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Neuron Discovered That Suppresses Eating May Lead to Effective Diet Drugs – SciTechDaily
A CALCR cell found in mice may stop feeding without subsequential nauseating effects as well as influence the long term intake of food.
Ever eaten something, gotten sick and then didnt want to eat that food again because of how it made you feel? Thats because a signal from the gut to the brain produced that sickness, creating a taste aversion.
Conventional wisdom renders theres one circuit in the brain that suppresses eating it comes from the stomach and makes you feel sick if you activate it too hard. Eating a portioned meal makes your body happy, though, even while stimulating a signal to the brain to stop eating, according to Michigan Diabetes Research Centers director, Martin Myers Jr., M.D. Ph.D.
Therefore, there must be a circuit that stops normal feeding without the adverse effects, right? says Myers.
Now, a Cell Metabolism study may have discovered this second circuit in mice. Myers, Randy Seeley, Ph.D, the director of the Michigan Nutrition Obesity Research Center, and a team of researchers sought to better understand which part of the brain curbs appetite and which neurons play a role in making mice want to eat or not eat.
The gut-brain signal that suppresses appetite is triggered by a type of neuron, containing calcitonin receptor (CALCR), which lives in a structure of the hindbrain called the medulla. Interestingly enough, these neurons didnt need to be active in the brain for gut sickness to cause an aversive response.
This suggested we might be able to dissociate the brainstem systems that stop feeding from those that cause nausea, says Myers, whose group found they could genetically activate those CALCR neurons to do just that.
Since there are neurons that can suppress eating but also cause aversive effects, that must mean there are different types of neurons, or circuits, in the brain that can terminate feeding with differing emotional responses.
When the researchers inactivated the CALCR neurons, they were surprised to make another discovery, which contradicted the idea that the brain only controls short term meal sizes and consumption.
Turning these neurons off didnt only interfere with the suppression of feeding by gut signals, but it also caused an ongoing increase in food intake. The mice became obese, suggesting that the brainstem systems dont only control meal size, but the amount of food consumed long term. This created a predisposition to obesity because of the energy imbalance in the mice (more input than output).
Similarly, activating CALCR neurons decreased the mices food intake and body weight without any aversive gut effects. In the study, Myers and his team found another neuron, CCK, also decreased food intake and body weight but created an aversive internal response, unlike the CALCR neurons. The difference between the two neurons were found in their circuits.
CCK activates what we would call a yucky circuit, says Myers. The neurons activate a certain cell, CGRP cells, which create that sick feeling. Unlike CCK, activated CALCR neurons follow a yummy circuit, activating non-CGRP cells.
Obesity affects more than one-third of the adult population in developed countries, which can lead to diabetes or other serious, long-term health conditions like heart disease, explains Myers, who is also the director of MDiabetes.
Unfortunately, many diet drugs work, but they make people feel nauseous after they take them. Obesity remains a condition difficult to pharmaceutically manage, since the treatment options have limited therapeutic utility. A drug that turns on CALCR and turns off CGRP could greatly benefit patients with obesity by suppressing feeding and creating a long term control of food intake and body weight.
If we could figure out a drug for individuals with obesity that suppresses food intake to produce long term weight loss without the negative side effects, it could absolutely change someones life, says Myers.
Reference: Calcitonin Receptor Neurons in the Mouse Nucleus Tractus Solitarius Control Energy Balance via the Non-aversive Suppression of Feeding by Wenwen Cheng, Ian Gonzalez, Warren Pan, Anthony H. Tsang, Jessica Adams, Ermelinda Ndoka, Desiree Gordian, Basma Khoury, Karen Roelofs, Simon S. Evers, Andrew MacKinnon, Shuangcheng Wu, Henriette Frikke-Schmidt, Jonathan N. Flak, James L. Trevaskis, Christopher J. Rhodes, So-ichiro Fukada, Randy J. Seeley, Darleen A. Sandoval, David P.Olson, Clemence Blouet and Martin G. Myers Jr., 16 January 2020, Cell Metabolism.DOI: 10.1016/j.cmet.2019.12.012
Disclosures: This study was funded by National Institutes of Health and AstraZeneca. Martin Myers Jr., M.D., Ph.D., has been linked to Ionis Pharmaceuticals and Novo Nordisk.
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Neuron Discovered That Suppresses Eating May Lead to Effective Diet Drugs - SciTechDaily
Are High-Fat Diets As Healthy As They’re Cracked Up to Be? – Yahoo Lifestyle
Celebrities like Kourtney Kardashian, Halle Berry, and Vanessa Hudgens have all touted a high-fat diet as their secret to losing weight and staying fit, all without feeling hungry or deprived. In fact, many of the most popular diets of the past decade included high amounts of fat: the ketogenic diet, Paleo, the Mediterannean diet, the carnivore diet, and the Bulletproof diet.
But it wasnt too long ago that fat had a bad rap. During the low-fat craze of the '80s and '90s, people looking to lose weight and improve their health opted for a low-fat diet. Then, the pendulum swung the other way. Now, low-carb, high-fat diets are trending for weight loss and better overall health.
RELATED: These Are the Diet Trends That Dominated the Last Decade
Thats probably partially because weve learned a lot about fat since the days of low-fat-everything. Back then, many thought eating fat equaled more body fat, explains Amanda Baker Lemein, R.D. Now, we understand that simply is not true. Instead, we know that if you eat more calories than you burn, you gain weight. And this can happen from overeating any macronutrient protein, carbs, or fat not just one alone.
But even if fat isnt bad for you, does it deserve its current super nutrient status? And is it even healthy to eat a high-fat diet long-term? Here, nutrition pros share everything you need to know.
Fat is the most energy-dense nutrient, containing 9 calories per gram compared to the 4 calories per gram found in carbohydrates or protein, explains Gabrielle Fundaro, Ph.D., a consultant for Renaissance Periodization. Fat is an essential nutrient, Fundaro says, meaning your body cant make it so you have to eat some of it.
While a low-fat diet can be healthy, not getting enough fat in your diet can cause health issues. Consuming too little fat can result in dry skin, decreased energy or satiety levels in between meals, decreased vitamin absorption for vitamins A, D, E and K, increased risk for depression and other mental or cognitive issues, and hormonal imbalances, Lindsay says.
