Search Weight Loss Topics:

Page 12«..11121314..2030..»

Home » Long Term Weight Loss » Page 12

The medical sensation of the decade is a set of drugs that help people slim down. With weekly injections, people can drop 15 percent to more than 22 percent of their body weight on average, often 40, 50 pounds or more. No safe medicine or any other weight-loss strategy except surgery has been so effective. Given that nearly 42 percent of Americans are obese, and thus vulnerable to diabetes, heart disease, stroke and various kinds of cancer, Wegovy, Zepbound and other so-called GLP-1 agonists come as a breakthrough. They offer a way to vastly improve public health not to mention quality of life among people who struggle to lose weight.

Surely, health insurers, including employers and Medicare, can find a way to pay for these extraordinary drugs. If they dont, only wealthy people will benefit while poorer Americans are more prone to obesity. And the opportunity to bring a large share of the population back to good health will be largely lost.

Doing this without drastically inflating the price of U.S. health care and straining public budgets will be hard. The monthly cost for the drugs is upward of $1,000. (Zepbound is $1,060 and Wegovy $1,350.) If Medicares drug-coverage program, Part D, were to cover Wegovy at the list price for all obese beneficiaries, it would cost more than the entire Part D budget and more than the total amount of excess health-care spending on obese Americans of all ages (estimated to be $260 billion in 2016), according to an analysis in the New England Journal of Medicine.

Part D pays for the drugs only to treat diabetes. The law bars the program from covering weight-loss medications, but Congress could easily remove this obstacle put in place at a time when overweight status was stigmatized as a personal failing, rather than reflective of deep-seated biological drives, and weight loss was considered only a cosmetic benefit.

The drugs stand to be alarmingly expensive for private insurers, too. If more than a tiny fraction of the people they cover use the drugs, the cost will drive up premiums for everyone. The injections are meant to be taken in perpetuity people who quit see much of the weight return which could translate into an enormous addition to Americas already world-beating health-care costs. Yet more and more employers are covering them, as most Americans want them to do.

Limiting demand would be a daunting challenge because almost half the U.S. population meets the Food and Drug Administration criteria for taking them: They have either a body mass index of at least 30 (obesity) or a BMI of 27 (overweight) and at least one weight-related ailment (diabetes, high blood pressure or high cholesterol, for example). Not everyone who qualifies will want the drugs, of course, and many who start taking them will quit. A recent study found that 68 percent of patients stop within a year of starting presumably, this is at least in part because of unpleasant gastrointestinal side effects. But demand is already so high, the drugmakers are having trouble keeping up.

This demand also keeps prices aloft. The medicines are priced at least 40 percent higher than what would be cost-effective, considering their benefits, according to the Institute for Clinical and Economic Review, a research organization. But the list prices arent immutable; theyre subject to negotiation. Private insurers strike deals with drugmakers to pay significantly less. And prices will fall as similar new drugs hit the market and, in years ahead, as generic versions of the drugs emerge. Note that Zepbound, which the FDA approved for weight loss this month, is cheaper than Wegovy, approved in 2021, even though studies suggest Zepbound may work a bit better.

Insurers can lower their prices by buying the medicines in bulk, guaranteeing drugmakers large markets. This strategy could also work for state Medicaid programs, only a limited number of which now pay for the drugs.

For Medicare specifically, Congress needs to grant Part D the authority to not only cover the medicines but also include them among the medicines for which the program can negotiate prices.

Even as prices fall, the federal government has a responsibility to support broader studies of the drugs long-term safety. It must also keep up other efforts to address obesity including by discouraging ultra-processed food and by encouraging greater physical activity (for example, by improving school lunches, food package labeling, and public spaces and pathways for exercise). The weight-loss drugs are not miracle cures. Many people cannot or do not want to tolerate them, and even patients who shed many pounds often remain obese or overweight. The medicines are one weapon in the obesity fight but one that, if broadly used, may be powerful enough to make a big difference.

Go here to read the rest:
Opinion | Wegovy, Zepbound and other weight-loss drugs should be ... - The Washington Post

Maintaining the success: Nine long-term weight loss secrets and strategies

Whether for health reasons or aesthetic ones, theyve finally managed to lose those unwanted pounds! While losing weight and getting to their desired health status is difficult, its just as hard to maintain their progress.

After most people lose their desired amount of pounds, their progress stagnates, and they return to their old lifestyle and eating habits. Unfortunately, this can result in regaining the pounds that they just lost and then some. If they want to keep this from happening and maintain their success in the long term, theyve come to the right place.

Dont stop exercising

When people have an end goal in mind, they find it fairly easy to work their tails off to reach their weight loss goals. Once they achieve their goal, its easy to take a few days off or reward themselves with more cheat days.

However, Its amazing how difficult it is to resume your exercise schedule after taking a few days or weeks off. Therefore, while its okay to slow down a bit and maybe add the occasional rest day, taking a prolonged amount of time off from exercising is a bad idea.

Stay accountable

While some people are disciplined enough on their own to lose weight and maintain their ideal weight, most people have more success when they dont do it alone. Having a friend, family member, or loved one to whom youre accountable can make a world of difference when it comes to losing weight and maintaining your success.

Thats why it may be beneficial to have an accountability partner that you check in with regularly to ensure youre maintaining your weight loss strategies and not getting stagnant.

Slightly increase the caloric intake

The way your body works is that you lose weight by having a caloric deficit. In other words, your body loses and works off more calories through exercise, sleep, and daily activities than it takes in through the food and drink you consume.

Therefore, once you reach your weight loss goals and youre in the maintenance stage, youll want to increase your caloric intake slightly. That way, your weight stays right where it is.

Have daily weigh-ins

Once you reach the maintenance stage, its important to have daily weigh-ins to ensure youre sticking to your weight loss game plan. If your weight fluctuates too much one way or the other, you can quickly make adjustments to get back on track.

Consider weight lifting

When people are working hard to lose weight, they typically focus on cardio, abs, and lots of movement. However, once theyre in the maintenance stage, adding a few days of weight training into the mix can be beneficial.

Lifting weights is a great way to regain some of the muscle you may have lost on your weight loss journey. Additionally, certain weight loss programs incorporate light cardio into the mix, making for a good, all-around workout.

Dont get down on yourself

Whether youre still in the weight loss period or the weight maintenance one, youre bound to have disappointments and setbacks. Maybe you gained a few pounds since your last weigh-in, or you gave yourself one too many cheat days.

Whatever it might be, setbacks are a part of life, and its important to deal with them constructively. Make sure you dont get down on yourself too much, as it could lead to a slippery slope of getting back into bad habits. Instead, pick your chin up, get back to your weight maintenance routine, and work even harder than you did before.

Water, water, water

No matter what stage you are in your weight loss journey, drinking lots of water is always important. Water helps keep you hydrated and energized throughout the day so that you have the energy you need to meal prep and work out. Water is also a natural filler, so loading up on water will help you eat less during meals.

Get plenty of sleep

In addition to being important for your mental health, sleep is also important for your physical well-being. While youre sleeping, your body is metabolizing food, burning calories, and building muscles. Each of these things is important for losing and maintaining weight, so you should strive for 7 and 9 hours of sleep each night.

Stress is a killer

When you feel stressed out, your body automatically releases cortisol to calm you down. While cortisol helps reduce your stress, it also contributes to fat and weight gain. Therefore, its important to find ways to keep from stressing out in the first place or to find destressing alternatives.

Last words

If you notice the scale creeping up again but havent changed anything about your routine, talk with your doctor about Dallas Wegovy pricing and if a prescription weight loss medication may be right for you. These once-weekly medications work to help you maintain a healthy weight by suppressing your appetite and increasing feelings of fullness.

Its important to find a sustainable system and stick to it to maintain your weight loss goals. Going from one diet to another, taking days off of working out, or throwing in random cheat days is a recipe for disaster.

The editorial unit

See the original post:
Maintaining the success: Nine long-term weight loss secrets and ... - The Upcoming

With the festive season sneaking up on us, so too is the Christmas feast with all the indulgent trimmings.

But if youre looking to shed a few kilos before the silly season, Brisbane dietitian Leanne Ward said there are three simple things you can implement into your life right now.

If you want to lose weight before Christmas, here are the things I recommend as an expert in healthy and sustainable fat loss, the mum-of-two said in her Instagram.

For more Lifestyle related news and videos check out Lifestyle >>

The three easy tips dont require you to spend any extra money.

To get started, Leanne suggested planning all your meals in advance.

What details most peoples fat loss attempts is making spur of the moment nutrition choices negatively influenced by friends, family or colleagues, she explained.

A huge win for fat loss is to meal prep if you can.

If not, know what your meals will be each day so youre not spending additional mental energy thinking about them and then just saying, Screw it, Ill eat whatever because Im tired or cant be bothered cooking.

The nutrition expert, otherwise known as The Fitness Dietitian on social media, said you should load up on enough protein and vegetables at each meal.

