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Feb 21

Nissan selects Houston to debut its on-demand subscription service – InnovationMap

Sticking to a fitness routine can be challenging what with the myriad exercises, personal trainers, gyms, and apps. Creating a personalized program to fit specific goals, gain confidence, and take control of health concerns is what drove Houstonian Lindsay Huelse to launch a wildly popular female wellness app.

The FITT Cycle (which stands for Fasting, Intervals, and Target Training) app incorporates fitness routines, nutrition plans, accountability, community, and entrepreneurship.

"Historically, fitness apps are great for memberships," Huelse tells CultureMap. "I wanted to create a platform for returning clients where they could have stability and ditch the diets."

Since its launch in December 2019, Huelse says she has seen a membership growth of almost 2,000 percent, noting that there is no other app with The FITT Cycle's features. She calls it a hybrid of My Fitness Pal, the Peloton App, Facebook communities, and more.

"Everything is in one place," she adds.

The app combines exercise and diet to make for a more complete health tracking app than existing technology. Photo courtesy of The FITT Cycle

A retired nurse, Huelse is now a certified nutrition coach and self-proclaimed "queen of carb cycling," a regimen that focuses on alternating daily carbohydrate intake to promote weight loss and overcome weight loss plateaus.

Fitness has always played a role in Huelse's life, both on and off the field. She played soccer competitively throughout high school and college but it wasn't until her pre-nursing track where she became intrigued by nutrition.

"It was something I didn't learn growing up," Huelse adds. "I was fascinated with fueling my body to help it function properly."

Upon graduation, she worked in the intensive care unit before retiring in 2018 from the corporate world of home health and hospice. As a geriatric nurse, she says she enjoyed educating the elderly on manageable ways to change their diet and reduce inflammation, something they're not always willing to do.

"This led me to be passionate about helping women with preventative measures to decrease inflammation and create food freedom," she says.

With multiple features, including carb cycling macros and an in-app nutrition tracker for weight loss success; daily workouts and targeted training for the home or gym; an in-app guide to intermittent fasting with a timer to indicate when the fasting window is complete; a community to keep members accountable; and a library of more than 250 recipes, The FITT Cycle app is truly customizable for your health, wellness, and fitness goals.

"As a woman who used to work out for hours at a time and follow a clean nutrition plan, I was gaining weight but couldn't understand why," she says. "There's a science to reaching your fitness goals and through learning about my clients who have children, are older, or are postmenopausal helped me design the app to show them you don't have to feel fatigued or struggle with losing weight."

Huelse adds that the last diet her clients followed will be the last diet they ever chase.

Every one of Huelse's clients who join The FITT Cycle app has the opportunity to earn a 50 percent commission for anyone they enroll in the app. Huelse says her vision for creating a cycle of entrepreneurship is to give back to her community and to those who helped her on her path to entrepreneurship.

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This article originally ran on CultureMap.

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Nissan selects Houston to debut its on-demand subscription service - InnovationMap


Feb 21

Why Tivity Health Stock Tumbled Today – Nasdaq

What happened

Shares of Tivity Health(NASDAQ: TVTY) were plunging after the Nutrisystem parent announced disappointing fourth-quarter earnings and said that its CEO would be stepping down.

As a result, the stock finished down 45.5% on Thursday.

Image source: Getty Images.

Tivity said revenue jumped 78% to $272.8 million, which missed estimates at $275.2 million. The jump in sales was due to its acquisition of Nutrisystem, which closed in March 2019, so the fourth quarter will be the last to benefit from lapping a full quarter without Nutrisystem.

The big issue in the quarter was a $377.1 million asset impairment charge relating to goodwill from the Nutrisystem acquisition and its brand name. Tivity had paid $1.3 billion for the weight-loss company. Due to challenges with Nutrisystem, adjusted earnings per share fell from $0.73 to $0.40, which was below the analyst consensus at $0.55.

The company also said that CEO Donato Tramuto was leaving, effective immediately, and would be replaced by interim CEO Robert Greczyn Jr., one of the company's directors, while the company conducts a search for a permanent CEO. Tramuto's ouster also appears to be a result of the struggles with the Nutrisystem acquisition.

Greczyn acknowledged the challenges with Nutrisystem: "While the nutrition segment had a disappointing end to 2019, it remains profitable, and we believe it will continue to generate significant cash flow. Management and our Board of Directors are committed to making the right investments for this business with a focus on innovation, execution, and new advertising strategies to return the business to growth."

For the year ahead, management expects revenue of $1.243 billion to $1.285 billion, up 10% to 14% from 2019, which is worse than expectations at $1.34 billion. On the bottom line, the company continues to anticipate headwinds from Nutrisystem, since it forecast adjusted EBITDA of $190 million to $205 million for the year, down from $222 million in 2019. Given that guidance, as well as the asset impairment and the CEO firing, it's not surprising to see the weight-loss stock nearly slashed in half, since it will take some work to get Tivity back on the right track.

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Why Tivity Health Stock Tumbled Today - Nasdaq


Feb 19

What Is Speed Keto And Can It Help Me Lose Weight Sustainably? – Women’s Health

If you know anything about the keto diet, you understand that the eating style is preeettyyy restrictive, and not the easiest to stick with long-term. Still, fans of the high-fat, low-carb diet tout benefits like weight loss breakthroughs, more energy, clearer skin, and less cravings for sugar.

Sounds wonderful, right? Well, a new version of keto aimed at upping all of these perks has keto fanatics buzzing, but some health and nutrition pros say it may be even more unsustainable than the keto diet you already know. The new version is called Speed Keto, and dietitians aren't exactly recommending it if you're looking to lose weight or start eating healthier.

Still, if you're curious about the eating plan and its origin, here's what you need to know.

Basically, Speed Keto is a combination of the traditional keto diet (made up of 60 to 70 percent fat, 15 to 30 percent protein, and 5 to 10 percent carbs) and intermittent fasting (IF), which involves alternating between various periods of fasting and eating. One of the most common styles of IF is the 16:8 method, in which you fast for 16 hours and can eat during the 8-hour period that follows.

When it comes to Speed Keto, the goal is to get the dieter down to one meal per day, which also has to fit into the keto guidelines of being high-fat and low-carb. The goal of eating less carbs is to get the body into a state of ketosis, which is when your body burns fat, instead of carbohydrate stores, for fuel, which can lead to weight loss.

Speed Keto, which you can buy as a digital program, was created by Harlan Kilstein, an expert coach and motivator with a doctor of education degree, according to his website. Per the site, Speed Keto is meant to simplify the dieting process and help people get past weight-loss plateaus that might occur after eating a traditional keto diet for a few weeks.