So how much fat should you be eating? Healthy adults should aim to consume between 20 to 35% of their calories from dietary fats, says Victoria Lindsay, R.D. (So if youre eating 1,800 calories per day, that would mean eating between 40 and 70 grams of fat.) Of course, those are just general recommendations. How much fat you should eat is really an individual thing, Linsday emphasizes. And if youre on a true ketogenic diet, your fat intake could be at upwards of 70 percent of your total calories.
RELATED: Whats the Keto Diet? Everything You Need to Know
In a lot of ways, nutrition experts are enthusiastic about fats rise from its previous nutrient non grata status. I think it is a great thing that we are no longer afraid of fat, Lemein says. Fat is incredibly satiating, and because it delays gastric emptying (aka food leaving the stomach), it helps us stay fuller for longer. Plus, some of the most-nutrient rich foods are high in fat, like avocado, nuts, seeds, and fatty fish like salmon.
With fat bombs, Bulletproof coffee, and other high-fat snacks all over social media, its understandable that people get the impression that fat is better than other nutrients, or that certain types of fats are superfoods.
The truth? There are no superfoods, though there are some foods that are more nutrient-dense than others, Dr. Fundaro says. Theres some emerging research showing that certain, very specific types of fat might be beneficial (think: MCT oil). But Dr. Fundaro emphasizes that just because something shows potential benefits in a research setting doesnt mean its worth trying as an expensive supplement.
I find this to be unfortunate, because people may spend time, money, and energy on these biohacks that only add extra (and perhaps unneeded) energy to the diet by way of adding fat to their daily intake, Dr. Fundaro notes. In other words: Eating naturally-occurring fats in whole foods that you enjoy? Great. Adding fat to your diet in the form of supplements or eating high-fat foods you wouldnt normally eat? Totally unnecessary. Especially if you just end up eating unnecessary calories youre not enjoying in the name of health.
Plus, the pendulum effect is real. While Im glad that fat is no longer being vilified, its a tradeoff, as carbs are now the trendy nutrient to avoid, Lindsay points out. But eating carbs is actually better for your health long-term than not eating them.
It seems as though the pendulum has swung a bit too far in the opposite direction, Lindsay adds. While keto can be a healthy way to eat, it does carry some worrying side-effects just like any extreme diet.
Whats more, we dont know much about the long-term effects of a super high-fat diet. While diets like keto can result in weight loss, its usually due to an overall calorie restriction rather than abstinence from or addition of certain foods. But people dont see that: all they see is results, Linsday says. What they dont see is one or two years down the road when the person experiencing the dramatic weight loss has gained all if not more of it back. Nor do they see some of the long-term effects of eating in such a restrictive way, mainly because we often dont know what those are yet. For some diets and eating patterns, only time will tell.
Whether you eat high-fat, low-fat, or somewhere in between, its important to know that the types of fat you eat matter. Some types are associated with better health, while others are not.
Saturated fat isnt inherently unhealthy, but high intakes are associated with increased risk of cardiovascular disease, Dr. Fundaro says. Animal fats (with the exception of fish oils) are common sources of saturated fats. Coconut oil is high in saturated fat, as well. Replacing saturated fat with polyunsaturated fat may reduce the risk of cardiovascular disease. Theres some debate over whether saturated fat really is detrimental to health or not, but for now, its recommended that saturated fat make up no more than 10% of your daily calories.
Monounsaturated is a beneficial fat that is associated with improved cardiovascular health, says Allison Knott, MS, RDN, CSSD. Its found in vegetable oils (like olive and canola oil) and other common foods like peanuts, avocado, and various nuts and seeds.
These are generally found in plant foods and fish, and there are several different types. The most notable are:
You probably know that these are the fats you want to stay away from, as even small amounts can increase your risk of cardiovascular disease, Linsday says. Thankfully, artificial trans fats are being phased out by food manufacturers. They usually come in the form of partially hydrogenated oils in fast food or pre-packaged snack and convenience foods. Trans fats are also naturally found in beef fat and dairy fat in very small amounts.
When figuring out how much fat you should include in your diet, it can be helpful to know that based on the latest research, low-carb and low-fat diets perform equally in terms of weight loss and improving metabolic health. So how do you choose a fat intake that makes sense for you?
The most healthful diets include a variety of foods that an individual enjoys in amounts that promote health and well-being, Dr. Fundaro says. The Mediterranean Diet, DASH Diet, and Flexitarian diets are all often rated as the best diets by U.S. News and World Report, she points out. None of them are particularly low in carbohydrates or fat, nor do they recommend cutting out any food groups. They are simply easy to follow, nutrient-dense, appropriate to use for weight loss (within a caloric deficit), and generally cardioprotective, she adds.
On the other hand, low-fat and low-carb diets can be really hard to follow, which means lasting weight loss is not likely if thats your goal. For that reason, its best to choose a diet that you can envision yourself continuing with long-term. Even if youre not concerned with your weight, Dr. Fundaro says getting a healthy variety in your diet is key. That means eating a wide array of plants (veggies, fruits, and whole grains) while limiting processed foods, saturated fats, trans fats, added sugars, and sodium.
Despite the popularity of high-fat diets, low-fat foods are still widely available in grocery stores. Whether or not you should choose them, Lindsay says, is mostly up to personal preference. I know plenty of people who, for example, prefer 2% or skim milk in their cereal versus whole milk, and Id never disapprove of that choice if thats what they like. Some people are also advised by their doctor to use low-fat products because of a health condition, such as heart disease.
The issue for me is when people choose low-fat foods because theyre too afraid to choose the full-fat counterpart for fear of eating too many calories or eating something they feel might be too unhealthy, Lindsay explains. This may indicate an issue like orthorexia, or another non-sustainable eating pattern.
Lindsay also recommends avoiding processed low-fat snack foods like crackers, chips, and cookies. The problem with these products is that as a substitute for fat, manufacturers will usually compensate with added salt and/or sugar, not to mention that the taste is usually inferior to the full-fat version anyway. If you want to have one of these foods, in most cases, you might as well go for the real thing.
At the end of the day, its about finding balance in your day-to-day food choices and in your overall approach to eating.
