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Apr 6

Comparative efficacy of statins, metformin, spironolactone and combined oral contraceptives in reducing testosterone levels in women with polycystic…

A total of 281 articles were identified in the systematic search, and among these 9 articles were included in the network meta-analysis. The flowchart in Fig. 1 illustrates the process of including and excluding articles for this systematic review and network meta-analysis. The included studies were described in Table 3 [1,2,3,4,5,6,7,8,9].

Flow diagram for study selection

The interventions in the included studies were COCs, atorvastatin, simvastatin, spironolactone, simvastatin plus metformin (SmivMet), metformin plus spironolactone (MetSpiro), metformin alone, and placebo. There was a direct comparison between atorvastatin and placebo and between simvastatin and metformin; however, no trials made a direct comparison between statins and other therapies. Therefore, a network meta-analysis deemed necessary to provide an indirect comparison between the interventions (Fig. 2). The summary of the results from the inconsistency test and the quality assessment of the included studies and risk of bias table were provided respectively in Table S1 and Figures S1 and S2 of the supplementary material.

Network plot of all interventions in the analysis

Metformin was the only management strategy that was evaluated directly to most of the other strategies. When compared to metformin, the pairwise comparison showed no significant difference in reducing the testosterone level for all management strategies. The results from the pairwise meta-analysis are presented in Table 4 above the leading diagonal.

In the network meta-analysis, atorvastatin showed greater reduction in testosterone level compared to COC (MD 2.78, 95%CrI 3.60, 1.97), spironolactone plus metformin (MD 2.83, 95%CrI 3.80, 1.87), simvastatin (MD 2.88, 95%CrI 3.85, 1.92), spironolactone (MD 2.90, 95%CI 3.77, 2.02), simvastatin plus metformin (MD 2.93, 95%CrI 3.79, 2.06), metformin (MD 2.97, 95%CrI 3.69, 2.25), lifestyle modification (MD 3.02, 95%CrI 3.87, 2.18), and placebo (MD 3.04, 95%CrI 3.56, 2.53). The results from network meta-analysis is presented in Table 4 below the leading diagonal.

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Comparative efficacy of statins, metformin, spironolactone and combined oral contraceptives in reducing testosterone levels in women with polycystic...


Apr 6

Why men with erectile dysfunction may face higher risk of death – Guardian

Men with erectile dysfunction have a higher risk of death, regardless of their testosterone levels, suggests a study accepted for presentation at ENDO 2020, the Endocrine Societys annual meeting, and publication in a special supplemental section of the Journal of the Endocrine Society.

As both vascular disease and low testosterone levels can influence erectile function, sexual symptoms can be an early sign for increased cardiovascular risk and mortality, said lead researcher Leen Antonio, M.D., Ph.D., of KU Leuven-University Hospitals in Belgium.

Low testosterone levels have been linked to a higher risk of death in middle-aged and older men, but results from large studies are inconsistent, Antonio said. Studies have also linked sexual dysfunction with mortality in older men.

The new study used data from the European Male Ageing Study (EMAS), a large observational study that was designed to investigate age-related hormonal changes and a broad range of health outcomes in elderly men. The researchers analyzed data from 1,913 participants in five medical centers. They analyzed the relationship between their hormone measurements and sexual function at the beginning of the study, and whether they were still alive more than 12 years later.

During the average follow-up period of 12.4 years, 483 men25 percentdied. In men with normal total testosterone levels, the presence of sexual symptoms, particularly erectile dysfunction, increased the risk of death by 51 percent compared with men without these symptoms.

Men with low total testosterone levels and sexual symptoms had a higher risk of death compared with men with normal testosterone levels and no sexual symptoms.

Men with erectile dysfunction, poor morning erections and low libido had a higher mortality risk compared to men with no sexual symptoms. In men with these three sexual symptoms, the risk of dying was almost 1.8 times higher compared to men without symptoms. In men with just erectile dysfunction, the risk of dying was 1.4 times higher compared to men without erectile dysfunction.

Levels of free testosterone (the testosterone that is easily used by the body) were lower in those who died. Men who had the lowest levels of free testosterone had a higher risk of death compared to men who had the highest levels.

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Why men with erectile dysfunction may face higher risk of death - Guardian


Apr 6

FOX’S Maria Bartiromo Honored by Her Peers as a Business News Visionary – The Grand Junction Daily Sentinel

DENVER, April 6, 2020 /PRNewswire/ --Maria Bartiromo, a trailblazer and role model for women in television financial news, has been honored by her peers for her transformative contributions to the profession.

Bartiromo is one of 52 prominent business and financial journalists named a 2020 Business News Visionary. Her oral history and profile are available now at http://www.NewsLuminaries.com and will be featured in a commemorative book to be published early next year.

