Search Weight Loss Topics:

Page 67«..1020..66676869..8090..»

Home » Testosterone » Page 67

From the tip of a poofy tail, to the tip of a dog-like wet nose, ring-tailed lemurs can communicate in silence.

The lemurs an endangered primate native to Madagascar are known for a particularly acute sense of smell compared to other primates. Scent glands on their genitals, shoulders, and wrists let them communicate specific messages for fighting, climbing the social ladder, and flirting or stink-flirting. In a new study published today in the journal Current Biology, chemists from the University of Tokyo have pinpointed the fruity, floral chemicals key to lemur love connections. Some may rush to declare this as the first discovery of primate pheromones, but experts are reluctant to agree.

During breeding season, a male ring-tailed lemur will slip his long tail in and out of his arms. As the tail slides through, it rubs against scent glands in his wrist. The male then wafts his tail toward a female, dispersing a diverse bouquet of smelly chemicals.

Male ring-tailed lemur showing antebrachial (wrist) glands

Japan Monkey Centre (CC BY)

Previous research has suggested that female lemurs are more receptive to males flirting this way than those not spreading scents. Its not yet clear whether stink-flirting actually leads to more mating. But given the ring-tailed lemurs reliance on smell, zoologists suggest that the animal may indeed communicate with sex pheromones.

Efforts to unravel the chemical secrets behind lemurs smell-based communication are nothing new. Groundbreaking research from Christine Drea at Duke Universitys Department of Environmental Anthropology has reported chemical analyses for genital and shoulder scent glands for both sexes and across seasons, shaping our understanding of lemur behavior and social order. But unlike the greasy paste from shoulder glands, wrist glands produce small volumes of fast-evaporating clear liquid. Analyzing that volatile wrist cologne has been difficult, and decoding its contents was a long time in the making.

About 10 years ago, one of the co-authors, [Isao] Munechika was actually kind of living with the lemurs at the [Primate Research] Institute, says Kazushige Touhara, a Professor at the University of Tokyo and the studys lead author.

According to Touhara, Munechika was puzzled by the lemurs tail-wafting behavior. Touhara, an expert in the chemistry behind animal odors, stepped in with advanced methods in chemistry.

Over the course of seven years, the team painstakingly collected the tiny amounts of clear liquid from male lemur wrists. Each sample measured about 1/1000th of a tablespoon. It takes time to collect samples, Touhara said. And to get the secretion from the wrist, you have to have a really good relationship with the animals.

Male lemur antebrachial (wrist) gland

Kyoto University (CC BY)

Using a chemical analyzer tailored for volatile odors, the team succeeded in capturing the elusive volatile components found in male lemur wrists throughout each year. They learned that levels of three fruity and floral smelling chemicals spring up during breeding season. At least two of these molecules, tetradecanal and dodecanal, are known to affect sexual behavior in insects.

But are these chemicals actually important for lemur sexual behavior? Maybe. The new study's findings suggest that increased levels of testosterone lead to increases in these particular chemicals. And female lemurs may have a nose for them too. After the researchers added the three chemicals to a cotton pad, female lemurs seemed very interested curiously sniffing the cotton pad more during the breeding season than non-breeding season.

Some may be tempted to hype the findings as the first time pheromones have ever been seen in primates. The word "pheromone" can carry a lot of weight. Pheromones may be useful for conservation of some insects, but applying that idea seems even more distant of a plan for lemurs endangered from habitat loss (deforestation). Scientists have pondered about the existence of human pheromones. But experts are reluctant to use that label. Im not saying that lemurs dont have pheromones, said Drea, who is unaffiliated with the study. But I am saying that this paper is not demonstrating that they do.

Defining a pheromone can be tricky and arbitrary. Drea, the Duke University anthropologist who studies mammals, likens it to drawing a line in the sand. Tristram Wyatt, a Senior Research Fellow of Zoology at the University of Oxford studies pheromones across the animal kingdom. Wyatt is also careful and methodical about the term.

When you say something is a pheromone, there are a number of things that follow from that, said Wyatt. The problems come when were studying pheromones in new species particularly in mammals. With most mammals, there is a lot we dont know about the senders odor and the receivers nose and behavior.

Asked whether this studys results could be the first recorded primate pheromones, Wyatt was cautiously optimistic. These are really promising candidates, and weve not had those before, Wyatt said, But what we dont know at this stage, is that it actually affects anything to do with sex.

Family of ring-tailed lemurs

Daniel C. Devor (CC BY)

Touhara seemed to agree. We dont know what happens after the female is interested in this odor, he said. So we have to really show that this enhances mating to be able to say that this is definitely a pheromone.

Actually getting that evidence with ring-tailed lemurs means that future research should go beyond testosterone injections and female sniff tests. According to Drea, controlling lemur testosterone levels (up or down) is an established research practice, but long-term hormonal manipulation would require an implant. On the female side of things, prolonged sniffing during breeding season may seem like sexual attraction, but it doesnt prove it. Researchers need to show that this fruity mixture of molecules specifically leads to more mating.

In humans, that sort of chemical communication is unlikely. Touhara doesnt believe human sex pheromones exist, despite the fact that the human sense of smell is better than previously thought.

Using his own nose, though, Touhara smelled the lemur wrist secretion for himself. Pretty good, actually, he said, laughing. This was kind of one of the surprising results.

Similar signaling chemicals from mice are stinky, but Touhara was pleased to find the lemurs scent to smell like pears. These anecdotes may not prove any science about the lemurs, but they add to a colorful history of humans making sense of the sights and smells around us.

Wyatt shared the story of French entomologist, Jean-Henri Fabre. In the 19th century, Fabre noticed male moths would fly long distances to find females. But that attraction seemed to fall apart when the female moths sat in a sealed glass container.