For example, if someone is consuming a breakfast that includes nuts (aka another fat source), maybe a low-fat yogurt is the right choice for them to balance out their overall intake, Lemein says. But, if they are just eating fruit and yogurt, the extra fat might add some staying power to the meal and help keep them fuller for longer, she adds.
As a dietitian, what Id love to see is this: balance, Lindsay says. The most nutritious diets are diverse. Have your carbs, have your protein, and yes, have your fat, but keep it balanced by eating a variety of foods.
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Are High-Fat Diets As Healthy As They're Cracked Up to Be? - Yahoo Lifestyle
What you need to know about fad diets – The Cambridge News
What is a fad diet? How do you define it? What are the characteristics? A fad diet is a weight loss plan or diet aide that promises dramatic results in a short period of time. Often developed by celebrities or medical professionals who call themselves weight loss gurus, these may result in short-term weight loss but typically do not result in long-term weight loss. Fad means short-lived (followed by the word fade) and may be dangerous to your health.
Topping the list of most popular fad diets include: low carb, high protein diet, high fat diet (Keto), low fat and very low fat diets, unlimited quantities of certain foods diet, raw foods diet, and the gluten-free diet.
Why dont they last? Many fad diets do work for a short time. By eliminating food groups, we are paying more attention to food. Much of the weight loss, however, is from water weight and lean tissue, not fat. Most folks are unable to keep up with the demands of the diet, and consequently, tend to regain the weight that they initially lost. Dieting can be draining physically, emotionally, and financially.
How to recognize fad diets? News flash: if it sounds too good to be true, it probably is! Many make rapid weight loss claims (10 pound loss per week), allow for unlimited quantities of certain foods (i.e., cabbage soup diet), recommend specific food combinations and rigid menus, and are promoted as a cure-all and use testimonials (i.e., celebrities, before and after photos, etc.).
Fad diets are so popular because: 1) People are interested in rapid weight loss; 2) Many of them do work for a short amount of time; and 3) By eliminating whole food groups, we end up consuming fewer calories.
What are problems with fad diets? 1) Diets are very limited, not meeting bodys basic needs lacking essential nutrients (such as vitamins A, E, D, B, calcium, iron, potassium, magnesium, and fiber). 2) Dieting messes up our hunger signals, making it difficult to recognize our bodies internal cues. This may lead to preoccupation with food, increased cravings, or inability to focus. Other problems include: fad diets are not palatable (i.e., low fat diet), inflexible, not allowing for deviation from the plan. Lets face it, how much bacon can we really eat? Some may be dangerous to our health, for example, the raw foods diet encourages intake of raw meat and seafood, increasing our risk for foodborne illness. Also, consider that a high protein diet may raise blood uric acid levels, which can adversely affect bone tissue, depleting the body of calcium via urine. Diets are expensive, averaging $33 billion per year, for example, the HCG diet will cost you $800/month. Much of the initial weight loss comes from water weight (and lean body mass), not fat loss. Also, diets tend to slow metabolism! (via consuming fewer calories overall).
How should you diet? Diets form the basis of our everyday food choices. We need less emphasis on diet, more on lifestyle habits. Rather than focusing on losing weight, focus on being healthy to improve overall feeling of wellness. Some of the best approaches include the USDAs My Plate emphasizes balance and variety! Also DASH diet (supported by the National Heart, Lung, and Blood Institute) has been shown to improve blood pressure, rich in magnesium, potassium, calcium, and fiber and low in sodium and fat, cholesterol and sugar. A healthy weight loss translates into a loss of lb to 1 lb per week. The optimal diet for weight loss will maximize loss of body fat while minimizing loss of lean body mass; it will also promote satiety (feeling of fullness), reduce our risk of chronic disease, and be convenient, palatable, and inexpensive.
What foods should we focus on? Increase intake of fruits, vegetables (high in antioxidants!), and whole grains, low-fat dairy products; decrease intake of prepackaged processed foods, sodium, fats and added sugars. Boost intake of heart-healthy fats including nuts, avocado, olive & canola oil, and fatty fish. Also, water is essential for weight loss for abating hunger and boosting metabolism (note: exercise is still the #1 way to increase metabolism).
How do I lose weight?
Dont take diet pills, including over-the-counter pills. These are expensive and will not produce long-term weight loss.
Focus on making healthy lifestyle changes. Eating a variety of foods to ensure that you get all your daily nutrients. Examples: eating breakfast, not skipping meals, drinking less soda or juice (more water!), watching portion sizes, reading food labels, increasing physical activity, and incorporating nutritious foods into your diet with less fat, sugar, and alcohol.
Recognize that it takes hard work. A pound of fat = 3,500 calories. Create a daily calorie deficit coupled with moving more to create 500 kcal deficit per day. Calories do count.
Be mindful. Focus on small changes. Drink one less soda per day, switch from whole milk to 2% milk, and consider mixing cereals and pasta, rice, incorporating more whole grains with less refined sugars.
Focus on more than just the number on the scale. How is your clothing fitting? Success is measured by multiple non-scale victories that are important to recognize and acknowledge.
Resources for Consumers:
UW Health website (www.uwhealth.org) Schedule an appt with a UW Health Dietitian
Choosemyplate.gov
Consider healthy diets such as Mediterranean/DASH diet and Weight Watchers
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What you need to know about fad diets - The Cambridge News
Diet Demand: What is the Sirtfood Diet and How Does It Affect Weight Loss? – Yahoo Finance
Honolulu, HI, Jan. 16, 2020 (GLOBE NEWSWIRE) -- The Sirtfood Diet is growing in popularity, but does it really work for weight loss? Sirtuins are defined as a cluster of proteins that play a vital role in cellular health and regulate various body functions. These sirtuins may also play a major role in regulating the metabolism, fat burning, increasing muscle mass and reducing inflammation. According to sirtfood diet enthusiasts, certain whole foods contain sirtfood activators that increase these proteins in the body. A short list of popular sirtfoods includes:
One major reason the sirtfood diet has exploded in popularity is due to its allowance of dark chocolate and red wine, as both items are considered sirtfoods. The claim is that by focusing on these foods, rapid weight loss will follow without decreases in muscle mass. A sirtfood dieter will begin their first week drinking green juice made of matcha green tea, lemon juice, parsley, celery, a green apple and arugula three times per week. After the first week, sirtfood dieters return to eating three meals per day made only with sirtfoods and will continue to incorporate these foods throughout the remainder of the diet.