"Maria has been a groundbreaker throughout her career, debunking stereotypes and demonstrating an unwavering dedication to reporting the truth regardless of who might be offended or what sacred cows she gores," said Dean Rotbart, chair and editor-in-chief of the Business News Visionary (BNVA) awards.

Bartiromo, FOX Business Network's global markets editor and a high-profile anchor on both FBN and FOX News Channel, has covered a wide range of economic, markets, political, and Main Street financial stories since joining FOX in 2014 from CNBC.

"Importantly, Maria was early among financial journalists to shift her focus from the stock market alone to include public policy and kitchen table issues into her coverage," Rotbart noted.

Growing up, Bartiromo explains in her oral history, she was inspired by role models, including Barbara Walters and Diane Sawyer, and even drew inspiration from Mary Richards, the fictional WJM-TV news producer portrayed by actress Mary Tyler Moore on her eponymous sitcom.

"These role models, women leaders, are so important to encourage other women to get confidence and strength in terms of getting into the business," Bartiromo says.

"Starting in journalism in her early 20s, Maria, herself, has evolved into a role model for women seeking to compete and excel in male-dominated professional settings, especially journalism and finance," Rotbart explained.

In August 1995, not only did Maria earn the distinction of being the first journalist to regularly broadcast live from the floor of The New York Stock Exchange, she did so at a time when as she later recounted "women were a minority on the testosterone-filled NYSE trading floor."

The Business News Visionary Awards are a continuation of The Business News Luminary Awards, which, in 2000, honored the 100 top business and financial news journalists of the 20th century.

"The goal of this project extends beyond the celebration of the specific men and women who are profiled," notes Terri Thompson, who introduces each journalist's oral history.

"It is also to educate the public about the high standards to which these and so many other dedicated journalists have adhered and to offer a proven playbook for other journalists and journalism students to follow," she says. Thompson is the former director of the Knight-Bagehot Fellowship in Economics and Business Journalism at Columbia University.

Rotbart, a Pulitzer Prize-nominated, award-winning financial journalist and former columnist with The Wall Street Journal, was the founder of "TJFR Business News Reporter," an influential trade newsletter and magazine that provided a behind-the-scenes look at business and financial journalists and their news organizations.

He, along with a panel of more than two dozen distinguished nominating judges including top business news organization editors and reporters, and past award recipients are responsible for the selection of the 2020 BNVA recipients.

A portion of the proceeds from the sale of the 2020 BNVA commemorative book and related sponsorship opportunities will benefit business journalism education and scholarship programs.

The Business News Visionary and News Luminary Awards are made possible, in part, by the generous support of Monday Morning Radio, a weekly business-to-business podcast; The Dilenschneider Group, providing an unsurpassed level of communications counsel to global clients; and Time in a Bottle Photography and its founder, Avital Rotbart, specializing in world-class portrait photography.

Media contact:Dean Rotbart237324@email4pr.com303-296-1200

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FOX'S Maria Bartiromo Honored by Her Peers as a Business News Visionary - The Grand Junction Daily Sentinel


Apr 6

Global Testosterone Replacement Therapy Market Research Report By Key Players, Geographical Regions and Growth Analysis Outlook Up To 2025 – Fashion…

Global Testosterone Replacement Therapy Market presenting the fundamental market overview, market trends, past, present and forecast data related to the Testosterone Replacement Therapy Market From 2020-2025. A complete analysis of the Testosterone Replacement Therapy based on the definition, product specifications, market gains, key geographic regions, and imminent Testosterone Replacement Therapy players will drive key business decisions.

Global Testosterone Replacement Therapy market report presents a thorough and latest market insights in the form of graphs, pie charts, tables to provide a clear picture of the Testosterone Replacement Therapy Market. Global Testosterone Replacement Therapy report is divided into different chunks based on the type, diverse applications, key geographical regions, market share of each player, their production volume, and supply-demand ratio.

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AbbVieAllerganBayerEli Lilly and CompanyKyowa Kirin InternationalNovartisPfizer

Testosterone Replacement Therapy Market Based On Product Type:

General Type

Testosterone Replacement Therapy Market Based On Product Applications:

Medical

In this study, the years examined to evaluate the market size of Testosterone Replacement Therapy are as per follows:

History Year: 2014-2019

Base Year: 2019

Estimated Year: 2020

Forecast Year: 2020 to 2025

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Section 1: This section covers the Global Testosterone Replacement Therapy Market overview, including the basic market introduction, market analysis by its applications, type, and regions. The major regions of the Global Testosterone Replacement Therapy Market include, Europe, Asia, Middle East & Africa. Testosterone Replacement Therapy Market statistics and outlook (2020-2025) are presented in this section. Testosterone Replacement Therapy market dynamics states the opportunities, key driving forces, market risk are studied.

Section 2: This section covers Testosterone Replacement Therapy manufacturers profile based on their business overview, product type, and application. Also, the sales volume, Testosterone Replacement Therapy product price, gross margin analysis, and Testosterone Replacement Therapy market share of each player is profiled in this report.

