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Consumer Reports reviews Contrave weight loss pill – KOMO News
by Consumer Reports and Connie Thompson
Contrave weight loss pills (Photo: Screen shot from website)
You may have seen the television commercials for the prescription weight-loss pill Contrave.
Contrave is the combination of two older drugs: the antidepressant bupropion and the addiction-treatment drug naltrexone.
Its ads say the drug works on the brain to reduce hunger and control cravings. The Food and Drug Administration approved Contrave is for people with a body mass index of 27 or higher and who also suffer from serious conditions, such as heart disease, high blood pressure, high cholesterol or type-two diabetes.
The commercial cites studies in which patients took Contrave in addition to diet and exercise. The patients lost approximately two to four times more weight than those who did diet and exercise alone.
However, a Consumer Reports analysis of the three clinical trials used to gain FDA approval of the drug shows the drug works but the amount of additional weight loss is small and could pose serious health risks.
In addition to anxiety, insomnia and headaches, Contrave can cause serious health problems, such as liver damage, seizures, increased blood pressure and possible heart risks.
The people who took it up to 56 weeks lost only five to nine pounds more on average than those who took a placebo.
Consumer Reports advises consumers to speak with their doctor about the risks and different weight-loss options. Consumer Reports health experts say it is best to lose weight the safer, proven way - by eating less and exercising.
If you've been unable to lose weight on your own, ask your doctor about intensive behavioral programs that have at least 12 sessions a year and include multiple strategies to help you switch to a healthier diet and increase physical activity.
Manufacturer's response
I reached out to the makers of Contrave for their comments on Consumer Reports' analysis.
I received the following response from a representative at Orexigen Therapeutics:
Consumer Reports is an outstanding service to the American public but, as a representative of Orexigen Therapeutics, we believe there area few key areas that may be missing some data and context.
From a data perspective, Contrave has a well-studied safety and tolerability profile. The efficacy results presented in the Consumer Reports article focus on the intention-to-treat population data, including patients who discontinued study medication and non-responders.
Our mission, and what drives the actions we take as an organization, is to help improve the health and lives of patients struggling to lose weight.
People who are overweight or obese often blame themselves for having a lack of willpower or discipline to lose weight. While diet and exercise are crucial and fundamental components of any weight management plan -diet and exercise alone doesnt work for everyone. We now understand that the brain plays a role in weight loss as it controls hunger and cravings. Contrave, which is believed to work on the hunger and cravings centers of the brain, is an FDA approved weight loss medication to be used in combination with diet and exercise.
It is a combination of two medicines that have been used clinically for decades. With over 10 years of clinical development experience and over 10,000 patients studied in clinical trials we have a very clear understanding of the risk-benefit profile of Contrave.
Medical weight-loss may not be appropriate for everyone, but with about 110 million adults who are obese or overweight in the US population we believe Contrave represents an important therapeutic tool to put in the hands of physicians. We want patients to engage with physicians to discuss what works best for them.
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Consumer Reports reviews Contrave weight loss pill - KOMO News
Emma Thompson Reacts to Fat-Shaming – AARP News
Although Thompson didnt name the costar, she did say she confronted producers over the request.
There was a wonderful actress I was working with on Brideshead Revisited, and the producers said, Will you lose some weight? the two-time Oscar winner recalled. And she was absolutely exquisite.
And I said to them, If you speak to her about this again on any level, I will leave this picture. You are never to do that. Its evil whats going on out there, and its getting worse, she added.
In addition to Thompson, the 2008 film also starred Hayley Atwell, who confirmed Thompsons story in 2008.
I went round to Emmas one night and she was getting very angry that I wasnt eating all the food she was giving me, Atwell said. I told her why, and she hit the roof.
In the interview with Skavlan, Thompson joked that Hollywoods obsession with being thin has kept her from living there.
I never moved to the U.S. I couldnt. Every time I have to go to Los Angeles I think, Oh, God, Im too fat to go there, theyre not going to let me in, she said. I think they are saying to me when I arrive, You are fat, and you are old. Go home.
Thompson also doesnt mince words when it comes to the French fashion industry.
The French fashion industry said they would get rid of size 0, and then, you know, they didnt. The anorexia theres so many kids, girls and boys now, and actresses who are very, very thin into their 30s, who simply dont eat, she said. They dont eat. Sometimes there are just some subjects that you absolutely have to make noise about, because its so tedious and its gone on and on.
Thompson has a reputation for being protective of younger actors. In an interview with Good Housekeeping in 2007, Kate Winslet, who starred with her friend Thompson in 1995s Sense and Sensibility, said, Emma Thompson told me, If you ever lose weight, I will never talk to you again.