95 per cent of the population dont eat enough vegetables, she revealed.

Healthy adults should have more than five serves of veggies a day thats at least two-and-a-half cups of cooked vegetables or five cups of salad.

Ensure every meal has ideally 20 to 40g of protein in it.

Finally, Leanne suggested adding a buffer to your weekend.

To achieve fat loss you dont have to be perfect or 100 per cent clean with your choices, she said.

But if you have heavier food and alcohol on the weekends, you need to buffer this with lighter days during the week.

Too many people dont so they dont achieve the fat loss they desire.

Last month, Leanne revealed the secret to sustainable fat loss was to focus on what you can add in instead of what you should take out.

If the thought of doing something to help you lose weight long term makes you want to cry... STOP, she said.

If you cant see yourself doing something for at least 12 months such as creating a sustainable habit out of it theres no real point doing it as any weight you lose doing the strict behaviour means youre likely to re-gain it again the second you stop doing the behaviour.

The young me tried cutting things out 100 times before I realised that adding IN more filling whole foods and allowing the treats in smaller amounts instead of restricting then bingeing on them was the KEY to balance long term.

Leanne said she has been able to stick with a healthy diet and lifestyle for more than 10 years now without falling off the wagon.

Here are four things that helped her lose weight sustainably:

Often when I work with my coaching clients, I increase the amount of food volume theyre eating but lower the overall calories and their body goes from holding onto weight to kick starting fat loss without feeling starving, she said.

For more engaging lifestyle content, visit 7Life on Facebook.

Visit link:
Aussie dietitian on the three ways to lose weight before Christmas ... - 7NEWS

Weight loss can be tricky to navigate independently, so you should seek advice now. You want to know about Saxenda vs Mounjaro to determine which medication is best for your body.

Stop stressing and keep reading to go into your next doctors appointment armed with the knowledge that will lead to you making a healthy lifestyle change.

Dont just dive into one at random. Read on to learn more about Saxenda and Mounjaro.

Saxenda is the brand name for liraglutide. This is a medication initially developed for treating type 2 diabetes.

It was later found to induce weight loss. The FDA now approves it as a weight management drug.

Saxenda works by imitating a hormone called GLP-1 in the body. This hormone helps regulate appetite and decreases food intake, leading to weight loss.

Saxenda is administered through an injection. It is recommended for individuals with a body mass index (BMI) of 30 or higher. Those with a BMI of 27 or higher have at least one obesity-related condition.

Mounjaro is a combination medication that includes two drugs:

Phentermine is a stimulant that suppresses appetite. Topiramate is an anti-seizure medication with weight loss effects. Mounjaro is taken orally and comes in different doses, unlike Saxenda, which only has one dose.

Both Saxenda and Mounjaro are effective in aiding weight loss. The effectiveness of Saxenda lost an average of 4-5% of their body weight over a year. Those taking Mounjaro lost an average of 6-9%.

It should be noted that the effectiveness of these medications also depends on an individuals lifestyle and dietary habits. They are meant to be combined with a healthy diet and exercise for optimal results.

The weight loss effects of both medications may plateau after a certain period. Individuals may need to change their dosage or switch to a different medication.

As with any medication, there are potential side effects associated with Saxenda and Mounjaro. Common side effects of Saxenda include:

On the other hand, Mounjaro may cause :

There are also more severe side effects that may occur with both medications. It is essential to consult with a doctor before starting either medication. This is to discuss potential risks and determine if it is the right choice for an individual.

The cost of Saxenda and Mounjaro can vary depending on insurance coverage, dosage, and location. However, in general, Mounjaro tends to be more affordable than Saxenda.

Individuals should also consider the long-term costs of these medications. They may need to take them extended to maintain their weight loss results.

In some cases, insurance may not cover the cost of these medications. It makes them a significant financial investment for individuals.

When deciding between Saxenda and Mounjaro, there are several factors to consider beyond the primary considerations of effectiveness, side effects, and cost.

Its crucial to consider ones personal health history. Certain pre-existing conditions can interact negatively with these medications.

For instance, Saxenda may not be suitable for individuals with a history of pancreatic disease. Mounjaro may be less appropriate for people with a history of depression or mood disorders due to its potential to increase suicidal thoughts.

Lifestyle habits can significantly influence the effectiveness of these medications. These drugs are intended to be used with a healthy diet and regular exercise regimen.

Therefore, individuals who commit to these lifestyle modifications may see better results. Its also essential to consider any habits that may hinder weight loss, such as excessive alcohol consumption or smoking.

Individual preferences significantly determine the medicine one may opt for in their weight loss journey. These preferences are often shaped by personal comfort, ease of use, and the impact on daily life.

For instance, the method of administration can be a big factor. With Saxenda, its administered through injections, which may be off-putting for some people, particularly those with a fear of needles. On the other hand, Mounjaro is an oral medication, which may be perceived as more convenient and less invasive.

Both medications require a long-term commitment to maintain weight loss results. One must consider their readiness and willingness to take medication for an extended period and the associated costs. Individuals who prefer a more short-term solution may want to explore other weight loss options.

Long-term commitment to weight loss medications like Saxenda and Mounjaro extends beyond just the physical act of taking the medication. It entails a comprehensive shift in lifestyle and mindset. Patients should be prepared to incorporate regular exercise and a balanced, nutritious diet.

Finally, consulting with a healthcare professional before starting either medication is imperative. They can provide individualized advice based on your health history, lifestyle, and financial situation. This helps you make an informed decision.

Additionally, they can monitor your progress and make necessary changes to dosage or medication if needed.

If you are considering weight loss, choosing between Saxenda and Mounjaro is not a one-size-fits-all decision. Its about pairing the right solution with your unique health profile and lifestyle needs.

Remember, these medications are not magic bullets but tools that can bolster your weight loss journey when combined with consistent exercise and a balanced diet. Consultation with healthcare professionals is paramount in making this choice.

They can help you navigate each medications potential benefits, risks, and side effects. Ultimately, the best medication for you is the one that works harmoniously with your body and aligns with your personal health goals.

If you are looking for more medication options, check out these weight loss drugs. Your journey to a healthier you is personal, and your medication should be.

In conclusion, Saxenda vs Mounjaro are effective weight loss medications that work differently. Individuals should consult with a doctor to determine which medication best suits their specific needs and consider factors such as effectiveness, side effects, and cost before deciding. Whichever medication is chosen, it is essential to remember that weight loss requires dedication and lifestyle changes for long-term success.

So, working closely with a healthcare provider to develop a comprehensive plan for achieving and maintaining a healthy weight is vital. Remember that this document should be used as a reference only and not as medical advice.

For more helpful tips, check out the rest of our site today!

View original post here:
Saxenda vs Mounjaro: A Comprehensive Comparison of Weight ... - About Boulder

WASHINGTON The American Medical Association called on insurance companies, employers, and government programs to cover obesity treatments even as many remain reluctant to pay for them, fearing the costs of covering the drugs at a mass scale.

The large physicians lobbying group voted to pass a resolution at the associations interim meeting Monday saying it will urge all payers to ensure coverage parity for evidence-based treatment of obesity, including FDA- approved medications without exclusions or additional carve-outs.

Medicare is prohibited by law from covering weight loss treatments, and commercial coverage has historically been spotty, with many insurers viewing them as cosmetic rather than medical treatments. More recently, the emergence of GLP-1-based treatments like Novo Nordisks Wegovy and Eli Lillys Zepbound have raised concerns about cost. While the new drugs cause significant weight loss, they carry list prices of over $12,000 annually and are meant to be taken indefinitely. In addition, a vast number of people almost half the U.S. population are eligible for the medications.

Insurers have responded by instituting strict requirements for coverage, and some employers have even decided to completely stop covering obesity drugs.

But doctors say these actions are creating a patchwork of restrictions that are barring access for patients who need the medications to not only lose weight, but also address related health problems. Doctors point to data thats been recently released showing that Wegovy offers cardiovascular benefits in addition to weight loss.

The resolution by the AMA, one of the most influential medical groups in the U.S., adds further pressure on insurers. The association has increasingly taken stances pushing for changes in the way the health care community views obesity. Just a few months ago, it passed a policy asking doctors to de-emphasize the use of the body mass index to assess obesity and peoples health.

We have good drugs on the market. Patients deserve them. But today only rich people can get them, Ethan Lazarus, past president of the Obesity Medicine Association, said in support of the resolution at the meeting. Lazarus also does speaking events for Novo.

The AMA 10 years ago ratified a resolution officially calling obesity a disease. Weve come a long way in that timeframe, but we havent come a long way in getting patients the medications that they desperately need, Jonathan Leffert, a delegate of the American Association of Clinical Endocrinology and one of the authors of the 2013 resolution, said at the meeting.

However, not all the doctors in attendance supported the resolution during discussions.