"I think keto and 'Speed Keto' diets will result in weight loss," says Hillary Cecere, registered dietitian at Eat Clean Bro. "Any time food is restricted and a calorie deficit occurs, so will weight loss, and when your eating window is smaller, you are more likely to consume less calories."

That being said, Cecere doesn't support the diet as a healthy way of eating. "This diet is unsustainable. Once it's no longer being utilized, weight gain will happen," Cecere says. "I also think it eliminates a lot of nutrient-dense foods. This diet is not for health or longevityit's only for quick weight loss."

In order to maintain weight loss, it's crucial that the diet you follow is something you can sustain long-term, notes Cecere. And if eating keto in general isn't your cup of tea, that's totally fine, too. "You don't need to be in ketosis to lose weight," she says. "Weight loss is determined by calorie deficitthere are plenty of other healthy, sustainable ways to lose weight if that's something you're interested in."

It's also worth noting that combining keto and intermittent fasting isn't exactly new. Many people have been following a diet that combines the two because eating mostly fats and proteins does fill you up and make it easier to fast between meals. The difference here is that Speed Keto recommends a specific IF schedule and one meal a day.

"Combining a super restrictive diet with long periods of non-eating is not good," Scott Keatley, RD, of Keatley Medical Nutrition Therapy, previously told WH. The body will cannibalize its own muscle for energy if intake from food is too low but the body does not differentiate between something like a calf muscle or a heart muscle. Keatley added that all your important organs are made of smooth muscle, "and going on a diet like this may harm something like your bladder or lungs just as much as provide fat loss."

It's also worth noting that following a regular keto diet can already have some not-so-pleasant side effects. At the end of the day, whether you want to follow a keto eating plan is up to you, but experts generally warn against pairing keto with an extreme intermittent fasting schedule in the way that the Speed Keto diet does, experts caution. Whatever you choose diet-wise, it's always wise to talk to a dietitian or trusted MD before you drastically overhaul your eating plan.

The bottom line: Speed Keto may not be a sustainable option when it comes to weight loss.

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What Is Speed Keto And Can It Help Me Lose Weight Sustainably? - Women's Health


Feb 19

The Benefits of Intermittent Fasting – The New York Times

Although there have been a number of recent studies assessing the effects of intermittent fasting on people, none are long term, and the vast majority of disease-related findings stem from research on laboratory animals. For example, in an animal model of stroke, those fed only intermittently suffered less brain damage because they were better able to resist the stress of oxygen and energy deprivation.

Other animal studies have shown a robust disease-modifying benefit of intermittent fasting on a wide range of chronic disorders, including obesity, diabetes, cardiovascular disease, cancers and neurodegenerative brain diseases, the researchers reported. Their review of both animal and human studies found improvements in a variety of health indicators and a slowing or reversing of aging and disease processes.

For example, human studies of intermittent fasting found that it improved such disease indicators as insulin resistance, blood fat abnormalities, high blood pressure and inflammation, even independently of weight loss. In patients with multiple sclerosis, intermittent fasting reduced symptoms in just two months, a research team in Baltimore reported in 2018.

If you think evolutionarily, Dr. Mattson said, predators in the wild fight for prey in the fasting state and are better at recovering from inevitable injuries. The human counterpart people who evolved in feast-or-famine environments would not have survived unless somehow protected by fasting.

Our human ancestors did not consume three regularly spaced large meals, plus snacks, every day, nor did they live a sedentary life, the researchers wrote. The studies they analyzed showed that most if not all organ systems respond to intermittent fasting in ways that enable the organism to tolerate or overcome the challenge and then return to normal.

Dr. Mattson explained that during a fast, the body produces few new proteins, prompting cells to take protein from nonessential sources, break them down and use the amino acids to make new proteins that are essential for survival. Then, after eating, a lot of new proteins are produced in the brain and elsewhere.

A reasonable question might be How safe is intermittent fasting? When fats are used for energy, they produce substances called ketone bodies that regulate the expression and activity of many proteins and molecules that are known to influence health and aging, the researchers reported. Ketosis, a build-up of acidic ketones in the blood, is a state that the Atkins diet, the ketogenic diet and other carbohydrate-restricted diets aim to achieve. Taken to extremes, however, ketosis can damage the liver, kidneys and brain and is especially dangerous to people with various chronic disorders like diabetes and heart disease.

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The Benefits of Intermittent Fasting - The New York Times


Feb 19

David Reagan, a Personal Trainer from Atlanta, Shares Five Ways to Stay Motivated on Your Weight Loss Journey – Thrive Global

Weight loss can be one of the most rewarding or frustrating journeys for an individual. Many people struggle with its process, hence why there is a market surrounding how to accomplish weight loss. For many, losing weight can feel like a never-ending start line with no finish in sight.

The good news is David Reagan, Atlanta native and a NASM certified personal trainer who specializes in weight loss, knows what reaching your weight loss goals boils down too: motivation. Below, Reagan shares five ways to gain motivation and keep it during this crucial health trek.

1. Have realistic expectations that fit your lifestyle

The easiest way to lose motivation when starting your weight loss journey is to set unrealistic goals that do not fit in with your lifestyle. If you have a hectic schedule and travel regularly, you might not set yourself up for success by purchasing a local gym membership and planning to spend an hour at the gym Monday through Friday. Research and explore multiple fitness options and set maintainable goals that you know you can keep up with along with your life plan.

2. Determine your why

Why do you want to lose weight? Is it to gain self-confidence? Improve your heart health for your daughters wedding? Whatever your logical decision as to why you want to lose weight, its essential that you identify it and write it on paper. Writing down your reasons why will aid in maintaining determination and staying committed. It helps to read your whys daily and before your work out for long-term achievement.

3. Clean out your closet and focus on a feeling

Do you fluctuate between sizes when the motivation for weight loss comes and goes? Stay motivated to be the size that makes you feel your best by cleaning out your closet and keeping only the clothes that you feel most confident when wearing. Rather than focusing on the number on the scale, hone in on your self-assurance and courage when you are feeling and looking your best and how it positively affects other areas in your life.

4. Treat yourself

When fatigue hits hard mid-week and going to the gym is the last thing you want to do, think about the things you would love to do instead. Allow yourself to set goals in the gym that result in acting on the things that give you your Zen. Tell yourself if you stick to your fitness goals until the weekend, you will treat yourself to your favorite massage or buy the book youve been holding in your Amazon cart. However, try to reward yourself without food.