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Emma Thompson Reacts to Fat-Shaming - AARP News
Emma Thompson once threatened to quit filming after producers asked her co-star to lose weight – New York Daily News
NEW YORK DAILY NEWS
Wednesday, March 29, 2017, 8:40 AM
Emma Thompson has seen a lot of body-shaming in Hollywood.
The actress revealed that she once threatened to quit a movie she was working on after overhearing producers telling her "exquisite" co-star to lose weight.
"There was a wonderful actress in a film I did called 'Brideshead Revisited,'" she said of the 2008 production. "The producer said to her, 'Will you lose some weight?' And she was absolutely exquisite!"
Thompson, 57, was discussing the mistreatment of women on set on the Swedish talk show "Skavlan" last week.
Emma Thompson says President Trump once asked her out
"I said to them, 'If you speak to her about this again, on any level, I will leave this picture. You are never to do that,'" she told the host.
The longtime actress went on to discuss how prevalent anxiety is still in the world, especially with actresses.
"The anorexia there's so many kids, girls and boys now, and actresses who are very, very thin into their 30s, who simply don't eat. They don't eat ... Sometimes there are just some subjects that you absolutely have to make noise about because it's so tedious and it's gone on and on," she continued.
She even had a few words for anyone ready to judge her appearance:
SEE IT: Disney's Beauty and the Beast trailer with Emma Watson
"Sorry, do you want me to be an actress or a model?"
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Emma Thompson once threatened to quit filming after producers asked her co-star to lose weight - New York Daily News
Five ways your life will change when you lose weight – Florida Today
DR. AYOTUNDE ADEYERI, USA TODAY NETWORK-NEW JERSEY 9:56 a.m. ET March 28, 2017
Exercise is one of the secrets to losing weight.(Photo: Getty Images)
Spring is here, and you may have kept that New Years resolution to drop some extra weight. If you did, congratulations! Your accomplishment is no easy feat, whether you lost 10 pounds or 100 pounds.
Considering nearly one in three Floridians is obese, many people may be in the midst of trying to lose 30 pounds or more this year.
With summer on the horizon, you may be motivated more than ever to continue working toward a healthier version of yourself.
Besides looking and feeling better, your overall quality of life is improving as you defeat the disease of obesity.
Im a bariatric surgeon in central New Jersey and deal with people battling very significant weight challenges.
Clevens: Nose job boosts students self esteem
Over the years, patients have consistently reported these benefits during their journeys back a normal BMI:
Food will not rule your life: Once obesity sets in, life is about food, first and foremost. But once you get a healthy nutrition pattern in place, you are no longer focused on your next snack. Youll realize that food isnt really your best friend, it just keeps you alive and gives you fuel to function.
You dont need the crutch of food to manage lifes challenges of daily life.
Youre going to feel so much better: Preparation is the number one key to weight loss success. By now, you have probably dumped the junk food, the sugar products and empty carbs out of your home and your diet. Your body doesnt need artificially processed foods (nor does your family).
Did you notice a week or two after you banished these empty calories from your diet that you no longer craved them? Thats your body thanking you for ridding it of these kinds of addictive toxins.
You are going to feel so much better once you lose weight.(Photo: Getty Images)
Get inspiration from online articles, blogs, magazines and books about healthy living. Prepare your body and your mind to make changes toward living a healthier lifestyle.
Your social circle will expand: Since you look better on the outside and feel more confident on the inside, youll be more inclined to go out and socialize more often.
You can also expand your friendship network perhaps you joined a Zumba class or started swimming. From a neighbor to go to Weight Watchers meetings with, to speed walking with a friend you dont see often enough, you can make your life richer while you get healthy.
You will inspire others: Having the courage and fortitude to lose weight is empowering and the people around you will notice. Granted, some people could even be a little envious of your weight loss, but most will be inspired and impressed. Bask a little in the positive attention youve worked hard for it.
You will actually enjoy exercise: I tell every patient that the biggest secret to losing weight and keeping it off is exercise. This effort requires as few as 30 minutes daily and you should try to break a sweat by the time you are finished. (Check with your doctor if you are very overweight or have other medical issues.)
Pamper Your Mind: Getting motivated to spring clean
Its your race to win
Regardless of how many clothing sizes you hope to drop, you are ultimately calling all the shots. Ready to rev up your weight loss? Focus on physical activity to boost metabolism, lose inches and improve the quality of your sleep. It also will maximize damage control when you indulge now and then.