Vanita Rahman, a clinic director at Barnard Medical Center in Washington, D.C., said rising obesity rates over the past decades are largely related to the increase in processed foods and other environmental factors. The drugs are effective at helping people lose weight, but theyre costly and people must remain on them indefinitely to maintain weight loss, she noted.

Rather than advocating for expensive drugs with limited and short-term benefits only, investing the same resources on diet and lifestyle could help far more Americans stay healthy for life, Rahman said.

Neal Barnard, an adjunct associate professor at the George Washington University School of Medicine, said he doesnt think insurers should be required to cover obesity treatments. If commercial plans or Medicare pays for them, that could ultimately lead to higher costs to all insured people, such as through higher plan premiums or higher taxes, he said.

The new drugs economic effects on the health system are under debate. Novo and Lilly have shown numerous studies conveying the message that their treatments would prevent people from developing complications like diabetes and heart disease and save costs in the long run. Independent researchers, however, have conducted analyses concluding that the drugs arent cost-effective, even at deep discounts.

The Institute for Clinical and Economic Review, a nonprofit organization that evaluates the cost-effectiveness of drugs, found that covering Wegovy at its current price for just 0.1% of the eligible population would probably force insurers to shift money or increase premiums.

Makers of the GLP-1 drugs have spent considerable resources encouraging doctors to understand obesity as a disease. On Saturday, Carolynn Francavilla, a family physician from Green Mountain Partners for Health in Lakewood, Colo. who has investments in and has given talks sponsored by Lilly, said: We need it all covered so we can provide this care for our patients. We called it a disease more than 10 years ago. Lets treat it.

On Monday, the resolution passed without further discussion.

STATs coverage of chronic health issues is supported by a grant fromBloomberg Philanthropies. Our financial supportersare not involved in any decisions about our journalism.

Excerpt from:
Weight loss drugs should be covered by insurers, AMA says - STAT - STAT

In todays fast-paced world, society is increasingly grappling with issues of weight gain and obesity. This widespread concern affects countless individuals, who often find themselves in a continuous struggle to manage their body weight.

The journey to lose weight is fraught with challenges, many of which stem from trying to find a sustainable and effective method for weight management. Unfortunately, a significant number of people turn to prescription weight loss medications, hoping for quick results. However, these prescription drugs often lead to unsatisfactory outcomes and, more worryingly, can cause a range of side effects.

The quest for losing weight safely and effectively has led many to seek alternatives to prescription weight loss drugs. This shift in approach has seen a growing interest in natural weight loss pills.

These dietary supplements offer a stark contrast to conventional prescription medications. Unlike their pharmaceutical counterparts, these natural solutions boast the advantage of having no severe side effects and aligning better with a healthy diet and lifestyle.

As the weight loss supplements market expands, the number of options available can be overwhelming. How does one discern which fat-burning pills are truly effective? To aid in this endeavor, we have meticulously reviewed and compiled a list of the top fat-burning pills.

These selections represent the best in natural obesity treatment and weight management solutions. So, if youre looking for a safe, natural way to enhance your weight loss efforts, stay tuned as we reveal the best supplements to help you achieve your goals.

Given the vast array of options, ranking the best weight loss pills was challenging.

We meticulously evaluated numerous factors, including effectiveness, ingredient quality, customer reviews, and safety profiles, to ensure our recommendations are reliable and genuinely beneficial for those seeking natural and effective weight management solutions.

Finally, here are our winners:

FitSpresso stands out in weight loss supplements as a powerful, natural option to promote weight loss and support overall health.

This dietary supplement has garnered significant attention for its ability to facilitate healthy weight loss, providing a natural alternative, unlike anti-obesity medications. Each bottle contains 30 vegetable capsules crafted to assist in your fat management journey.

Users can kickstart their weight loss by taking just one capsule of FitSpresso daily with a glass of water. The supplement begins working immediately, boosting energy levels and helping to reshape the body.

Its designed not only to promote weight loss but also to maintain it in the long term. FitSpresso increases metabolism and helps burn fat, thereby reducing body weight effectively.

FitSpressos efficacy lies in its clinically studied ingredients. It includes Lagerstroemia Speciosa, known for its ability to regulate blood glucose; Capsicum annum, which aids in burning body fat; Silybum marianum for liver health; Panax ginseng, which enhances energy; L-carnitine, crucial for fat metabolism; and Chromium picolinate, essential for blood sugar and cholesterol control.

These ingredients work synergistically to reduce body weight, curb unhealthy food cravings, and offer various health benefits.

FitSpresso comes with a generous 180-day money-back guarantee. This policy reflects the companys confidence in its product and ability to assist in fat management journeys.

Choosing FitSpresso means selecting a supplement committed to promoting healthy weight loss. Its natural ingredients are carefully chosen to support blood pressure and blood sugar levels, while its ability to burn fat and reduce body weight is unparalleled.

FitSpresso is the ideal companion for many weight loss journeys, offering a healthier, more natural approach to losing weight and achieving a transformed figure.

LumaLite is a unique supplement that specializes in weight loss. It is the only product that targets and balances IL-6 levels, a protein linked to fat storage.

This supplement, made from 100% natural ingredients and plant extracts, differs from prescription weight loss drugs. Its free from GMOs, preservatives, gluten, and toxins and is produced in an FDA-approved and GMP-certified facility.

LumaLite addresses the IL-6 protein, which, when overproduced, leads to weight gain and fat accumulation in problem areas. By managing this proteins levels, LumaLite helps reduce excess weight and preserve lean muscle mass.

This action not only supports weight loss but also contributes to overall health. The supplement aims to provide significant weight loss without habit-forming side effects common in prescription pills.

The power of LumaLite lies in its blend of 22 super nutrients and natural ingredients, including Ginger, Gum acacia, Brown seaweed extract, Vitamin D3, Green tea extract, Turmeric extract, African mango seed extract, Korean Ginseng, Apple cider vinegar, Fenugreek, Vitamin B12, among others.

These ingredients work synergistically to suppress appetite, support metabolic health, boost energy levels, maintain healthy blood sugar levels, and offer other health benefits.

LumaLite offers a reassuring 60-day money-back guarantee, reflecting its commitment to customer satisfaction and confidence in its products effectiveness.

Choosing LumaLite means opting for a supplement beyond just addressing body mass index. Its a comprehensive solution in an FDA-approved facility, ensuring quality and safety.

By balancing IL-6 protein levels, LumaLite not only aids in fat loss but also helps achieve overall health improvements. Its an innovative solution for those looking to lose weight and maintain a healthy lifestyle.

Puravive emerges as a unique, plant-based weight loss pill, epitomizing the purity and effectiveness of natures offerings. This product stands alone in its category, offering a blend of eight tropical nutrients and compounds, all clinically proven to enhance brown fat levels in the body.

Its 100% natural, non-GMO, and easy to swallow, making it a leader among the best weight loss pills. Made in an FDA-approved and GMP-certified facility, Puravive ensures quality and safety, making it a sought-after solution for chronic weight management.

Puravives mechanism boosts the bodys brown adipose tissue (BAT) levels. According to recent German research, low BAT levels are linked to increased belly fat. This breakthrough understanding positions Puravive as a critical tool in weight reduction.

BAT is known to burn calories 24/7, raising the bodys metabolic rate and thermogenesis. As per Puravives claims, BAT can burn calories 300 times higher than other cells, making this weight loss pill highly effective for those seeking to lose weight without the side effects of prescription medications.

Puravives power lies in its natural ingredients, including Propolis, Holy Basil, Kudzu Root, Luteolin, White Korean Ginseng, Amur Cork Bark, Oleuropein, and Quercetin.

These components synergistically boost BAT levels and improve energy, brain function, cardiovascular health, blood flow, blood sugar levels, healthy cholesterol, and overall well-being.

Puravive comes with an impressive 180-day money-back guarantee, underscoring the companys confidence in its products ability to deliver weight loss and health benefits.

Puravive is an exceptional choice for those seeking results akin to a prescription weight loss drug without the associated side effects. It holistically addresses weight gain and fat management, positively impacting weight-related health conditions.

This effective weight loss pill is ideal for those seeking to manage body weight and improve overall health, backed by a customer-friendly refund policy and affordability.

PhenQ is a unique solution that offers a comprehensive approach to managing weight. Despite being relatively new, it has already aided over 190,000 customers on their weight loss journey.

This natural system targets five areas of metabolic health, making it a unique and practical option for those looking to maintain a healthy body mass index (BMI) while enjoying their favorite treats occasionally.

PhenQs multi-faceted approach is designed to support a fiery metabolism, helping to burn body fat more efficiently. It acts as an appetite suppressant, reducing calorie intake by naturally decreasing cravings. This process not only aids in burning fat but also helps avoid weight regain.

Additionally, PhenQ works to reduce fat accumulation, balance mood, and boost energy levels, providing the drive and motivation necessary for a successful weight loss journey.

The high-quality formula of PhenQ includes a blend of potent ingredients: -Lacys Reset, Capsimax powder, Chromium picolinate, Caffeine (from green coffee bean extract), L-carnitine fumarate, Nopal cactus, Innoslim, and B vitamins.