And [Fabre] almost nailed it, that it must be an invisible chemical signal it must be smell, said Wyatt, tickled by the twist to come. And then he makes the mistake of sniffing the female, and he cant smell anything. So he says, Well it cant be the sense of smell...And that set back pheromone research about a hundred years.

Link:
Chemists are decoding the fruity scent of lemur stink flirting Read now - Massive Science

A study conducted by Chinese researchers in February had suggested that men are more likely to contract with coronavirus compared with females. The study report also revealed that 68 percent of the people infected with COVID-19 were males. Now, a top researcher has revealed that the most probable cause that increases the susceptibility of men to coronavirus infection is the testosterone level in the male body.

Why are men at risk of coronavirus infection?

Daniel Kelly, a lecturer in biochemistry at the Sheffield Hallam University, believes that testosterone plays a crucial role in elevating the risk of coronavirus among men. It should be noted that testosterone is the male hormone, while oestrogen dominates the female body. Several previous studies had claimed that elevated levels of testosterone in a male body will negatively affect the person's immune system.

"One theory is that the male sex hormone, testosterone, has a dampening effect on the immune system, making men more susceptible to the novel coronavirus. But just how plausible is this theory? An overview of the scientific evidence suggests that oestrogen can improve the immune system and increase immune inflammation whereas testosterone (the male sex hormone) reduces or dampens the response. As a result, women often have less severe infections than men and have significantly stronger immune responses to vaccinations," wrote Kelly in a recent article published in The Conversation.

However, Kelly revealed that coronavirus could lower the testosterone levels in a male body, but still men are at a higher risk of contracting the virus. Theoretically saying, lower testosterone levels should actually increase the immunity of the person, but the body will not be wishing to alter the hormonal level, especially while fighting a deadly disease.

Factors that increase risk of getting infected with coronavirus

As per Kelly, underlying conditions in a human body have direct impacts in determining the severity of coronavirus infection. The researcher also made it clear that age is another factor that elevates the chances of mortality after getting contracted with COVID-19.

"A major factor in how severe infection may become is whether a person has an underlying disease. While this is easy to understand, what is not so clear is the effect that the reduced levels of testosterone that happen during illness have on the likelihood of the infection developing into something more severe in men. As men age, their testosterone levels decrease, offering the possibility that increased severity of infections in elderly men may be due to lower levels of testosterone rather than simply the presence of testosterone" added Kelly.

Link:
Does testosterone increase chances of getting infected with coronavirus? Expert answers - International Business Times, Singapore Edition

You may have heard of a little company called Oculus

in the last year or two or their new headset called the Oculus Quest. If youre familiar with VR feel free to skip right to the next paragraph, but for those of you who arent, quick backstory. Oculus began as a small studio with the idea of bringing head-mounted displays to the mainstream market (keep in mind they were to be the first to do this). After launching their first prototype the DK1, Facebook, another small company you may have heard about, decided to give them some money and by some money, I mean 2 Billion dollars, and by giving some money I really mean they acquired the whole studio along with the name. You can read more about the acquisition on TechCrunchs website here.

Facebook believing in the future of VR for a long time was a bit of a joke in the industry. Ever since HTC came out with the Vive, it smoked the original Oculus Rift into the ground in a lot of ways. But now things are different. Times have changed and the race for ultra-powerful, pc-tethered, high resolution headsets is taking a bit of a side-step in terms of goals. Enter the Oculus Quest. Facebooks new version of what VR should be: No cables, no PC, just wireless fun. So lets take a look and see how they did.

As a bit of a PC-VR purist, I really wanted to hate this headset when it first came out. Let me explain. The Oculus quest has been out for about two months now and I wanted to give you my thoughts on it because it does some things really well that the PC-based headsets do, but it also lacks a few major features which, for the price point is understandable. To start this off I want to talk about my a couple favourite things about the headset and then Ill talk about the stuff that I dont really love.

First things first, I want to talk about the quality of the panel because I was actually really surprised about this coming from an HTC Vive and using the Vive Pro as well as the new Valve Index. I was expecting this headset to have lots of screen door effect, be not that high resolution and the frame rate to be really bad. And honestly even though this panel is only 72 Hertz, its actually really not that noticeable in most games.

The fact that I can play on a 72 Hertz panel versus a Vive and just go back and forth and not really care about the differences, that really means that the Quest is doing something really well. There are some experiences in which you start to notice a few hiccups in the performance but the display itself is is phenomenal. Its really sharp, the colors are amazing and the refresh rate honestly is more than adequate. If any of you are worried that because the Quest starts at $399 the display nut might not be that good, prepare to be surprised because this thing is quite awesome.

The second thing that I love about the Oculus Quest is obviously the six degrees of freedom (6DOF). If you are unfamiliar with VR Ill try to keep this short: Six degrees of freedom basically means that if I take a real step in real life it moves me one step in the game. If youre crouching, dodging and shooting around using controllers to map your hands out, it tracks all of that. Six degrees of freedom has usually been solely locked to computer based VR. You had to set up 2 sensors for the Vive, and 2 or 3 on the Oculus Rift just to build out your space to play. Its been a huge deal for a long time and its been a big inhibitor for a lot of people just getting into VR; they cant dedicate a space to it.

The amazing thing about the Oculus Quest is that you can literally just put on the headset and the four ultra-wide cameras look at the space figure around you and figure out where the walls and floor is. You literally just draw a circle on the floor and it just boots up the game. Its absolutely amazing and the fact that it remembers five spaces, you can go to your friends house and if it detects the same space you drew last time you were there, it will pop you right back into the game. I think thats such a big deal because a lot of people are really scared to get into VR because its so intimidating due to all the setup and all the hardware costs.

The six degrees of freedom on the Quest is absolutely awesome in terms of quality. Theres barely ever any tracking issues. Obviously if youre outside or something like that theres some issues, you have to play in the shade. The only time Ive ever had a tracking issue is with the controllers but well talk about that in a little bit. In terms of the headset rotation and tracking, Its been rock solid for me and I absolutely love that.

