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Top herbs in sports nutrition – Nutritional Outlook
When it comes to herbs with applications in sports nutrition, the skys the limit. However, given the plethora of options, Im going to limit my discussion to three evidence-based herbs: ashwagandha, citrus bergamot, and shilajit.
Ashwagandha Extract
Ashwagandha (Withania somnifera) is an extremely popular adaptogenic herb in the dietary supplement industry and has been used in Ayurvedic medicine1 for over 3,000 years. Specific to sports applications, studies have shown that ashwagandha extract may be capable of increasing testosterone levels in men by about 15%-17%.2,3,4 This is significant given testosterones well-established role in building and maintaining muscle. Additional research has also shown that ashwagandha extract may increase muscle size and strength more than exercise alone, while helping to reduce body fat percentage by double compared to exercise alone.4 Likewise, ashwagandha extract has been successfully tested5 to enhance cardiorespiratory endurance (measured as maximal oxygen uptake, or VO2max) and improve self-assessed quality of life in healthy athletic adults. These cited benefits only scratch the surface of the expansive body of research on the health, wellness, and fitness value of ashwagandha extract.
Citrus Bergamot
Overwhelming scientific evidence indicates that bergamot polyphenolic fractions (BPF) from citrus bergamot fruit are responsible for the majority of the botanicals pharmacological effects.6 Among these effects is increasing nitric oxide (NO) levels which has value in the world of sports since NO can impact muscular pump, a term used in bodybuilding circles to describe the sensation of tight congestion, or swelling, of your muscles with blood coursing through them during weight-training sessions.7
A randomized, placebo-controlled study8 evaluated the effects of 4 weeks of BPF supplementation (650 mg twice a day for 4 weeks) on serum NO and other parameters. Results were that BPF significantly increased baseline NO levels and VO2max.
Shilajit
Also part of the Ayurvedic tradition, shilajit is an exudate secreted from sedimentary rocks (largely in the Himalayas) composed of rock humus and organic substances that have been compressed by layers of rock mixed with marine organisms and microbial metabolites.9 Shilajit has been shown in research10 to increase testosterone levels by 20.45% and free testosterone by 19.4%, increase exercise time by 9%-13%,11 and increase levels of adenosine triphosphate (ATP; the bodys energy currency) by 14%12 in healthy active volunteers.
Conclusion
While there are many excellent herbs which can be used in sports nutrition, ashwagandha extract, citrus bergamot, and shilajit are three of the very best, with solid scientific evidence to support their benefits for promoting fitness applications.
About the author
Gene Bruno, MS, MHS, RH (AHG), is a certified nutritionist and registered herbalist with more than 40 years of dietary supplement industry experience. With a masters degree in nutrition and a second masters degree in herbal medicine, he has a proven track record of formulating innovative, evidence-based dietary supplements. Bruno currently serves as both the vice president of scientific and regulatory affairs at NutraScience Labs (Farmingdale, NY) and professor of nutraceutical science at Huntington University of Health Sciences.
References
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Top herbs in sports nutrition - Nutritional Outlook
Androgen Replacement Therapy Market to Grow Massively at a CAGR of 7.8% by 2030: Coherent Market Insights | – EIN News
Androgen Replacement Therapy Market Analysis
Androgen replacement therapy or low testosterone therapy is commonly called as hormone replacement therapy for men.
Androgen Replacement Therapy Market Size is estimated to Reach US$ 3,317.6 Million at a CAGR of 7.8% by 2030
Androgen replacement therapy (ART), often referred to as testosterone replacement therapy (TRT), is a form of hormone therapy, in which androgens, often testosterone, are replaced. ART is often prescribed to counter the effects of male hypogonadism.
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The report provides understandings regarding the beneficial opportunities in the Androgen Replacement Therapy Market at the country level. The report also includes a , , , , of the major key players globally for the projected period.
The inclusive report focuses on primary sections such as , , , . The segments provide details in terms of various viewpoints such as end-use industry, product or service type and any other relevant segmentation as per the markets current scenario which includes various aspects to perform further promotion activity.
Androgen Replacement Therapy Market Competitive Landscape
The market report lists the major players involved in the Androgen Replacement Therapy Market under the competitive landscape and company profile chapters. The major players in the market are evaluated based on their product and/or service offerings, financial statements, key developments, strategic approach to the market, position in the market, geographical saturation and other key landscapes. The chapter also highlights the , , ( ), winning imperatives, current focus and strategies, and threats from competition for the top players in the market.
Key Players in Androgen Replacement Therapy Market
AbbVie, Inc., Bayer AG, Endo Pharmaceuticals, Plc., Eli Lilly and Company, Kyowa Kirin International Plc., Novartis International AG, Pfizer Inc., Clarus Therapeutics, Inc., Perrigo Company Plc, Acerus Pharmaceuticals Corporation, Sawai pharmaceutical Co., Ltd., Reddy's Laboratories, Sun Pharmaceutical Industries Ltd., and Simple Pharma.
Androgen Replacement Therapy Market Segmentation
By Product Type:Testosterone Creams/Gels, Testosterone Patches, Testosterone Injections, Testosterone Implants, Testosterone Tablets/Capsules/Gums
By Active Ingredient Type:Testosterone, Methyl Testosterone, Testosterone Undecanoate, Testosterone Enanthate, Testosterone Cypionate
By Distribution Channel:Hospital Pharmacies, Retail Pharmacies, Online Pharmacies
Research Methodology
The report includes first-hand information collected from key stakeholders through quantitative and qualitative analyses based on the parameters of the Porter Five Force model. The report highlights macroeconomic indicators, parent market trends and growth drivers. To gain a better understanding of the market, primary and secondary research has been conducted. The data used in the report were subjected to a multi-step check to ensure both the authenticity and quality of the information provided. Bottom-up and top-down approaches are also used to ensure the credibility of appraisals and market segments.
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: It includes five chapters, details on the study's objectives, significant manufacturers covered, market segments, Androgen Replacement Therapy market segments, and years taken into account.
: The competition in the global Androgen Replacement Therapy market is assessed here in terms of price, turnover, revenues, and market share held by the organisation as well as market rate, competitive landscape, and most recent developments, transactions, growth, sales, and market positions of leading companies.
: On the basis of sales, primary products, gross profit margin, revenue, price, and growing production, the top players in the worldwide Androgen Replacement Therapy market are analysed.