Unlike other appetite suppressants, these components work together to offer benefits, supporting muscle mass preservation while promoting fat loss.

PhenQ offers a reassuring 60-day money-back guarantee, reflecting its confidence in the products efficacy and its commitment to customer satisfaction.

PhenQ is an ideal choice for those seeking an effective weight management solution. It works like weight loss medication without harsh side effects, providing a natural and balanced approach to managing weight.

Its ability to act as an appetite suppressant, boost metabolism, and support overall health makes it one of the top choices for anyone embarking on a weight loss journey. With its proven results and customer-friendly refund policy, PhenQ is a reliable and effective option for achieving and maintaining weight loss goals.

Alpilean is a unique weight loss supplement that is the only one that leverages an Alpine secret for healthful weight loss. Its a blend of six potent alpine nutrients and plant extracts, each clinically tested and proven to support weight loss and overall health.

This 100% natural, non-GMO formula is distinct from prescription weight loss drugs, offering a non-habit-forming, stimulant-free solution to managing body weight.

The innovative approach of Alpilean lies in targeting low inner body temperature, a newly discovered root cause of slow metabolism and extra belly fat. By optimizing internal body temperature, Alpilean aids in enhancing metabolic rate, helping the body to burn more calories efficiently.

This process supports fat-burning results and helps prevent weight regain problems. Additionally, users report improved mood, better sleep quality, reduced cravings, and increased energy levels, all contributing to successful weight loss.

Alpileans formula includes African Mango Seeds, Golden Algae, Ginger Rhizome, Curcuma Longa, Chromium Picolinate, Drumstick Tree Leaf, and Citrus Bioflavonoids extract.

Each ingredient plays a crucial role in the supplements effectiveness from suppressing appetite and inhibiting the absorption of dietary fats to supporting healthy blood pressure and body fat reduction.

Alpilean comes with a 90-day money-back guarantee, underlining the confidence the makers have in their product and its ability to deliver significant weight loss benefits.

Alpilean is among the best for those seeking alternative weight loss options. Its unique approach to addressing the root cause of weight gain, combined with its all-natural ingredient profile, makes it an ideal choice for sustained weight management.

The supplements ability to support healthy blood pressure and promote overall well-being, along with its affordability and customer-friendly refund policy, makes Alpilean a compelling choice for anyone looking to lose weight and maintain a healthy lifestyle.

Liv Pure is a groundbreaking weight loss supplement that goes beyond traditional methods. It is the only product in the world featuring a proprietary blend designed to optimize liver function.

Liv Pure stands apart from conventional prescription weight loss drugs, focusing on liver purification and fat burning. This unique dual-action formula has already transformed the lives of over 234,000 individuals ranging from 18 to 80 years old.

Liv Pure targets the root cause of low energy, slow metabolism, and unexplained weight gain compromised liver function. Beyond detoxifying, the liver acts as the bodys fat-burning furnace. Liv Pure purifies and optimizes liver function, enhancing the fat-burning process and metabolism.

This approach ensures that food is more likely to be burned as energy rather than stored as body fat, irrespective of its nutritional value. Consequently, it supports weight reduction and helps maintain a healthy body mass index (BMI) while avoiding weight regain. However, users must take it with a balanced diet and workout routine for more intense results.

The formula of Liv Pure is composed of 100% plant-based ingredients such as Sylimarin, Berberine, Betaine, Glutathione, Molybdenum, Chlorogenic Acid, Camellia Sinensis, Resveratrol, and more.

These components are soy-free, dairy-free, vegetarian, and non-GMO and have undergone rigorous third-party inspections for purity. By focusing on liver health, Liv Pure not only aids in weight loss but can also avoid severe liver injury associated with taking prescription weight loss medications.

Liv Pure offers a 60-day money-back guarantee, demonstrating confidence in its products ability to deliver results.

Liv Pure is ideal for anyone looking to lose weight and improve overall health. Unlike traditional weight loss supplements, it addresses liver health as a critical factor in the bodys fat-burning and metabolic processes.

This unique approach helps users lose weight and sustain long-term health advantages, making Liv Pure an innovative and effective solution for weight management and liver health.

Finding the best products requires a meticulous and multi-faceted approach in the crowded, often confusing world of weight loss pills.

Our ranking process for the top weight loss pills was thorough and considered seven critical factors to ensure our recommendations are reliable, effective, and safe for consumers.

The primary consideration in our assessment was the quality and effectiveness of the ingredients in each weight loss pill. We delved into clinical studies and research papers to verify the claimed benefits of each ingredient. Dietary supplements that contain clinically proven, natural ingredients for effective weight management, such as appetite suppressants or fat burners, ranked higher.

Safety should be the primary concern when choosing the most effective weight loss supplements. We thoroughly examined each product for potential side effects. Pills made from natural, non-GMO ingredients with minimal or no reported side effects scored well. We also considered FDA approval and GMP certification indicators of quality manufacturing practices.

Real user experiences offer invaluable insights into a products effectiveness and usability. We scoured through customer reviews to gauge satisfaction levels and the prevalence of any adverse effects. Dietary supplements with overwhelmingly positive feedback ranked higher.

We assessed the cost-effectiveness of each weight loss pill. Best weight loss supplements that offered good value for money without compromising quality were ranked favorably. We also considered if the brands offered discounts, bundle deals, or money-back guarantees.

Trustworthy brands with a precise, transparent approach to their formulations, sourcing, and manufacturing processes were given preference. We also considered the brands market presence and history of customer satisfaction.

The simplicity and convenience of dosage are crucial for adherence to a weight loss supplement regimen. Products with easy-to-follow dosage instructions and a straightforward regimen were rated higher.

Besides weight loss efficacy, we considered the overall benefits of the dietary supplements. Products that supported holistic health improvements, such as enhanced metabolism, better energy levels, and improved mood, were given higher scores.

Its important to note that the FDA does not approve natural weight loss supplements. However, most of these weight loss pills are formulated using 100% natural ingredients which are clinically examined and proven.

Lets take a look at some of the common ingredients in the best weight-loss pills:

Capsicum annum, commonly known as cayenne or red chili pepper, is widely used in weight loss pills. It contains capsaicin, a compound known for its thermogenic properties, meaning it can increase the bodys heat production to burn fat.

This thermogenesis boosts metabolism, leading to more calories burned and weight loss. Capsicum annum also acts as an appetite suppressant, reducing the desire to eat and controlling calorie intake. Additionally, it may improve digestive health and blood circulation.

However, its potency can vary, and high doses might cause discomfort in sensitive individuals. Nonetheless, Capsicum annum remains favored for its natural and influential contribution to weight management.

Green Tea Extract is a prevalent ingredient in weight loss pills, prized for its rich concentration of catechins, particularly epigallocatechin gallate (EGCG). EGCG is known for its powerful antioxidant properties, which can enhance metabolism and aid in fat-burning.

Additionally, Green Tea Extract contains Caffeine, a well-known stimulant that can increase energy expenditure and improve performance during physical activities. Caffeine and catechins synergize to enhance the bodys ability to burn fat, particularly during exercise.

Regular consumption of Green Tea Extract can also have other benefits, including improved heart health and reduced risk of certain types of cancer. However, its essential to consider caffeine sensitivity when using Green Tea Extract supplements.

L-carnitine fumarate is a form of L-carnitine, a naturally occurring amino acid derivative often included in weight loss supplements. Its primary role is facilitating the transport of fatty acids into the mitochondria, the cells powerhouses, where these fats are burned for energy.

This process is crucial for fat metabolism, making L-carnitine fumarate especially beneficial for those seeking to reduce body weight and improve energy levels. Its often touted for supporting enhanced exercise performance and recovery.

L-carnitine fumarate has various benefits, including improved heart health and cognitive function. While generally safe, taking it as directed is essential, as excessive consumption can lead to potential side effects.

Panax Ginseng, also known as Korean Ginseng, is an herb used in traditional medicine and increasingly popular in weight loss pills. Its renowned for boosting energy levels and reducing fatigue, which can be beneficial during weight loss regimes that require high energy for exercise.

Panax Ginseng is also believed to impact insulin sensitivity positively and can help regulate blood glucose levels, a crucial factor in weight management.

Some studies suggest it may mildly affect suppressing appetite and boosting metabolism. Its adaptogenic properties also aid in combating stress, a common factor in weight gain.

African Mango Seeds, derived from the fruit of the Irvingia gabonensis tree, have gained popularity in weight loss supplements due to their potential fat-burning and appetite-suppressing properties. These seeds are fiber-rich, promoting feelings of fullness and reducing overall calorie intake.

This fiber content also helps improve digestive health and regulate sugar levels, crucial in managing cravings and maintaining consistent energy levels. Some studies suggest that African Mango Seeds might positively impact fat metabolism and cholesterol levels, contributing to cardiovascular health.