Does the Sirtfood Diet Actually Work?
There seems to be a growing number of celebrities and notable figures whove touted the sirtfood diet for their recent weight loss success. However, consumers must keep in mind that celebrities often have access to professional support when it comes to what they consume and any additional exercise regimens. Additionally, studies on the efficacy of this diet are slim. Granted, most foods listed are healthy whole food options and calorie restrictions which are automatically connected to some weight loss. The majority of foods listed have anti-inflammatory properties, high amounts of antioxidants and nutrients which are of course, beneficial. Medical experts warn though, that while quick weight loss is possible on such a diet, a majority of that initial loss will be water weight. It may also be risky for those who engage in moderate to high physical activity.
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Diet Demand: What is the Sirtfood Diet and How Does It Affect Weight Loss? - Yahoo Finance
Intuitive Eating: The Not-Diet Diet for People Who Are Sick of Diets – VICE
Maybe you read the widely-shared opinion piece in the New York Times calling on women to smash the Wellness Industry. Maybe youve heard that were in the middle of a backlash against diet culture, or that the latest diet trend is not dieting.
Sounds pretty good, right?
That not-diet diet everyones talking about is intuitive eating, and its the current source of curiosity/obsession among health bloggers, Instagram fitspo accounts, and wellness news publications including, I guess, VICE? 2019 was a big year for intuitive eating, with trend stories appearing everywhere from NPR to the Cut in the last several months.
This way of eating may be newly resonant, but its not newthe philosophy was introduced by dietitians Evelyn Tribole and Elyse Resch in their 1995 book book Intuitive Eating: A Revolutionary Program That Works.
Its not a fad, and thats the difference, said Lisa Sasson, a clinical professor of nutrition at NYU Steinhardt. I teach it in all my classes.
Put simply, intuitive eating is intended to eliminate the guilt associated with food and the binary of foods as good or bad. Its more of a psychological attitude; its not about counting calories or eat this, dont eat that, Sasson continued. Intuitive eating doesnt exult any of-the-moment superfoods; theres no obsessive nutrition label reading.
It is, technically, eat-whatever-you-want, but theres a bit of public misperception around that: Registered Dietitian Anne Mauney, who also uses Instagram to promote an IE lifestyle (@fannetasticfood), said that even though youre not paying attention to calories when eating intuitively, you are being conscious of how hungry or full you are. Theres a focus on how foods make you feel, and an emphasis on mindfulness. That means eating slowly, putting down the fork periodically, checking in after a few minutes to see if youre still hungry, and not continuing to eat just because theres still food on your plate.
The idea is that the longer you stick to these lifestyle changes, the more youre in control. You respect your own bodys signals, Sasson explained.
Its also not a weight loss plan, no matter what you mightve read. If you Google intuitive eating, intuitive eating for weight loss comes up pretty early, Mauney said. Its frustrating, because Ive seen a lot of people marketing intuitive eating for weight loss, which is not at all what its about. If youre really focused on weight loss, its going to be almost impossible to be an intuitive eater.
One of Sassons classes is called Nutrition Through the Life Cycle, and she said were a nation with an eating disorder, behavior that begins when were kids. Children rely on hormones that tell them when theyre full or hungry; they know to eat and when not to. Its parents who make them finish food even if theyre full so they can, say, watch TV or go play. When food becomes more than foodwhen broccoli is a requirement or cookies become a rewardthats when people get out of touch with their own body cues. And that internalized message can follow you your whole life, leading to moderate body dissatisfaction or an all out eating disorder.
Thats not the only thing making it tough to practice. Theres also the fact that the moment we live in is that it isnt built to make eating well, quite so intuitive.
We live in a 24/7 world of food advertisements on the television, on the radio, on Facebook and Twitter, said UCLAs Dana Hunnes, a senior dietitian at the Ronald Reagan Medical Center.
You know, I was at Macys, the department store, a few weeks ago, Sasson said. Every floor had food. You could smell the aroma as youre going through womens shoes, or womens dresses. There was an eating opportunity on every floor.
In a world where SUVs come outfitted with XL cupholders and snacks are engineered to make us crave more and more of them, eating well can be a challenge. When youre constantly being bombarded by billboards plastered with 20-foot-tall burgers; scrolling Twitter during, say, a week-long media craze over a certain fast-food fried chicken sandwich; or looking at the umpteenth grain bowl or smoothie bowl in your Instagram feed, it can be difficult to parse what you want from what you think you want. Hunnes said all that subliminal messaging can dampen or influence our own intuitive thinking, which makes it easy to see why some are skeptical about the IE lifestyle.
So what do you do about it? In short: If you think you want it, eat it. There's no judgement either way, this is all just information, said Molly Bahr, whos both a licensed mental health counselor and an intuitive eating Instagrammer. This can be a helpful reframe each time we think we mess up with intuitive eating ... there is no messing up, it's just information. How else will we learn our natural body cues, what we find satisfying, or what feels good in our bodies? It's all an experiment, and we're gathering data.
Intuitive eating isnt a get-fit-quick schemedietitians will tell you its more of a yearslong and in fact lifelong undertaking. Bahr said its a way of eating and living meant for anyone whos tired of going on diets but not getting the long-term results they expected or hoped for. One of the things she liked about it is that it can truly be tailored to anyoneespecially with the help of a dietitianregardless of their relationship with food.
Someone with anorexia or who has dieted for a long time may not be able to detect their hunger or fullness cues yet, but they can start with other principles like rejecting the diet mentality and work with a dietitian on how to navigate the hunger and fullness piece until the cues get back on line, she explained. Keep in mind, this process can take months and years. No one is expected to get a handle of all 10 principles in 12 weeksthat's sort of a lingering diet mentality.
If youre wondering where to start, or are interested in learning how you can adopt some of the principles in your own life, we asked them to demystify the process and tell us what the intuitive eating-curious need to know.
Bahr recommends reading the books Intuitive Eating, Health At Every Size, The Body Is Not An Apology, and Just Eat It. And she has an array of podcast recommendations: Dietitians Unplugged; Love, Food; Food Psych, Dont Salt My Game.