The third thing that I love about the Quest is the speakers and I know that sounds really silly but coming from a PC-based VR headset. The fact that I had to put on headphones and I would get completely isolated from the outside world is one of those things that its fun but you just get so hot. You have your earphones on, your headset on, it gets hot and you just lose yourself. The fact that the Quest allows you to put the headset on and it starts playing sound around your ears is awesome. Ive been able to play and have conversations with people without a problem.

I was recently letting my parents and my grandparents try the headset and I was able to talk to them and tell them things that they might not have otherwise heard. So when theyre playing Beat Saber and theyre stepping too far forward, I can just say, Hey, take a quick step back and they do because they can still hear you. Its honestly such a big deal for them and the fact that the sound comes straight into your ears, its pretty close to surround. Theres a few times where Ive been like whoa someones behind me and it really helped me position the enemy.

I was pleasantly surprised by the speakers on the Quest and I have not once plugged in headphones ever and I dont think that I will be. For the most part, if youre playing in a loud environment then obviously youll probably want some headphones, but the nice thing is you can just pop them in either headphone jack on the side of the headset. I think this is probably my favourite, most underrated feature of the Quest. Theyre not amazing sounding unfortunately, and it would be awesome if they were better, but theyre just tucked away in the head strap so Ill take a little bit lower quality for not having to put on hot, sweaty headphones

The last big thing that I love about the Quest is the quality of the games. Now you might be like, Wait wait wait wait wait This is basically running a phone processor(its a Snapdragon 835), what do you mean you like the quality of the games? You said you come from high-end PC-based VR running GTX1080s?

I understand the skepticism but the amazing thing about the Quest is that I ultimately didnt care about the quality of the games and thats the big thing here. If you are a hundred percent purist and need the highest quality games, as in youre that guy that will sacrifice frame rate for getting ultra settings then yeah this probably isnt the headset for you. As long as you set your expectations accordingly, again this is basically a phone running this headset, you have to understand that six degrees of freedom, 72 Hertz, and high resolution, something has to be sacrificed here.

Games like Sairento, which I really love, obviously takes a huge, noticeable hit in comparison to the regular game. They touted as having all new maps and stuff like but that is just because the Quest cant run the power of the old maps and it basically looks like Tony Hawk Pro Skater from 2000. Thats kind of what the the equivalent I would put that too. But I still dont care because Im jumping and flying around, Im doing backflips, Im jumping in slow motion, shooting people, I just dont care about the quality. The fact that it still runs well enough that its still immerses you is is truly forgivable.

And then theres games that because of the limited factor, kind of take that into account. Games like Rec Room which are super easy to port over and games like Journey of the Gods looks phenomenal. It is a very low-poly game but it totally works for this sort of atmosphere. Games like again SuperHot, Beat Saber, all these games that dont need high-end graphics run amazing on this headset.

Rambling thoughts aside, I really think that people really need to adjust their expectations when they come to the Oculus Quest. I really think that for the price it is such a great headset and the fact that you get six degrees of freedom and all of these games more than makes up for the fact that the quality is not quite as good.

Come back on Thursday when I talk about the things I dont like about the Oculus Quest! See you then.

If youve never tried VR before, come by our venue located downtown Toronto! Click Here to Book Now!

BOOK NOW

View post:
Reference Ranges for Testosterone in Men Generated Using Liquid Chromatography Tandem Mass Spectrometry in a Community-Based Sample of Healthy...

DENVER, April 18, 2020 /PRNewswire/ -- In response to current media stories regarding Low T Center's commitment to meeting the needs of Colorado patients during this COVID-19 Emergency, Low T Center provides the following for immediate release.

On April 9, the Colorado Department of Public Health & Environment released its 4th Updated Public Health Order (PHO) 20-24, encouraging Critical Businesses to remain open: "Critical Businesses, as defined below, are exempt, subject to certain limitations, from this PHO and are encouraged to remain open." Part C of PHO 20-24 states, "Any business . . . engaged primarily in any of the service activities listed below, may continue to operate as normal." PHO 20-24 defines a Critical Business as "Healthcare Operations, Including: . . . clinics, and walk-in health facilities . . . Medical . . . care, including ambulatory providers . . . [and] laboratory services." On April 6, 2020, Governor Polis issued Executive Order 2020 024 stating, "I direct all Coloradans to stay at home, unless necessary to provide, support, perform, or operate Necessary Activities . . . Necessary Travel or Critical Businesses as such terms are defined in PHO 20-24 . . . " The Order provides that "Necessary Activities" include . . . "Engaging in activities . . . including, but not limited to . . . without limitation, obtaining medical supplies . . . obtaining durable medical equipment, obtaining medication, [and] visiting a healthcare professional . . . " On that same day, the Governor issued an amended Executive Order D 2020 027, prohibiting voluntary or elective surgical procedures, if same could be safely postponed for at least three months.

Low T Center is a multi-specialty medical clinic with forty-six clinic locations spanning eleven states. Low T Center is not a hospital or outpatient surgery or procedure provider. It is not a gym or supplement store. Each clinic operates a certified and licensed moderately complex CLIA/COLA medical laboratory facility, which can accommodate a variety of important medical diagnostic tests. Pursuant to recently issued Department of Homeland Security regulations, Low T Center's facilities and its healthcare team members are classified as part of the Essential Critical Infrastructure Workforce.