Discover fitness activities that you enjoy start with walking around the neighborhood, jog/walk on a treadmill while you watch your favorite TV show, or play ball with your kids (they will be elated, I assure you). Have you always wanted to hike? Take a water aerobics class? Try yoga or Zumba?
The battle against the disease of obesity is often in the mind. When you see the physical changes happening, your mental outlook will improve as well.
Seize that momentum and go after your goals with everything youve got. Its well worth the effort.
Dr. Ayotunde Adeyeri is a board-certified advanced laparoscopic, bariatric and general surgeon on staff at several central New Jersey hospitals. He is the medical director of Sterling Surgicare in Holmdel; medical director of the Institute for Weight Loss, Raritan Bay Medical Center; and co-medical director of Central Jersey Bariatrics, Freehold. Visit SterlingSurgicare.com or call 732-217-3897.
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Five ways your life will change when you lose weight - Florida Today
5 Ways to Lose Weight and Eat Well With Cauliflower – The Daily Meal
Whether its riced, mashed, or turned into a pizza crust, cauliflower is, without-a-doubt, one of the trendiest vegetables in the produce aisle. Its subtle yet distinct taste, robust nutritional profile, and ease of preparation has escalated the cruciferous vegetable to almost cult status a reputation it largely deserves.
Click here for the Healthy Food Swaps Slideshow.
White cauliflower contains a cornucopia of vitamins and minerals such as folate and vitamins B6, C, and K, as well as isothiocyanate, a phytochemical compound which has been linked to the destruction of certain cancer cells. However, to fully take advantage of cauliflowers health properties, avoid boiling it which neutralizes a large proportion of the phytochemicals and try steaming, simmering, or roasting it instead.
A head of cauliflower can stand in as a side dish for a group of four, but it can also play a starring role. At less than 150 calories per head, using cauliflower in place of potatoes, chicken wings, or chickpeas can dramatically reduce the calorie counts of your favorite foods.
Here are five cauliflower recipes that will help you get that summer beach body.
Buffalo Cauliflower Bites
Saucy, sweet, and spicy chicken wings are so satisfying that we often risk stained hands (and shirts) to eat them. But chicken wings are often fried before theyre coated in Buffalo sauce. Using roasted cauliflower tossed in a homemade Buffalo sauce cuts down the calorie count, preserves the classic taste, and best of all, can be eaten with a fork!
Click here for the Buffalo Cauliflower Bites recipe.
Cauliflower No-Bean Hummus
Hummus comes in many shapes and forms, but this recipe is especially innovative. Steamed cauliflower takes the place of chickpeas, and is paired with a cup of cashews to add some depth and texture to the dip. Eat this one with some celery or carrot sticks, or use it as an accompanying condiment for a roasted vegetable wrap.
Click here for the Cauliflower No-Bean Hummus recipe.
Mashed Cauliflower
Simple carbohydrates can be your mouths best friend, but your bellys worst enemy. Potatoes, although nutritious, are dense and calorie-laden. Swapping in cauliflower makes for a lighter and more nutritious side dish, with one serving clocking in at less than 200 calories.
Click here for the Mashed Cauliflower recipe.
Roasted Curry Cauliflower Soup
When roasted, cauliflower develops a sweet nuttiness that complements bold spices like curry powder. Cauliflowers texture also makes it an ideal candidate for pures and soups. This roasted cauliflower soup is light enough for a spring lunch, but warm enough for a late-March evening.
Click here for the Roasted Curry Cauliflower Soup recipe.
Roasted Cauliflower With Whipped Goat Cheese
A perfectly roasted head of cauliflower is an elegant dinner table centerpiece. Tenderize the cauliflower before roasting by simmering it in an aromatic broth of wine, lemon juice, butter, sugar, bay leaf, and red pepper flake for around 20 minutes (or until it can be easily pierced with a knife). Afterwards the head is roasted until browned. An accompanying dipping bowl of whipped goat cheese with minced garlic, sea salt, and a drizzle of olive oil adds the right hint of acidity and creaminess to the cauliflower.
Click here for the Roasted Cauliflower With Whipped Goat Cheese recipe.
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5 Ways to Lose Weight and Eat Well With Cauliflower - The Daily Meal
Can eating the same meals every day help you lose weight? – TheHealthSite
As boring as it may sound, it can surely help you lose weight.
The most difficult part of going on a diet is planning daily meals that match the plan that your expert has chalked out for you. Most people give up dieting because they are unable to make new things each day and eat right. Cooking a different meal every day is too much work especially when you have to cook healthy food. But if you want to lose weight, you cannot ignore the option of eating right. So what if you could eat the same meal every day and still lose weight.