5. Seek competitions

A great way to stay motivated is to focus on competitive goals to work towards accomplishing. Maybe you just started running, and want to stay excited about it. Try signing up for a 5k to work towards, then a 10k, and continue to escalate your goals forward. Compete against yourself, others, or even join a team to work together in competition. Weight loss competitions that are team-based and overall social influence help you lose 20 percent more weight than on your own.

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David Reagan, a Personal Trainer from Atlanta, Shares Five Ways to Stay Motivated on Your Weight Loss Journey - Thrive Global


Feb 19

Macro Diet vs. Macrobiotic Diet: What’s the Difference? – msnNOW

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If you Google nutrition or weight loss, you'll most likely come across macros or the macrobiotic dietor bothin your search results. "Both the macro and macrobiotic diets have been around for a very long time," says Lauren Harris-Pincus, MS, RDN, a New York City-based registered dietitian author of The Protein-Packed Breakfast Club. "Although they sound similar, they are totally unrelated." But what exactly are these diets? How do you follow them? And most importantly: Are they effective?

The macro diet is directly related to the basics of nutritional science. "A macro diet refers to counting macronutrients," says Harris-Pincus. "These include protein, carbohydrates, and fat." Examples of lean proteins include tofu, salmon, and chicken breast. Carbohydrates are found in whole grains such as oats and whole-grain bread, vegetables, fruits, and more. Healthy fats include avocado, olive oil, nuts, and seeds.

In a nutshell, you track your macros by tracking the calories you get from each macronutrient. Protein and carbs each contain four calories per gram, and fat contains nine calories per gram. To follow the diet, you'll want to establish how many of each macro you want to consume in a day based on your daily calorie intake goal.

"You are looking to achieve a certain calorie level with a calculated breakdown of these macros," says Harris-Pincus, and the goals will vary depending on what you're trying to do with your diet. For example, "Some people may want a higher protein intake, and some may want higher fat or lower carbs. It's a way of flexible dieting that does not strongly consider the source of the food, just its macro distribution. So if you want a doughnut, as long as you fit it into your daily macros, that's no problem."

Indeed, you can eat anything on the macro diet, from a vegetarian rice bowl to avocado chocolate brownies. A typical ratio for the macro diet is 50 percent carbs, 30 percent protein, and 20 percent fat, notes Jacqueline Gomes, RDN, MBA, a New York City-based supermarket dietitian. However, individual macro ranges for a balanced diet can fall anywhere between 45 percent to 65 percent carbohydrates, 10 percent to 35 percent protein, and 20 percent to 35 percent fat, according toThe National Academies of Science, Engineering, and Medicine guidelines.

To follow the macro diet, you'll need to do some calculations to get started. "The first step is to calculate your energy needs based on your sex, height, weight, activity, and end goalsuch as weight loss, weight maintenance, or muscle building," explains Gomes. "Macronutrient calculators, which can easily be found online, can help you calculate the macro quantities in a tailored diet plan. If your goal is weight loss, a percentage of calories is deducted from the overall maintenance calorie level to create a caloric deficit." Once you determine your ideal macronutrient breakdown, you can use a meal-planning app such as MyFitnessPal to track what you eat, as well as your daily macronutrient breakdown.

As for how hard your brain is going to work following this diet, Gomes says the diet itself is not complicated. "However, what may be complicated is building a balanced meal plan around macros with no nutrition background," she says.

"Counting macros can be effective for weight management and building muscle, as the method helps keep you close to your calorie and nutrient requirements," says Gomes. Some research shows success with specific macronutrient breakdowns. For instance, in a 2018 studyin Nutrients, researchers had older women eat a high-protein, reduced-carbohydrate diet with 30 percent of calories from fat, while also participating in a resistance-based exercise program. Compared to those following a high-carb diet, these women experienced more favorable body composition changes. "However, there is no one size fits all approach to weight management," says Gomes.

To properly adhere to the diet, you may find it useful to measure your food, either through using measuring cups and spoons, or food scalesor both. Counting macros is meant to help a person meet his or her nutrition goals from eating a variety of foods he or she loves, says Gomes. "But there's one caveat. You still have to be mindful about selecting the right foods for balanced nutrition, as it is possible to meet your macros by choosing less optimal food choices. Like any eating plan, a balanced diet on the macro diet includes a variety of fruits, vegetables, whole grains, and lean proteins."

The macro diet has other potential downsides. These include possible food obsession and stress, says Gomes. "For some people, it can become overwhelming to track all foods consumed and have them fit into a very specific number of grams of macronutrients," she says. "Eating at restaurants or a friend's home may become challenging due to the inability to accurately estimate portion sizes."

Although similar-sounding, the macrobiotic diet is completely different from the macro diet. The first thing to note about it is that it has some pretty deep roots. "It's a fad diet with roots in Zen Buddhism," says Harris-Pincus. "The goal is to create a balance in health and life, based on the yin-yang philosophy." Although the macrobiotic diet wasn't designed for weight loss, Harris-Pincus notes that some people use it for that purpose.

How do you follow the macrobiotic diet? It's a mostly plant-based diet, and it requires eating mostly whole grains, beans, and cooked vegetablesand making an effort to choose organic and locally grown foods, per the U.S. National Library of Medicine's National Center for Biotechnology Information. More specifically, about half your calories will come from organic whole grains, another quarter or so from locally grown veggies, and 5% to 10% from beans and sea vegetables, notes Harris-Pincus. "Fresh seafood, local fruit, and nuts are OK several times per week, and you can have a little rice syrup on occasion."

The list of what you can't have is longer than what you can eat. It includes dairy, eggs, poultry, meat, tropical fruit, juice, refined sugar, spicy foods, processed foods, coffee, and even certain veggies such as asparagus, eggplant, zucchini, tomatoes, and spinach, says Harris-Pincus. Examples of recipes you can eat include plain healthy roasted chickpeas and an oatmeal bowl. "In general, this diet is lower in fat and sugar," adds Amanda Blechman, RD, senior manager of scientific affairs at Danone North America at New York City.

The macrobiotic diet focuses on lifestyle habits, too. "In addition to food choices, following a macrobiotic diet often includes a component of mindfulness, such as thoroughly chewing each bite," says Blechman.

A 2015study in Nutrition and Cancer shows that following a strict macrobiotic diet may lead to greater anti-inflammatory benefits than the typical American diet. "Although this diet eliminates many animal products, it allows for limited intake of other nutritious foods like fish, fruit, and nuts," says Blechman. "This makes balanced nutrition possible with careful planning." The macrobiotic diet also tends to be low in calories while providing a high amount of nutrients. This could help with weight-loss efforts.