Low T Center physicians treat chronic health diseases and conditions, as well as acute medical issues, ranging from low testosterone, to obstructive sleep apnea (a respiratory condition), to hypertension, high cholesterol, thyroid disorders, severe allergies, cardiometabolic issues, and other conditions that make men feel bad, and if left untreated, can be life-threatening. These conditions are often correlated with a serious medical condition known as hypogonadism. Hypogonadism is a clinical syndrome that results from the body's failure to produce physiologic concentrations of the hormone Testosterone.Hypogondal men require medically necessary hormone therapy to restore normal body functions. Failure to adequately treat and monitor these conditions can lead to serious problems such as heart disease, diabetes, obesity and cancer as well as adversely effecting overall well-being and quality of life. Treatment for hypogonadism is recognized as "medically necessary" by every major insurance carrier in Colorado.

Proper treatment of chronic hypogonadism requires office visits, labs, and continued therapy.For the individuals that require this therapy, interrupting, deferring or otherwise discontinuing therapy for a period of three months would lead to severe adverse effects, and place these patients at risk. Similarly, failing to provide treatment for diabetic patients, patients suffering from respiratory disorders, and serious cardiologic issues, is simply not acceptable, and would be contrary to the treatment guidelines employed at Low T Center.Remote treatment protocols are enabled for patients whose medical conditions do not require an in-person visit to the clinic.

For many of our patients, Low T Center is the sole provider of their preventive and primary care services. As noted above, in addition to having extensive clinical and research experience in diagnosing and treating hypogonadism, Low T Center also provides vital and continuous life-saving evaluation, diagnosis, treatment, and control of a variety of chronic, serious, and potentially life-threading disorders including cardiometabolic health, obstructive sleep apnea, hypertension, cholesterol disorders, metabolic syndrome, diabetes, and other chronic men's health issues including cardiovascular risk assessment and prevention. Because of the nature of the practice, many patients require close follow-up including appropriate physical exams as well as critical laboratory services, that if delayed "for a minimum of three months" would place these patients at "undue risk to both the current [and] future health of the patient." The treatment programs for these chronic, progressive and potentially fatal conditions (if not appropriately diagnosed, managed, and treated) are evidence- and guideline-based using the most recent literature and approaches and have been developed by a protocol committee comprised of medical school faculty and Harvard-trained distinguished leaders in their respective fields.

Consistent with Executive Order D 2020 027, these important primary care assessments and treatments cannot be delayed (as with any primary care office) as there would be 1) "a threat to the patient's life," 2) "a threat of permanent dysfunction of an extremity or organ system," (e.g., chronic limb ischemia risking amputations or progression of chronic kidney disease or heart failure.) These conditions require close physical and laboratory follow-up and monitoring of both the disease as well as the response to therapy. Furthermore, there is 3) "risk of . . . progression" particularly of the target organs of hypertension, cholesterol disorders, and diabetes manifesting as preventable strokes, heart attacks, limb damage, blindness, kidney failure, and heart failure - all of which require close medical management and adjustment of medical therapy to prevent.

Executive Order D 2020 027 rightly lets "the doctor make the decision," by granting the "treating medical facility" the exclusive discretion to determine whether a three month delay or interruption in treatment would risk the health of the patient. It would be unfortunate indeed that a hypertensive Coloradan would die, because the access to the care he needed, was postponed for three months. The Governor's Order expressly recognizes this principle, by leaving the classification of "voluntary" to the patient's medical professionals.

Low T Center does not believe Governor Polis' Order prohibits Coloradans from obtaining medically necessary treatment for diabetes, hypogonadism, hypertension, hypercholesterolemia, receiving allergy antigens, obtaining medical laboratory testing, receiving treatment for thyroid disorders, obtaining continuous positive airway pressure devices for the treatment of respiratory conditions, or any of the other medically necessary services provided to patients at Low T Center healthcare facilities. The Order uses the words "without limitation" which means Low T Center's patients should have the right to visit their healthcare provider - without limitation, for these important continuing care services.By signing the Order, Governor Polis assured Coloradans that they would be able to continue to receive their medical care during this time, by expressly classifying these activities as "Necessary Activities." Low T Center physicians, nurse practitioners, and medical staff are persons involved in operating a Critical Business which are necessary to help patients with these Necessary Activities.

Also, very relevant to the current COVID-19 crisis, outpatient centers like Low T Center significantly reduce the likelihood of requiring care in both Emergency Departments and acute care hospitals - where patients may have enhanced risk of both contracting SARS-CoV-2 and developing a potentially life-threatening and/or fatal complication of COVID-19.

Finally, Low T Center's protocol committee has mandated a series of workplace safety initiatives designed to implement social distancing guidelines. The clinic operational teams continue to adhere to enhanced cleaning and sterilization protocols. Sick persons or those exhibiting any COVID-19 like symptoms are prohibited from coming to work, but may work from home in some situations. Consistent with good medical practice, all team members are required to wash hands and use hand sanitizer between each patient visit in increasing frequency throughout the day. Patients are educated about covering coughs and sneezes, and recognizing signs or symptoms associated with COVID-19.

Low T Center's healthcare team members recognize their role as healers, and status as members of critical infrastructure, and are committed to remaining available to protect patients' rights, while adhering to all public health orders and directives issued in this state.

Media contact:David J. Moraine, J.D., M.A., LL.M. Chief Legal Officer, david@mailproglobal.com 469-990-3626

Read more:
Low T Center Is Committed To Meeting The Needs Of Colorado Patients During The COVID-19 Emergency - The Grand Junction Daily Sentinel

Freddy McConnell is a transgender man whose pregnancy was the subject of the film "Seahorse."Photo: Manuel Vazquez for "Seahorse"/Promotional image

A recent study from a fertility clinic in Massachusetts has found that transgender men who stop taking testosterone (T) had similar egg yields to cisgender women.

Boston IVF is a fertility clinic and research center, and they decided to look at years of data they had collected to see if T had a permanent effect on fertility, even after a transgender man stops taking it.

Related: How a transgender dad won the right to be the legal father of the child he carried

They found that about half of transgender men who wanted to become pregnant were undergoing hormone replacement therapy (HRT) before they tried to get pregnant. Those who were taking it stopped on average four months before undergoing ovarian stimulation cycles as part of an in-vitro fertilization process.