: The report covers gross margin, sales, income, supply, market share, CAGR, and market size by region. Among the regions and countries thoroughly examined in this study are North America, Latin America, Europe, Asia Pacific, Middle East and Africa.
: It includes a comprehensive analysis of the contributions made by various end-user, application, and type segments to the Androgen Replacement Therapy Market.
: Production Side: The authors of this section of the report have concentrated on forecasting production and production value, forecasting key producers, and forecasting production and production value by type.
: The research study's conclusion is presented in this section of the report, which is its final subsection.
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Androgen Replacement Therapy Market to Grow Massively at a CAGR of 7.8% by 2030: Coherent Market Insights | - EIN News
Men with physically demanding jobs found to have higher sperm … – ESHRE
A study based on self-reported answers to a questionnaire cross-referred to semen samples and hormone measurements has found that physically demanding jobs and rotating or evening shift working may be associated with higher testicular function in men as seen by higher sperm concentrations and counts as well as higher serum testosterone and estradiol levels.
Male factor infertility has become a 21st century global problem, not only because of its link with reproductive health but also with a general risk of chronic disease such as diabetes and cancer. Concerns over declining sperm count and quality have been fuelled largely by the meta-analysis of Levine et al which, in an update last year, presented salutary new evidence of an acceleration in pace of this downswing.(1,2)
Various factors have been analysed to establish why sperm counts and concentration appear to have more than halved in 40 years. Numerous studies have focused on lifestyle, BMI, environment including endocrine-disrupting chemicals, and diet in the search for what might improve or impair sperm health. A recent RCT has even suggested that eating nuts might reduce sperm DNA fragmentation, a cause of reduced fertilisation rates and embryo quality.(3)
Now a new study suggests that mens occupations might be added to this long list of factors contributing to a decline in male reproductive health.(4) Observational data based on more than 300 participants show that sperm concentrations and serum testosterone levels among men who do physically demanding work are nearly double those of employees who never lift or move heavy objects. Certain work shift patterns also result in these positive associations. The findings are from the Environment and Reproductive Health (EARTH) study at Brigham and Womens Hospital and Harvard Medical School.
All participants in this latest EARTH study were also male partners of couples seeking fertility treatment, with a minority diagnosed with conditions such as cryptorchidism (5%) and varicocele (6%). The majority (87%) were of white ethnic background, with a median BMI of 27, and age ranging from 33 to 39 years. Enrolment took place between 2005 to 2019 with an aim of exploring the relationship between self-reported occupational factors and several markers of testicular function.
The men completed questionnaires about work shift patterns, how often they lifted or moved heavy objects, and physical level of exertion at work (eg, sitting, working in office etc); and were asked about lifestyle (eg, drug use, exposure to chemicals) and other factors such as diet. Semen samples were analysed following WHO guidelines, and multiple samples collected from most men. Of the 377 participants who completed the survey, 12% reported often lifting or moving heavy objects at work, 6% reported heavy physical exertion at work, and 9% reported evening or rotating shifts.
Overall, results showed most semen samples exceeded the WHO reference values. Men who reported often lifting/moving heavy objects at work had 46% higher sperm concentrations (P=0.01) and 44% higher total counts (P=0.01) than those who reported never lifting heavy objects. Results were similar for men on rotating shifts (defined as an alternating cycle of days/nights) compared to those on day shifts, and among men involved in heavy physical exertion compared to those engaged in light levels.
A subset of 145 participants had hormone measurements taken from blood samples. Of these workers, those involved in heavy/moderate levels of physical exertion in the workplace had higher circulating testosterone concentrations than those with lighter exertion, and men who often moved/lifted heavy objects had higher estradiol concentrations than those who never did. In addition, higher testosterone concentrations were observed among male workers on evening/rotating shifts: their levels were 24% greater than those of men on day shifts and estradiol concentrations 45% higher. No associations were observed for ejaculated volume, total motility, morphologically normal sperm, or serum FSH and LH concentrations.
The authors note that these results appear to conflict with earlier studies, which generally found work-related heavy exertion was linked to lower sperm concentration/total sperm count, with shift work not associated with semen quality. However, referring to a similar study reported in 2015, the authors note that participants here had generally higher median sperm concentrations/total sperm counts, and were younger but heavier than the men from the EARTH study.(5)
However, semen parameters among the EARTH study participants were comparable to those among young healthy men from the general US population, but the authors acknowledge a limiting factor in only sampling the male partners of couples having fertility treatment. It may not be possible to generalize our findings to men from the general population, they concede. However, they still propose that physically demanding jobs and rotating or evening shift occupations may be associated with higher testicular function in men as indicated by higher sperm concentrations and counts as well as higher serum testosterone and estradiol levels. But confirmation of these findings would only be derived from other non-fertility clinic study populations, and from subjects of different ethnic backgrounds.
1. Levine H, Jrgensen N, Anderson M-A, et al. Temporal trends in sperm count: a systematic review and meta-regression analysis. Hum Reprod Update 2017; 23: 646-659.doi.org/10.1093/humupd/dmx0222. Levine H, Jrgensen N, Anderson M-A, et al. Temporal trends in sperm count: a systematic review and meta-regression analysis of samples collected globally in the 20th and 21st centuries. Hum Reprod Update 2022;doi.org/10.1093/humupd/dmac0353. Salas-Huetos A, Moraleda R, Giardina S, et al. Effect of nut consumption on semen quality and functionality in healthy men consuming a Western-style diet: a randomized controlled trial. Am J Clin Nutr 2018; 108; 953-962. doi.org/10.1093/ajcn/nqy181. PMID: 304759674. Mnguez-Alarcn L, Williams PL, Souter I, el al. Occupational factors and markers of testicular function among men attending a fertility center; Hum Reprod 2023; https://doi.org/10.1093/humrep/dead0275. Eisenberg ML, Chen Z, Ye A, et al. Relationship between physical occupational exposures and health on semen quality: data from the Longitudinal Investigation of Fertility and the Environment (LIFE) Study. Fertil Steril 2015; 103; 1271-1277; doi.org/10.1016/j.fertnstert.2015.02.010
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Men with physically demanding jobs found to have higher sperm ... - ESHRE
Understanding the Hidden Connection Between Sleep and Sex – AskMen
What You Need to Know About the Relationship Between Sleep and Sex
Both sleep and sex are important for your health and well-being. But most people dont realize that one affects the other the quality of your sleep can determine the quality of your sex life, and vice-versa. For example, research shows that sleep disorders increase the risk of erectile dysfunction. And you know how having an orgasm can make you drowsy? Its due to the release of certain hormones.