Section 3 and Section 4: These sections present the Testosterone Replacement Therapy competition based on sales, profits, and market division of each manufacturer. It also covers the Testosterone Replacement Therapy market scenario based on regional conditions. Region-wise Testosterone Replacement Therapy sales and growth (2020-2025) are studied in this report.

Section 5 and Section 6: These two sections cover the Testosterone Replacement Therapy Market by countries. Under this, the Testosterone Replacement Therapy revenue, the market share of the countries like United States, Canada & Mexico are provided.

Section 7, Section 8 and Section 9: These 3 sections covers Testosterone Replacement Therapy sales revenue and growth in all the regions. Under these regions Testosterone Replacement Therapy report covered, the growth and sales in these regions are illustrated in this Testosterone Replacement Therapy Market report.

Section 10 and Section 11: These sections depict the Testosterone Replacement Therapy market share, revenue, sales by product type and application. The Testosterone Replacement Therapy sales growth seen during 2015-2020 is covered in this report.

Section 12 and Section 13: These sections provide forecast information related to Testosterone Replacement Therapy market (2020-2025) for each region. The sales channels include direct and indirect Testosterone Replacement Therapy marketing, traders, distributors, and development trends are presented in this report.

Section 14 and Section 15: In these sections, Testosterone Replacement Therapy market key research conclusions and outcome, analysis methodology, and data sources are covered.

*** Thank you for reading. You may also request custom information, such as chapter-wise or unique region-wise research, depending on your interest. ***

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Global Testosterone Replacement Therapy Market Research Report By Key Players, Geographical Regions and Growth Analysis Outlook Up To 2025 - Fashion...


Apr 6

Double Whammy: Men With Erectile Dysfunction Also Have Higher Risk Of Death – Study Finds

LEUVEN, Belgium Talking about problems in the bedroom is never an easy task for a man. Culturally, men are inundated from an early age with the idea that the ability to perform sexually at a moments notice is a trademark quality of a real man. According to a new study, however, erectile dysfunction may represent a much bigger problem than just embarrassment.

Researchers have concluded that men with erectile dysfunction face an overall higher risk of death, regardless of their testosterone levels.

As both vascular disease and low testosterone levels can influence erectile function, sexual symptoms can be an early sign for increased cardiovascular risk and mortality, comments lead researcher Dr. Leen Antonio, of KU Leuven-University Hospitals in Belgium, in a release by the Endocrine Society.

Lower than average testosterone levels have been linked to a higher death risk in the past among middle-aged and older men, but most of the research on that topic has yielded inconclusive results. Some studies have even found an association between broad sexual dysfunction in men and a higher mortality risk.

So, in an effort to clarify these vague prior findings, the research team this time around utilized data collected as part of a large observational European study that focused on age-related hormonal changes in older men and subsequent health developments. In all, information on 1,913 men were included in the study.

For each man, researchers investigated the relationship between their hormone levels and sexual functioning both at the beginning of the observation period and once again just over 12 years later, assuming of course said participant was still alive.

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During the entire follow-up period (12.4 years), a total of 483 participants (25%) passed away. Among those fatalities, researchers discovered that men with normal levels of testosterone yet still suffering from erectile dysfunction had a 51% higher risk of dying than men with no reported sexual problems.

Additionally, men with notably low testosterone levels and sexual dysfunction symptoms had an even higher risk of death than participants with normal testosterone and no sexual symptoms.

The results were broken down in even greater detail. For example, men who reported erectile dysfunction, weak morning erections, and low sexual drive had a higher death risk than men with normal sexual tendencies. More specifically, men suffering from all three of these complaints had a 1.8 times higher risk of dying than men with no symptoms. For men with just erectile dysfunction, that risk of dying was 1.4 times higher.

Overall, men who died tended to have lower levels of free testosterone, or the testosterone that is easily used by the body.

This research is set to be presented at ENDO 2020, the Endocrine Societys annual meeting. It will also be publishedin the Journal of the Endocrine Society.

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Double Whammy: Men With Erectile Dysfunction Also Have Higher Risk Of Death - Study Finds


Apr 6

What isn’t seen isn’t heard: trans and non-binary health amid COVID-19 – The CT Mirror

March 31 was International Transgender Day of Visibility. Minus a few posts online by media outlets, little was said about it this year. As a public health student, I have been wondering how marginalized communities will be negatively affected by COVID-19 and how some communities needs will be overshadowed as healthcare systems become overwhelmed and medical resources are focused on treating coronavirus patients.

Ryan Sutherland

One of the communities that will undoubtedly face increased pressure is the transgender and non-binary community as a result of restrictive coronavirus lockdowns, disrupted access to social services, barriers to prescribing and managing hormone therapy medications, and hospital decisions to halt gender-affirming surgeries.

