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Aytu BioScience Expands Its Distribution Rights for Coronavirus 2019 (COVID-19) Point-of-Care Rapid Test to Canada and Mexico – Yahoo Finance
Company Expects to Seek Regulatory Clearance Under Health Canada and COFEPRIS Expedited Clearance Procedures
ENGLEWOOD, CO / ACCESSWIRE / March 19, 2020 / Aytu BioScience, Inc. (AYTU), a specialty pharmaceutical company focused on commercializing novel products that address significant patient needs announced today that it extended its distribution right to commercialize the clinically validated and commercially used coronavirus 2019 (COVID-19) IgG/IgM Rapid Test. The test has been licensed from L.B. Resources, Limited (a Hong Kong Corporation). The COVID-19 IgG/IgM Rapid Test is intended for professional use and delivers clinical results between 2 and 10 minutes at the point-of-care. This amendment expands Aytu's commercial rights and grants Aytu the right to distribute and commercialize the COVID-19 test in North America, specifically including the United States, Canada and Mexico.
The Company expects to pursue expedited regulatory clearance of the product with Health Canada and COFEPRIS (Comisin Federal para la Proteccin contra Riesgos Sanitarios), the regulatory agencies in Canada and Mexico, respectively.
Josh Disbrow, Chief Executive Officer of Aytu BioScience, commented, "We have to be progressive in doing our part in combatting the spread of the COVID-19 virus. We need to ensure that screening is available across North America and providing broad access to screening tests has to be among our highest priorities as we collectively fight the coronavirus outbreak. With COVID-19 now designated as a global pandemic, we believe we should expand our efforts to assist healthcare providers with faster point-of-care detection."
The COVID-19 IgG/IgM Rapid Test is a solid phase immunochromatographic assay used in the rapid, qualitative and differential detection of IgG and IgM antibodies to the 2019 Novel Coronavirus in human whole blood, serum or plasma. This point-of-care test has been validated in a 113 patient clinical trial and is CE marked.
About Aytu BioScience, Inc.
Aytu BioScience is a commercial-stage specialty pharmaceutical company focused on commercializing novel products that address significant patient needs. The company currently markets a portfolio of prescription products addressing large primary care and pediatric markets. The primary care portfolio includes (i) Natesto, the only FDA-approved nasal formulation of testosterone for men with hypogonadism (low testosterone, or "Low T"), (ii) ZolpiMist, the only FDA-approved oral spray prescription sleep aid, and (iii) Tuzistra XR, the only FDA-approved 12-hour codeine-based antitussive syrup. The pediatric portfolio includes (i) AcipHex Sprinkle, a granule formulation of rabeprazole sodium, a commonly prescribed proton pump inhibitor; (ii) Cefaclor, a second-generation cephalosporin antibiotic suspension; (iii) Karbinal ER, an extended-release carbinoxamine (antihistamine) suspension indicated to treat numerous allergic conditions; and (iv) Poly-Vi-Flor and Tri-Vi-Flor, two complementary prescription fluoride-based supplement product lines containing combinations of fluoride and vitamins in various for infants and children with fluoride deficiency. Aytu recently acquired exclusive U.S. distribution rights to the COVID-19 IgG/IgM Rapid Test. This coronavirus test is a solid phase immunochromatographic assay used in the rapid, qualitative and differential detection of IgG and IgM antibodies to the 2019 Novel Coronavirus in human whole blood, serum or plasma. This point-of-care test has been validated in a 113 patient clinical trial and has received CE marking.
Aytu recently acquired Innovus Pharmaceuticals, a specialty pharmaceutical company commercializing, licensing and developing safe and effective consumer healthcare products designed to improve men's and women's health and vitality. Innovus commercializes over thirty-five consumer health products competing in large healthcare categories including diabetes, men's health, sexual wellness and respiratory health. The Innovus product portfolio is commercialized through direct-to-consumer marketing channels utilizing the company's proprietary Beyond Human marketing and sales platform.
Aytu's strategy is to continue building its portfolio of revenue-generating products, leveraging its focused commercial team and expertise to build leading brands within large therapeutic markets. For more information visit aytubio.com and visit innovuspharma.com to learn about the company's consumer healthcare products.