Sleep and sex go hand in hand. Both are important for physical, mental, and emotional health and well-being, and problems in one often contribute to problems in the other, says Sarah Melancon, PhD, sociologist and clinical sexologist at Sex Toy Collective. Melancon previously worked in a sexual health clinic that included both sexual dysfunction and sleep programs. Frequently, sexual dysfunction patients also had sleep disturbances this is no coincidence.
RELATED:The Best Sleep Aids for aDeeper, Most Restful Sleep
Understanding the relationship between sleep and sex can help you improve your habits to optimize these two key areas of your lifestyle. Heres what you need to know.
Sleep is a restorative time that regulates the endocrine system, which produces our sex hormones, according to Melancon. For example, testosterone is an important sex hormone for men, fueling sex drive. Sleep affects the natural rhythm of your testosterone levels and can thus affect your sexual health and libido. Research has shown that sleep loss reduces testosterone levels in males. Testosterone works partly in alignment with our circadian rhythm, peaking in the morning and falling throughout the day. In particular, REM sleep is important for testosterone synthesis and appears associated with nocturnal erections, adds Melancon.
So, if you suffer from insomnia or dont get enough quality sleep, it can have an impact on your ability to crave sex and perform in the bedroom partly because of the link between sleep and testosterone, but also because of other factors. For instance, one study found a significant connection between insomnia and sexual dysfunction. According to the researchers behind the study, stress may be to blame, as being stressed may not only cause sleep disturbances, but can also negatively affect sexual function.
Sleep apnea is a potential disruptor as well: several studies have found a link between sleep apnea and erectile dysfunction. The takeaway? Sleep hygiene matters more than you think when it comes to your sex life.
Now that you understand how sleep can affect sex, lets consider how sex can affect sleep. The most important thing that you need to know is that an active sex life can improve the quality of your sleep.
If you have found yourself drowsy and uncontrollably sleepy after sex, it is normal. When a man reaches ejaculation, various chemicals are released from the brain, including prolactin, vasopressin and oxytocin. Prolactin is a hormone present in sleep and is also linked to sexual satisfaction in men. When you have sex, the orgasms from intercourse releases prolactin four times more than prolactin released during masturbation, according to Nicole Eichelberger, a BSM-certified sleep experts specializing in insomnia, apnea, and circadian rhythm disorders and a consultant at Mattressive. According to her, during sex, your levels of cortisol the stress hormone also drop. As she puts it, sex can positively affect a man's life, as a man with an active sex life sleeps better.
Theres an interesting other side of the coin sexual frustration, which can increase stress and interfere with a good night of sleep. Sexual frustration may be conceptualized as sexual tension plus a lack of satisfying release, accompanied by feelings of stress, anxiety, or even anger all of which interfere with sleep, says Melancon.
To recap the information above, sleep disturbances can cause problems in the bedroom, yet having sex can improve your sleep. Its a bit of a vicious cycle, but you can take steps to turn it into a virtuous one and improve both your sleep and sex life.
The first order of business is aiming to get a full nights sleep every night longer sleep is associated with healthy testosterone levels, according to Melancon, who recommends living in accordance with your natural circadian rhythm to help you get there. How? Go to bed early and awake around sunrise. Get early-morning and midday sunlight on your skin and in your eyes (without glasses). Use blue light-blocking glasses in the evening and red glasses an hour before bed to stimulate the release of melatonin, which helps you feel sleepy. TrueDark is a good brand, says Melancon.
Exercise is also crucial, as it improves both sleep and sexual function. Youll also want to take care of your mental wellbeing. Use mindfulness, yoga, tai chi, qigong, or related practices to relax and de-stress. Mindfulness has been found to improve erectile dysfunction, adds Melancon. Finally, as Philip Lindeman, MD, PhD, a physician and sleep specialist at GhostBed suggests, avoid excessive alcohol: It's not going to help sex or sleep.
If you adopt all the lifestyle changes above and still struggle with sleep and sex, talk to your doctor there may be underlying medical issues to address, such as getting treatment for sleep apnea. Great sex and sleep await.
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Understanding the Hidden Connection Between Sleep and Sex - AskMen
Trans kids say they have target on their back with GOP initiative – The Atlanta Journal Constitution
Republican lawmakers in Georgia are trying to change the law to stop transgender minors like Michael from receiving hormone replacement therapy or having surgery to help them physically align with their gender identity.
From birth, Michael was raised as a girl. But Michael said he knew for years that he was a boy. The pain of living his life in a body that didnt match his gender identity led him to self-harm and suicidal thoughts. He credits hormone treatment, in his case testosterone, with giving him a path to bringing his body and his identity into alignment.
Now, cases like Michaels have exploded into the political consciousness as some conservatives voice concern that such treatments are hasty. Legislatures in red states across the nation are proposing bills to intervene. In Georgia, versions of the bill have passed both chambers. It would apply to anyone under 18 years of age.
Credit: arvin.temkar@ajc.com
Credit: arvin.temkar@ajc.com
The House on Thursday passed Senate Bill 140 largely on a party-line vote, with Republicans supporting the measure. Such party-line votes on the issue are the norm in the Republican-majority General Assembly. Since the bill was amended in the House, it will now go back to the Senate for its consideration.
Its not the first time transgender children felt like they were political targets in Georgia.
Last year, lawmakers passed a bill that allows any athletic association to ban transgender girls from competing on girls teams. A month later, the Georgia High School Association voted to require athletes to compete based on their biological sex.
This years bill would ban health care professionals from giving hormones such as estrogen or testosterone to transgender minors. Doctors also would not be allowed to perform surgeries on children seeking to align with their gender identity.
Treatment for transgender adolescents is a two-step process, first pausing hormones and puberty, and then giving new hormones to advance puberty in the target sex. If the bill becomes law, the second step would be banned for those under 18.
Medical professionals would still be allowed to prescribe a hormone treatment that aims to delay puberty or stop it from progressing under the proposal. Children who dont identify with their biological sex at a young age are often prescribed the puberty blockers.
Scientists who deal with such patients say a new, yearslong delay between pausing puberty and beginning hormone replacement therapy could lead to both physical and psychological issues.
The bill would also allow for minors to continue to receive hormone treatments if they began before July 1, when the bill, if signed into law, would take effect, so minors in Michaels situation wouldnt be affected.