If you're planning to follow the macrobiotic diet, you should focus on making sure to include nutrient-rich foods. Since the diet lacks dairy, incorporating other sources of calcium, such as calcium-fortified soymilk, is important, says Blechman. "Adequate protein intake is also possible with careful planning," she says. "Fish and soy are two high-quality protein sources allowed within a macrobiotic eating plan."

As with the macro diet, the macrobiotic diet isn't without downsides. "There is not conclusive scientific evidence to support the long-term weight loss benefits of following a macrobiotic diet," says Blechman. "While the macrobiotic diet does encourage consumption of many nutritious foods, it also eliminates entire food groups. This may result in inadequate nutrient intake if your diet is not carefully planned. Restrictive diets can also be difficult for people to adhere to if favorite foods are suddenly cut out." (Also, check out the worst diet advice nutritionists ever heard.)

"Both have drawbacks," says Harris-Pincus. "Counting macros can be good for weight loss if you stick to the numbers and begin with a calorie total that will create a deficit for you. Ultimately, you need to consume fewer calories than you burn to lose weight. A macrobiotic diet may or may not help you lose weight, depending on what you choose to eat and how much."

Neither diet is easy to follow. "Both diets are labor-intensive," says Harris-Pincus. "If you don't have a lot of time in your day to shop, cook, or count, neither one may be good for you. And neither are likely to create permanent lifestyle habits for most people."

If you have to choose one, a macro diet may be more likely to get you the nutrients you need. "Counting macros is more likely to lead to a balanced diet because the whole point is balancing macronutrients," says Harris-Pincus. If you aren't a very type-A person, though, the degree to which you need to plan and track your diet may make your head spin. (Get healthy recipes for weight loss that aren't salad.)

No matter what eating plan you choosethe macro diet, the macrobiotic diet, or just a general plant-based dietmeeting with a registered dietitian nutritionist can help you make sure you're getting all the nutrients you need to lead a healthy life and meet your goals. You can find one in your area at eatright.org.

Amy Gorin is a freelance writer, a plant-forward registered dietitian nutritionist, and owner of Amy Gorin Nutrition in the New York City area. Connect with her on Pinterest, Instagram, Facebook, and Twitter.

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Macro Diet vs. Macrobiotic Diet: What's the Difference? - msnNOW


Feb 19

All the ways that diet soda is bad for you and what to drink instead – Insider – INSIDER

Just because diet soda doesn't contain sugar or calories, doesn't mean that it's healthy for you.

Studies are mixed, but some link diet soda with serious, life-threatening diseases. Here's what you need to know about diet soda and how it affects your health.

A 2017 study published in Stroke found that, among over 3,000 participants, an increase in artificially sweetened soda consumption was associated with an increased risk of Alzheimer's disease, dementia, and ischemic stroke.

Most recently, a 2019 study published in JAMA Internal Medicine, found that those who drink two diet sodas a day are more likely to die from circulatory diseases, as well as increased mortality overall, compared to those who had one diet soda or less a month.

Increased sugar cravings: Diet soda has been shown to increase cravings for sweets, according to various studies, including one published in 2019 in Pediatric Obesity. In turn, that increase in cravings may actually lead to consuming more calories.

Not effective for weight loss or diabetes: While it can seem like cutting back on sugar by replacing it with artificial sweeteners will be beneficial for weight loss or diabetes, evidence suggests otherwise. "Diet soda does not promote weight loss and it has no effect on glycemic response in adults with diabetes. Therefore, diet soda should not be used as a weight-loss strategy or means to control diabetes," says Rebecca Oh, RD, clinical dietitian at USC Verdugo Hills Hospital.

Altered digestive tract: "Diet soda can alter your gut microbiota, which can have negative impacts on digestion and hormone regulation," says Oh. More research is needed to understand exactly which artificial sweeteners affect gut bacteria and how. So far, preliminary studies have found that saccharin, sucralose, and stevia may alter the bacteria in your gut, though it's unclear what impact this may have on your health.

Kidney damage: "Long-term consumption of diet soda can increase production of free radicals in renal tissues, potentially causing damage to the kidneys," says Oh. Additionally, a 2017 study published in the Clinical Journal of the American Society of Nephrology showed that diet soda consumption is linked to a higher risk of kidney disease.

Not great for your teeth: Think diet soda is better for your teeth because it doesn't contain sugar? Think again. Even though it's sugar-free, diet soda is acidic thanks to ingredients like citric acid, phosphoric acid, citric acid, and tartaric acid. These ingredients can contribute to tooth enamel erosion, at almost the same rate as non-diet soda, according to Colgate.

Some ingredients in diet soda can be particularly harmful for people with certain health conditions. "Phosphorus should be avoided for people on dialysis and with late-stage kidney disease, and Phenylalanine is not safe for people with phenylketonuria, or PKU," says Oh.

Of course, consuming diet soda occasionally is safer than daily consumption for the average adult. "If you are going to drink a soda, drink a very small serving, 6 to 8 ounces max, and work on weaning your cravings," says Oh. She says this goes for diet soda or regular soda.

She also says that drinking soda, diet or regular, will not hydrate you as well as drinking good old-fashioned water add a spritz of lemon or lime juice for flavor.

"Rather than focus on the 'limit' of how much diet soda you can drink, I encourage you to focus on how best to promote your health. Water is the best way to hydrate your body, quench your thirst, and promote health," says Oh.

If you find it hard to drink plain water, she recommends unsweetened sparkling water or unsweetened tea over other beverage options. If you're struggling to cut diet soda out of your diet and are concerned about the health risks, speak to your primary care provider or a registered dietitian.

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All the ways that diet soda is bad for you and what to drink instead - Insider - INSIDER


Feb 19

Medical Nutrition Therapy: How It Works, Conditions, and More – Healthline

MNT is based on decades of medical research on the relationship between diet, nutrition, and health outcomes.

Its vastly different from nutrition education, which provides basic nutrition information to the general public and isnt intended to treat medical conditions.

On the other hand, MNT instructs individuals how to use their diet to best support their medical conditions. It not only addresses existing medical conditions but also attempts to lower the risk of new complications.

To start this therapy, an RDN first performs a comprehensive nutrition assessment for an individual. They then develop a nutritional diagnosis, goal, and care plan, as well as specific nutrition interventions to help the person better manage or treat their condition (2).