However, its essential to approach these claims cautiously, as more extensive research is needed to fully understand their effectiveness and safety in long-term use for weight loss.

Though there are many, here are some of the most known prescription weight-loss drugs:

This combination of prescription weight loss medication is primarily used to treat overweight and obesity. Bupropion, initially used to treat depression, combined with naltrexone, which is used to treat alcohol and opioid addiction, works by suppressing appetite and reducing food cravings. However, its not recommended for individuals with high blood pressure or a history of seizures.

A weight loss medication initially developed to treat diabetes, Liraglutide aids in chronic weight management. It regulates appetite and food intake, making it easier to maintain a reduced-calorie diet. This drug may increase the risk of thyroid cancer, so monitoring is essential.

Orlistat is a weight loss drug that reduces the absorption of dietary fats, leading to calorie reduction. It is an effective method for losing weight and is commonly used to treat obesity. Users may experience digestive side effects, and its recommended to follow a low-fat diet to minimize these effects.

A combination drug used for weight loss, Phentermine-topiramate suppresses appetite and increases the feeling of fullness. Phentermine-topiramate is particularly effective for individuals with a high body mass index (BMI) but can cause side effects like dry mouth and constipation.

It is typically prescribed when diet and exercise alone are insufficient for weight loss. Users need to be under medical supervision while taking Phentermine-topiramate due to risks like increased heart rate and potential congenital disabilities.

Semaglutide is among the most potent weight loss medications to treat obesity. It mimics a hormone that targets areas in the brain regulating appetite and food intake, used for treating overweight and obesity. Its also used for type 2 diabetes management and may cause gastrointestinal side effects like nausea and abdominal pain.

This prescription weight loss medication is designed specifically for rare genetic disorders causing obesity. It regulates hunger pathways in the brain, aiding in fat management. It is not recommended for general obesity treatment and may cause side effects like skin darkening and severe liver injury.

While effective in aiding weight reduction, weight loss medications can have various side effects. Commonly observed side effects of weight loss drugs include nausea, constipation, headache, and dizziness.

Some weight loss medications, especially stimulant-type drugs like phentermine-topiramate, can lead to increased heart rate and high blood pressure. Individuals with pre-existing heart conditions need to be cautious when using these medications.

Furthermore, certain weight loss drugs may exacerbate digestive issues. Orlistat, for instance, can cause oily stools and frequent bowel movements. Long-term use of some weight loss medications might also lead to nutrient deficiencies, impacting overall health.

Link:
Review the Top-Rated Weight Loss Pills That Work Best in 2023 - The Daily World

Since doctors have started prescribing medications like Ozempic and Mounjaro for weight loss, demand for the drugs has skyrocketed.

Both drugs were initially developed to treat type 2 diabetes, but have grown in popularity in recent years due to their ability to aid people in losing weight. They are often prescribed off label for weight loss, while their sister drugs Wegovy and the newly approved Zepbound are approved specifically for weight loss.

While each of these drugs are incredibly effective as weight loss tools, they are not easily accessible for everyone due to their high price tag and limited availability. For that reason, its understandable that someone with a prescription might look to make the most of it.

Sue Decotiis, M.D., a Manhattan physician who specializes in weight management, tells The Messenger that there are ways to ensure the drugs reach their full potential.

Hydration is a key element of overall health, but Dr. Decotiis says its especially important for people who are taking medications to aid in weight loss because losing weight can also dehydrate the body.

When you burn fat, youre losing water, Dr. Decotiis says. Not getting enough water will definitely slow down the action of the drug.

She adds that people who are taking these medications will likely be drinking more water anyway because they will feel thirstier, and that often if she has a patient who is still struggling to lose weight on the drug, it is at least partially rooted in not drinking enough water.

The higher the dose someone is taking, the more water they need to drink every day.

Body composition scales go beyond measuring weight, they assess the overall composition of the body, including how much of a persons weight is body fat.

When losing weight, the goal is to lose excess fat, not muscle, so a body composition scale will help to determine whether weight is being lost in an appropriate and healthy manner.

You might lose 20 pounds but if it wasnt fat that you lost then you really arent at your ideal weight, Dr. Decotiis notes.

Body composition scales are not cheap, however, and the price tags for them can climb well into the thousands. In this case, Dr. Decotiis recommends either calling local medi-spas to see if they have one you could use or downloading certain apps that assess body composition.

After getting an initial read from the app, its accuracy could be compared to a body composition scales readings elsewhere. If the readings are similar, then the app could be considered at least somewhat accurate. Both Google Play and Apple have several body composition apps available for free.

All of the above comes with an important caveat: If getting on a scale is in any way triggering, its best to avoid them if possible. While this piece of information can be helpful, its hardly an overall indication of health and you should ignore it if it doesnt serve you.

Dr. Decotiis has her patients try to adhere to some form of intermittent fasting when trying to lose weight. She says that this helps regulate insulin.

If youre eating throughout the day, even if youre snacking on low calorie foods, your insulin still has to rally. And if your insulin is not working that well and it usually isnt if youre overweight that is going to really hamper your ability to turn your metabolism on because your insulin will be constantly working to deal with the blood sugar that youre taking in and its then not able to burn fat.

Intermittent fasting is a nutrition plan that involves eating only during a set amount of time each day often for eight hours and fasting for the rest of the day and night. This meal plan has been shown to provide some health benefits, like weight management and improved blood pressure, and is recommended by many health care providers for certain people.

Dr. Decotiis says that how long and how often a person fasts at a time will vary depending on the individual situation and that anyone looking to start intermittent fasting should consult with a doctor about what works best for them.

Following a nutritious diet should be a staple in anyones life, even if they arent trying to lose weight. However, incorporating protein into your diet is vital for keeping energy levels up while also keeping you feeling fuller for longer when shedding pounds.

How much daily protein a person should consume will depend on their unique situation.

Once an ideal weight has been reached, Dr. Decotiis does not advise immediately discontinuing weight loss medication.

You dont want to go cold turkey, she says. When my patients reach their goal, I start weaning them very gradually.

Although it is not uncommon for people to regain some of the weight they lose while taking these medications and some experts have suggested that people need to continue to take them for the long haul Dr. Decotiis suggests that weight loss can be sustained in most people if they taper off of the medications appropriately while also maintaining the healthy habits they practiced when taking them.

Most people can reset, she says.

The amount of time this will take varies from person to person, but can take a couple of months, she adds, although some people might need more time to taper off the medication.

In many cases, tapering off of drugs correctly and under the guidance of an expert within the realm of weight loss will ensure that someone does not quickly regain all the weight they have lost. However, Dr. Decotiis says that there are still cases when someone might need to stay on the medication long-term.

Ultimately, how well weight loss medications work will vary from person to person and a number of factors will affect the drugs effectiveness. But the steps above, along with a doctors guidance, should help many people reach their goals.

Read more here:
5 Ways to Make the Most of Your Weight Loss Prescription - The Messenger

FDA-approved Zepbound is the brand name for tirzepatide when doctors prescribe the medication for weight loss. Zepbound and other weight loss drugs are extremely expensive, and most insurance companies dont cover them. Experts hope increased competition among drug makers will drive down costs and improve patient access to pricey weight loss medications. Photo: Getty Images

A newly approved weight loss drug called Zepbound may work even better than the popular drug Wegovy while also driving down the cost of multiple weight loss drugs.

The newest crop of weight loss drugs including Zepbound have sticker prices of more than $1,000 per month, and most insurance companies do not cover them. Doctors and patients, alike, are eager see if Zepbound will foster greater competition and price cuts among drug makers, thus improving access to pricey medications.

Medical experts at the U.S. Food and Drug Administration (FDA) gave a much-anticipated green light to Zepbound on Nov. 8.

The FDA previously approved a related drug called Mounjaro, which is made from the same active ingredient in Zepbound: tirzepatide. But Mounjaro was only available to people with Type 2 diabetes.

Approval of Zepbound is highly significant as the new drug and other similar medications change the way both patients and doctors view battles with extra pounds. About 70% of adults in the U.S. have a body mass index or BMI in the overweight or obese range.

This particular medication opens up a new era for obesity medications. It is the first combination peptide to get FDA approval for obesity, saidDr. Cecilia Low Wang, a UCHealth expert on endocrinology, diabetes and metabolism. Im super excited because this drug is so effective in helping people with obesity, which is a challenging medical condition.

While the drugs have produced dramatic results in people who have used them so far, Low Wang underscores the importance of physical activity and healthy eating.

Im glad we now have potent medications for obesity, but these drugs are not a replacement for healthy lifestyle changes. To be healthy, people need to make sure they exercise most days of the week and consistently choose healthy foods, Low Wang said.

So, what is Zepbound? How well does it work? Whats up with the weird name? How is Zepbound related to Mounjaro, Wegovy and Ozempic? How much will Zepbound cost, and will it cause negative side effects like the gastrointestinal problems that Wegovy and Ozempic can cause?