If that sounds like a lot of reading and listening and youre ready to get going right now, she also laid out the 10 principles of intuitive eating (which you can read more in-depth descriptions of here):
1. Reject the diet mentalityLearn about diet culture and why diets don't work, set aside weight loss goals, and let go of dieting behaviors to get out of our heads and into our bodies.
2. Honor your hungerEat consistently, throughout the day, including when you notice gentle signs of hunger.
3. Make peace with foodGive yourself unconditional permission to eat all foods (excepting those you cant because of medical conditions, of course).
4. Challenge the food policeSay no to the food rules diet culture has taught us about what, how much, how often, and when to eat.
5. Feel your fullnessListen for the signs you're no longer hungry; notice the signals telling you when you're comfortably full.
6. Discover the satisfaction factorEat what you really want to eat. No more food swaps for zucchini when youre feeling pasta.
7. Cope with your feelings without using foodSeek out and learn additional ways to deal with emotions and practice self compassion.
8. Respect your bodySimply put? Treat and talk to your body with respect.
9. Joyful movement: feel the differenceEngage in activities you find enjoyable, and notice what you like about it (better sleep, more energy).
10. Honor your health with gentle nutritionEat a variety of foods and notice how they feel in your body.
Note that these are guidelines, not rules. You dont have to (and truly, wont be able to) do all 10 right away. And, Bahr said, theres no such thing as failure or messing up here; there are wins, and theres learning. You dont have to go in orderalthough principle 10 is listed last for a reason. If we jump into nutrition too soon, we can quickly turn it into another diet, Bahr said.
What happens over time as we start to feed ourselves consistently with food we want, learn our hunger and fullness cues, notice how foods feel in our body, stop constantly trying to lose weight, and cope with our emotions in healthy ways we will naturally begin to crave a variety of foodsincluding nutrient dense foodswithout actually trying to focus on the 10th principle.
If you came to intuitive eating by way of Instagram, you might believe the movement is for a certain type of (thin, privileged) person. (Take a scroll through a few lists of intuitive eating Instagrammers to follow, and youre going to see a lot of white women with incredibly toned upper arms who incorrectly overextend intuitive eating into being a weight loss method.)
Social media absolutely creates a distorted sense of reality and unrealistic expectations, Bahr said. The people she chooses to follow dont center their body on their accounts. In other words, Bahr said, Their body is not their business card.
She recommended digging into your personal biases when it comes to intuitive eating online. Do most of the people you follow look like you or your ideal self?
It may be a signal to diversify who you follow. Look for accounts in different sizes, colors, abilities, and lifestyles.
I know how hard it is in the beginning to wrap our minds around this, but there are no rules in intuitive eating, Bahr said. (Unless, of course, eating something would be fatal.) As humans, we want what we can't have; a lot of people discover they don't actually like the foods they've been avoiding. It took me a few boxes of Pop Tart flavors to realize I actually don't even like them and I haven't looked back since.
Bahr described giving yourself this permission to eat as working through a habituation phasethink, for example, about how excited you are when you get a new phone, outfit, or even a new relationship. Now think about how you feel about these items a year later. The overexcitement fades.
This is where mindfulness comes in: eating slower, chewing, and really being aware of your food. Mauney tells clients to actually pay attention, put it on a nice plate, really sit downno distractionsand enjoy that food. You might realize that half of a cupcake is enough to leave you feeling satisfied, loosening the grip and diminishing the allure that certain foods once held over you.
When you assign a negative trait to a food, you give it power, Sasson said. If you worked in an ice cream shop, and every day you could have two scoops of ice cream, ice cream would not be a big deal anymore. Its denial and deprivation that can lead to obsession.
Its not uncommon to eat emotionally, whether that emotion is loneliness, or sadness, or good old-fashioned boredom. Sassons recommendation was to try and find something else you can do when youre stressed or overwhelmed, and to learn ways to deal that arent foodwhich can provide temporary comfort, sure, but doesnt deal with the real issue.
Bahr said that in the same way cravings and binge-y behaviors will become less frequent the longer you eat intuitively, external factors will begin to influence your food and drink choices less over time. Just as we can trust our body to breathe, tell us when we need to go to the bathroom, or go to sleep, we can learn to trust our hunger and fullness cues while also aiming for satisfaction in our eating experience.
Bahr said to throw out the scale (the one for weighing you, and the one for weighing food) and to delete your food tracking app and other fitness trackers, along with old transformation pictures. She recommends unfollowing accounts that promote diet culture, and instead following actual intuitive eating or healthy-at-any-size accounts.
But, again? Dont feel like you have to do all of that right now.
I havent met anyone thats completed all these things in one day, Bahr said. This takes time. We let go when were ready.
No one is a perfect intuitive eater. Im not sure we can ever 100 percent get rid of those [negative] thoughts, Bahr said. Just know that we dont have to believe all our thoughts. They arent always helpful. They arent orders. And we dont have to listen to them.
It might be really, really hard. This is not a way of eating or living that meshes with our get-it-now culture. But over time, you might feel better. Over time, you might be able to find the joy in eating again.
And whos to say something that gives you psychological joy isnt as important as something thats good for your body? Sasson asked. Start to learn the pleasure that food can bring.
What is intuitive eating? Its really that youre an expert on your own body, Sasson said.
But once again: Its a diet only in the way of eating sense, not in the do this to drop 10 pounds fast sense. Its being co-opted by diet culture and sold as the new weight-loss program, Bahr said, so its confusing to know what's current and who to listen to. Its possible to lose weight with the program; others gain weight.
For anyone who gains weight after intuitively eating, seeing [a] thin, fit celebrity talking about it and praising it may send them mixed signals and may damage their self-esteem, said UCLAs Hunnes. And that could lead an IE newbie to return to the disordered patterns theyre familiar with.
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Dr. Oz Says We Should Cancel Breakfast, But Mark Wahlberg Thinks It’s a Terrible Idea – GoodHousekeeping.com
If Dr. Mehmet Oz had his way, we'd all simply be eating brunch every single day of the week. In fact, the 59-year-old cardiothoracic surgeon feels so strongly about skipping breakfast, he says he's making it his mission in 2020 to make everyone aware of possible dietary pitfalls associated with the meal.
