Foster said, Whats on your mind is as important as whats on your plate. Weight management is something you do for yourself because youre valuable, youre worth taking care of.

See the rest here:
How to Lose Weight and Keep It Off - The New York Times

March 2020 has already reserved a dubious position for itself in history. As each one of us comes to terms with the coronavirus reality were all suddenly faced with, each cough, sneeze, ache, and pain is being placed under a microscope. Self-isolation has quickly become the name of the game in terms of containment, so in many ways, it really doesnt matter if youre feeling sick at this particular moment. Its still imperative that you stay home and avoid contact with others.

That being said, a new study is making a pretty strong case that now is not the time to try out a keto diet while you binge Netflix and dust off Monopoly to pass the time. Researchers in Australia have found compelling evidence across social media that a ketogenic diet can cause several flu-like symptoms during the first few weeks. Common symptoms of the keto-flu include fatigue, nausea, lack of energy, body aches, dizziness, faintness, and heart palpitations. Quite a few of those symptoms are also associated with Covid-19.

Right now everyone is on edge, its impossible not to be considering the situation were all in. Adding extra stress to your body, and possibly wrongly convincing yourself youve come down with Coronavirus because of a recent keto regiment isnt a good idea right now. There will be plenty of time to work on our summer appearances once this ordeal is under control and in the rearview mirror.

Keto-flu symptoms usually appear quickly after starting the diet, peaking within seven days and then disappearing over the coming weeks.

The keto diet, or a high-fat & low-carb approach to eating, has quickly become among the hottest fitness trends in recent years thanks to its relatively quick results when it comes to burning fat. Moreover, keto diet proponents believe it can also strengthen ones memory and even help fight diabetes or cancer.

The keto-flu itself isnt exactly breaking news, many dieters have reported a variety of adverse bodily reactions when first trying out a ketogenic diet. So, in an effort to attain authentic first hand accounts of the keto-flu, this studys authors took a novel approach. They searched through 43 online forums (social media posts & platforms) that mentioned the keto-flu and put together 101 written accounts of relevant symptoms, their severity, and their duration.

The experiences of symptoms by many people strengthens the evidence for side-effects following the initiation of a ketogenic diet, says Dr. Emmanuelle Bostock of the Menzies Institute for Medical Research of the University of Tasmania, in a press release. These consumers have the most immediate experience of effects and side-effects and many choose to report and share these in online forums.

We focused on social media because of its widespread use for discussion of health topics, which makes it practical to harness the experience of people who have tried the treatment in question, Dr. Bostock continues. In the present study, we responsibly and respectfully used public domain online forum posts and analyzed their content to produce new insights into side-effects of the ketogenic diet.

Just like prior research had found, social media users complained of multiple symptoms; headaches, difficulty concentrating, stomach problems, and even classic flu-symptoms (sneezing, stuffy nose). Most of the time users reported more than just one of these symptoms.

If you find yourself wondering if youre dealing with a keto-flu or legitimate coronavirus symptoms, the keto-flu is not known to cause an increase in body temperature. So, that appears to be a sure-fire way to make a distinction.

To be clear, in a vacuum the keto-flu really isnt anything to stress out about. Its just how many peoples bodies react to switching over to a keto diet. All things considered, the symptoms are relatively mild and disappear, in most cases, within two weeks.

Beyond the keto diet, and even Covid-19, this set of research is especially interesting because it illustrates just how helpful social media can be in regards to conducting research. In all likelihood, well see more and more studies using social media to aid in data collection efforts and first-hand accounts.

Normally the keto-flu is just a bump in the road on ones fitness or weight-loss journey, but these days life is anything but normal. Many of us already have hypochondriac tendencies, often exacerbated by frequent visits to WebMD, and the coronavirus is amplifying the anxiety. With all of this in mind, the added strain that a new keto-diet can put on the body, coupled with the possibility of worrying flu-like symptoms appearing, make it a venture not worth taking right now.

The full study can be found here, published in Frontiers in Nutrition.

Read more here:
This trendy diet will not help you during the Coronavirus pandemic - Ladders

3 Tested Ways to Achieve High Work Performance and Deep Thinking

My wife and I just had our firstborn child, so figuring out how to maintain high performance while on limitedsleep makes a ton of sense for me right now (there isnt enough coffee in Starbucks to keep me caffeinated).Andwhile we all want to walk around like Bradley Cooper in Limitless, operating at stunningly efficient levels in a state of total human optimization, the reality is, well, were human.