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Forward-Looking Statement
This press release includes forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, or the Exchange Act. All statements other than statements of historical facts contained in this presentation, are forward-looking statements. Forward-looking statements are generally written in the future tense and/or are preceded by words such as ''may,'' ''will,'' ''should,'' ''forecast,'' ''could,'' ''expect,'' ''suggest,'' ''believe,'' ''estimate,'' ''continue,'' ''anticipate,'' ''intend,'' ''plan,'' or similar words, or the negatives of such terms or other variations on such terms or comparable terminology. These statements are just predictions and are subject to risks and uncertainties that could cause the actual events or results to differ materially. These risks and uncertainties include, among others: market and other conditions, the completion of the registered direct offering, the satisfaction of customary closing conditions related to the registered direct offering and the intended use of net proceeds from the registered direct offering, the regulatory and commercial risks associated with introducing the COVID-19 Rapid Test, effects of the business combination of Aytu and the Commercial Portfolio and the recently completed merger ("Merger") with Innovus Pharmaceuticals, including the combined company's future financial condition, results of operations, strategy and plans, the ability of the combined company to realize anticipated synergies in the timeframe expected or at all, changes in capital markets and the ability of the combined company to finance operations in the manner expected, the diversion of management time on Merger-related issues and integration of the Commercial Portfolio, the ultimate timing, outcome and results of integrating the operations the Commercial Portfolio and Innovus with Aytu's existing operations, risks relating to gaining market acceptance of our products, obtaining or maintaining reimbursement by third-party payors for our prescription products, the potential future commercialization of our product candidates, the anticipated start dates, durations and completion dates, as well as the potential future results, of our ongoing and future clinical trials, the anticipated designs of our future clinical trials, anticipated future regulatory submissions and events, our anticipated future cash position and future events under our current and potential future collaboration. We also refer you to the risks described in ''Risk Factors'' in Part I, Item 1A of the company's Annual Report on Form 10-K and in the other reports and documents we file with the Securities and Exchange Commission from time to time.
Contact for Media and Investors:
James CarbonaraHayden IR(646) 755-7412james@haydenir.com
SOURCE: Aytu BioScience, Inc.
View source version on accesswire.com: https://www.accesswire.com/581543/Aytu-BioScience-Expands-Its-Distribution-Rights-for-Coronavirus-2019-COVID-19-Point-of-Care-Rapid-Test-to-Canada-and-Mexico
Stream On: At home and abroad, after 9/11 – The Outer Banks Voice
By Peter Hummers on March 19, 2020
The attacks on America on Sept. 11, 2001 changed everything, including TV drama. From a New York City fire station to Washington, Yemen and Venezuela, these two television dramas arose to deal with their aftermath and responses.
RESCUE ME (Hulu; on-demand on several other platforms) 2004-2011 [TVMA]
This 2004 FX series focuses on New York firefighter Tommy Gavins (Denis Leary) family and the men of his firehouse. Tommy is an impatient, self-loathing, hypocritical, manipulative relapsed alcoholic who suffers with severe survivor guilt and post-traumatic stress as a result of 9/11. He blames himself for his firefighter cousins death in the twin towers, while entering into an affair with his cousins widow.
Tommys cousin, indeed, a small group of the dead that he blames himself for, follow him around, firefighters and chidren, with whom he seems to be in onging communication.
A comedy-drama, Rescue Me is both personal and blunt, while the comedy ranges from guy stuff (the station house is teeming with testosterone) to the blackest situations that find laughs even in death and devastation among the major cast. Recurring guests on this popular show included Maura Tierney, Artie Lange, Susan Sarandon, Marisa Tomei and Michael J. Fox.
The series premiere garnered Denis Leary and Peter Tolan (Analyze This) an Emmy nomination for Outstanding Writing in a Drama Series. Tolan also received an Emmy nomination for Outstanding Directing in a Drama Series. Leary received another Emmy nomination the next year, this time for Outstanding Lead Actor in a Drama Series. Heres a trailer for the Season 1 DVD set.