Dr. Oz first dropped his controversial comments over the weekend while promoting his new program, System 20, at an event in NYC. "I think for 2020, the first thing I'm going to do is ban breakfast I don't think we need to eat breakfast, that's an advertising ploy," he told TMZ.
Since then, he's also shared his hot take on Fox & Friends.
Oz explained that he arrived at his decision after exploring the long-term weight loss benefits of intermittent fasting. Rather than obsessing over eating before heading out to work, he advises that we should "cancel" (yes, cancel!) breakfast and enjoy a larger meal closer to noon. "If you're intermittent fasting and you hadn't had a late dinner, [you] won't [feel hungry] until midway through the morning," he said. "Have brunch every day of the week!"
But what about all of the advice we've heard on the contrary? And, more importantly, what if you feel genuinely hungry for breakfast when you wake up? Oz explained that it may be a result of initial food withdrawals, especially if you ate a snack right before bed the night before. "Because you had some simple carbohydrates, like a potato chip or french fries at 10 at night, that means your body's insulin is all whacked up," he said. "By the next morning [when] that withdrawal is happening, you're starving like a drug addict. You got to get your meds."
Many people, fans of The Dr. Oz Show included, were surprised to hear Oz's rather strong take on a divisive topic. But none were as upset than actor and all-around fitness icon Mark Walhberg himself, who later told another TMZ reporter that he completely disagrees with Oz. "Listen, I don't care what Dr. Oz says, I gotta have my breakfast before I work out," said Wahlberg, who has previously shared details about his 3 a.m. workouts on social media. "That's my preference."
Dr. Oz's argument largely hinges on whether or not you've been fasting prior to breakfast. "I don't think you should eat breakfast until three to four hours after [you've] awaken," he shared while appearing on Fox & Friends, where he highlighted advice for those who are interested in trying intermittent fasting for the first time. Oz also mentioned a new landmark report published in The New England Journal of Medicine that suggested that fasting diets may help reduce the risk of cardiovascular disease over time, suggesting that intermittent fasting is healthy "even if you don't lose weight on it."
Since intermittent fasting is most often based on the 16:8 model, which means you're only allowed to eat meals during eight hours of the day, Dr. Oz's point about skipping breakfast may allow you to enjoy a later dinner. But if you're not restricting when you're choosing to eat, skipping breakfast may cause you to make poor decisions later in the day, says Charlie Seltzer, MD, a Philadelphia-based weight loss and fitness expert. "There's conflicting arguments, in some sense, as there has been research published suggesting that people who have breakfast may maintain a lower weight than those who don't," Seltzer says. "But the evidence is clear: If eating breakfast means you're also eating less throughout the day, then you should eat it. If you start eating breakfast and still are overeating at other meals, then you should consider skipping it."
But skipping breakfast can be somewhat harmful if you're active in the morning and need motivation to hit the gym before work. Seltzer says recent evidence suggests that training while fasting could end up decreasing the amount of muscle protein your body builds during a workout. One study published in the European Journal of Sport Science found that men who were fasting during muscle-training workouts weren't able to build muscle mass in the same manner as those who weren't fasting.
Just like there's a debate over whether or not breakfast is a must, health experts also have trouble defining what exactly a healthy breakfast looks like. "It really depends; everyone is different. If someone eats a donut every morning, and they're regularly doing well on blood tests and they're lean, then that's what they should be doing," Seltzer says. "But a good rule of thumb is that if you're going to eat breakfast, there should be some protein in it."
Seltzer's go-to is skim-milk greek yogurt, which can provide you just as much protein as hard boiled eggs or almonds in larger quantities. "Three Dannon Light and Fit yogurts contain 240 calories and 36g of protein, whereas a handful of almonds contains the same amount of calories... but makes you hungry faster due to its serving size," Seltzer shares. Regardless of which pantry staple you choose to incorporate into your routine or if you decide to skip breakfast altogether be sure to take note of what your body is telling you before making any rash decisions.
After hearing what the actor had to say, Dr. Oz challenged Wahlberg to a bit of competition, insinuating he would have better results at the gym since he follows intermittent fasting.
Wahlberg has since posted a video on Instagram, calling out Oz, saying the doctor would "need in a defibrillator once I'm done with you."
I guess we'll just have to wait and see who reigns supreme. Maybe then we'll know if breakfast should really be canceled.
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Weight Loss Drug Belviq Tied To Possible Increased Risk Of Cancer, FDA Says – CBS Baltimore
(CNN) The US Food and Drug Administration warns that prescription weight loss medicine Belviq might be associated with an increased risk of cancer.
The findings were the result of a clinical trial assessing the safety of the drugs Belviq and Belviq RX, or lorcaserin, the FDA announced on Tuesday.
At this time, the cause of the cancer is uncertain, and we cannot conclude that lorcaserin contributes to the cancer risk. However, we wanted to make the public aware of this potential risk. We are continuing to evaluate the clinical trial results and will communicate our final conclusions and recommendations when we have completed our review, the FDA said in its announcement.
The agency went on to note that health care professionals should consider if the benefits of taking lorcaserin exceed the potential risks for a patient and that patients currently taking the drug should talk to their doctors about the potential increased risk of cancer.
The drug manufacturer, Eisai Inc., responded to the FDAs announcement in a written statement on Wednesday.
Patient safety is Eisais priority and we will continue to work closely with the FDA to evaluate the clinical trial results, the statement said. We recommend patients speak directly with their health care professional in order to make the best decision about their medical treatment. As indicated in the FDAs communication, at this time, the FDA and Eisai cannot conclude that BELVIQ increases the risk of cancer.
Lorcaserin, an oral medication, was approved by the FDA in 2012 and made available by prescription the year following to help weight loss in adults who are obese or are overweight and have weight-related medical problems, according to the FDA.
Lorcaserin available as Belviq, which is a twice-daily tablet, and Belviq XR, which is an extended-release once-daily tablet works by increasing feelings of fullness so that you eat less food.
The FDA said in its announcement that, when approving lorcaserin, the agency required the drug manufacturer, Eisai Inc., to conduct a randomized, double-blind, placebo-controlled clinical trial to evaluate the risk of heart-related problems. In the trial, conducted in about 12,000 participants over five years, more patients taking lorcaserin were diagnosed with cancer compared to patients taking a placebo, which was an inactive treatment.