To answer all of your questions about Zepbound, we consulted with Low Wang, who is a professorat theUniversity of Colorado School of Medicineon theAnschutz Medical Campus.

She alsochairs the committeethat advises the FDA about drugs related to endocrinology and metabolism. (Low Wang does not receive funding from the drug companies. And her views do not represent those of the FDA orthe FDA Endocrinologic and Metabolic Drugs Advisory Committee.)

Zepbound is the brand name for the drug tirzepatide when doctors prescribe it for weight loss. Mounjaro is the name of the medication when its used to treat diabetes. (Learn all about Mounjaro.) Both Zepbound and Mounjaro are brand names for the generic drug, tirzepatide.

No. Zepbound is not a pill. Its an injectable medication that patients need to use once a week. It comes in three doses: 5, 10 and 15 milligrams. So far, Zepbound, Mounjaro, Ozempic, and Wegovy are all injections. The drug in Ozempic and Wegovy, semaglutide, is also available in a pill form for Type 2 diabetes called Rybelsus, and doesnt cause as much weight loss.

It suppresses appetite and makes you feel more full. It changes the rate at which your stomach empties, Low Wang said.

During clinical trials, study volunteers who used tirzepatide lost as much as 21% of their body weight.

The average weight loss for study subjects who did not have diabetes and used the largest dose of Zepbound (15 milligrams, once a week) was 18%, according to the FDA.

People who have diabetes tend to lose less weight with these new drugs than those who dont have diabetes. Another study found that people with diabetes who used Zepbound lost an average of 12% of their body weight, FDA officials said.

All of these drugs are part of a new class of weight loss medications that are shaking up treatment of obesity and diabetes. Theyre also sparking drug shortages and economic earthquakes around the world since demand for the drugs is so high. (Read how Wegovy and Ozempic are causing huge economic impacts in Denmark, home of the drugs maker.)

Many people including those who dont have obesity or medical conditions associated with being overweight have been clamoring to get the medications because they are powerful appetite suppressants and work so much better than previous generations of weight loss drugs.

Zepbound and Mounjaro are basically the same drug, but theyre approved for different medical conditions: Zepbound for weight loss and Mounjaro for diabetes.

Similarly, Wegovy and Ozempic are the same drug, but with different names and different doses for different conditions. Wegovy is the name of the drug as its prescribed for weight loss. Ozempic is the name of the drug as its used for diabetes. The generic name for Wegovy and Ozempic is semaglutide.

No. Zepbound and Mounjaro (also known as tirzepatide) work a little differently than Ozempic and Wegovy (also known as semaglutide).

Here are the differences.

First, the drugs are made by different drug companies. Competition between these pharmaceutical companies and others that are working on new weight loss drugs may drive down prices for the expensive medications.

Eli Lilly makes Zepbound and Mounjaro whileNovo Nordisk makes Wegovy and Ozempic.

Eli Lilly is based in the United States while Novo Nordisk is based in Denmark.

Zepbound, Mounjaro, Wegovy and Ozempic work in similar ways to reduce appetite. But Zepbound and Mounjaro are whats called dual-agonist drugs while Wegovy and Ozempic are whats known as single-agonist drugs. These drugs activate important hormone pathways in the body.

Tirzepatide is in a completely new drug class, Low Wang said. Its a combination peptide. This dual agonist approach seems to cause people who use Zepbound or Mounjaro injections to lose even more weight than those who use a medication that only activates one hormone pathway.

These drugs stimulate hormones that help control blood sugar levels and reduce appetite, triggering weight loss.

The hormones are glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP).

Wegovy and Ozempic activate the GLP-1 pathway, while Zepbound and Mounjaro activate two: both GLP-1 and GIP.

Drug makers spend considerable time and money creating brand names for drugs. Presumably, the zep in Zepbound comes from tirzepatide, the generic name for the drug from which Zepbound is made.

Low Wang says that drug makers come up with names that may sound strange to patients because the names need to sound OK in multiple languages, and the drug names cant conflict with or sound too much like existing brand names for pharmaceuticals. Low Wang concedes that the names often sound strange, and Zepbound may be hard for some people to pronounce. But judging by the popularity of the other weight loss drugs, Zepbound may soon become familiar to millions of people around the world.

Yes. Zepbound just like Mounjaro, Wegovy and Ozempic is a prescription medication. If you think you might benefit from using a weight loss drug, schedule an appointment with your doctor.

The FDA approved Zepbound for adults ages 18 and older who are dealing with obesity or are overweight and have additional weight-related health challenges.

Doctors use BMI to classify who is obese or overweight. Low Wang said BMI is far from a perfect measure of a persons health. Some people have a higher BMI and are perfectly healthy. These drugs may not be right for them.

An elevated BMI doesnt tell you everything about a persons health, Low Wang said. A person could be very fit and muscular, and have a higher BMI, but wouldnt need this medication.

Meanwhile, other people who have high BMIs are dealing with serious related health problems like high blood pressure, diabetes, and elevated risk of heart attack, stroke, heart failure or liver disease.

Low Wang encourages people to consult with their doctors.

To qualify for Zepbound, patients need to have a BMI of 30 and higher which means theyre dealing with obesity or a BMI of 27 or greater the marker for being overweight while they are also dealing with at least one other weight-related health condition. These conditions include high blood pressure, high cholesterol or Type 2 diabetes.

The common side effects are very similar to those that patients have experienced with Mounjaro, Wegovy and Ozempic. The most common side effects include nausea, vomiting, diarrhea, decreased appetite, constipation, upper abdominal discomfort and abdominal pain.

In addition, FDA officials have warned that tirzepatide can cause thyroid C-cell tumors in rats. Federal health experts dont know yet whether Zepbound and Mounjaro cause similar tumors including medullary thyroid cancer in humans.

Its not clear whether Zepbound or other weight loss drugs can case depression or suicidal ideation. But Zepbounds drug maker, Eli Lilly, has included a warning with the drug that doctors should monitor their patients for depression or suicidal ideation and should advise patients to immediately stop using Zepbound if they are experiencing any suicidal thoughts.

Weve had this problem with previous weight loss drugs, where they might increase risk of suicide in people with depression, Low Wang said.

Some patients report gastrointestinal problems with these drugs, but many do not have any problems, Low Wang said.

A portion of people who are taking these drugs will have side effects, but a majority tolerate these medications well, Low Wang said.

Her patients have had the best luck when they start with the lowest dose and let their bodies get used to it.

We start patients on a low dose for four weeks, then step up on the dose, Low Wang said.

Low Wang has found that patients do well if they pay close attention to when they start feeling full and stop eating at that point. People will end up dramatically reducing how much they eat. For those who love to eat and cook, taking the drugs can be a challenge.

In addition, foods that are rich in fat tend to increase negative gastrointestinal side effects.

The list price of Zepbound is more than $1,000 per month. And most health insurance companies are not yet covering these new weight loss medications. All of them are very expensive now. But Low Wang and other experts are hoping that increased competition among drug makers will drive down the costs of the medications.

In addition, recent studies of people using semaglutide, the active ingredient in Ozempic and Wegovy, suffered dramatically fewer adverse cardiovascular events like heart attacks and strokes. The studies have found benefits in both people with diabetes and those who were obese but did not have diabetes.

It will take time before researchers complete studies to determine if Zepbound produces similarly positive cardiovascular benefits.

If the drugs help people lose weight while also preventing heart attacks, strokes and other cardiovascular health problems, Low Wang expects more insurance companies to cover the drugs. Pressure also could increase for the federal government to cover the drugs through Medicare and Medicaid.

The pros are that Zepbound helps many people lose a dramatic amount of weight. It may also help reduce other health problems associated with excess weight.

There are multiple potential downsides to using Zepbound, Mounjaro, Ozempic and Wegovy. (Read more about eight reasons to be cautious about Ozempic and Wegovy.)

Low Wang emphasizes that its vital for individuals to speak with their doctors.

Patients have to use reliable sources for their medical information, and doctors need to think about an individuals risk-benefit balance. For each person, its going to be different, she said.

Low Wang encourages patients to review information from reliable experts including the Endocrine Society and the American Association of Clinical Endocrinology or AACE.

Yes. People who are pregnant should never take these medications. They need to be eating well and gaining weight to support their pregnancies.

FDA officials say people who have a personal or family history of medullary thyroid cancer should not use Zepbound along with patients with Multiple Endocrine Neoplasia syndrome type 2.

In addition, Zepbound has not been studied in patients with a history of pancreas inflammation (pancreatitis) or severe gastrointestinal disease (including severe gastroparesis, a condition that affects normal movement of the muscles in the stomach), according to the FDA.

Low Wang said many new drugs are being developed now.

There are going to be many more combination peptides dual agonists and triple agonists, she predicted.

In addition to double peptide medications, like Zepbound, there will also be triple peptide drugs.

We have to be aware of all of the side effects, and people should talk to their doctors. But the future for obesity treatment is really exciting.