TOM CLANCYS JACK RYAN (Prime Video; Season 1 on-demand on several other platforms) 2018 [TVMA]
Carlton Cuse (Bates Motel) and writer Graham Roland (Lost, Fringe) are the latest to take on Tom Clancys creation Dr. Jack Ryan, the CIA analyst who first appeared in the 1984 novel The Hunt for Red October and has since, like Sherlock Holmes and Norman Bates, transcended time. Ryan has been portrayed by Alec Baldwin, Harrison Ford, Ben Affleck and Chris Pine; in this 2018 Amazon Prime original series, John Krasinski (The Office) dons the mantle.
Here, Ryan is younger than in the Harrison Ford films and not married, although this series takes place in the present. The first season follows him as he is wrenched from the security of his desk job into the field after discovering a string of dubious bank transfers, which are being carried out by a rising Islamic extremist named Suleiman.
Ryans commanding officer at the Terror, Finance, and Arms Division (T-FAD) of the CIA, James Greer (Wendell Pierce, The Wire), snatches Ryan from a party to Yemen to interrogate the man assumed to be responsible and his bodyguard, when the base where they are is attacked by rebels.
Director and Executive Producer Daniel Sackheim has said, What was so great about the Harrison Ford movies was that they were about an everyman hero. He was a guy who wasnt a superhero. He was heroic, but he was vulnerable. He wasnt afraid to be scared. He was a regular man and a hero (IndieWire), and Krasinski, best known as office drone Jim Halpert, fits the part like a glove.
The terrorist Suleiman is given personal motives that transcend politics and so is relatable to any audience. The plots are intriguing and solid and the action set-pieces are flashy while apparently realistic. The Suleiman plot wraps up with the first season, and the second season opens in Venezuela. Heres a trailer for the first season.
Next time, well go back in the day with young Clark Kent and Bruce Wayne. Email me and follow Stream On OBX on Twitter.
Click here for more Stream On: What to watch on TV columns by Peter Hummers.
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Stream On: At home and abroad, after 9/11 - The Outer Banks Voice
Testosterone Replacement Therapy Market 2020 Industry Analysis, Size, Share, Strategies, Demand Analysis and Projected huge Growth by 2026 – Feed…
This Testosterone replacement therapy market intelligence study curates an exhaustive database of industrial essentials for formulating favorable strategies. A thorough investigation of the value chain and the distribution channel is provided in this study by business professionals. The Market study offers detailed information pertaining to the extent and application of the market, which helps better understand the global sector. This report on the Global Market discusses several growth prospects, including the industry sectors, current trends, up-to-date outlines, driving factors, and hurdles, overall offering market projections for the coming years.
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In market segmentation by types of testosterone replacement therapies, the report covers
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Regional Outlook (Revenue in USD Million; 20162026)
Key highlights of the Testosterone Replacement Therapy market:
The report is distributed over 15 Chapters to display the analysis of the global Testosterone Replacement Therapy market.
Chapter 1 covers the Blow-Fill-Seal (BFS) technology product Introduction, product scope, market overview, market opportunities, market risk, market driving force;
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Chapter 3 displays the competitive nature of the market by discussing the competition among the top manufacturers. It dissects the market using sales, revenue and market share data for 2016 and 2017;
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Browse Table of Contents with Facts and Figures of Testosterone Replacement Therapy Market Report at: https://www.reportsanddata.com/report-detail/global-testosterone-replacement-therapy-market-by-manufacturers-countries-type-and-application-forecast-to-2022
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Woman who tried to be male accuses doctor of lying about transition impact – Lifesite
BELGIUM, March 13, 2020 (LifeSiteNews) A 21-year-old woman from Belgium who portrayed herself as a male, then reverted to presenting herself according to hertrue sex is speaking out about the deception of the doctor who encouraged her to go through with hormone drugs and mutilating surgeryand the lack of countervailing voices that could have spared her the experience.
This week, the BBC published an interview with Ellie and her 24-year-old paramour Nele, who is also a former trans man. Both subjected themselves to testosterone as well as double mastectomies.
I realised I was doing a lot of boy things, and some people werent fine with that especially other kids, Ellie recalls of her childhood. In her teens, she came out as a lesbianand decided, I just didnt want to be a woman. I wanted to be neutral and do whatever I wanted.
She began to seek out male hormones at age 16 after seeing YouTube videos on the subject. The first doctor she and her parents consulted suggested waiting until she was older, so she found a second one who told her what she wanted to hear. A year later, she had her breasts removed.