The RDN provides repeated follow-up visits to support the persons behavioral and lifestyle changes. This involves monitoring and evaluating progress, as well as any health or medication changes (2).

MNT is only provided by a qualified dietician and can either be prescribed in a hospital or outpatient setting. It may start during a hospital admission and continue into an outpatient setting, as long as the patient is seeing an RDN.

MNT can range in complexity, from designing a reduced calorie diet for weight loss to prescribing a high protein diet to promote wound healing for patients with severe burns.

In severe cases, such as for people with cancer, an RDN can recommend tube or intravenous (IV) feeding to prevent malnutrition.

The duration of MNT varies. Typically, the therapy stays in place until the initial goal is achieved or the nutrition-related diagnosis is resolved. However, the plan can be adjusted as needed by the RDN and your medical team.

MNT is an evidence-based nutrition therapy led by a registered dietitian nutritionist (RDN) to help treat medical conditions. It occurs in a hospital or outpatient setting and involves a comprehensive assessment, nutritional diagnosis, and treatment plan.

MNT can be a very effective component of the overall management plan for a number of common diseases.

Diabetes is a condition in which your blood sugar levels become too high. This can either be type 1, in which your pancreas produces too little insulin, or type 2, in which your body doesnt properly use insulin to regulate blood sugar (3).

If left untreated, diabetes can lead to complications like nerve and vision damage, stroke, kidney disease, poor circulation, heart disease, and gum infections (4).

Research shows that MNT can help control diabetes (1, 5, 6, 7).

For example, studies note that this therapy can lower certain markers of diabetes, such as hemoglobin A1c (HbA1c), which is an indicator of long-term blood sugar control (8, 9, 10).

Its also effective at managing gestational diabetes, a high blood sugar condition that occurs during pregnancy and requires dietary changes (11).

Treatment usually involves an RDN teaching carb counting and portion control, a technique that helps control blood sugar by keeping carb intake consistent since carbs affect blood sugar more than other nutrients (6).

Heart disease refers to several conditions that affect heart function, such as irregular heartbeat, high blood pressure, and plaque buildup in your arteries. Left untreated, it can lead to heart attack, stroke, aneurysm, heart failure, and even death (12, 13).

Research demonstrates that MNT can reduce risk factors for heart disease, such as LDL (bad) cholesterol, triglycerides, and high blood pressure (14, 15).

A dietician may recommend that you adhere to a diet low in saturated fat, cholesterol, sodium, and inflammatory foods (15). Emphasis may be placed on increasing fruits and vegetables and following a more plant-based diet.

As obesity is a risk factor for heart disease, an RDN may also encourage lifestyle changes to achieve and maintain a healthy weight, including increasing physical activity and getting adequate sleep (16).

Cancer is a disease in which abnormal cells start to divide uncontrollably. It can affect any part of your body, such as your blood, bones, or organs (17).

One of the primary reasons that a dietician may be involved in cancer treatment is to help individuals with poor appetite, which is a common symptom of chemotherapy or cancer medications (18).

Radiation therapy may also damage the gastrointestinal lining and make it painful to eat or difficult to digest foods.

As such, many people with cancer struggle to eat enough and are at risk of malnutrition. An RDN may recommend high calorie nutritional shakes or other fat- and protein-rich foods that are easy to consume and digest (18).

In severe cases, an RDN may recommend tube or IV feeding.

People with ulcerative colitis, Crohns disease, irritable bowel syndrome (IBS), and Celiac disease, as well as those whove lost part of their intestinal tract due to surgery, can all benefit from MNT (19).

These digestive ailments can lead to poor nutrient absorption, malnutrition, weight loss, a buildup of toxins in the colon, and inflammation (20).

A dietician can develop a tailored MNT plan to fit the needs of a specific digestive condition, reduce symptoms, and improve quality of life.

For example, someone with inflammatory bowel disease (IBD) may benefit from a supervised elimination diet, in which certain foods are excluded and slowly added back to their diet to identify those that trigger symptoms (21, 22).

Untreated kidney disease, in which your blood is not filtered normally, can lead to complications like high levels of calcium and potassium in the blood, low iron levels, poor bone health, and kidney failure (23, 24).

MNT is useful because most people with kidney disease may need to adjust their diet.

For example, some should limit their intake of nutrients like protein, potassium, phosphorus, and sodium, while others may need to adhere to certain fluid restrictions. These needs vary widely depending on the stage or severity of the disease (25).

Treating high blood pressure is often central to MNT for someone with kidney issues, as high blood pressure can increase your risk of this disease (26).

MNT can be used to treat numerous medical conditions, such as heart disease, diabetes, cancer, kidney disease, and digestive issues.

Like other medical treatments, MNT has an appropriate time and place.

MNT is prescribed after an in-depth evaluation by an RDN determines that you have a medical condition that can be improved by adhering to this method.

As such, MNT isnt always necessary. For example, someone admitted to the hospital for a procedure who is determined to be eating well, adequately nourished, and not at risk of malnutrition may not require MNT.

In general, a doctor orders a nutritional assessment from an RDN when a patient is admitted to the hospital. In an outpatient setting, an RDN may be consulted if a doctor suspects a nutrition-related concern.

MNT is common across various developed regions, including North America, New Zealand, Japan, and parts of Europe (27, 28, 29).

MNT is determined to be appropriate only after a thorough nutritional evaluation by a dietician in a hospital or outpatient setting.

Read the original post:
Medical Nutrition Therapy: How It Works, Conditions, and More - Healthline


Feb 19

The Sirtfood Diet: Everything you need to know – Now To Love

When Grammy Award-winning singer Adele revealed her incredible 18kg weight loss at the beginning of the year, those ready to welcome 2020 with new health and fitness goals were eager to find out just what her secret was.Along with a newfound love for Reformer Pilates, the 31-year-old also followed a Sirtfood eating plan, and when we discovered it included chocolate and red wine in its list of 'approved' foods, we'd be lying if we said it didn't pique our interest.While the keto diet re-wired how many of us think about fat with its high-fat eating plan that gained a cult following with its rapid weight loss claims, could the Sirtfood diet change how we feel about common 'treat' foods like red wine and chocolate?To find out if the Sirtfood diet is actually all about we spoke to nutritionist Michele Chevalley Hedge from A Healthy View, who gave us a rundown on the pros and cons of the eating regime.

Created by nutritionists Aidan Goggins and Glen Matten, the Sirtfood Diet is the latest diet craze to sweep the world by storm, with its creators claiming it works to turn on your body's "skinny gene".