Link:
How does the weight loss drug Zepbound compare to Mounjaro ... - UCHealth Today

There are several options when it comes to maintaining your weight. Dr. Ivanesa Pardo, a board-certified general and bariatric surgeon at MedStar Washington Hospital Center discusses which ones may be right for you.

This content is sponsored by MedStar Washington Hospital Center.

The U.S. obesity prevalence was about 42% in 2020, according to the Centers for Disease Control and Prevention (CDC). Conditions related to obesity include diabetes, heart disease, stroke and some cancers. The CDC also said these diseases are among the leading causes of preventable, premature death.

Fortunately, there are several options when it comes to maintaining your weight.

Dr. Ivanesa Pardo, a board-certified general and bariatric surgeon at MedStar Washington Hospital Center, said she encourages patients to use traditional methods like diet and exercise.

She recommends 60 minutes of exercise three times a week, avoiding trans fat, and moderating your intake of sugar and liquid calories. Dr. Pardo also stressed the importance of avoiding restrictive diets.

If youre starving yourself, when you finally start eating, your body starts accumulating all the calories, because it thinks when am I going to starve again. So you start taking extra into your reserve, Dr. Pardo explained.

Although diet and exercise can be effective, Dr. Pardo said results could be hard to maintain when only using the two methods alone.

We know that diet and exercise alone even though they could be successful in helping weight loss they fail in maintenance, she said.

Your lifestyle can also make it more challenging to incorporate diet and exercise into your daily routine.

And then you have people that have obesity they have limitations in their activity, Dr. Pardo said. They have arthritis or respiratory problems because theyre carrying that extra weight. That makes it much harder to be more active.

Other options include weight loss medication, but Dr. Pardo warns patients to be weary of gimmicks.

Obesity is not a one single-cause problem, and not one thing caused the obesity, so we cant expect that one ingredient is going to then make you lose all the weight, she said.

Prescription medications for weight loss have evolved over the years, and Dr. Pardo said weight loss clinics have produced some degree of success with medications like phentermine, and B-12 injections. However, she said newer medication GLP-1 agonists such as ozempic, Wegovy, and Mounjaro have been proven to be very effective.

These are now injectables instead of pills, and so far, the results are very promising. The problem is, of course, we dont have long term data, she said.

Some people cant tolerate them due to the side effects, which include gastrointestinal issues. Some may not experience any weight loss.

So its like any tool. It may or may not work. But as of now, these are the medications that have proven to be the most efficacious, she said. They can cause somewhere between five and 10% weight loss within several months.

Dr. Pardo also said GLP-1 agonists are a good alternative to bariatric surgery, another effective weight loss option.

The American Society for Metabolic and Bariatric Surgery recently dropped the body mass index requirement from 40 to 35 without comorbidities and from 35 to 30 for people with comorbidities. Dr. Pardo praised the changes, saying surgery can reverse diabetes fully, so why wait?

Cost can be a deterring factor in receiving bariatric surgery, but Dr. Pardo said insurances are now covering the procedure more freely. She added that the data showed that it was more affordable to pay for surgery versus the prolonged, ongoing treatment of not only obesity or medications, but diabetes.

Only about one percent of people that qualify for surgery receive it. According to Dr. Pardo, this is because of the stigma associated with the procedure.

And the reality is that death from the surgery is less than half a percent. Bariatric surgery now is safer than a hip replacement, its safer than even taking your gallbladder out, she said.

Dr. Pardo also highlighted that bariatric surgery is not the end of a patients weight loss journey. Someone who just underwent the procedure must focus on nutrition and portion control since the stomach will be smaller. This includes learning to read labels, and consuming high protein and healthy fats.

Obesity is a chronic disease most people will fight their entire lives, and Dr. Pardo says the goal is to help people live healthier, longer lives.

Even if youre successful in weight loss, it doesnt mean that youre done, you still have to prevent weight regain.

Read more about weight management options on the MedStar Washington Hospital Center website.

See the rest here:
Weighing your weight loss options: Which is right for you - WTOP

Rapando C, Nyagero J, Wakhu F, editors. Feeding Habits associated with overweight and obesity amongst secondary School students in Private and Public schools in Langata Nairobi Kenya2017.

Norris T, Cole TJ, Bann D, Hamer M, Hardy R, Li L, et al. Duration of obesity exposure between ages 10 and 40 years and its relationship with cardiometabolic disease risk factors: A cohort study. PLoS Med. 2020;17:e1003387.

Article PubMed PubMed Central Google Scholar

Roth GA, Mensah GA, Johnson CO, Addolorato G, Ammirati E, Baddour LM, et al. Global Burden of Cardiovascular Diseases and Risk Factors, 1990-2019: Update From the GBD 2019 Study. J Am Coll Cardiol. 2020;76:29823021.

Article PubMed PubMed Central Google Scholar

Hajek A, Brettschneider C, van der Leeden C, Lhmann D, Oey A, Wiese B, et al. Prevalence and factors associated with obesity among the oldest old. Arch Gerontol Geriatr. 2020;89:104069.

Article PubMed Google Scholar

Luhar S, Timus IM, Jones R, Cunningham S, Patel SA, Kinra S, et al. Forecasting the prevalence of overweight and obesity in India to 2040. PLoS One. 2020;15:e0229438.

Article CAS PubMed PubMed Central Google Scholar

Ward ZJ, Bleich SN, Cradock AL, Barrett JL, Giles CM, Flax C, et al. Projected U.S. State-Level Prevalence of Adult Obesity and Severe Obesity. N Engl J Med. 2019;381:244050.

Article PubMed Google Scholar

Wang J, Wang F, Chen H, Liu L, Zhang S, Luo W, et al. Comparison of the Effects of Intermittent Energy Restriction and Continuous Energy Restriction among Adults with Overweight or Obesity: An Overview of Systematic Reviews and Meta-Analyses. Nutrients. 2022;14:2315.

Article CAS PubMed PubMed Central Google Scholar

Halpern B, Mendes TB. Intermittent fasting for obesity and related disorders: unveiling myths, facts, and presumptions. Arch Endocrinol Metab. 2021;65:1423.

PubMed PubMed Central Google Scholar

Pannen ST, Maldonado SG, Nonnenmacher T, Sowah SA, Gruner LF, Watzinger C, et al. Adherence and Dietary Composition during Intermittent vs. Continuous Calorie Restriction: Follow-Up Data from a Randomized Controlled Trial in Adults with Overweight or Obesity. Nutrients. 2021;13:1195.

Article CAS PubMed PubMed Central Google Scholar

Maroofi M, Nasrollahzadeh J. Effect of intermittent versus continuous calorie restriction on body weight and cardiometabolic risk markers in subjects with overweight or obesity and mild-to-moderate hypertriglyceridemia: a randomized trial. Lipids Health Dis. 2020;19:216.

Article CAS PubMed PubMed Central Google Scholar

Varady KA. Intermittent versus daily calorie restriction: which diet regimen is more effective for weight loss? Obes Rev. 2011;12:e593601.

Article CAS PubMed Google Scholar

Varady KA, Cienfuegos S, Ezpeleta M, Gabel K. Cardiometabolic Benefits of Intermittent Fasting. Annu Rev Nutr. 2021;41:33361.

Article CAS PubMed Google Scholar

Saad R. Effects of Intermittent Fasting on Health, Aging, and Disease. N Engl J Med. 2020;382:1773.

PubMed Google Scholar

Brandhorst S, Longo VD. Dietary Restrictions and Nutrition in the Prevention and Treatment of Cardiovascular Disease. Circ Res. 2019;124:95265.

Article CAS PubMed Google Scholar

St-Onge MP, Ard J, Baskin ML, Chiuve SE, Johnson HM, Kris-Etherton P, et al. Meal Timing and Frequency: Implications for Cardiovascular Disease Prevention: A Scientific Statement From the American Heart Association. Circulation. 2017;135:e96e121.

Article PubMed PubMed Central Google Scholar

Moon S, Kang J, Kim SH, Chung HS, Kim YJ, Yu JM, et al. Beneficial Effects of Time-Restricted Eating on Metabolic Diseases: A Systemic Review and Meta-Analysis. Nutrients. 2020;12:1267.

Article CAS PubMed PubMed Central Google Scholar

Cho Y, Hong N, Kim KW, Cho SJ, Lee M, Lee YH, et al. The Effectiveness of Intermittent Fasting to Reduce Body Mass Index and Glucose Metabolism: A Systematic Review and Meta-Analysis. J Clin Med. 2019;8:1645.

Article CAS PubMed PubMed Central Google Scholar

Meng H, Zhu L, Kord-Varkaneh H, Santos HO, Tinsley GM, Fu P. Effects of intermittent fasting and energy-restricted diets on lipid profile: A systematic review and meta-analysis. Nutrition. 2020;77:110801.

Article CAS PubMed Google Scholar

Pureza I, Macena ML, da Silva Junior AE, Praxedes DRS, Vasconcelos LGL, Bueno NB. Effect of early time-restricted feeding on the metabolic profile of adults with excess weight: A systematic review with meta-analysis. Clin Nutr. 2021;40:178899.