Our evaluation of this potential signal is ongoing, and at this time it is uncertain if lorcaserin increases the risk of cancer, the FDA said.
Weight loss drugs approved for long-term use include orlistat (brand name Xenical), lorcaserin (Belviq) and liraglutide (Saxenda) as well as the combination drugs naltrexone-bupropion (Contrave) and phentermine-topiramate (Qsymia).
In one recent study, these drugs helped overweight or obese people lose at least 5% of their body weight at the end of a year thats at least 10 pounds if you weigh 200 compared with a placebo. Qsymia and Saxenda were associated with the highest odds of achieving that amount of weight loss.
For many, losing 5% to 10% of your body weight is associated with improved blood pressure, triglycerides and blood sugar, factors that lower the risk for heart disease and diabetes.
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Weight Loss Drug Belviq Tied To Possible Increased Risk Of Cancer, FDA Says - CBS Baltimore
Only Half! Adele Has Shed And Lost Weight For Her Son – The Digital Weekly
The former personal trainer of Adele has highlighted the weight loss of seven stones of the superstar, which shows that she achieved her slimming physique by following a strict diet of green juice and 1,000 calories per day.
The Brazilian body wizard, Camila Goodis, gave a unique insight into the exhausting regime, which saw the 31-year-old musician shed Lorenas pounds on Thursday, explaining that he took a strict approach to food and stuck to daily practice. They are.
The Los Angeles-based personal trainer reported that Adeles body changes are primarily due to a reduction in their calorie intake, which reduces the recommended daily amount for women by 2,000 calories. Goodis said she is hosting the Lorraine Kelly show.
This is a proper diet to lose weight. The first week is intense, green juice, and only 1,000 calories. She doesnt look fragile; she looks fantastic. The coach, who describes himself as a Brazilian body wizard, was introduced to Adele through Robbie Williams wife, Ida, and even a joint in the former Take The Star mansion in Los Angeles. Training also is given.
The singer has used fans with her weight loss, which she revealed for the first time at Christmas and appeared during a holiday in Anguilla with Harry Styles earlier this month. It is believed that the Rolling in Deep kicker changed his physique after a diet review, but was inspired to do so for his seven-year-old son, Angelo.
A source told People earlier this week: He reached a point where he didnt like it very much. I knew I would have to change something because I wanted to be the healthiest mother. All his focus during the weight loss journey has been on how he can stay healthy and how to best treat his body. He never tried to lose weight. Lexi met the singer at Blanchards Restaurant and Beach Shack in Anguilla.
She said: He said he lost something like 100 pounds, and its a very crazy and positive experience. She looked delighted, and she looked amazing. The teenager said the singers weight was evident because she was about to eat it.
Lexi said that Adele didnt want to take a picture with her because Angelo was present at the time, but he took Harry to the restaurant to chat with his group of friends. She revealed that she and a group of Pulse talked to British stars for about 15 minutes and talked about university life and their plans.
In October, Adele joked that she used to cry, but now she was sweating in an Instagram post, as details of her overheating regime were revealed. It is believed that his most significant change was the result of the Pilates reformer, the use of weights in the gym, the reduction of sugar, and the follow-up of The Only Food. The regime focuses on plant foods, such as bananas and buckwheat, which help suppress appetite and activate the skin genes of the body.
The creators of the diet claim that following the Sirtfood diet will cause rapid weight loss, maintaining all muscle mass, and protecting it from chronic diseases. Diet supporters go through two diet cycles that last three weeks, following specific recipes and plans, and then they are encouraged to include more and more fair foods in their meals.
However, Healthline reports that although a low-calorie diet can begin to lose weight, it has little to do with long-term health effects. Speaking in June, the sources claimed that Adeles new training regime gave her vocal talent a new life opportunity after her separation from former husband Simon Konki, with whom son Angelo shares.
Adele confirmed his separation from Simon in April 2019 and filed for divorce in September. The vocal power and Simon began dating in 2011 and welcomed their son the following year, before getting married four years later. In 2015, Adele revealed that she had changed to a healthier lifestyle to keep her voice in good condition.
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Only Half! Adele Has Shed And Lost Weight For Her Son - The Digital Weekly
Chad Tackett, Founder of Committed 100, Discusses the 5 Worst Condiments for Weight Loss – Yahoo Finance
HAPPY VALLEY, OR / ACCESSWIRE / January 16, 2020 / Condiments may seem insignificant when it comes to diet. A chicken breast slathered in barbecue sauce is still a chicken breast, right? According to nutrition expert Chad Tackett, founder of Committed 100, unfortunately, that isn't always the case. Condiments, he says, can pack a bigger caloric punch than you might realize and could derail your healthy intentions.
5 Worst Condiments for Fat Loss
1. Ketchup
Ketchup is one of America's most beloved condiments, found on everything from fries and burgers to steak and eggs. But the sweet tomato paste is loaded with sugar and high fructose corn syrup and high in calories. What makes ketchup particularly bad is that most of us eat much more than the recommended serving size of two tablespoons, meaning instead of consuming about 20 calories with a splash of ketchup, we're more likely consuming 60. Instead of ketchup, consider salsa for a low-calorie, low-sugar alternative.
2. Ranch dressing
Salads are a health food staple. But dressings can turn an otherwise healthy salad into a high-calorie, high-sugar, and high-fat dish quickly. Ranch is one of the most popular and least healthy dressings out there, with about 180 calories, 20 grams of fat, and 245 mg of sodium per two-tablespoon serving. Consider trying alternatives like a low-calorie vinaigrette or tzatziki, or make your own Ranch at home with greek yogurt, vinegar, and dill.
3. Margarine
There's a widespread misconception that margarine is better than butter because it's lower in fat and calories. However, it is higher in trans-fat, which can contribute to heart disease, skin problems, hormonal issues, and other ailments. In baking, you can substitute butter or margarine with applesauce. Otherwise, consider hummus or roasted garlic which adds flavor and health benefits.
4. Mayonnaise
Similar to margarine, mayonnaise contains loads of trans fats. It's also high in calories, salt, and fat, with about 120, 290 mg, and 10 grams of each, respectively, per serving. Make your own mayo at home using eggs, olive oil, lemon juice, and vinegar, Chad Tackett suggests. He adds you can also incorporate sun-dried tomatoes, Dijon mustard, garlic, hot sauce, curry powder, or hummus.