The diet is a two-pronged approach and focuses on increasing the body's intake of sirtuin-rich foods as well as calorie restriction.

Sirtuins are a group of seven proteins which protect cells in our body from dying or becoming inflamed through illness, explains nutritionist Michele, adding research has also found the proteins can help regulate your metabolism, increase muscle and burn fat.

Sirtfoods are also particularly rich in polyphenols, says Michele, which are micronutrients packed with antioxidants which have been found to improve digestion and neurodegenerative and cardiovascular diseases.

To begin the diet, participants are expected to follow a two-week plan which includes reducing your calorie intake and consuming 'Sirtfood green juices'.

"For the first week you restrict your [calorie] intake to 1000 calories which includes consuming three sirtfood green juices and one sirtfood-rich meal a day," Michele shares.

"The following week you up your intake to 1500 calories a day and consume two sirtfood-rich meals and two green juices."

Long-term there is no specific diet, but an eating plan high in sirtfoods is encouraged along with incorporating the diet's signature green juices.

The diet's creators claim the diet will lead to rapid weight loss while maintaining muscle and mass and protecting you from chronic disease.

Wondering what that 'Signature Sirtfood Green Juice' entails? Here's the recipe.

Ingredients:Serves one

Michele says it's no surprise that people may see rapid weight loss if they're restricting their calorie intake, particularly during that first week of the diet, but says she's very wary about encouraging people to count calories.

She does, however, see a huge benefit in increasing your intake of sirtuin-rich foods, saying any diet rich in wholefoods without added sugars will be beneficial for your health.

She adds, "Sirtfoods activate fat burning, but also promote muscle growth, maintenance and repair. Eating food naturally rich in sirtuin activators may be healthier, more effective and cheaper alternative to polyphenol supplements."

Focusing on eating a balanced, sirtfood-rich diet and incorporating regular movement into your day is always a great step towards a fitter, healthier you.

The Ministry of Health recommends talking to your GP before undertaking any major changes to your diet.

Read the original post:
The Sirtfood Diet: Everything you need to know - Now To Love


Feb 19

Antibiotics in canine GI disease: when to use and when to ditch – dvm360

Ksenia / stock.adobe.com

Antibiotics are often prescribed for dogs with gastrointestinal (GI) signs. In fact, three studies surveying veterinary prescribing habits in the U.K. showed that antimicrobials were prescribed as first-choice therapy in 50% or more of dogs presenting with acute diarrhea.1-3 While antibiotics can certainly be beneficial or even lifesaving for some dogs with GI disease, for others these drugs are unnecessary and may even be harmful.

Antimicrobial resistance. As antimicrobial resistance becomes an ever-pressing concern in modern human medicine, there has been a growing movement in veterinary medicine to promote appropriate and judicious use of antibiotics.4-6 Oral administration of antibiotics may lead to the rapid development of resistant strains in the GI tract; cross-resistance to other antimicrobial agents can also occur.7

Effects on the microbiome. Opinions vary about the short- and long-term effects of antibiotics on the microbiome, which plays an important role in health and immunity, but its clear that concern is warranted (Figure 1). In one study, metronidazole was shown to cause a transient decrease in pathogenic bacteria and an increase in beneficial bacteria,8 but a different study showed that the fecal dysbiosis index was significantly increased in healthy dogs receiving metronidazole, indicating significant alterations in the microbiome structure and diversity, with some changes remaining up to 4 weeks after the completion of antibiotic administration.9 (The fecal dysbiosis index is a polymerase chain reaction [PCR] assay that quantifies the abundances of various bacterial groups, with values < 0 indicating a normal fecal microbiota and values > 0 indicating dysbiosis.)

Fenbendazole has no significant effects on the microbiome of healthy dogs, 10 but tylosin, another commonly prescribed medication for GI disease, can have prolonged effects.11 In one study, healthy dogs receiving standard doses of oral tylosin had significantly increased fecal dysbiosis indices, persisting for at least 2 months in some dogs.12 Although none of the dogs in these studies had (or developed) GI signs, the effects of antibiotics on the microbiome warrant further investigation.

Long-term consequences. While we know antibiotic use affects the microbiome, we do not know the potential long-term consequences. Links have been found in humans between antibiotic exposure early in life and the development of various diseases, such as inflammatory bowel disease and allergies.13-15 Thus, it is reasonable to be concerned that antibiotic use in our own patientsespecially young, growing dogsmight suffer similar consequences.

Uncomplicated acute diarrhea in dogs has many possible causes, but a primary bacterial etiology is uncommon. Although diarrhea is often self-limiting, antibiotics are sometimes prescribed by practitioners in an effort to expedite recovery.

Studies evaluating whether antibiotics have a discernible effect on time to resolution of diarrhea in dogs have had mixed results. One study failed to identify a significant difference in time to recovery in dogs treated with metronidazole compared with placebo,16 and another found that metronidazole hastened resolution of diarrhea by about 1.5 days (both groups in this study recovered quickly).17 A large, retrospective observational study found that dietary modification and nutraceuticals (which included probiotics) were positively associated with resolution of acute diarrhea, but no such association was found with pharmaceutical agents (including antibiotics).3

Given that there is minimal (if any) proven benefit of antibiotic use in dogs with uncomplicated acute diarrhea, there is no basis to support the routine prescription and use of antibiotics in these cases.

Canine parvovirosis has a tropism for rapidly dividing cells, including those of the intestinal crypt epithelium, which leads to a severe enteritis. This, paired with the neutropenia that classically occurs with this disease, places patients at risk for bacterial and endotoxin translocation, which can result in bacteremia, systemic inflammatory response syndrome (SIRS) or multiorgan dysfunction. For this reason, broad-spectrum antibiotics are warranted in neutropenic patients suffering from canine parvovirus infection.

Typically, a beta-lactam antibiotic (ampicillin 22 mg/kg IV three times daily) is used, alone or in conjunction with enrofloxacin (5-10 mg/kg/day IV); see Table 1. Enrofloxacin may cause cartilage damage in young, growing animals, but this is rare with standard doses. Aminoglycosides can also be considered in well-hydrated dogs, but its use carries a risk of acute renal failure.