Article CAS PubMed Google Scholar

Stekovic S, Hofer SJ, Tripolt N, Aon MA, Royer P, Pein L, et al. Alternate Day Fasting Improves Physiological and Molecular Markers of Aging in Healthy, Non-obese Humans. Cell Metab. 2020;31:87881.

Article CAS PubMed Google Scholar

Schbel R, Nattenmller J, Sookthai D, Nonnenmacher T, Graf ME, Riedl L, et al. Effects of intermittent and continuous calorie restriction on body weight and metabolism over 50 wk: a randomized controlled trial. Am J Clin Nutr. 2018;108:93345.

Article PubMed PubMed Central Google Scholar

Tinsley GM, Moore ML, Graybeal AJ, Paoli A, Kim Y, Gonzales JU, et al. Time-restricted feeding plus resistance training in active females: a randomized trial. Am J Clin Nutr. 2019;110:62840.

Article PubMed PubMed Central Google Scholar

Patterson RE, Sears DD. Metabolic Effects of Intermittent Fasting. Annu Rev Nutr. 2017;37:37193.

Article CAS PubMed Google Scholar

He S, Wang J, Zhang J, Xu J. Intermittent Versus Continuous Energy Restriction for Weight Loss and Metabolic Improvement: A Meta-Analysis and Systematic Review. Obesity (Silver Spring). 2021;29:10815.

Article PubMed Google Scholar

Rynders CA, Thomas EA, Zaman A, Pan Z, Catenacci VA, Melanson EL. Effectiveness of Intermittent Fasting and Time-Restricted Feeding Compared to Continuous Energy Restriction for Weight Loss. Nutrients. 2019;11:2442.

Article CAS PubMed PubMed Central Google Scholar

Adafer R, Messaadi W, Meddahi M, Patey A, Haderbache A, Bayen S, et al. Food Timing, Circadian Rhythm and Chrononutrition: A Systematic Review of Time-Restricted Eatings Effects on Human Health. Nutrients. 2020;12:3770.

Article PubMed PubMed Central Google Scholar

Patikorn C, Roubal K, Veettil SK, Chandran V, Pham T, Lee YY, et al. Intermittent Fasting and Obesity-Related Health Outcomes: An Umbrella Review of Meta-analyses of Randomized Clinical Trials. JAMA Netw Open. 2021;4:e2139558.

Article PubMed PubMed Central Google Scholar

Varady KA, Cienfuegos S, Ezpeleta M, Gabel K. Clinical application of intermittent fasting for weight loss: progress and future directions. Nat Rev Endocrinol. 2022;18:30921.

Article PubMed Google Scholar

Elortegui Pascual P, Rolands MR, Eldridge AL, Kassis A, Mainardi F, L K-A, et al. A meta-analysis comparing the effectiveness of alternate day fasting, the 5:2 diet, and time-restricted eating for weight loss. Obesity. 2023;31:921.

Article PubMed Google Scholar

Silverii GA, Cresci B, Benvenuti F, Santagiuliana F, Rotella F, Mannucci E. Effectiveness of intermittent fasting for weight loss in individuals with obesity: A meta-analysis of randomized controlled trials. Nutr Metab Cardiovasc Dis. 2023;33:14819.

Article PubMed Google Scholar

Hutton B, Salanti G, Caldwell DM, Chaimani A, Schmid CH, Cameron C, et al. The PRISMA extension statement for reporting of systematic reviews incorporating network meta-analyses of health care interventions: checklist and explanations. Ann Intern Med. 2015;162:77784.

Article PubMed Google Scholar

Higgins JPT, Thomas J, Chandler J, Cumpston M, Li T, Page MJ, et al. Cochrane Handbook for Systematic Reviews of Interventions version 6.2 (updated February 2021). Cochrane, 2021. Available from http://www.training.cochrane.org/handbook.

Salanti G, Ades AE, Ioannidis JP. Graphical methods and numerical summaries for presenting results from multiple-treatment meta-analysis: an overview and tutorial. J Clin Epidemiol. 2011;64:16371.

Article PubMed Google Scholar

Sterne JAC, Savovi J, Page MJ, Elbers RG, Blencowe NS, Boutron I, et al. RoB 2: a revised tool for assessing risk of bias in randomised trials. Bmj. 2019;366:l4898.

Article PubMed Google Scholar

McGuinness LA, Higgins JPT Risk-of-bias VISualization (robvis): An R package and Shiny web app for visualizing risk-of-bias assessments. Research Synthesis Methods. 2020;n/a(n/a).

Tu YK. Using Generalized Linear Mixed Models to Evaluate Inconsistency within a Network Meta-Analysis. Value Health. 2015;18:11205.

Article PubMed Google Scholar

Yu-Kang T. Node-Splitting Generalized Linear Mixed Models for Evaluation of Inconsistency in Network Meta-Analysis. Value Health. 2016;19:95763.

Article PubMed Google Scholar

Lu G, Ades AE. Assessing Evidence Inconsistency in Mixed Treatment Comparisons. J Am Stat Assoc. 2006;101:44759.

Article CAS Google Scholar

Lu G, Ades AE. Combination of direct and indirect evidence in mixed treatment comparisons. Stat Med. 2004;23:310524.

Article CAS PubMed Google Scholar

Mbuagbaw L, Rochwerg B, Jaeschke R, Heels-Andsell D, Alhazzani W, Thabane L, et al. Approaches to interpreting and choosing the best treatments in network meta-analyses. Syst Rev. 2017;6:79.

Article CAS PubMed PubMed Central Google Scholar

Sterne JA, Egger M, Smith GD. Systematic reviews in health care: Investigating and dealing with publication and other biases in meta-analysis. Bmj. 2001;323:1015.

Article CAS PubMed PubMed Central Google Scholar

White I Network: Stata module to perform network meta-analysis. Statistical software components 2017.

Chaimani A, Higgins JP, Mavridis D, Spyridonos P, Salanti G. Graphical tools for network meta-analysis in STATA. PLoS One. 2013;8:e76654.

Article CAS PubMed PubMed Central Google Scholar

Carter S, Clifton PM, Keogh JB. The effects of intermittent compared to continuous energy restriction on glycaemic control in type 2 diabetes; a pragmatic pilot trial. Diabetes Res Clin Pract. 2016;122:10612.

Article CAS PubMed Google Scholar

Carter S, Clifton PM, Keogh JB. The effect of intermittent compared with continuous energy restriction on glycaemic control in patients with type 2 diabetes: 24-month follow-up of a randomised noninferiority trial. Diabetes Res Clin Pract. 2019;151:119.

Article CAS PubMed Google Scholar

Catenacci VA, Pan Z, Ostendorf D, Brannon S, Gozansky WS, Mattson MP, et al. A randomized pilot study comparing zero-calorie alternate-day fasting to daily caloric restriction in adults with obesity. Obesity (Silver Spring). 2016;24:187483.

Article CAS PubMed Google Scholar

Conley M, Le Fevre L, Haywood C, Proietto J. Is two days of intermittent energy restriction per week a feasible weight loss approach in obese males? A randomised pilot study. Nutr Diet. 2018;75:6572.

Article PubMed Google Scholar

Gabel K, Kroeger CM, Trepanowski JF, Hoddy KK, Cienfuegos S, Kalam F, et al. Differential effects of alternate-day fasting versus daily calorie restriction on insulin resistance. Obesity (Silver Spring). 2019;27:144350.

Article CAS PubMed Google Scholar

Harvie M, Wright C, Pegington M, McMullan D, Mitchell E, Martin B, et al. The effect of intermittent energy and carbohydrate restriction v. daily energy restriction on weight loss and metabolic disease risk markers in overweight women. Br J Nutr. 2013;110:153447.

Article CAS PubMed PubMed Central Google Scholar

Harvie MN, Pegington M, Mattson MP, Frystyk J, Dillon B, Evans G, et al. The effects of intermittent or continuous energy restriction on weight loss and metabolic disease risk markers: a randomized trial in young overweight women. Int J Obes (Lond). 2011;35:71427.

Article CAS PubMed Google Scholar

He CJ, Fei YP, Zhu CY, Yao M, Qian G, Hu HL, et al. Effects of intermittent compared with continuous energy restriction on blood pressure control in overweight and obese patients with hypertension. Front Cardiovasc Med. 2021;8:750714.

Article PubMed PubMed Central Google Scholar

Headland ML, Clifton PM, Keogh JB. Effect of intermittent compared to continuous energy restriction on weight loss and weight maintenance after 12 months in healthy overweight or obese adults. Int J Obes (Lond). 2019;43:202836.

Article CAS PubMed Google Scholar

Here is the original post:
Network meta-analysis of three different forms of intermittent energy ... - Nature.com

Page 12«..11121314..2030..»

Home » Long Term Weight Loss » Page 12