Credit: arvin.temkar@ajc.com
Credit: arvin.temkar@ajc.com
SB 140s sponsor, state Sen. Carden Summers, a Cordele Republican, says the legislation aims to stop parents from allowing their children to make permanent decisions about their gender identity before they are legal adults.
Its also been proven that children who have gender dysphoria issues sort of outgrow them as they mature. ... They should get a little bit more mature before they make a decision that is 100% irreversible, he told the House Public Health Committee on Tuesday. After (transgender children turn) 18 years old, whatever they decide to do is their business. This bill is simply to pause.
An AJC reporter contacted organizations more than a week ago that support the legislation in an attempt to speak with Georgians who received transgender treatment and regretted transitioning. The person whose information was provided did not respond to a request for comment.
Opponents of the legislation say bills such as SB 140, which are advancing across the country in Republican-controlled legislatures, are targeting a small, already vulnerable population. According to a 2022 study by the law school at the University of California, Los Angeles, about 1.2% of Georgians between the ages of 13 and 17 identify as transgender, or about 8,500 minors.
Studies have found that transgender youth, and adults, consider suicide at a rate exponentially higher than those who are not transgender.
Michael first told his mother that he was transgender when he was about 11 years old, but the family didnt immediately address it. Thats when Michael said he fell into a depression and began cutting his arms as a way to deal with what he was feeling. Cutting, or self-injury, is a nonsuicidal, yet harmful way to cope with emotional pain, sadness, anger and stress. Michael said he eventually considered suicide.
I didnt understand at the time, but seeing Michael in so much pain made it impossible not to address, his mother said. I needed Michael to be happy, and I was going to do whatever that took.
A study published in 2020 in the Journal of Interpersonal Violence, a peer-reviewed publication that studies victims and perpetrators, found that 56% of transgender youth between ages 14 and 18 who were surveyed said they had tried to take their lives within the previous six months.
According to a 2019 U.S. Centers for Disease Control and Prevention study, 9% of high school students reported attempting suicide in the previous 12 months.
Credit: arvin.temkar@ajc.com
Credit: arvin.temkar@ajc.com
The British journal The Lancet reported a risk of suicide in one U.S. study in 36% of patients of all ages with gender dysphoria the distress that comes from feeling youre one gender when you physically look like another. In contrast, risk of suicide was found in only 5% of the group without gender dysphoria.
Major scientific organizations such as the American Medical Association, the American Academy of Pediatrics and the World Health Organization say that medical and surgical care to transition genders is appropriate when properly administered.
Some dissenters have formed alternate groups, disagreeing with the organizations and calling for a halt to such treatments.
Erica Anderson, a California-based clinical psychologist and former board member of the World Professional Association for Transgender Health, told a reporter for the website the BMJ that she believes some kids are allowed to transition too fast.
We dont have lab tests that reveal if someone is trans nor not, Anderson told the BMJ. We have growing numbers of self-reported transitions that were very rapid in my opinion, too rapid getting on hormones right away, getting gender affirming surgery, and then shortly thereafter regretting it all.
Health care leaders in Finland and Sweden have slowed the administration of gender-affirming care in adolescents, recommending it only on a case-by-case basis.
In issuing the new Swedish guidelines, that countrys National Board of Health and Welfare cited the lack of new research and what it called the new knowledge that some young transition patients have regretted their transition and reversed their transition.
It also said that the number of young patients seeking to transition had significantly increased in recent years, especially among those seeking to transition from female to male, and that it wanted to better understand why.
Credit: Natrice Miller/AJC
Credit: Natrice Miller/AJC
To minimize the risk that a young person with gender incongruence later will regret a gender-affirming treatment, the Swedish guidelines were changed, it said. It added, Questions on how to ensure that all young people suffering from gender dysphoria be taken seriously and confirmed in their gender identity, well received and offered adequate care are becoming increasingly relevant, and will need to be answered.
Scientists say that some patients who transition end up stopping, and some end up reversing their transition. But they say the numbers are tiny compared with the numbers who transition.
However, many of those who specialize in transgender care say that careful psychological assessment is important.
Dr. Dane Whicker of Duke Universitys School of Medicine, a clinical psychologist who works with transgender patients, said hes had two or three kids in his decade-plus experience who didnt go through transitioning.
A key point is the concept of regret.
Stopping or reversing a transition doesnt mean the patient regretted the transition, said Dr. Angela Kade Goepferd, a pediatrician and medical director of gender health at the Childrens Minnesota hospital system. Instead, she said, almost all of those who stop often adults do so because theyre getting backlash from their communities and families.
Theyre experiencing too much stigma, too much discrimination, and they just cant do it, Goepferd said. Its not that they want to stop, but they feel like thats the choice they have to make.
Dr. Izzy Lowell, who runs the Decatur-based gender transition practice Queer Med, said her clinic has about 4,000 active clients from across the South, and about 20% of them are under 18.
She has a handful of patients who are as young as 6 or 7 who only come in to her practice once a year and receive no medical treatment. The bulk of her patients that are under 18 are in their teens and usually have to have already started puberty before being treated with puberty blockers or other hormones. She does not do surgical treatment on minors, nor does she know anyone who does in Georgia.
Lowell said people who seek out her practice want medical treatment, though she partners with mental health providers for patients who want to undergo therapy.
In the best cases, the family has known theyre trans their whole life, they come in and, as soon as we can, we get them on treatments, everything goes smoothly and they never have to experience the wrong puberty and go through that terrible dysphoria, Lowell said. The worst cases, patients come to me after a suicide attempt and the family decides that theyll try anything not to have their child kill themselves. And thats far more common than it should be.
Credit: arvin.temkar@ajc.com
Credit: arvin.temkar@ajc.com
Families with transgender children who spoke with the AJC say that while it may have taken children a while before putting the feeling that they were transgender or nonbinary into words, it was always evident. Someone who is nonbinary doesnt identify as strictly male or female. Dare, a 16-year-old from Dacula who uses they as their pronoun, said they were about 10 when they started to think they may be nonbinary.
Ive always been gender neutral my whole life, Dare said. My mom talks about how, when I was really little, I would pick toys from the boys aisle and the girls aisle.
Dare and their sibling, a 13-year-old transgender boy named Jay, told their parents about their gender identities about the same time in 2020. Neither has been able to secure an appointment to get a diagnosis of gender dysphoria and begin medical treatment, so their transition has been social meaning changing their names and dressing in a way that more aligns with their gender identity.