And in some ways, stay-at-home orders and enforced social distancing policies, while they effectively reduce opportunities for viral transmission, also contribute to trans erasure and create more opportunities for the existence of members of the trans and non-binary communities to be ignored, denied or minimized. What isnt seen isnt heard, and only through increased visibility comes equal rights.

Recently, Gov. Brad Little of Idaho signed into law House Bill 500, the Fairness in Womens Sports Act, and House Bill 509, the Idaho Vital Statistics Act. H.B. 500 states that athletic teams or sports designated for females, women, or girls shall not be open to students of the male sex and that disputes can be resolved by inspecting the students reproductive anatomy, genetic makeup, or normal endogenously 19 produced testosterone levels, effectively banning female-identifying transgender athletes from performing on teams aligned with their chosen gender identity.

H.B. 509 prohibits transgender individuals from changing their gender on their birth certificates. These bills originated from complaints strikingly similar to those articulated in a recent lawsuit filed against the Connecticut Association of Schools, Connecticut Interscholastic Athletic Conference and the boards of education in Bloomfield, Cromwell, Glastonbury, Canton and Danbury aimed to block transgender athletes from participating in girls sports.

With more than 40 states that have introduced similar legislation this year, statewide stay-at-home orders and social distancing policies limit the ability for transgender activists to protest and overturn discriminatory legislation such as these bills. And the media focus on COVID-19 developments might allow this type of legislation to fall through the cracks.

Additionally, trans and non-binary workers are three times more likely to be unemployed compared to the general population, and a lack of employer-based insurance results in a disproportionate insurance coverage gap. The pandemic has only exacerbated existing disparities. The International Foundation for Employee Benefit Plans reported that transgender inclusive healthcare benefits are offered to less than one-third of U.S. employees. With widespread furloughing and unemployment in response to the pandemic, even those with insurance benefits that cover hormone replacement therapy (HRT), counseling, or gender-affirming surgery are at risk of losing coverage.

While over 3 million Americans filed for unemployment as a direct result of layoffs caused by COVID-19, applying for unemployment might create unique challenges for trans individuals who might be required to use their deadname, a name assigned at birth that has electively been changed to match their gender identity, to prove their identity on government forms this can undoubtedly be traumatizing. Furthermore, trans and non-binary individuals might be wary to seek unemployment help as waiting in long lines outside unemployment offices might put them at an increased risk of discriminatory violence.

And it is no secret that, as a result of social stigma and discrimination, the transgender population has a higher rate of unstable housing and homelessness. According to the Williams Institute, over 30% of individuals served by drop-in centers, street outreach workers, and housing programsidentified as LGBT. Unfortunately, those who are transgender and homeless are at increased risk of exploitation, violence, and abuse, and may be turned away from shelters as a result of their gender identities. As some homeless shelters close or limit occupancy to stop the spread of COVID-19, this further limits available housing options for unhoused transgender individuals.

Past negative experiences of being misgendered or refused service when seeking care or out of fears of contracting COVID-19 in healthcare settings may cause trans people to forego care. And trans individuals may be reluctant to go to hospitals and clinics to request hormone replacement therapy (HRT) treatment during the pandemic already overburdened hospitals might not have the capacity to provide sufficient social services or hormone treatments.

Furthermore, gender-confirmation surgeries, deemed non-essential and elective, have been delayed or cancelled at many U.S. hospitals due to coronavirus. Interruptions in HRT provision or postponing long-awaited gender-affirming surgeries could augment feelings of isolation and gender dysphoria and amplify psychological distress. The Trevor Projects 2019 survey reported that more than half of transgender and non-binary young people have contemplated suicide and one-third have attempted it.

The minority stress model, a social psychology theory widely adopted in public health, describes how extreme minority stress causes adverse health outcomes among stigmatized minority groups. Consistent stress, discrimination and internalized stigma faced by transgender people increases their risk of suicidality. And as health systems react to treat coronavirus patients and critical services previously available to transgender patients are interrupted or deprioritized, feelings of isolation and marginalization might further increase rates of suicide or affect transgender mental and physical health and wellbeing.

School closures might also pose unique challenges to transgender youth. With campus LGBTQ resource centers and peer support unavailable and the suspension of all school-based social activities, transgender students might feel unsupported. Furthermore, self-quarantining with abusive family members who do not affirm their trans identity can be extremely traumatizing to trans youth.

As one trans commenter pointed out on a recent Buzzfeed article, I have to make a decision about whether to stay in the UK where I study or fly back to the States to be with my parents, one of whom doesnt use my name or pronouns and has refused to do so. With campuses and dormitories closed to suppress viral transmission, some transgender students must return home to unsafe emotionally and physically abusive homes because they are left with nowhere else to go. And once there, due to enforced lockdowns, they potentially cannot leave.