Table 1. Indications, antibiotic agents, and doses for treating GI disease in dogs

Acute hemorrhagic diarrhea syndrome (AHDS), formerly known as hemorrhagic gastroenteritis, is associated with a small intestinal overgrowth of Clostridium perfringens,18 although it should be noted that this organism is present consistently in the feces of healthy dogs. The netF toxin gene produced by C. perfringens might play an important role in the pathogenesis of this disease. Although there is no significant difference in C. perfringens encoding for the alpha toxin or enterotoxin between dogs with AHDS, parvovirus, or healthy controls, a significantly greater number of dogs with AHDS have the netF toxin gene.19 While the presence of netF gene in fecal samples supports C. perfringensassociated AHDS, there is no difference in outcome between netF-positive and netF-negative dogs. It should also be noted that there is a 10% to 12% prevalence of this gene in nonspecific diarrhea cases and healthy controls, and about 50% of dogs with AHDS are netF negative.

There is no significant difference in the recovery and outcome of dogs treated with or without amoxicillin/clavulanic acid,20 and in a study evaluating the effects of a probiotic on the clinical course of AHDS, dogs made a rapid recovery without antibiotics.21 For this reason, unless evidence of sepsis exists (such as fever or toxic change of neutrophils on a leukogram), antimicrobials are unlikely to be necessary for the treatment of this syndrome.

Dogs with AHDS that do not receive antibiotics have a good prognosis and rapid recovery, despite roughly one-third of these patients meeting two or more SIRS criteria.22 This suggests that standard SIRS criteria alone may not be strict enough to guide appropriate use of antimicrobials.

Antibiotic-responsive diarrhea (ARD) describes a chronic (> 3 weeks) enteropathy for which no underlying cause is found and which is completely responsive to antibiotic treatment. Classically, ARD is seen in young, large-breed dogs, with German shepherds being overrepresented. It is characterized by chronic intermittent diarrhea as well as weight loss, a variable appetite, and possible vomiting.

The diagnosis is based on a positive response to therapy, exclusion of other diseases (e.g. exocrine pancreatic insufficiency in a young German shepherd with weight loss and diarrhea) and a demonstration of disease relapse when antibiotics are withdrawn. Excluding other diseases is important as many of them may improve temporarily with antibiotics; thus a positive response to therapy does not negate the need for appropriate workup.

About two-thirds of dogs with chronic enteropathies have food-responsive enteropathies, with ARD and steroid-responsive diarrhea making up the remaining third.23,24 Dogs with food-responsive diarrhea have better outcomes than dogs with either ARD or steroid-responsive disease. Therefore, an antibiotic trial should be considered only after a strict diet trial (hydrolyzed protein or novel protein diet) for a minimum of 3 weeks with no response.23

The antibiotics recommended for treatment of ARD are metronidazole (10-15 mg/kg PO twice daily) and tylosin (25 mg/kg PO once or twice daily). Some dogs respond specifically to tylosin,25 so it may make more sense to look to tylosin before metronidazole in an antibiotic trial for a chronic enteropathy. Response to therapy should be quick (within 2 weeks), and dogs with a positive response to tylosin at 25 mg/kg/day might respond to doses as low as 5 mg/kg/day.26 Thus, dose reduction can be considered following a positive response to the standard dose.

As noted earlier, ARD is definitely diagnosed when relapse occurs following antibiotic withdrawal and clinical signs resolve when the antibiotic is re-introduced.27 That said, not all dogs require lifelong therapy and periodic withdrawal of antibiotics should be attempted to determine whether ongoing therapy is necessary.

Escherichia coliassociated granulomatous colitis is characterized histologically by granulomatous inflammation with periodic acid-Schiffpositive macrophages. This disease classically is seen in young boxer dogs or French bulldogs.28 Patients usually present with a combination of colitis, hematochezia and weight loss.

With the use of fluorescence in situ hybridization (FISH; Figure 2), mucosally invasive E. coli was identified as the likely cause of this disease. Long-term remission is associated with eradication of the bacteria.29,30 Typically, it is treated with a long course of fluoroquinolones, such as enrofloxacin (5-10 mg/kg/day for six to eight weeks). This disease has been identified in a variety of other breeds and even in cats, with reported remission with fluoroquinolone therapy.31 However, resistance of E. coli to fluoroquinolones has been demonstrated. Therefore, bacterial culture and sensitivity testing of the tissue is recommended. Due to the potential for the development of antimicrobial resistance, empiric therapy for this disease is not recommended.

Enteropathogenic bacteria (and/or their toxins) are often detected today using fecal PCR panels, which allow for the identification of organisms such as Clostridium difficile, C. perfringens, Campylobacter spp. and Salmonella spp., among others. An ACVIM consensus article regarding enteropathogenic bacteria offers a more detailed discussion on this topic.6

As these organisms can be found in both healthy animals and in those with diarrhea, interpretation of the results of these panels can be confusing. For some organisms, identification of enterotoxin genes may be more helpful. Enterotoxin genes are produced by both C. perfringens and C. difficile and are found more frequently in dogs with diarrhea than in those without.

Clinically, many of these cases will present as self-limiting diarrhea that does not require antimicrobial therapy. In fact, overuse of antibiotics in these scenarios may promote drug-resistant organisms.

Conversely, if a patient presents with systemic signs of illness (e.g. fever, toxic changes or a degenerative left shift) and is diagnosed with an enteropathogenic bacteria, appropriate antibiotic therapy may be warranted.

Despite the zoonotic potential of Salmonella and Campylobacter spp., antimicrobial therapy is not indicated in nonclinical or mildly affected dogs. This recommendation remains the same even with an immunocompromised owner. In this case, appropriate husbandry and hygiene become the more important aspects of management.

Despite the frequency of antibiotic use for GI disease in dogs, there are relatively few indications for prescribing antimicrobials in this context (Table 2). Overuse could result in antimicrobial resistance and may have long-reaching effects on the host microbiome. Therefore, in the absence of evidence to support their use, antibiotics should be avoided in systemically healthy animals. For systemically ill animals, clinical judgment should be used until more specific criteria are developed.

Table 2. When to use (or avoid) antibiotics

References

1. German AJ, Halladay LJ, Noble PJ. First-choice therapy for dogs presenting with diarrhoea in clinical practice. Vet Rec 2010;167:810-814.

2. Jones PH, Dawson S, Gaskell RM, et al. Surveillance of diarrhoea in small animal practice through the Small Animal Veterinary Surveillance Network (SAVSNET). Vet J 2014;201:412-418.

3. Singleton DA, Noble PJM, Sanchez-Vizcaino F, et al. Pharmaceutical prescription in canine acute diarrhoea: a longitudinal electronic health record analysis of first opinion veterinary practices. Front Vet Sci 2019;6:218.

4. Lappin MR, Blondeau J, Boothe D, et al. Antimicrobial use guidelines for treatment of respiratory tract disease in dogs and cats: Antimicrobial Guidelines Working Group of the International Society for Companion Animal Infectious Diseases. J Vet Intern Med 2017;31:279-294.