Everybody knows that great habits lead to better results if you're looking to change your habits. That means getting a good nights rest, eating healthyand having a positive attitude. Habits are important, given that 69 percentof American adults say that health care is a significant source of stress, according to a November 2019 survey by the American Psychological Association. Moreover, 56 percent reporting beingstressed over the nations political climate. Americans also dont get enough sleep. A 2018 survey by National Sleep Foundation found that only 10 percentof U.S. adults prioritize sleep over other daily activities. For people who have excellent sleep health, 90 percentsaid they are very effective each day.

A nutritious diet, ample rest and a positive outlook are what remindus thatwe can determine ourquality of life more than external stimuli or events beyond our influence. Here are ways to boost your performance at work and life in general.

Speaking of Limitless, increasing numbers ofpeople are taking supplements to ensure their mind and body can accomplish more. Smart drugs, or nootropics, are particularlypopular among individuals who seek an edge in daily performance. The global dietary supplements market will grow 7.8 percentannually to $195 billion by 2025, according to Grand View Research, and North America leads the way as the largest market for these products. The market is driven by the hectic work schedules among working individuals coupled with fluctuations in diet intervals, according to the firms May 2019 report.

As we all know, a full day requires concentration, dedication and nutrition.AsMau Pan, co-founder of Nuoptimal, explains,Nootropics can be the catalyst to achieving greater productivity and happiness in your daily life. When taking the right combination of ingredients, they can boost work output and even promote long-term brain health." I agree.

Planning how you spend time leads to better results. More importantly, youre less likely to get overwhelmed by a chorus of tasks. Peak performance isnt possible when youre interrupted by emails, texts and social-media notifications.I like the Pomodoro Technique for staying on track. Its a time-management strategy created by Francesco Cirillo in the 1980s that uses a timer to break down work into intervals, traditionally 25 minutes in length, separated by short breaks of five-to-10 minutes. My preferred cycle is 40 minutes of work followed by 10 minutes of rest.

Everyone has 24 hours a day, but planning actually increases your productive time. By focusing on important tasks, youre able to reject less impactful and less meaningful activities. Think of it this way: Youre constantly saying no to alternative actions. If you choose unproductive activities, then youre saying no to working, to parenting, to running errands.

A January 2018 study by the University of Minnesota in Minneapolis (UMM) found that workers lose efficiency when they constantly switch from one task to another. Planning your day helps you to focus on the key task at hand until its finished. Our brains process tasks better one at a time, says the study'sco-author, Sophie Leroy, a former faculty member at UMM. Our brain truly tries to keep the interrupted work on our mind so that we dont forget about it.

Related: 7 Steps to Peak Performance in Business and Life

Interruptions lead to a downward spiral of frustrations, stress and ineffectiveness. Multitasking is destroying your ability for long, deep, cognitive thinking.Most of your distractions probably come from your phone and mobile apps, which steal an enormous amount of time, attention and productivity. Ive definitely felt, at times, an addictive tendency towards my phone, and I'm not alone. The average U.S. adult now spends three hours on their mobile devive each day. This study from Behavioral Health compares smartphone distractions to cocaine, suggesting startlingly similar side effects. Let that sink in.

This sounds somewhat counterintuitive, butI do enjoy a handful of mobile apps that help me focus and stay productive. Brain.FM is a cool one that gives you music that helps you focus, stay productive or sleep. Freedom is another one I like that lets you block any appor site that is a distraction.

The more time you spend on distractions, the less time youre spending on constructive acts. Dont let your smartphone make you dumb. Remove unnecessary apps so you can declutter your day and streamline your life, anddelete all notifications. And when working, set your phone to airplane mode.

Id love to hear your tips. Give me a shout on Twitter @andrewmedal.

Related:3 Tested Ways to Achieve High Work Performance and Deep ThinkingA Former Editor of 'Cosmopolitan' On Her Secret to (Almost) Infinite EnergyDhvani Bhanushali - The Pop Sensation and Million View Queen

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3 Tested Ways to Achieve High Work Performance and Deep Thinking - The Advocate

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