Quarantine and lockdowns may also increase rates of domestic and intimate partner violence perpetuated against transgender individuals. According to conservative estimates, the National Coalition Against Sexual Violence reports that one in three women and one in nine men will experience sexual violence during their lifetime, and these estimates do not accurately capture the increased risk of sexual violence within the LGBTQ community. Lockdowns and social distancing policies, budget cuts to IPV-related social services and mental health counseling, and financial instability due to unemployment all create opportunities for abusers to perpetrate sexual violence and make it more difficult for transgender victims to leave abusive relationships or report abuse.

Lastly, conservative graphs from the Imperial College COVID-19 Response Team and others by the Centers for Disease Control and Prevention (CDC) show frightening estimates that up to 2.2 million Americans mainly older adults, those who are immunocompromised, or those who have other pre-existing health conditions such as diabetes or lung disease might die as a result of contracting COVID-19. Elderly trans individuals at higher risk of contracting COVID-19 might refuse help from aging providers such as meal delivery programs, senior centers, or other social programs because they are afraid of harassment or discrimination.

Furthermore, statistics show the LGBTQ community is 50% more likely to smoke than the general population, potentially resulting in increased susceptibility to respiratory failure brought on by COVID-19, a respiratory illness. Moreover, trans individuals are more likely than the general population to be diagnosed with cancer and HIV, and reduced immune function could put them at a higher risk to contract coronavirus and face harsher symptoms.

Overall, the coronavirus has not just affected the trans and non-binary communities by restricting access to gender-affirming surgeries or HRT, but has effectively reduced their visibility. Fears of being misgendered or mistreated when seeking unemployment benefits or care in healthcare settings may cause trans and non-binary people to forego seeking assistance during this crisis.

Disruptions in hormone replacement therapy (HRT), counseling, or gender-affirming surgeries and self-quarantining with abusive family members may increase psychological distress and can augment rates of suicidality. Widespread unemployment might result in a loss of employer-based insurance coverage of hormone therapy and gender-affirming surgeries and cause an increase in homelessness among this population. And transphobic legislation may pass in the absence of assembled protestors who remain sequestered at home due to public health efforts to stop the spread of the coronavirus.

While COVID-19 has had a pronounced effect on everyone, those most vulnerable, such as those in the trans community, are poised to receive the most collateral damage.

Ryan Sutherland is a Master of Public Health candidate at the Yale School of Public Health in the Social and Behavioral Science Department with a concentration in global health.

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What isn't seen isn't heard: trans and non-binary health amid COVID-19 - The CT Mirror


Apr 6

ur Wild Calling: How Connecting With Animals Can Transform Our Livesand Save Theirs – National Parks Traveler

They were young bulls, possibly even siblings, and their own full-fledged, testosterone-fueled combative rut was probably a full year away. Yet back and forth they jostled in our yard, testing each other not 20 feet from the backdoor, their antlers clattering against each other, steam flushing in bursts from their nostrils in the cold fall air as their gangly legs sought leverage in the not-yet-frozen ground.

Driven instinctually to demonstrate their male supremacy, the two gave and took as they shouldered their sheer bulk behind their antlers, searching for the tipping point. For more than an hour they kept at it, slowly crossing our yard, then up and over the small rise between houses, and into our neighbors yard.

Though Ive seen similar battles on nature shows, seeing one waged in person had been unimaginable until that fall day. I had grown up in New Jersey, where the visible wildlife was usually restricted to deer and birds.

But as my life took me west, I encountered more and more wild animals. Ive been treated to elk, bison, and even wolves roaming Yellowstone National Parks northern range, humpback whales in Glacier Bay National Park and Preserve, a 6-foot Western rattlesnake warming itself in the morning sun in the backcountry of Zion National Park, orcas at work schooling salmon in the waters around the San Juan Islands of Washington state.

Not everyone is so fortunate.

Roughly 80 percent of Americans live in urban areas, according to the U.S. Census Bureau. Moose dont, nor grizzly bears, or herds of bison or elk. The nations development forced thewild lifeout, into smaller, more remote parts of the country. For most Americans, that urbanization also pushed away our interaction with wildlife, our connection with the wild side of the world. It is a personal connection, one more important than many of us probably realize.

Richard Louv spent four years pondering the connection he specifically, and the rest of us in general, have with wildlife. In his 2005 bestseller,Last Child in the Woods, Louv painted a disturbing picture of how we're not just losing bits and pieces of our natural landscape to that urbanization. He underscored how we're failing our children by not working harder to introduce them to nature.

Louvs message then was that through urban sprawl, through the mesmerizing and addictive magic and wizardry of the Internet, and through fear of many of the neighborhoods we call home, we were spawning generations of kids who don't know what it's like to have warm mud squish up through their toes as they wade in creeks to catch frogs, or to hear the gentlewhooshingof a forest's canopy under the breath of the wind as they play hide-and-seek.