He told my parents that all the effects [of hormones] were reversible which is the biggest lie, Ellie recalls. I had done my research, and I knew that this doctor could not be trusted. But I was just so happy that he said that, because then my parents were OK with it.
Her father Eric recalls having reservationsbut feeling reassured by the doctor that this was for the best. I wouldve liked to have met someone to give me the words and find arguments to make her wait and think about it longer, but there was no-one, he admits.
As a university student in Germany, Ellie initially enjoyed living as and passing for a man, but eventually, she started to feel like I had to hide so many aspects of my life, and not talk about my childhood as a girl. I didnt feel comfortable being seen as a cis man, and I started to feel like I didnt fit in anywhere.
These issues made dating a challenge, but eventually she met Nele, and the two bonded over their shared issues. Nele too had grown up uncomfortable with her sex, had taken transgender hormones, and with Ellies support had her own double mastectomy.
Yet personal and ideological factors both continued to cast doubts on their male identities. The ongoing debate between transgender activists and traditional feminists had Ellie questioning if she was truly transgendered or if her change was just a way I found to go through life, while she and Nele were both diagnosed with vaginal atrophy, a side-effect of testosterone.
Isnt it worth trying to go natural for a bit, and just see how it goes? Nele thought, and Ellie agreed.
Today, the two maintain the website Post-Trans.com, a space for female detransitioners and desisters to share their journeys.
Detransitioning for me means to stop denying the female experience I have, Ellie writes. Detransitioning for me means taking agency over my dysphoria. Detransitioning for me means discovering the body I started altering since the age of 16 and finally working on accepting it exactly the way it is. Detransitioning for me does not mean trying to go back to my insecure 16-year-old self, but to move forward and become the strong female individual I want to be.
Nele says that despite her experiences and ultimate decision to reverse it, she doesnt regret her initial transition. She credits transition as the only alternative to suicide she saw at the timebut acknowledges that it also brought me to a place of reflection on why I really transitioned, which eventually ended with her resolving to face the bad image of women that society taught me and embrace a new and stronger one.
A range of medical literature suggests that exposing gender-confused children to transition treatment is harmful in the long run, in no small part because fixating on gender affirmation tends to distract from exploring other issues that may be at the root of a patients mental or emotional unrest.
In 2017, the University of Cambridges Stonewall report found that 96 percent of trans students in Scotland attempted self-harm through actions such as cutting themselves, and 40 percent attempted suicide. Forty percent in the United States have attempted suicide, as well, according to a 2016 survey from the National Center for Transgender Equality (NCTE). According to a 2011 study out of Sweden, trans people remain 19 times more likely to commit suicide than the general population, even after surgery to reconstruct their bodies.
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Woman who tried to be male accuses doctor of lying about transition impact - Lifesite
8 Proven Ways to Increase Testosterone Levels Naturally
Testosterone is the main male sex hormone, but females also have small amounts of it.
It is a steroid hormone, produced in mens testicles and womens ovaries (1).
The adrenal glands also produce small amounts.
During puberty in boys, testosterone is one of the main drivers of physical changes like increased muscle, deeper voice and hair growth.
However, having optimal levels is also important throughout adulthood and even during old age.
In adults, healthy levels are important for general health, disease risk, body composition, sexual function and just about everything else (1, 2, 3, 4, 5, 6, 7).
Additionally, increasing your testosterone levels can cause rapid gains in muscle mass and vitality in only a matter of weeks (8, 9, 10).
Interestingly, it also plays an important role in female health and sexual well-being (11, 12, 13).
The research is pretty conclusive: both genders should ensure they have healthy levels of testosterone, especially as they age (13, 14).
Here are 8 evidence-based ways to increase testosterone levels naturally.
Exercise is one of the most effective ways to prevent many lifestyle-related diseases. Interestingly, it can also boost your testosterone.
A large review study found that people who exercised regularly had higher testosterone levels. In the elderly, exercise increases testosterone levels, fitness and reaction time (15, 16).
New research in obese men suggests that increased physical activity was even more beneficial than a weight loss diet for increasing testosterone levels (17).
Resistance training, such as weight lifting, is the best type of exercise to boost testosterone in both the short- and long-term (18, 19).
High-intensity interval training (HIIT) can also be very effective, although all types of exercise should work to some extent (18, 19, 20, 21, 22).