Being nongender conforming isnt a decision thats made on a whim, Jay said. Theyve most likely known for a long time before they decided to tell anyone.
Credit: arvin.temkar@ajc.com
Credit: arvin.temkar@ajc.com
Jen Slipakoff, a Kennesaw resident, said her daughter first started talking about being transgender when she was 5. Up until then she had been raised as a boy. Shes 15 now.
We already knew exactly what was happening before she ever said anything, Slipakoff said. She has an older brother, so our house was full of traditional boys toys. And our daughter would play with those toys in a very different way than our son was. She would take her little soldiers shopping instead of putting them on the battlefield. She was always drawn to what we would consider traditional girls toys and traditional female clothing.
When she turned 5, she asked her mother to change her name.
She became more and more insistent, Slipakoff said. Thats when we realized like OK, this is something that we need to address.
During a Senate hearing last month, Slipakoff told lawmakers she was concerned that her teenage transgender daughter would be bullied by her classmates when she came out as trans.
Im happy to report, she has never been bullied by her classmates, Slipakoff said. Thats not to say she doesnt have bullies. Here in this room right now, they sponsored this bill and theyre the ones that are going to vote for it. ... She doesnt want and she doesnt need your protection. She wants you to leave her alone.
Democratic lawmakers and other opponents of SB 140 have also questioned how the same group of lawmakers could push legislation last year that allowed parents to opt their children out of school policies for things such as vaccines, masks and lessons and now say that parents shouldnt be able to make health decisions for their children.
During a House panel debating the legislation on Tuesday, state Rep. Shelly Hutchinson, a Snellville Democrat, read a series of arguments Republican lawmakers made in the media during those debates. Among them were comments such as parents have the right to make decisions about their childrens health care without interference from government.
At what point did Georgia shift from giving parents rights to taking away their rights for whatever medical treatment they deem appropriate with their doctors? she asked Summers.
Im just doing the bill to protect children, Summers said. Thats it, pure and simple.
Opponents of the bill say it would harm more children than it would help.
Michael, the 17-year-old Duluth resident, said if SB 140 was the law at the beginning of his transgender journey and banned him from receiving testosterone, he doesnt think he would still be living.
I most likely, honestly, would not be alive, he said. Thats what Im saying. Thats how much it affects me. Thats how much its changed my life. And I just couldnt imagine it because I know where I was, and I know I wouldnt be here without it.
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Trans kids say they have target on their back with GOP initiative - The Atlanta Journal Constitution
5 Athletes Receive 3-Year USADA Suspensions After No-Gi Worlds – FloGrappling
USADA announced today that five athletes have accepted three-year sanctions for their respective anti-doping rules violations, all of which occurred as a result of testing and intelligence from the International Brazilian Jiu-Jitsu Federation (IBJJF) World No-Gi Championship event in December 2022.
Igor Nascimento da Costa Feliz, 24, of Port San Lucie, Fla., tested positive for exogenous testosterone and its metabolites as the result of an in-competition urine sample collected on December 11, 2022, at the World No-Gi Championships. He accepted a three-year period of ineligibility that began on January 24, 2023, the date he was provisionally suspended from competition.
Jonnatas Gracie Araujo da Silva, 25, of San Diego, Calif., tested positive for 19-norandrosterone (19-NA), a metabolite of nandrolone and other prohibited 19-norsteroids, and exogenous testosterone and its metabolites as the result of an in-competition urine sample collected on December 11, 2022, at the World No-Gi Championships. He accepted a three-year period of ineligibility that began on January 25, 2023, the date he was provisionally suspended from competition.
Roberto de Abreu Filho, 42, of Miami, Fla., tested positive for exogenous testosterone and its metabolites as the result of an out-of-competition urine sample collected on December 20, 2022. He accepted a three-year period of ineligibility that began on January 27, 2023, the date he was provisionally suspended from competition.
Jos Henrique Cardoso, 29, of Santa Catarina, Brazil, tested positive for 19-NA, 2a-methyl-5a-androstan-3a-ol-17-one (a drostanolone metabolite), epitrenbolone (a trenbolone metabolite), methasterone, and exogenous testosterone and its metabolites as the result of an out-of-competition urine sample collected on January 24, 2023. He accepted a three-year period of ineligibility that began on February 1, 2023, the date he was provisionally suspended from competition.
Vagner S. Rocha, 40, of Davie, Fla., refused to submit to sample collection after being notified by a USADA doping control officer during an out-of-competition test on December 23, 2022. He accepted a three-year period of ineligibility that began on January 11, 2023, the date he was provisionally suspended from competition.
Under Article 10.8.1 of the Code, an athlete who faces an anti-doping rule violation that carries a period of ineligibility of four or more years may receive a one-year sanction reduction if the athlete admits the violation and accepts the asserted sanction within 20 days of notification of the alleged anti-doping rule violation charge. Per the rule, all five athletes qualified for a one-year reduction to the otherwise applicable four-year period of ineligibility.
In addition, all the athletes have been disqualified from competitive results achieved in competitions sanctioned by the IBJJF, or any Code signatory, on and subsequent to December 11, 2022, the date the 2022 IBJJF World No-Gi Championships started.
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5 reasons for low sex drive in men these days and how to treat it – Indiatimes.com
TIMESOFINDIA.COM | Last updated on - Mar 11, 2023, 00:00 IST
Among every 5 men 1 faces the problem of low libido due to various reasons like stress or hormonal imbalances that make them want to avoid any kind of sexual activity. Yet, sometimes a loss of sex desire is a symptom of a deeper issue. Men's decrease of sex desire can frequently be attributed to depression, stress, drunkenness, illicit drug usage, and weariness.
Here are several reasons why men may experience low sex drive:
High levels of stress can affect testosterone levels and reduce sex drive. If a person is distracted by a certain situation or goes through severe mental pressure, then his sexual drive decreases.
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Dr. Caranj S.V., M.B.B.S., M.S. (General Surgery), M.Ch. (Urology), Medical expert with Kindly Health says, Issues such as low testosterone levels, can lead to decreased sex drive. Men who have hypogonadism are determined to struggle with the problem of low testosterone levels estimated below 300 ng/dl. Such men face a lack of urge for any sexual activity.
Some medications can have side effects that reduce sex drive, such as antidepressants and blood pressure medications. Men taking radiation treatments or chemotherapy for cancer suffer from decreased sex drive along with those who take anabolic steroids like sportsmen.