Today, Louv warns us that for a large segment of society, that disconnect with wildlife is multiplying our societal nature deficit. Especially today, as more and more of America is being told to stay home in a hopeful bid to stanch the viral march of coronavirus, the separation is growing. To better understand that growing void, I reached out to Louv, whose latest work,Our Wild Calling:How Connecting with Animals Can Transform Our Livesand Save Theirs, examines the importance of wildlife to humans.

It may be more necessary than I thought it would be because of the sense of isolation now people have to endure and the loneliness epidemic thats now been squared, Louv said of his book when I asked what inspired it. Our connection to other animals, even if its outside our window, is I think more important than ever.

Growing up in New Jersey, what wildlife there was was largely ubiquitous, not thought provoking. But as I left the East Coast behind, and moved closer to where the wild things are, they became more important to me, took on a larger role in my life. Knowing that there are annual migrations of thousands of caribou in Alaska is important. But more important is actually being present as herds of bison move almost as one across the Hayden Valley in Yellowstone, or to float quietly in a kayak on a finger of Glacier Bay as a humpback whale and her calf circle, occasionally surfacing to exhale a frothy breath in trade for some fresh air.

We gain meaning from these encounters with other animals, Louv told me. And with our relations with our (domestic) companion animals. But these things that happen when were with wild animals, are particularly mysterious.

Mysterious, yes, but it also triggers something within us. At least it does for me. Experiencing wild animals in their natural settings reinforces my own tie to nature. We are descended from prehistoric cultures that lived on, and from, the land, depending on it for their food and shelter. That tie resides within all of us; deeper for some than others. We are wild at heart. And Louv wants us to remember that.

Louv is ahead of most of us in understanding how impactful wildlife can be upon us, if we open our consciousness to them. Of his ten books, four have been specifically about our human connection with nature. Hes spent years analyzing our relationships, and his own, with wild animals. And he fears that our direct connections with wildlife are in decline.

The question I asked inLast Child, and in the others, is what happens to us? What happens to us psychologically, what happens to us physically, what happens to our social intelligence when we disconnect from nature? Louv asked. All of those things are involved. And what happens to our cognitive abilities? It turns out that this disconnect from nature has real implications.

You can see that disconnect in Yellowstone, Glacier and Grand Teton national parks every summer as visitors approach wildlife 2,000-pound bison and mountain goats with dangerous horns much too closely to capture a photo or a selfie. They dont see thattruly wildanimal filling their viewfinder; they envision a zoo creature, domesticated livestock. That disconnect stems simply from thinking park wildlife are somewhat tame. But the disconnect with the wild side of nature is deeper these days, and affects our understanding and appreciation of the significance of a bison herd, or a wolf pack, or a pod of orcas. For Aldo Leopold, an ecologist and nature writer in the early part of the 20th century, it took the death of a wolf to understand the connection.

We reached the old wolf in time to watch a fierce green fire dying in her eyes. I realized then, and have known ever since, that there was something new to me in those eyessomething known only to her and to the mountain. I was young then, and full of trigger-itch; I thought that because fewer wolves meant more deer, that no wolves would mean hunters paradise. But after seeing the green fire die, I sensed that neither the wolf nor the mountain agreed with such a view.

Whether we actually realize our disconnect with wildlife is something each of us has to mull. But at the end of the day, Louv believes we long for the connection.

"I think its rooted in a deeper loneliness. Which is species loneliness. The urban parks, with the highest benefit for the human psychological health, turn out to be the parks with the highest biodiversity, he told me. I dont think thats an accident. We are desperate as a species, not just as individuals, but as a species to not be alone in the universe, to not feel alone in the universe. Why else would we look for Big Foot? Why else would we look for life on other planets, intelligent life, when people like Stephen Hawkin have told us that it might not be a good idea to find?

As the human culture, we are wired to search for other life, Louv said, even when the life might be bison, or wolves, or moose.

Were surrounded by a larger family of life. We are surrounded by a great conversation going on all around us, wherever we are. Even in the densest urban neighborhood, he went on. The more we learn about other animals, the more we learn about their sentience, the more we learn about their intelligence, the more we learn about their ability to communicate with each other, and with us, between species, not only within their own species. And we can tap into that, even if were locked inside a house. If we pay attention.

Im fortunate for where I live, that I may come into contact with wildlife in the wild. Those two young bull moose tussling in the backyard reminded me of my fortune, and that wild connection.

You can listen to my entire conversation with Richard Louv in National Parks Traveler Episode 59 of our podcast series.