And they had similar egg yields to cisgender women who never took testosterone.

The landmark study involved data from 25 transgender men.

The numbers were very small, but it was very reassuring that even though these transgender men had taken testosterone, when they stopped it and were treated, they responded well and we had good outcomes, Boston IVF Medical Director Dr. Samuel Pang told NBC News.

The studys results flies in the face of the conventional wisdom that transgender men need to freeze eggs before starting T in order to one day have children.

Emmett Hardiman said that he knew he was transgender since he was young and he started HRT when he turned 18. He thought that he was definitely going to be infertile.

I had to make a choice, he said.

But his period started again several years later when he stopped T due to a lack of insurance. He had eggs harvested and his wife carried two children who came from those eggs. (Fertility experts recommend trans men go off hormones to collect and freeze eggs, although one 16-year-old trans boy reportedly was able to have eggs harvested without going off hormones.)

Dr. Pang said that even though its possible for trans men to go off HRT to have a child, that can still be asking too much.

The thought of stopping testosterone or going through hormone treatments if very daunting for them, so they frequently will not pursue it because of that, he said.

Just having to go off testosterone in order to do IVF was not a great option, but it was, to me, better than the alternative, said Hardiman.

The study looked at transgender men who started HRT as adults. Dr. Johanna Olson-Kennedy, medical director of the Center for Transyouth Health and Development at Childrens Hospital Los Angeles, said that it would probably be different for trans men who took puberty blockers and then moved directly on to T since their reproductive organs never matured.

We dont know because no one has ever done it, she said. It stands to reason that somebody would, because your hypothalamus doesnt change.

See more here:
Trans men who have been on testosterone can still be fertile - LGBTQ Nation

Erectile dysfunction may be an early warning sign of broader health problems. That's the suggestion from a new retrospectiveanalysisof European men, which found that erectile dysfunction and other sexual symptoms were associated with a greater risk of death, independent of testosterone levels.

Similar studies have shown links between mortality and sexual dysfunction, or between mortality and testosterone level, but the current study is unique,Leen Antonio, MD, PhD,assistant professor of endocrinology at Katholieke Universiteit Leuven (Belgium), said in a presentation during the annual meeting of the Endocrine Society, which was presented online this year. The actual meeting, scheduled for March 28-31 in San Francisco, was canceled because of COVID-19 concerns.

"It's the first time we have put both together in the same group of people, and we can say that it's mostly the sexual symptoms that are predicting the mortality risk, independent of the testosterone levels of these men," Dr. Antonio said in an interview.

"We can regard sexual symptoms as a marker for adverse health status in general. It's like a warning signal that you're at risk for more severe problems," Dr. Antonio added.

Dr. Antonio advised clinicians to test blood pressure and cholesterol levels in men presenting with sexual dysfunction and to counsel lifestyle changes, such as physical activity and weight management. "These can be beneficial for sexual symptoms and for general health and the risk for cardiovascular disease in the future."

Although the study could not identify a reason for the relationship between sexual dysfunction and mortality, Dr. Antonio hypothesized that the narrow penile artery may be more likely to suffer noticeable effects in the early stages of atherosclerosis, before clinical effects occur in the coronary artery.

Michael Blaha, MD, professor of medicine and director of clinical research at the Ciccarone Center for the Prevention of Heart Disease at Johns Hopkins University, Baltimore, who has studied erectile dysfunction (ED) and its association with cardiovascular disease, said that the study is further evidence that ED is an important and independent risk factor for cardiovascular disease and other health risks. He would like to see a move toward establishing men's health clinics, where risk factors can be identified and mitigated through lifestyle changes and therapies.

"There needs to be a complete rethink of the way we approach the whole group of patients who present with erectile dysfunction to various specialists," he said in an interview, noting that middle-aged men often present to ED specialists after years of not having any contact with the health system. In that group, ED can be an early warning sign that could trigger broader interventions.

"This points to the need for more men's health clinics that are focused on the early detection of risk factors, and treating erectile dysfunction and other risk factors in a more comprehensive way," said Dr. Blaha, who was not associated with the study.

Dr. Antonio and colleagues studied 1,913 community-dwelling men, who participated in theEuropean Male Ageing Study. Baseline information on sexual function and testosterone levels was collected between 2003 and 2005. The men were aged 40-79 years at study entry, and "because of the wide age range at study entry, age was used as time scale, instead of years since inclusion adjusting for age," the researchers explained.

Over a mean follow-up of 12.4 years, 25.3% of participants died. Body mass index was higher in men who died (P= .002), but there was no significant difference in smoking status. Both groups had similar levels of total testosterone, but free testosterone was lower in the deceased population (270 pmol/L vs. 312 pmol/L;P< .001), whereas luteinizing hormone levels were higher (7.8 units/L vs. 5.7 units/L;P< .001).

The lowest quartile of free testosterone level was associated with higher mortality risk (hazard ratio, 1.43;P= .021), whereas the highest quartile of follicle-stimulating hormone was associated with greater mortality risk (HR, 1.38;P= .036). There was no association between mortality risk and total testosterone or estradiol.

Men reporting three sexual symptoms at baseline had a higher mortality risk than those reporting no symptoms (HR, 1.77;P< .001). There was an association between mortality risk and ED (HR, 1.40;P= .001) and poor morning erections (HR, 1.30;P= .012), but not low libido.

The associations were not affected after adjustment for total testosterone or free testosterone. Among men with normal total testosterone (>12 nmol/L), sexual symptoms were associated with heightened mortality risk (HR, 1.51;P= .003), and the same was true in men with total testosterone levels of less than 8 nmol, compared with men with normal total testosterone who reported no sexual symptoms (HR, 1.92;P= .035).