Poor diet, lack of exercise, smoking, consumption of excessive alcohol, and drug use can all contribute to low sex drive. Also, if proper sleep and rest are not taken then that also creates problems and causes low sex drive.
Problems with a partner, such as communication issues or unresolved conflicts, can reduce sexual desire.
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Addressing stress: Finding ways to manage stress, such as through exercise, meditation, or therapy, can help improve sex drive.
Adopting a healthier lifestyle: Cessation of smoking, eating a balanced diet, exercising regularly, and reducing alcohol and drug use can all help improve sex drive.
Treating hormonal imbalances: According to Dr. Caranj, If low testosterone levels are the cause, hormone replacement therapy may be necessary.
Addressing relationship issues: Working with a partner to address communication issues and resolve conflicts can help improve sexual desire.
Switching medications: If medication side effects are the cause, switching to a different medication may be necessary.
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Kai Greene Discusses Steroids vs. Natural Competition: I Believe In Unenhanced Athletic Performance&… – Generation Iron Fitness Network
Despite not being part of competition anymore, Kai Greenecontinues to be a strong fitness mind who crushes different workouts on a daily basis. In a recent interview, Greene was asked about his opinion on steroids and testosterone replacement therapy while also sharing his current diet routine.
Greene has not been on stage since 2016. He was an extremely popular competitor in Mens Open over the course of two decades. He had a chance to compete against some of the best in the world including Jay Cutler and Dexter Jackson.
Greene became most known for his battles with Phil Heath on the Olympia stage. No matter what sport it is, rivalries are what make it great. Greene and Heath have one of the all-time rivalries in bodybuilding and fans were entertained for years watching the two go at it.
Now, Greene continues to train himself in the gym but is also used as a coach for others. Kai Green is featured in the Generation Iron documentaryKai,which takes a comprehensive and official look at the life and career of the bodybuilding legend. The film can be watched here.
Adams AppleYouTube page caught up with Kai Greene for a candid interview, where he was able to discuss steroids and his current diet plan. Greene shared that his diet varies between 2,500 and 6,000 calories per day and that it depends on his target.
Its particular work that has to be done and the numbers can vary. I can do anywhere between 6,000 calories in a day and sometimes come down to maybe 2,500, depending on where we are in the process of preparation.
When it comes to steroids and PEDs, there are many using TRT as a replacement. According to Greene, this is still a steroid.
If youre getting it for PED, performance-enhancing or youre buyingtestosterone for natural male hormone replacement therapy.
With that said, it is a steroid to my knowledge. But there are plenty of supplements designed to boost your own natural testosterone production.
During his career, Kai Greene admitted to competing naturally for over 15 years because he believes in natural performance.
I believe in unenhanced athletic performance. I believe theres a lot of children getting involved in the sport newly.
Its important to be able to find out what you can do and be willing to go as far as you can and beyond that, from an unenhanced perspective, being natural. I competed for more than 15 years as an unenhanced natural athlete, very, very, very proud of that.
Kai Greene might not be competing anymore but he remains an influential voice in bodybuilding because of where he came from and the success he had on stage. Over the course of his career, he was able to get the most out of his physique and did it naturally.
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Kai Greene Discusses Steroids vs. Natural Competition: I Believe In Unenhanced Athletic Performance&... - Generation Iron Fitness Network
10 Causes of Erectile Dysfunction in 20s – DISCOVER Magazine
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Erectile dysfunction (ED) is a sexual disorder that affects millions of men worldwide. It is often associated with aging, but it can occur in younger men as well. While ED can be an embarrassing and frustrating condition to deal with, it is important to understand that it is often caused by underlying medical or psychological factors that can be treated.
Today you can explore more information about the 10 causes of erectile dysfunction in 20s by continuing to read below. By understanding the potential causes of ED, young men can take steps to address and overcome this condition, improving their sexual health and overall well-being.
Erectile dysfunction (ED) can be caused by a variety of physical and psychological factors. Here are ten possible causes of ED in men in their 20s:
Anxiety and stress can cause ED (erectile dysfunction) in several ways. Firstly, when a person is anxious or stressed, their body releases stress hormones, such as adrenaline and cortisol, which can cause a narrowing of the blood vessels. This narrowing reduces blood flow to the penis, making it difficult to achieve or maintain an erection.
Performance anxiety is a type of anxiety that occurs in situations where a person feels pressure to perform or achieve a specific goal. In the context of sexuality, performance anxiety refers to the fear or worry about sexual performance, which can lead to difficulty achieving or maintaining an erection, premature ejaculation, or difficulty reaching orgasm.
Performance anxiety can be caused by a variety of factors, including past negative sexual experiences, relationship issues, or a fear of being judged or rejected by a sexual partner. This type of anxiety can also be exacerbated by other factors, such as stress, fatigue, or alcohol and drug use.
You can find a variety of relationship issues that cause erectile dysfunction in 20s, such as lack of emotional connection, communication issues, infidelity, breakdown of trust, and sexual incompatibly. These are just a few of the many relationship issues that could cause a man in his 20s to suffer from ED symptoms.
Pornography addiction can cause ED in several ways. First, excessive pornography use can desensitize the brain's reward center, leading to a decrease in dopamine receptors, which are necessary for sexual arousal and satisfaction. This can result in a decrease in sexual desire and the inability to achieve or maintain an erection.
Second, pornography addiction can cause anxiety and depression, which are known to contribute to ED. When individuals become dependent on pornography for sexual gratification, they may experience guilt, shame, and low self-esteem, which can lead to anxiety and depression.
Lastly, pornography addiction can lead to physical changes in the brain that affect sexual function. Studies have shown that prolonged exposure to pornography can cause changes in brain structure and function, leading to difficulties with sexual arousal and function.
Substance abuse can have a negative impact on sexual function and lead to erectile dysfunction (ED). Substance abuse can damage the nerves and blood vessels needed for a healthy erection, reducing blood flow to the penis and impairing nerve function. Additionally, drugs and alcohol can cause hormonal imbalances and decrease testosterone levels, which can further contribute to ED.
Some medications can cause ED as a side effect by affecting the blood flow or nerve signals in the body. In some cases, medication-induced ED may be temporary and can be reversed by adjusting the dosage or switching to a different medication. However, it is important to consult with a healthcare professional before making any changes to your medication regimen.