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ur Wild Calling: How Connecting With Animals Can Transform Our Livesand Save Theirs - National Parks Traveler


Mar 30

Global Testosterone Booster Market Growth Projections and Forecast to 2026 | Testofuel, GNC, TestoTEK, Prime Male, TEK Naturals – Skyline Gazette

Global Testosterone Booster Market report (2020-2026) studies the current market status with future trends that can affect the market growth rate and covers the major growth prospect over the forthcoming years. The Testosterone Booster market report objectives are to provide in-depth information about Testosterone Booster industry with market outlook, key trends, business plans, future prospect of the industry. It comprehends market new product analysis, financial overview, strategies and marketing trends. Testosterone Booster market report also offers an overview of revenue, sales, product demand, and supply of data, cost, and growth analysis during the forecast year. A portion of the Leading key organizations Covered for this Research isTestofuel, GNC, TestoTEK, Prime Male, TEK Naturals, TestoGen, Prime Male, Nugenix, Monster T, TestoRush.

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The research report study the market size, share, key drivers for growth, major segments, and CAGR. The Testosterone Booster market report study deep analysis about market status (2015-2020), enterprise competition pattern, advantages and disadvantages of enterprise Products, industry development trends (2020-2026), regional industrial layout characteristics and macroeconomic policies, industrial policy has also be included. Development policies and plans are discussed as well as manufacturing processes and cost structures are also analyzed. This report also states import/export consumption, supply and demand Figures, cost, price, revenue, and gross margins. For each manufacturer covered, this report analyzes their Testosterone Booster manufacturing sites, capacity, production, ex-factory price, and revenue and market share in the global market. This helps in the efficient planning and execution of supply chain management as it drastically affects the overall operations of any business. Thus, a market research report can be called a comprehensive guide that helps in better marketing and management of businesses.

Global Testosterone Booster Market report provides the latest forecast market data, industry trends, and technological innovations. The in-depth view of Global Testosterone Booster Market industry on the basis of market size, market growth, opportunities, and development plans offered by the report analysis. The forecast information, SWOT analysis, and feasibility study are the energetic aspects studied in this report. Along with that PESTEL analysis is also considered to be another major aspect of the market study. Another important aspect of every market research report is the study of the key players or manufacturers driving the market forward. This study can benefit investors and business owners in many ways. In order to make business predictions and fetch good results, business models, strategies, growth, innovations and every information about manufacturers that can help are studied by it.

By regions, this report splits the global market into several key regions, with sales, revenue, price and gross margin market share of top players in these regions, from 2020 to 2026 (forecast), likeAmericas(United States, Canada, Mexico, Brazil)APAC(China, Japan, Korea, Southeast Asia, India, Australia),Europe(Germany, France, UK, Italy, Russia, Spain),Middle East & Africa(Egypt, South Africa, Israel, Turkey,GCC Countries)

Global Testosterone Booster Market, By Typeby Component, D Aspartic Acid, Vitamin D3, Other, by Source, Mucuna Pruriens, Ginseng, Oyster Extract, Fenugreek, Stinging Nettle

Global Testosterone Booster Market, By ApplicationsTeenagers, Adults

Key highlights of the global Testosterone Booster market for the forecast years 2020-2026:* CAGR of the market during the forecast period 2020-2025* Detailed information on factors that will accelerate the growth of the Testosterone Booster market during the next five years* Precise estimation of the global Testosterone Booster market size and its contribution to the parent market* Accurate predictions on upcoming trends and changes in consumer behavior* The growth of the Testosterone Booster industry across the Americas, APAC, and EMEA* A thorough analysis of the markets competitive landscape and detailed information on several vendors* Comprehensive details on factors that will challenge the growth of Testosterone Booster providers

From the Testosterone Booster market research reports, the following points are available with detailed study at every point:Production Analysis Initiation of this Testosterone Booster is analyzed based on top countries, types, and applications. Here, the report is expected to extensively focus on the price analysis of varied Testosterone Booster market key players.

Profit and Sales Evaluation Both earnings and sales are verified for various components of this international Testosterone Booster market. The reports focus on the price that plays a vital role in sales development for several regions.

Segments and Advantages In continuation of using earnings, this report studies the design and ingestion of its Testosterone Booster market. This report also highlights the difference between usage and supply, export, and import data.

Competition In this section, many global Testosterone Booster industry-top players have been studied based on their company profile, product portfolio, ability, price, cost, and revenue.

Other Analysis Besides the aforementioned information, demand, and supply scrutiny to the Testosterone Booster economy, contact information from leading producers, suppliers, and major consumers, can also be procured from the report.

The report evaluates the growth rate and the Market value based on Market dynamics, growth inducing factors. Complete knowledge is based on the latest industry news, opportunities, and trends. The report contains a comprehensive Market analysis and vendor landscape in addition to a SWOT analysis of the key vendors.

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In conclusion, The key market segments along with its subtypes are provided in the report. This report especially focuses on the dynamic view of the market, which can help to manage the outline of the industries. Several analysis tools and standard procedures help to demonstrate the role of different domains in the market. The study estimates the factors that are boosting the development of Testosterone Booster companies.