The European Male Ageing Study received support from the European Union. Dr. Antonio has no relevant financial disclosures. Dr. Blaha has received grants from Amgen and is on advisory boards for Amgen and other pharmaceutical firms. Dr. Antonio and her team's research will be published in a special supplemental issue of the Journal of the Endocrine Society. In addition to a series of news conferences on March 30-31, the society will hostENDO Online 2020during June 8-22, which will present programming for clinicians and researchers.

SOURCE:Antonio L et al. ENDO 2020,Abstract OR02-06.

This article originally appeared on MDedge.com.

Go here to read the rest:
Erectile Dysfunction: It's Worse Than You Think - Medscape

Three chemicals with floral, fruity scents are likely essential ingredients in the natural cologne male ring-tailed lemurs use to attract a mate. Experts in odor communication say these chemicals could be the first fully identified sex pheromones in primates.

During the yearly breeding season, male lemurs rub glands on their wrists against their fluffy tails and then wave their tails at females, a behavior called "stink flirting." Only ring-tailed lemurs (Lemur catta) have these wrist glands and exhibit "stink flirting" behavior. The wrist glands produce a clear liquid, never before examined in detail.

"What made our study different is that we have expertise in chemistry, while most studies of animal communication are done by ecologists," said Professor Kazushige Touhara, an expert studying olfaction, the sense of smell, at the University of Tokyo and leader of the recent research study, published inCurrent Biology.

Recipe for lemur cologne

Researchers collected the clear liquid from males' wrist glands during both the breeding and nonbreeding seasons, then analyzed its chemical components.

The analytical technique gas chromatography-mass spectrometry can identify chemicals based on their electrical charge, molecular weight and other aspects. The research team also benefited from newer technology that can analyze small samples without complicated pretreatment.

Three odor compounds (dodecanal, 12-methyltridecanal and tetradecanal) were more abundant and one (acetamide) was less abundant in the wrist gland liquid collected during the breeding season.

Male lemurs' testosterone levels are naturally higher during the breeding season and at younger ages.

When researchers artificially increased the testosterone of a healthy, young male lemur during the nonbreeding season, the amount of the odor compounds tended to increase, similar to breeding season levels.

"This increase really supports the connection between testosterone and these odor compounds," said Project Assistant Professor Mika Shirasu, a member of the Touhara lab and co-first author of the research publication.

Females' sniff test

Researchers also saved males' breeding season wrist gland secretions to soak in cotton pads and present to females during the nonbreeding season.

"Outside of the breeding season, females had no special interest in any of the male odors we tested," said Shirasu.

To discover if any of the three odor compounds are more important for attracting females' attention, researchers presented females with cotton pads soaked in the individual odor compounds, a blend of the three compounds to mimic normal male breeding season wrist gland secretions, or a neutral control liquid.

When tested in their normal social environment, female lemurs showed no increased interest in any of the three individual male odor compounds. The more natural blend of the three compounds did capture their interest, measured as a longer time spent sniffing that cotton pad.

Although researchers can observe female lemurs' interest, the outcomes of that interest are more complicated to study.

"Curiosity does not necessarily mean sexual attraction. We cannot say for certain yet if a female spending a longer time interested in the scent means that a male will be more successful at mating," said Touhara.

Fragrance for lemurs only

It remains impossible to predict what the three likely lemur sex pheromones might mean for other primates, including humans.

"There are no humans waving tails at each other," said Touhara.

Lemurs are part of a different evolutionary lineage called the wet-nosed strepsirrhines, which have a greater sense of smell than the dry-nosed haplorhine group that includes humans and apes.

"Maybe there are no sex pheromones in humans, but there are probably odors - like parents smelling their baby's heads - that we use to affect each other's emotions," said Touhara.

Researchers cannot yet refer to the odors identified in lemurs as official sex pheromones due to the scientific definition that a pheromone must be used for communication only between members of a single species. The research team hopes that ecologists and zoologists may be able to use these new details about likely sex pheromones to increase understanding of primate behavior.

This research project was conducted over seven years, led by the University of Tokyo in collaboration with partners at Kyoto University, the Research Institute of Evolutionary Biology and the Japan Monkey Centre.

Follow this link:
Odor experts uncover the smelly chemistry of lemur love - Jill Lopez

Testosterone Replacement Therapy Market: Industry-leading Insights

The Testosterone Replacement Therapy Market report examines the growth rate and the market value by taking into consideration essential market dynamics and growth-inducing factors. While drafting the Testosterone Replacement Therapy Market report, critical market elements that the authors have taken into account are market size, share, value, current market scenario, latest technological advancements, product innovation, product launches, and expansion tactics adopted by the leading players functioning in the industry.

Industries and markets are ever-evolving, and you can navigate through these changes with the help of this research study undertaken by Market Expertz. The report includes industry-leading information and insights pertaining to the Global Testosterone Replacement Therapy Market. Browse through the detailed table of contents for the Testosterone Replacement Therapy Market Report or get a Sample [emailprotected]

https://www.marketexpertz.com/sample-enquiry-form/99936

Competitive Landscape: Global Testosterone Replacement Therapy Market

The Global Testosterone Replacement Therapy Market is highly consolidated, and the leading players in the industry have undertaken strategic initiatives, including product launches, regional expansion, agreements, joint ventures, partnerships, mergers and acquisitions, and others to strengthen their presence in the global industry. The research study encompasses the market shares held by the major regions in the Testosterone Replacement Therapy sector viz., North America, Europe, Asia Pacific, Latin America, and the Middle East & Africa.

The report gives elaborate company profiles of the leading players in the industry by reviewing the financial standing of the company and their recent performance in the market. Every company is analyzed based on gross revenue, growth rate, and profit margin to understand the markets historical development over the past three years, and an investigation of the strategic initiatives including mergers & acquisitions, product launches, and funding activity, among other essential factors.