Taking caffeine and creatine monohydrate as supplements may further boost your levels when combined with a training program (23, 24).
What you eat has a major impact on testosterone as well as other hormone levels (25).
Therefore, you must pay attention to your long-term calorie intake and diet strategy.
Constant dieting or overeating may disrupt your testosterone levels (26, 27, 28, 29, 30).
Eating enough protein can help maintain healthy levels and aid in fat loss, which is also associated with your testosterone (28, 31, 32).
Carb intake also plays a role, with research showing carbs can help optimize testosterone levels during resistance training (22, 33).
However, research demonstrates that sufficient healthy fats are also beneficial for testosterone and health (25, 34, 35, 36, 37).
A diet based mainly on whole foods is best, with a healthy balance of fat, protein and carbs. This can optimize both hormone levels and long-term health.
Research is always highlighting the dangers of long-term stress, which can elevate levels of the hormone cortisol (38, 39, 40).
Unnatural elevations in cortisol can quickly reduce testosterone. These hormones work in a seesaw-like manner: as one goes up, the other comes down (40, 41, 42).
Stress and high cortisol can also increase food intake, weight gain and the storage of harmful body fat around your organs. In turn, these changes may negatively impact your testosterone levels (43, 44, 45).
For both optimal health and hormone levels, you should try to reduce repetitive stressful situations in your life.
Focus on a diet based on whole foods, regular exercise, good sleep, laughter and a balanced lifestyle, all of which can reduce stress and improve your health and testosterone levels (46, 47, 48, 49, 50).
Vitamin D is quickly becoming one of the worlds most popular vitamins.
Research has shown that it has various health benefits, and may also work as a natural testosterone booster (51, 52, 53, 54, 55).
Despite its importance, nearly half of the US population is deficient in vitamin D, and an even higher percentage has sub-optimal levels (56, 57).
A 12-month study found that supplementing with around 3,000 IU of vitamin D3 per day increased testosterone levels by around 25% (54).
In the elderly, vitamin D and calcium also optimized testosterone levels, which led to a reduced risk of falling (58).
To boost testosterone and reap the other benefits of vitamin D, try to get regular exposure to sunlight or take around 3,000 IU of a vitamin D3 supplement daily.
If you'd like to try supplements, Amazon has a good selection available.
More information on vitamin D here: Vitamin D 101 A Detailed Beginners Guide.
Although the benefits of multivitamins are hotly debated, specific vitamins and minerals may be beneficial (59).
In one study, zinc and vitamin B supplements increased sperm quality by 74%. Zinc also boosts testosterone in athletes and those who are deficient in zinc (60, 61, 62).
Other studies also suggest vitamins A, C and E can play a role in your sex hormone and testosterone levels, although more research is needed (25, 63, 64, 65).
Out of all the vitamins and minerals available, the research on testosterone shows vitamin D and zinc supplements may be best (54, 66, 67).
Getting good sleep is just as important for your health as diet and exercise (68, 69, 70, 71, 72, 73).
It may also have major effects on your testosterone levels.
The ideal amount of sleep varies from person to person, but one study found that sleeping only 5 hours per night was linked to a 15% reduction in testosterone levels (73).
One long-term study observed that those who slept only four hours per night had borderline deficient levels (46).
Other long-term studies support this. One study calculated that for every additional hour of sleep you get, testosterone levels rise 15% higher, on average (74, 75).
Although some people seem to do fine with less sleep, research suggests around 710 hours of sleep per night is best for long-term health and your testosterone.
Only a few natural testosterone boosters are supported by scientific studies.
The herb with the most research behind it is called ashwagandha.
One study tested the effects of this herb on infertile men and found a 17% increase in testosterone levels and a 167% increase in sperm count (76).
In healthy men, ashwagandha increased levels by 15%. Another study found it lowered cortisol by around 25%, which may also aid testosterone (77, 78).
Ginger extract may also boost your levels. It is a delicious herb that also provides various other health benefits (79, 80, 81, 82, 83).
Most of the research on ginger has been done in animals. However, one study in infertile humans found that ginger can boost testosterone levels by 17% and increase levels of other key sex hormones (80, 84).
Other popular herbs that are supported by some studies in both animals and humans include horny goat weed, Mucuna pruriens, shilajit and tongkat ali.