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Global Testosterone Booster Market Growth Projections and Forecast to 2026 | Testofuel, GNC, TestoTEK, Prime Male, TEK Naturals - Skyline Gazette


Mar 30

What The Hell Is Period Beauty And Why Is It So 2020? – Sporteluxe

Feminine care is much less taboo than it was just a short time ago, as our world is embracing the natural and beautiful thing that is the menstrual cycle. Many brands like Cora and Raelare taking back what it means to be a woman. Even skincare is taking note, as period beauty has recently come into the spotlight, with cosmetics brands formulating products to address hormonal changes and skin conditions that occur during that time of the month.Why is vagina is such a dirty word? Companies and women are trying to change that to make it the new norm.

This new movement is empowering women, their hormones, and the products that are purposely (and rightfully so) glamourizing the period. Read all about why you should be changing your skincare during this time and comb through some of our favorite products below!

According to Skin Inc., its no surprise that during the hormonal fluctuations of a womans cycle, the skin experiences some changes. The concept behind period beauty comes with the idea that skin is continuing to change throughout a womans 28-day cycle, so her skincare should change as well. A womens skin changes before, during and after their period can be different from the next. While some women experience a rise in acne, others may only find that their skin tends to be on the oilier side during their period. This trend comes off an even bigger trend of cyclical living, where women are encouraged to embrace their hormonal fluctuations during their cycle and switch up how they live their life based on it.

While no studies have been done on this matter, dermatologist Anjoli Mahto, M.D., did explain that there is a science to back this up. She stated that the second half of your cycle, you do tend to be quite a progesterone and testosterone-heavy, and thats why a lot of people find their skin can get a bit oilier after ovulation and more spot-prone in the run-up to their period.

Brands like Rael have even made entire guides to period beauty, targeting the days before you even begin your menstrual cycle. According to Rael, At least a week before your cycle begins, your estrogen levels begin to decrease while your progesterone and testosterone levels increase. This causes increased oil production and clogged pores, making them appear larger. Hormonal acne will typically occur on your chin and jawline, though breakouts can occur anywhere on your face. Along with your skin being the most sensitive, low levels of estrogen can leave your skin looking blotchy so that by day five your skin becomes dull, dry, and flaky.

You can read more about exactly what to do before, during, and after your period here.

Raels Tips for Treatment

Image: Get Rael

This will give you that Week 2 skin. It is an everyday dream. Raels Complete Care Kit is your skincare dream team, keeping your skin clean, balanced, and moisturized to show off a perpetual Week 2 Glow. Shop here.

Image: Cora

Designed to be the most comfortable andsimple-to-use cup, the Cora Cup is made of premium, medical-grade silicone and is free of BPA and other toxic chemicals. Shop here.

Image: Knours

Thanks to higher levels of testosterone, 7-14 days prior to Aunt Flo, our skin gets oily and our pores are clogged. Let this mask do its magic by hydrating and soothing your skin all while 4 organic aroma oils help you relax and stay calm through this crisis. Apply a drop of the lightweight soothing Skin Meditation Gel Cream to your face morning and night or midday to keep your temperamental skin under control. Shop here.

Image: Lola

Is she ready for her first period? Are you? This set comes with 10padswith wings (5 regular, 5 heavy), 12 ultra-thinliners,10 compact plastic applicators, and more. Shop here.

While youre here, check out what to eat (and do) to stop fluid retention in the body.

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What The Hell Is Period Beauty And Why Is It So 2020? - Sporteluxe


Mar 27

Testosterone Replacement Therapy Market: Rise in Geriatric Population with High Risk of Testosterone Deficiency Boost Market Growth – BioSpace

Transparency Market Research (TMR)has published a new report titled, Testosterone Replacement Therapy Market - Global Industry Analysis, Size, Share, Growth, Trends, and Forecast, 20192027.According to the report, the globalTestosterone Replacement Therapy marketwas valued atUS$ 1,613.7 Mnin2018and is projected to expand at a CAGR of4.4%from2019to2027.

Overview

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Growing Awareness about Testosterone Replacement Therapy to Drive Market

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North America to Dominate Global Market

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Competitive Landscape

About Us

Transparency Market Research is a next-generation market intelligence provider, offering fact-based solutions to business leaders, consultants, and strategy professionals.

Our reports are single-point solutions for businesses to grow, evolve, and mature. Our real-time data collection methods along with ability to track more than one million high growth niche products are aligned with your aims. The detailed and proprietary statistical models used by our analysts offer insights for making right decision in the shortest span of time. For organizations that require specific but comprehensive information we offer customized solutions through adhoc reports. These requests are delivered with the perfect combination of right sense of fact-oriented problem solving methodologies and leveraging existing data repositories.

TMR believes that unison of solutions for clients-specific problems with right methodology of research is the key to help enterprises reach right decision.

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Testosterone Replacement Therapy Market: Rise in Geriatric Population with High Risk of Testosterone Deficiency Boost Market Growth - BioSpace



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