Obesity can cause ED in several ways. First, it can lead to the development of cardiovascular disease and diabetes, which are two conditions that can damage blood vessels and nerves essential for erectile function.
Second, obesity can lower testosterone levels, which can lead to a decrease in sexual desire and difficulties achieving or maintaining an erection. Another reason that obesity can cause erectile dysfunction in 20s is that it can contribute to psychological factors such as low self-esteem, depression, and anxiety, which can also affect sexual function.
Diabetes can cause erectile dysfunction (ED) in men of all ages, including those in their 20s. The condition affects blood vessels and nerves throughout the body, including those in the penis that are responsible for creating and sustaining erections.
High levels of blood sugar can cause damage to blood vessels and nerves, leading to reduced blood flow to the penis and reduced sensitivity of nerves in the area, making it difficult to achieve or maintain an erection.
Testosterone is a hormone that plays a crucial role in male sexual function. Low levels of testosterone can cause a range of sexual problems, including erectile dysfunction (ED). Testosterone helps to stimulate the production of nitric oxide, a chemical that helps to relax the muscles in the penis and increase blood flow. This increased blood flow is necessary for an erection to occur.
When testosterone levels are low, the production of nitric oxide is reduced, which can lead to difficulty in achieving and maintaining an erection. Low testosterone levels can also cause a decrease in sex drive, which can contribute to ED.
Peyronie's disease is a condition in which scar tissue forms inside the penis, causing it to curve or bend. This can make erections painful or difficult to achieve, leading to erectile dysfunction (ED).
The scar tissue can prevent the smooth expansion and contraction of the erectile tissue, reducing blood flow to the penis during arousal and making it difficult to achieve and maintain an erection. In addition to physical discomfort, Peyronie's disease can also cause anxiety, stress, and emotional distress, which can further exacerbate ED.
There are several ways to potentially reverse ED symptoms, depending on the underlying cause. Here are some possible options:
Making changes to your lifestyle can help improve ED symptoms. This can include regular exercise, maintaining a healthy diet, quitting smoking, reducing alcohol consumption, and managing stress.
Medications such as phosphodiesterase type 5 (PDE5) inhibitors, such as sildenafil (Viagra), tadalafil (Cialis), and vardenafil (Levitra), are often prescribed to treat ED. These medications increase blood flow to the penis, helping to achieve and maintain an erection. However, they do require a prescription from a healthcare provider.
For some men, psychological factors such as anxiety, depression, or relationship issues can contribute to ED. Counseling or therapy may help address these underlying issues and improve sexual function. This is a great way to help men who are experiencing anxiety, stress, or relationship issues.
Not to mention, counseling for those with additions that are causing an issue with erectile dysfunction in 20s could prove to be an easier option to reverse the ED symptoms in 20s.
It's important to talk to a healthcare provider about the best treatment options for you, as they can help determine the underlying cause of your ED and recommend the most effective course of action. Now that you know more about the 10 causes of erectile dysfunction in 20s, and how you could potentially reverse those symptoms, here are more details about the most recommended over the counter options for ED symptoms today:
Image courtesy Elm and Rye
Elm and Rye's Libido Gummies are a one-of-a-kind dietary supplement that promotes healthy sexual function and enhances libido for both men and women. Comprised of natural ingredients such as maca root, horny goat weed, and ginseng, these gummies can increase sexual desire, bolster endurance, and foster overall sexual wellness.
With their natural composition, these gummies offer a safe and effective alternative to prescription medications. Simply consume two gummies per day to help support healthy sexual function and elevate libido.
Elm and Rye ensures the quality and safety of their Libido Gummies by crafting them with premium ingredients in a GMP-certified facility. These gummies also contain no artificial colors, flavors, or preservatives, making them a healthy and natural addition to your daily regimen.
Image courtesy Penguin
Penguin Male Libido Capsules are a thoughtfully crafted dietary supplement designed to foster healthy sexual function and augment libido in men. These capsules are made with a powerful blend of natural ingredients, including tongkat ali, muira puama, l-arginine, ginseng, and more, that work in tandem to enhance sexual performance in various areas of the body.
Each serving of Penguin Male Libido Capsules contains a potent dose of 8mg of Zinc, 140mg of Tongkat Ali, 134mg of Muira Puama, 100mg of Siberian Ginseng, 50mg of Maca, 50mg of Nettle, 10mg of Saw Palmetto, and 3mg of Yohimbe. These ingredients were meticulously selected for their ability to bolster sexual function, increase endurance and stamina, and elevate libido.
Tongkat Ali, a natural herb, is known to heighten testosterone levels, thereby enhancing sexual desire and performance. Meanwhile, Muira Puama, an aphrodisiac used for centuries, is renowned for its ability to improve sexual function and support overall sexual health.
Siberian Ginseng and Maca, two natural adaptogens, can elevate energy levels and reduce stress, leading to a positive impact on sexual function. Additionally, Nettle and Saw Palmetto are included in the formula for their ability to support prostate health, which is crucial for overall sexual function.
Image courtesy Everest
Everest's Full Spectrum CBD Gummies for ED offer a superb natural remedy for individuals seeking a safe and effective solution to improve their sexual health. These gummies are infused with high-quality CBD and THC extracted from naturally grown hemp, ensuring maximum efficacy and potency.
Each gummy is packed with a delicious Blue Raspberry flavor and is vegan and Non-GMO. The hemp utilized in these gummies is grown in the USA, adhering to the highest quality standards.
With 5mg of THC per serving, in addition to other cannabinoids, terpenes, and flavonoids, these Full Spectrum CBD gummies provide the entourage effect, augmenting the overall benefits of the CBD and THC. The full spectrum of cannabinoids and terpenes present in these gummies enhances the overall efficacy, making them a superb choice for improving sexual health.
Image courtesy Colorado Botanicals
Colorado Botanicals CBD Gummies for ED provide an exceptional natural remedy for individuals seeking to improve their sexual health. These gummies are infused with high-quality CBD extracted from organic, non-GMO hemp grown in the USA, ensuring premium quality.
With a delicious mixed berry flavor, these gummies offer a convenient and enjoyable way to incorporate CBD into your daily routine. The CBD utilized in these gummies is a broad-spectrum extract, containing a comprehensive range of cannabinoids, terpenes, and flavonoids, but is entirely THC-free, making them an ideal choice for individuals who prefer to avoid THC.