Yet its important to note that most of the positive research has been conducted in mice or infertile humans with low testosterone levels.
If you have healthy testosterone function and normal levels, it is unclear whether you will benefit much from these supplements.
There are several other factors that may affect your hormone levels.
A healthy sex life plays an important role in regulating your sex hormone and testosterone levels (85, 86).
High exposure to estrogen-like chemicals may also affect your levels, so try to minimize daily exposure to BPA, parabens and other chemicals found in some types of plastic (86, 87, 88, 89).
Its probably no surprise that excess alcohol or drug use, whether its medical or recreational, can also decrease testosterone levels (90, 91, 92, 93, 94, 95).
In contrast, laughter, happiness and success may help boost your health and testosterone levels so make sure theyre a part of your daily life (96, 97, 98, 99).
From the age of 2530, a mans testosterone levels naturally start to decline.
This is a problem because strong research shows a link between low testosterone and obesity, increased disease risk and premature death.
Healthy testosterone levels are also important for women, along with other key hormones such as estrogen and progesterone.
Therefore, everyone should take the necessary lifestyle steps to optimize testosterone levels. You will improve your health and body at the same time.
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UK teen girl wanted to be male; got breasts removed, took testosterone. Now 23, she says doctors should have ‘challenged’ her decision and is suing….
Keira Bell of the United Kingdom told BBC News she was a tomboy as a child and the sense she needed to transition to a male occurred gradually as she read about it online.
Bell soon sought the assistance of medicine at age 16, went to a clinic, and after three appointments lasting an hour each she was prescribed puberty blockers, the outlet said.
A year later Bell told the BBC she was prescribed the male hormone testosterone, which developed male characteristics like facial hair and a deep voice and three years ago, she got her breasts removed.
"Initially I felt very relieved and happy about things," Bell told the outlet. "But I think as the years go on you start to feel less and less enthusiastic or even happy about things."
In the end, she decided to stop taking cross-sex hormones last year. Now at 23, Bell noted to the BBC that she accepts her sex as a female but she's also angry about what happened to her.
"I was allowed to run with this idea that I had, almost like a fantasy, as a teenager," Bell told the outlet, adding that "it has affected me in the long run as an adult. I'm very young. I've only just stepped into adulthood, and I have to deal with this kind of burden or radical difference in comparison to others at least."
More than that, she told the BBC that others should have pushed back against her decision.
"I should have been challenged on the proposals or the claims that I was making for myself," Bell told the outlet. "And I think that would have made a big difference as well. If I was just challenged on the things I was saying."
Now Bell is taking legal action against the National Health Service gender clinic, and a judge cleared the way for a full hearing of the case against the Tavistock and Portman NHS Trust, the BBC said.
Lawyers will argue that children cannot give informed consent to treatment delaying puberty or helping them to transition, the outlet added.
The clinic based in Hampstead, northwest London which runs the UK's only gender-identity development service told the BBC it welcomed an examination of the evidence. But former clinic staff at the clinic have said teens who want to change their genders are given puberty blockers without adequate assessment or psychological work, the outlet added.
Bell herself admitted to the BBC that when she went to clinic years ago, she would say "it was saving me from suicidal ideation and depression in general and at the time I felt it relieved all those mental health issues I was feeling, alongside gender dysphoria."
In addition, Bell told the outlet that if she had felt more accepted by society as a teen, she might not have wanted to change her gender though she added she wouldn't have wanted to listen to challengers of her transgender desires.
"I feel I could say anything to my 16-year-old self, and I might not necessarily listen at that time," Bell added to the BBC. "And that's the point of this case, when you are that young you don't really want to listen. So I think it's up to these institutions, like the Tavistock, to step in and make children reconsider what they are saying, because it is a life-altering path."
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UK teen girl wanted to be male; got breasts removed, took testosterone. Now 23, she says doctors should have 'challenged' her decision and is suing....
The Science Behind Why Winning Makes You Want To Keep Playing Games | Invision Game Community – Invision Game Community
So youve just beaten the other team or won against someone in a 1v1 on your favourite game and you feel great. Winning is actually one of the best feelings that we know. This is because when we win, our brains receive a boost of testosterone, dopamine and endorphins. Whats more is that dopamine and endorphins often trigger the release of adrenaline, leading to our winning feeling a pretty dizzying mixture of excitement, euphoria and pride that can be addictive. You can also get this rush from a range of other successes, making you want to repeat your victory repeatedly.