5. Weese JS, Blondeau J, Boothe D, et al. International Society for Companion Animal Infectious Diseases (ISCAID) guidelines for the diagnosis and management of bacterial urinary tract infections in dogs and cats. Vet J 2019;247:8-25.

6. Marks SL, Rankin SC, Byrne BA, et al. Enteropathogenic bacteria in dogs and cats: diagnosis, epidemiology, treatment, and control. J Vet Intern Med 2011;25:1195-1208.

7. Schmidt VM, Pinchbeck G, McIntyre KM, et al. Routine antibiotic therapy in dogs increases the detection of antimicrobial-resistant faecal Escherichia coli. J Antimicrob Chemother 2018;73:3305-3316.

8. Igarashi H, Maeda S, Ohno K, et al. Effect of oral administration of metronidazole or prednisolone on fecal microbiota in dogs. PLoS One 2014;9:e107909.

9. Suchodolski JS, Olson E, Honneffer J, et al. Effects of hydrolyzed protein and metronidazole on the fecal microbiome and metabolome in healthy dogs. J Vet Intern Med 2016;30:1407-1519.

10. Fujishiro MA, Lidbury JA, Pilla R, et al. Evaluation of the effects of anthelmintic administration on the fecal microbiome of healthy dogs with and without subclinical Giardia spp. and Cryptosporidium canis infections. PLoS One 2020;15:e0228145.

11. Suchodolski JS, Dowd SE, Westermarck E, et al. The effect of the macrolide antibiotic tylosin on microbial diversity in the canine small intestine as demonstrated by massive parallel 16S rRNA gene sequencing. BMC Microbiol 2009;9:210.

12. Manchester AC, Webb CB, Blake AB, et al. Long-term impact of tylosin on fecal microbiota and fecal bile acids of healthy dogs. J Vet Intern Med 2019;33:2605-2617.

13. Kronman MP, Zaoutis TE, Haynes K, et al. Antibiotic exposure and IBD development among children: a population-based cohort study. Pediatr 2012;130:e794-803.

14. Ni J, Friedman H, Boyd BC, et al. Early antibiotic exposure and development of asthma and allergic rhinitis in childhood. Pediatr 2019;19:225.

15. Ungaro R, Bernstein CN, Gearry R, et al. Antibiotics associated with increased risk of new-onset Crohn's disease but not ulcerative colitis: a meta-analysis. Am J Gastroenterol 2014;109:1728-1738.

16. Shmalberg J, Montalbano C, Morelli G, et al. A randomized double blinded placebo-controlled clinical trial of a probiotic or metronidazole for acute canine diarrhea. Front Vet Sci 2019;6:163.

17. Langlois DK, Koenigshof AM, Mani R. Metronidazole treatment of acute diarrhea in dogs: A randomized double blinded placebo-controlled clinical trial. J Vet Intern Med 2019;34:98-104.

18. Unterer S, Busch K, Leipig M, et al. Endoscopically visualized lesions, histologic findings, and bacterial invasion in the gastrointestinal mucosa of dogs with acute hemorrhagic diarrhea syndrome. J Vet Intern Med 2014;28:52-58.

19. Sindern N, Suchodolski JS, Leutenegger CM, et al. Prevalence of Clostridium perfringens netE and netF toxin genes in the feces of dogs with acute hemorrhagic diarrhea syndrome. J Vet Intern Med 2019;33:100-105.

20. Unterer S, Strohmeyer K, Kruse BD, et al. Treatment of aseptic dogs with hemorrhagic gastroenteritis with amoxicillin/clavulanic acid: a prospective blinded study. J Vet Intern Med 2011;25:973-979.

21. Ziese AL, Suchodolski JS, Hartmann K, et al. Effect of probiotic treatment on the clinical course, intestinal microbiome, and toxigenic Clostridium perfringens in dogs with acute hemorrhagic diarrhea. PLoS One 2018;13:e0204691.

22. Moberg FS, Bjornvad CR, Lorentzen C, et al. Dogs with acute haemorrhagic diarrhoea syndrome not receiving antibiotics have a good prognosis despite initial high AHDS-score and systemic inflammation. Presented at the 29th European College of Veterinary Internal MedicineCompanion Animals Congress, September 2019.

23. Volkmann M, Steiner JM, Fosgate GT, et al. Chronic diarrhea in dogs - retrospective study in 136 cases. J Vet Intern Med 2017;31:1043-1055.

24. Allenspach K, Culverwell C, Chan D. Long-term outcome in dogs with chronic enteropathies: 203 cases. Vet Rec 2016;178:368.

25. Westermarck E, Frias R, Skrzypczak T. Effect of diet and tylosin on chronic diarrhea in beagles. J Vet Intern Med 2005;19:822-827.

26. Kilpinen S, Spillmann T, Westermarck E. Efficacy of two low-dose oral tylosin regimens in controlling the relapse of diarrhea in dogs with tylosin-responsive diarrhea: a prospective, single-blinded, two-arm parallel, clinical field trial. Acta Vet Scand 2014;56:43.

27. Kilpinen S, Spillmann T, Syrja P, et al. Effect of tylosin on dogs with suspected tylosin-responsive diarrhea: a placebo-controlled, randomized, double-blinded, prospective clinical trial. Acta Vet Scand 2011;53:26.

28. Manchester AC, Hill S, Sabatino B, et al. Association between granulomatous colitis in French bulldogs and invasive Escherichia coli and response to fluoroquinolone antimicrobials. J Vet Intern Med 2013;27:56-61.

29. Mansfield CS, James FE, Craven M, et al. Remission of histiocytic ulcerative colitis in boxer dogs correlates with eradication of invasive intramucosal Escherichia coli. J Vet Intern Med 2009;23:964-969.

30. Craven M, Mansfield CS, Simpson KW. Granulomatous colitis of boxer dogs. Vet Clin North Am Small Anim Pract 2011;41:433-445.

31. Leal RO, Simpson K, Fine M, et al. Granulomatous colitis: more than a canine disease? A case of Escherichia coli-associated granulomatous colitis in an adult cat. JFMS Open Rep England: 2017:2055116917731168.

Author disclosure: Dr. Lidbury is affiliated with the Gastrointestinal Laboratory at the Texas A&M University that offers the canine fecal dysbiosis index and fecal enteropathogen testing on a fee-for service basis.

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Antibiotics in canine GI disease: when to use and when to ditch - dvm360



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