5. BBQ sauce
A summertime staple, barbecue sauce is unfortunately very unhealthy and high in calories, sugar, and sodium as well. Depending on the variety, BBQ sauce can have 60 to 120 calories per serving. Instead of slathering your grilled meats with this sweet sauce, consider a dry rub and pepper, Chad Tackett suggests. Hummus is another alternative that can go well with burgers and sandwiches.
More on Chad Tackett
In the past 25 years since creating Committed 100, the world's first online weight loss program, Chad Tackett has helped people in over 100 countries, of various ages, sizes, and backgrounds, achieve their health and fitness goals. He endeavors to help people make healthy and sustainable lifestyle changes to live happier, healthier, and more fulfilling lives without giving up their favorite foods or suffering through boring workouts.
If you are ready to fundamentally change how you think about food for the long-term and "fix" your metabolism Click here to watch this free training by Chad Tackett at Committed 100.
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New Body-Sculpting Method Zaps Fat With Injected Ice Slurry – Medscape
Body sculpting by nonsurgical fat removal may become an even more common cosmetic procedure than it already is, thanks to an experimental technique that homes in on subcutaneous fat with an icy injectable slurry.
Researchers at Massachusetts General Hospital in Boston report promising results from studies in swine using a biocompatible mix of ice, saline, and glycol injected at adipose tissue sites for selective fat removal.
They report a gradual reduction in the thickness of fat tissue of as much as 54.5% (5.9%) at slurry-targeted sites compared with 2.6% (0.9%) at control sites injected with a melted slurry (P < .001). Moreover, they observed a dose-response effect, with fat loss correlating to the total volume of ice injected. No scarring or damage to surrounding tissue occurred.
The research was published online January 7 in Plastic and Reconstructive Surgery.
"Our data shows that the slurry is safe, selective for adipose tissue, and leads to long-lasting or permanent loss of adipose tissue and the amount of fat loss correlates with total slurry ice volume," write Lilit Garibyan, MD, PhD, a dermatologist at the hospital's Wellman Center for Photomedicine and an assistant professor of dermatology at Harvard Medical School, and colleagues. "Slurry injection can be done in office under local or no anesthesia and it will take seconds to inject. The effect also appears to be long lasting or permanent."
The researchers previously developed the topical cooling method of fat reduction known commercially as CoolSculpting, a procedure that takes almost an hour in the office.
They injected varying slurry mixes of 30 mL or 15 mL and 20% or 40% ice content into the subcutaneous fat of young female pigs aged 3 to 6 months and weighing 52 to 85 kg. Control animals received injections of melted slurry.
Animals were assessed before injection and monitored periodically with ultrasound imaging for as long as 8 weeks. The injections produced no systemic side effects or abnormalities in blood chemistry, including liver function and lipid profile, at day 3 and weeks 2, 4, and 8.
The greatest fat loss of almost 55% was seen in the 30 mL/40% group. In other groups treated with either 15mL of slurry with 40% ice content or 30 mL of slurry with 20% ice content, fat thickness reduction was less: 25.3% compared with 16.7% (P < .05 and P < .001, respectively). Slurries with ice contents of 40% and 20% achieved average temperatures of 4.8C and 3.5C, respectively.
The corresponding volumes of fat loss in the three treatment groups were 2.6 cm3, 1.0 cm3, and 0.7 cm3.
"These dose-response studies highlight the importance of total ice volume for the biologic effect of the slurry, rather than the volume of slurry," the authors write. "Injected ice volume is the major determinant of how much adipose tissue will be lost."
Garibyan told Medscape Medical News that slurry recipients might initially feel quite cold at first as the subcutaneous temperature drops, "but at about plus 4C the nerves stop firing." Cooling could also have a collateral metabolic effect, she added, in that some studies have shown that cooling can convert white fat to brown fat, thereby increasing energy expenditure.
According to the investigators, ice slurry injection has the potential to become a "transformative and a minimally-invasive fat removal modality for body contouring." It has the capacity to target any volume of adipose tissue at any anatomic location.
Human trials are expected to get underway soon, Garibyan said.
Further studies in humans are clearly needed, Peter Henderson, MD, MBA, an assistant professor of plastic surgery at Icahn School of Medicine at Mount Sinai in New York City, stressed. "But there's a high likelihood that the same effect that was seen in pigs will be seen in humans. And if that proves to be true, then this technology has the potential to drastically change how excess and unwanted fat is treated throughout the body."
Henderson pointed to several concerns, however, including the longevity of the treatment effects and the long-term appearance of the fat and overlying skin as the surrounding fat increases or decreases with normal aging and weight fluctuations.
Another issue is how precise the location and extent of the fat reduction would be. "It is one thing to decrease fat in general, but especially in more nuanced parts of the body like the face and neck we would ideally like the amount of fat removed to be more specific, as an excessive or uneven fat removal could lead to an unsatisfactory result," said Henderson, who was not associated with the research.
Obesity medicine specialist Fatima Cody Stanford, MD, MPH, MPA, also of Massachusetts General but not involved in the study, also sounded a warning. "This study was done in swine so we have to be a bit cautious about translating the conclusion that this procedure will likely lead to long-term fat loss to humans," she told Medscape Medical News.
"And with cosmetic procedures, we don't often see sustained long-term results with anything that claims to remove fat tissue. Fat has memory it knows where it was, so you can take it away today but it knows it was there and it can grow back and sometimes even in areas where it hadn't been deposited before."
In addition, Stanford said, owing to the multifactorial complexities of obesogenesis and fat regulation in the human body, especially in the current obesogenic environment of the United States, significant long-term changes with this single treatment are not likely to occur. "I don't think this is the Holy Grail."
This research was supported by various funds. Lead author Garibyan and several study coauthors are inventors with patents owned by Massachusetts General Hospital and received part of a licensing fee. Coauthor Emilia Javorsky works for Arctic Fox Biomedical, which has licensed the patent for commercial development. Henderson and Stanford have disclosed no relevant financial relationships.
Plast Reconstr Surg. Published online January 7, 2020. Abstract
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