Eating the same meal every day isnt boring. It is convenient. When you start eating the same thing every day, you know what to expect at each meal and hence the craving or desire for something different is curbed down. You dont imagine what might be prepared for dinner tonight because you already know. If you can keep the temptation for eating junk or unhealthy food away, and stick to healthy food, it will certainly help you lose weight. You can also follow this sample weight loss plan by our expert dietitian.
Ms Shalini Arvind, Chief Dietician, Fortis Hospital, BG Road, Bangalore suggests eating a healthy meal every day and it can be the same food. A healthy meal consists of food from all food groups in a balanced proportion. It can either help in putting on weight, maintain weight or reduce the weight as the need be. It is the portion size, the type of food and the method of cooking that decides the end result. Thus, a healthy diet designed for reducing weight when taken on a daily basis will definitely help in weight loss but the role of exercise also is indispensable. Read: Foods and nutrients required for a balanced diet.
All you need to do is be careful of what you eat. Keep a track of your calorie intake along with the calories burnt. The idea is to not have a cheat day for at least a fortnight or month if possible.
Image Source: Shutterstock
Published: March 29, 2017 11:31 am
Disclaimer: TheHealthSite.com does not guarantee any specific results as a result of the procedures mentioned here and the results may vary from person to person. The topics in these pages including text, graphics, videos and other material contained on this website are for informational purposes only and not to be substituted for professional medical advice.
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Can eating the same meals every day help you lose weight? - TheHealthSite
Does Contrave actually help you lose weight? – WSAW
Controlling cravings and suppressing hunger have been big challenges for people trying to lose weight. A prescription weight loss pill called Contrave claims it can help with both of those things.
But the experts at Consumer Reports warn that weight loss medication can come with some major health risks.
Contrave, which has been featured in commercials on TV, is the combination of two older drugs: the antidepressant bupropion and the addiction-treatment drug naltrexone.
Its ads state the drug works on the brain to reduce hunger and control cravings. The FDA approved Contrave is for obese people or people who are overweight with a body mass index of 27 or higher.
It's also approved for those who suffer from serious conditions such as heart disease, high blood pressure, high cholesterol or type 2 diabetes.
The commercial cites studies in which patients who took Contrave along with diet and exercise lost approximately two to four times more weight than those who did diet and exercise alone.
However, a Consumer Reports analysis of the three clinical trials used to gain FDA approval of the drug showed that while the drug works, the amount of additional weight loss was small and could pose serious health risks.
"Contrave can cause anxiety, insomnia and headaches. But also serious health problems such as liver damage, seizures, increased blood pressure and possible heart risks," said Ginger Skinner, with Consumer Reports.
Consumer Reports found that people who took Contrave up to 56 weeks lost only five to nine pounds more on average than those who took a placebo. Consumer Reports health experts said it's best to lose weight the safer, proven way, by eating less and exercising.
If you've been unable to lose weight on your own, ask your doctor about intensive behavioral programs that have at least 12 sessions a year and multiple strategies to help you eat better and exercise more.
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Does Contrave actually help you lose weight? - WSAW
How 6 Women Used Cheat Meals To Help Them Lose Weight – Women’s Health
Women's Health | How 6 Women Used Cheat Meals To Help Them Lose Weight Women's Health Since vowing to never eat a burrito (or any carb ever) again ends in diet frustration and bingeing, taking a planned break from clean eating can help you lose weight without hating life. Whether you call it a cheat meal, day off, or just "cheeseburger ... |
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How 6 Women Used Cheat Meals To Help Them Lose Weight - Women's Health
How Getting A Dog Helped Me Lose 10 Pounds – Hollywood Life
Hollywood Life | How Getting A Dog Helped Me Lose 10 Pounds Hollywood Life I have been doing Weight Watchers, and the two combined have resulted in me losing 10 pounds in about 2 months! I haven't gone to the gym more than 5 times in those 2 months (whoops) but Parker is seriously keeping me on my toes and my step count ... |
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How Getting A Dog Helped Me Lose 10 Pounds - Hollywood Life
Will Intermittent Fasting Help Me Lose Weight? | POPSUGAR Fitness – POPSUGAR
POPSUGAR | Will Intermittent Fasting Help Me Lose Weight? | POPSUGAR Fitness POPSUGAR After six months of CrossFit, five days a week, my transformation wasn't as dramatic or amazing as I had hoped. I didn't get insanely ripped as planned |
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Will Intermittent Fasting Help Me Lose Weight? | POPSUGAR Fitness - POPSUGAR