The report studies the prominent players engaged in the industry including:

AbbVieEndo InternationalEli lillyPfizerActavis (Allergan)BayerNovartisTevaMylanUpsher-SmithFerring Pharmaceuticals

Buy the complete Global Testosterone Replacement Therapy Report [emailprotected]

https://www.marketexpertz.com/checkout-form/99936

Report analyzes the latest information pertaining to the micro- and macro-economic indicators influencing the market in the forecast years, highlighting the drivers and constraints operating in the market. The study gives an extensive statistical analysis that quantifies the critical market information, along with valuable insights into the future of the market derived through interviews of industry experts and consultants.

Market segmentation of the Global Testosterone Replacement Therapy Industry based on Product Types:

GelsInjectionsPatchesOther

Market segmentation of the Global Testosterone Replacement Therapy Industry based on Major Applications/End users:

HospitalsClinicsOthers

Market segmentation of the Global Testosterone Replacement Therapy Industry based on Geographical Break-down:North America, Europe, Asia-Pacific, Latin America, and Middle East & Africa

To get a detailed understanding of the market, the study provides a comparative market share revenue analysis (Million USD) by leading players and market shares (%) held by the leading players, along with a qualitative evaluation of all players has also been provided to decipher the market concentration rate.

To inquire about report customization, click [emailprotected]

https://www.marketexpertz.com/customization-form/99936

Some key market features and major highlights from the report:

1) Which prominent companies have been profiled in this study? Can the list of companies be customized subject to the regional markets we are targeting?

Yes, the list of companies can also be tailored as per your requirements or your areas of interest and can even include the emerging players from the targeted geographies.

** The companies covered by the report may be different in the final report subject to factors such as change of name, mergers & acquisitions, or other such activities based on the difficulty of survey since data availability will need to be confirmed by the research team especially in case of privately-held companies. Up to two companies can be added at no additional cost.

2) What is the regional coverage of the report? Is it possible to add specific countries or regions of interest?

Currently, the research report focuses on the regions of North America, Europe, Asia-Pacific, Latin America, and Middle East & Africa. Yes, it will be possible for the researchers to give information pertaining to specific regions as per your research needs.

3) Can the market be segmented based on applications or product types?

Additional segmentation/Market breakdown is possible depending on data availability, feasibility, and timeline, among others. However, a detailed list requirement is to be provided to the researchers before making any final confirmation.

**Additional countries subject to your interest can be included at no extra cost based on a feasibility test undertaken by our team of expert analysts to examine your requirements and will accordingly determine the time of delivery.

Request For Free Sample Copy of Testosterone Replacement Therapy market report for complete list of company profile, product and application

https://www.marketexpertz.com/sample-enquiry-form/99936

To study the market dynamics of the Global Testosterone Replacement Therapy sector, the report looks at the leading regions for the Testosterone Replacement Therapy industry. This market intelligence study also offers customization of the regions in the geographical assessment of the market, which covers the regions of:

In this study, the years considered to estimate the market size of Global Testosterone Replacement Therapy are as follows:

Historical Years: 2016-2018

Base Year: 2019

Estimated Year: 2020

Forecast Years: 2020 to 2027

Key Stakeholders Covered:

For in-depth analysis of value chain and supply chain of the industry, the study draws focus on the backward & forward Integration:

Testosterone Replacement Therapy Manufacturers Testosterone Replacement Therapy Distributors/Traders/Wholesalers Testosterone Replacement Therapy Sub-component Manufacturers Industry Association Downstream Vendors

Browse complete Testosterone Replacement Therapy report description And Full [emailprotected]

https://www.marketexpertz.com/industry-overview/global-2020-testosterone-replacement-therapy-market

Key facts and figures and a detailed assessment of the Testosterone Replacement Therapy market size estimation and business opportunities are available in the full report.

Thanks for reading this article. You can also get chapter-wise sections or region-wise report coverage for North America, Europe, Asia Pacific, Latin America, and Middle East & Africa.

More:
Testosterone Replacement Therapy Market to Witness Sales Slump in 2020 Due to COVID-19| Long-term Outlook Remains Positive - Daily Science

A new growth forecast report titled Global Testosterone Cypionate Market 2020 by Manufacturers, Regions, Type and Application, Forecast to 2026 contains a full-scale analysis of the global market which highlights market dynamics, risk factors, and product specification and technological advancement impacting the global market growth. The report has mentioned detailed evaluation, elementary statistics and necessary details about the predicted period from 2020-2026. The report analyzes global Testosterone Cypionate market value, innovative development procedures in the upcoming years, SWOT analysis and competitive landscape appraisal.

Market Description:

The report estimates the market size and forecast by product, region, and application as well as market competition situation among the vendors and company profile, besides, market price analysis and value chain. The study report sheds light on the whole growth dynamics of the global Testosterone Cypionate industry, market evaluation, manufacturing approach across distinct geographies and competitive landscape analysis. Then different verticals such as product portfolio, product features, and their respective product applications are covered in the report. Overall growth prospects, development analysis, and other essential components are defined and demonstrated in the form of graphs, tables, and pie-charts.

DOWNLOAD FREE SAMPLE REPORT: https://www.marketsandresearch.biz/sample-request/21827

The report deeply explores the recent significant developments by the leading vendors and innovation profiles in the global Testosterone Cypionate market including are: Pfizer, Cipla, Sun Pharmaceutical, Teva, Perrigo, Hikma Pharmaceuticals,

On the basis of product, the global market is studied across 200 mg/mL, 100 mg/mL

On the basis of the distribution channel, the global market is studied across Primary hypogonadism, Hypogonadotropic hypogonadism, Late-onset hypogonadism

The research study has uploaded differentiable threats, the establishment of the business division, various patterns to investigate the global Testosterone Cypionate market. The report throws light on the insightful details of the leading industry players who gather high-profile contribution of the market annually. The market is fragmented on the basis of elite industry manufacturers, geographical regions, product types, and key applications. New product innovations by the industry are also talked about in the report. Further, it offers correct and dependable forecasts of the market proportion of important segments of the worldwide market.