Image courtesy Charlottes Web
For individuals seeking a natural remedy to improve their sexual health, Charlotte's Web CBD Gummies for ED offer an excellent solution. These gummies are infused with high-quality CBD extracted from organic, non-GMO hemp grown in the USA, ensuring superior quality.
With a delicious natural fruit flavor, these gummies provide a convenient and enjoyable way to incorporate CBD into your daily routine. The CBD utilized in these gummies is a full-spectrum extract, containing a comprehensive range of cannabinoids, terpenes, and flavonoids, including a small amount of THC.
Image courtesy Verma Farms
Verma Farms CBD Gummies offer a delicious and convenient way to incorporate the benefits of CBD into your daily routine. Made from high-quality, non-GMO hemp grown in the USA, these gummies are infused with full-spectrum CBD extract, ensuring you receive the full range of cannabinoids, terpenes, and flavonoids.
These gummies come in a variety of flavor options, each bursting with delicious taste, making them a treat that you will look forward to taking every day.
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10 Causes of Erectile Dysfunction in 20s - DISCOVER Magazine
From Acne To Wrinkles: How Hormones Affect Skin – Women’s Health
Collectively, hormones act as your bodys conductora group of behind-the- scenes powerhouses that influence nearly everything from your energy levels to your appetite. Skin, too, is subject to the whims of these potent chemical messengers (think of that sudden breakout that serves as a reminder to stock up on tampons). Generally, this tight relationship is a good thing: Hormones stimulate oil glands and follicles to lubricate skin and grow hair, says Jessie Cheung, MD, a dermatologist in Chicago. Theyre also necessary to maintain skin health.
But things can go a little haywire because your skin is packed with receptors that react to changes, triggering things like acne, wrinkles, and so forth. Puberty is probably the first time you noticed this (hello, zits, nice to meet you), but the ups and downs keep coming, even when youre fully settled into adulthood. The encouraging news? A few tweaks to your routine help you stay glowy for good.
In the first trimester, youre likely dealing with a spike in progesterone, which preps your uterus for a baby. Progesterone can increase oil production and bouts of acne, says Melissa K. Levin, MD, a dermatologist in New York City. The response can be unpredictable, though, which is why you could be breakout central while your pregnant friend is positively radiant. Estrogen also rises during pregnancy, and that, combined with progesterone, can contribute to the formation of melasma, which appears as dark brown spots or patches.
How to handle it: Treatment options are limited since many classic acne-fighting ingredients, like retinoids, salicylic acid, and benzoyl peroxide, are off-limits. Youre not totally out of solutions, though. If youre dealing with stubborn acne, Dr. Levin recommends azelaic acid, which helps with both breakouts and pigment. Worth a shot as well: lactic acid and sulfur, which help keep pores clear. You can also ask your doctor about topical antibiotics, like clindamycin, which is pregnancy-safe. Melasma is another convo since its both chronic and multifactorial. Long-term management may include Rx options like hydroquinone and oral meds (youll have to wait until youre done breast- feeding). Sun is another major factor in melasma, so load up on SPF.
External stressors (think divorce, moving, living through a worldwide pandemic) trigger a domino effect within the body that contributes to a shift in hormones, says Dr. Levin. Increased chronic stress can up androgens like testosterone, which stimulates production of pore-clogging oil, she says.
How to handle it: Retinoids, including over-the-counter retinol and prescription-strength retinoids, are the gold standard for offsetting acne. They help expedite skin-cell turnover to minimize and prevent clogging buildup, says Dr. Levin. Certain retinoids, like adapalene, can also be anti-inflammatory and help treat post-acne marks. She recommends pairing them with antibacterial agents such as benzoyl peroxide (which kills the acne-causing bacteria) or gentle exfoliants like salicylic acid, to keep dead skin cells from sticking together and potentially forming clogs. Oral medications are also an option. Spironolactone is a popular one; it regulates testosterone sensitivity on the skin by decreasing the amount of a specific type of testosterone, Dr. Levin says. And, of course, good stress-handling habits, like getting enough sleep and exercising regularly, will also help.
This is the transitional time leading up to meno (which is when your estrogen and progesterone officially call it a day) and hormones are fluctuating wildly. That new imbalance can cause dryness, says Dr. Levin. And since estrogen drives the formation of structural proteins like collagen and elastin, dips lead to losses in both, often making for more fine lines. With estrogen AWOL, testosterone will dominate, says WH advisor Mona Gohara, MD, an associate clinical professor of dermatology at Yale University. That may bring on breakouts and rosacea.
How to handle it: Since skin might be at its driest ever, everything you do should be rooted in hydration, says Dr. Gohara, who recommends products with humectant ingredients such as glycerin and hyaluronic acid. To address lines, try a collagen-stimulating retinoid. Topical ingredients that activate estrogen receptors in skin, like methylestradiolpropanoate, or MEP, have been shown in studies to improve dryness, dullness, and laxity.
Three different serumsfor purifying, soothing, and energizingare meant to be used consecutively to help you glide through your monthly cycle.
When pregnancy pimples strike, this serum, with azaleic acid and bakuchiol (a plant-based retinol alternative), will keep you in the clear.
Dryness can be tough during perimenopause. This rich cream is packed with heavy-hitting hydrators like hyaluronic acid and lipids.
Collagen-building peptides are paired with a blend of powerful protective antioxidants (green tea, vitamin E) to firm later-in-life skin.
After menopause, youre no longer dealing with the estrogen and progesterone ups and downs, so youll lose a good amount of collagen, says Dr. Levin. That can cause deeper wrinkles and lax skin. The upside: The chance of breakouts goes way downso if youve dealt with adult acne, this might be your clear, calm moment.
How to handle it: Look for peptides in your skin-care products (scan the ingredient label). Theyre the building blocks of certain proteins that drive an increase in collagen, says Dr. Levin. (In other words, they give your skin the materials to create more of it.) She also recommends antioxidants, which help repair and defend against damage, as well as growth factors, proteins produced by our cells that regulate cell growth, maintain tissue, and contribute to the repair and production of collagen. This might also be a good time to consider in-office treatments such as lasers, radiofrequency, and microneedling. These procedures create controlled, microscopic injuries to skin to trigger new collagen productionand may create a more pronounced effect than products alone, says Dr. Levin.
Deanna Pai is a freelance beauty writer and editor currently based in New York. She has more than 10 years of experience writing about beauty and wellness.
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From Acne To Wrinkles: How Hormones Affect Skin - Women's Health