The report offers an in-depth assessment of the growth and other aspects of the market in important regions, including the North America (United States, Canada and Mexico), Europe (Germany, France, UK, Russia and Italy), Asia-Pacific (China, Japan, Korea, India and Southeast Asia), South America (Brazil, Argentina, Colombia etc.), Middle East and Africa (Saudi Arabia, UAE, Egypt, Nigeria and South Africa). Region-wise revenue, volume, the data of production, and manufacturers for the forecast period of 2015 to 2026 are studied. These analyses will help the reader to understand the potential worth of investment in a particular region.

ACCESS FULL REPORT: https://www.marketsandresearch.biz/report/21827/global-testosterone-cypionate-market-2020-by-manufacturers-regions-type-and-application-forecast-to-2026

The Research Report Will Enhance Your Decision-Making Power by Helping You To:

Customization of the Report:This report can be customized to meet the clients requirements. Please connect with our sales team ([emailprotected]), who will ensure that you get a report that suits your needs. You can also get in touch with our executives on +1-201-465-4211 to share your research requirements.

Other Related Reports Here:

Global Natural Food and Beverage Foaming Agent Market 2020 Comprehensive Research, SWOT Analysis, Key Players and Forecast by 2026Global Natural Health Supplements Market 2020 Comprehensive Research, SWOT Analysis, Key Players and Forecast by 2026Global Natural Humectants Market 2020 Comprehensive Research, SWOT Analysis, Key Players and Forecast by 2026Global Natural Lecithin Market 2020 Comprehensive Research, SWOT Analysis, Key Players and Forecast by 2026Global Near-infrared Spectroscopy Market 2020 Comprehensive Research, SWOT Analysis, Key Players and Forecast by 2026

Link:
Global Testosterone Cypionate Market 2020 by Manufacturers, Regions, Type and Application, Forecast to 2026 - Germany English News

Magnifier Research published a Global Testosterone Replacement Therapy Market Report 2020, Forecast to 2025 which provides a comprehensive study on the market, comprising a nitty-gritty and fair-minded evaluation of this market. The markets segmentation and the significant market verticals are considered while evaluating its industrial chain, production chain, manufacturing capacity, sales volume, and revenue. The research is a meticulous study of the global Testosterone Replacement Therapy market which portrays each and every detail of the market. It provides an overview of market segmentation such as type, application, and region. It also lists the drivers, limitations, and opportunities available in the market.

Some well-known companies identified to operate in the global market are: AbbVie, Endo International, Eli lilly, Pfizer, Actavis (Allergan), Bayer, Novartis, Teva, Mylan, Upsher-Smith, Ferring Pharmaceuticals

Factors that are contributing to the growth of a specific type of product category and factors that are motivating the status of the market highlighted in the report. The report covers the details on market acquisitions, mergers, and significant trends that are influencing the growth of the global Testosterone Replacement Therapy market in the coming years from 2020 to 2025. During the report compilation, analysts have used established and beneficial tools and techniques such as SWOT analysis and Porters Five Forces analysis to carry out the research study. The geographical scope of the products is also taken into consideration.

DOWNLOAD FREE SAMPLE REPORT: https://www.magnifierresearch.com/report-detail/40135/request-sample

On the basis of product type, this report displays the shipments, revenue (Million USD), price, and market share and growth rate of each type: Gels, Injections, Patches, Other

On the basis on the end users/applications, this report focuses on the status and outlook for major applications/end users, shipments, revenue (Million USD), price, and market share and growth rate for each application: Hospitals, Clinics, Others

An All-Inclusive Framework of The Geographical Terrain:

The global Testosterone Replacement Therapy market report covers market shares for global, North America (United States, Canada and Mexico), Europe (Germany, France, UK, Russia and Italy), Asia-Pacific (China, Japan, Korea, India and Southeast Asia), South America (Brazil, Argentina, Colombia etc.), Middle East and Africa (Saudi Arabia, UAE, Egypt, Nigeria and South Africa). The analysis of this report has been used to examine various segments that are relied upon to witness the quickest development based on the estimated forecast frame. Moreover, data concerning growth opportunities for the market across every detailed region is included in the report. The anticipated growth rate expected to be recorded by each region over the estimated years has been given within the research report.

ACCESS FULL REPORT: https://www.magnifierresearch.com/report/global-testosterone-replacement-therapy-market-report-2020-forecast-40135.html

Opportunities in The Global Testosterone Replacement Therapy Market Report:-

Customization of the Report:This report can be customized to meet the clients requirements. Please connect with our sales team (sales@magnifierresearch.com), who will ensure that you get a report that suits your needs. You can also get in touch with our executives on +1-201-465-4211 to share your research requirements.

About Us

Magnifier Research is a leading market intelligence company that sells reports of top publishers in the technology industry. Our extensive research reports cover detailed market assessments that include major technological improvements in the industry. Magnifier Research also specializes in analyzing hi-tech systems and current processing systems in its expertise. We have a team of experts that compile precise research reports and actively advise top companies to improve their existing processes. Our experts have extensive experience in the topics that they cover. Magnifier Research provides you the full spectrum of services related to market research, and corroborate with the clients to increase the revenue stream, and address process gaps.

Contact UsMark StoneHead of Business DevelopmentPhone: +1-201-465-4211Email: sales@magnifierresearch.comWeb: http://www.magnifierresearch.com

See original here:
Global Testosterone Replacement Therapy Market 2020 Regional Analysis, Growth Prospects, Size, Outlook and Forecast 2025 - Galus Australis

Page 67«..1020..66676869..8090..»

Home » Testosterone » Page 67