The Winner Effect
In biology, the winner effect is used to describe how an animal, whether it be a mouse or a lion, is far more likely to win against stronger opponents after having won against weaker opponents. This is in part due to the boost of testosterone and dopamine that comes with each win, which researchers have discovered to have not only short-term effects but also long-term effects on the animal. In the long run, these testosterone and dopamine hits make the animal more confident, motivated and even smarter as they learn from their victories. Researchers have also uncovered that the winner effect not only applies to animals, but also to humans. The winner effect can exacerbate our addiction to winning because it makes it a more realistic prospect.
This infographic courtesy of bestnewbingosites.co.uk illustrates the varying effects that winning can have both on our brains and our bodies.
Dopamine and Motivation
The dopamine hit that come with a win can be difficult to ignore. Your body treats dopamine as a reward and remembers the feelings of victory. It then will motivate you to try win again, which is possibly why it is hard to stop playing games sometimes. Whether that means completing a more challenging round of a video game or to spend more time in training. This heightened level of motivation means makes you a lot more likely to win, however, you shouldnt obsess if things dont work out for you the very first time around.
Testosterone and Competitiveness
Testosterone is heightened after a win, and thus some effects are a boost in sense of power, dominance and competitiveness. This feeling will drive you to compete again and again to chase that feeling when you defeated a mega boss or your opponent in a 1v1. If you lose the feeling is awful as your body releases chemicals as highlighted in the infographic that punishes you. Testosterone levels actually have been found to drop after a loss.
Overall, the effects of winning in video games create long term effects on your body and brain. Winning in anything not only games will change your brain chemistry to try to win again and thus this is where gaming can get addictive.
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Even the playing field: a look at how House Bill 500 affects the transgender community – Argonaut
Idahos House of Representatives passed the Fairness in Womens Sports Act, HB 500, a bill which would ban transgender women from participating in womens high school and college sports in the state. The bills text conflicts with preexisting NCAA and Idaho High School Activities Association womens athletics policies and if passed will overrule those regulations.
According to the bills statement of purpose, (transgender women) will not be allowed to participate on girls or womens teams, as defined by their inherent differences that are physiological, chromosomal, and hormonal.
The bill conflicts with the existing bylaws related to hormonal treatment and screening of transgender student-athletes in the NCAA Handbook on Transgender Student-Athlete Participation.
Carson Poertner, a former NCAA athlete, UI student, and transgender man, said HB 500 disregards NCAA policy.
Next month, the NCAA will have had an inclusion policy specifically for transgender student-athletes in place for a decade. Its very frustrating, because there are already good, inclusive policies to have an even and fair playing field in place nationally, Poertner said. All of that information, research and evidence is being thrown away for somebodys personal feelings, essentially.
According to the NCAA, a transgender woman student-athlete being treated with testosterone suppression medication must complete one calendar year of that treatment before competing on a womens team. HB 500 disputes this calendar year minimum policy, stating, The benefits that natural testosterone provides to (transgender women) athletes is not diminished through the use of puberty blockers and cross-sex hormones.
ICYM: The state doesnt care about us: transgender students and community members speak up about recent house bills
On Tuesday HB 500 was amended to say if a school wanted to check a players eligibility, they would not have to go through all three steps of the screening but instead just one.
The three ways are as follows:The health care provider may verifythe students biological sex as part ofa routine sports physical examinationrelying only on one (1) or more of thefollowing: the students reproductiveanatomy, genetic makeup or normalendogenously produced testosteronelevels.
The bills amendment also removesall references to the NCAA.
One of the three steps of player eligibility screening outlined in the bill calls for a physicians statement regarding physical examinations of internal and external physical anatomy of athletes in question. Poertner said this step of the screening method is unfair and has the potential to traumatize student-athletes, especially those who do not feel comfortable with the bills proposed genital identification binaries.
Biological sex can be determined by chromosome makeup, hormones or genitalia. It could be a mix of all those three its not black and white. For example, we have a population who are intersex and dont fit into this binary, Poertner said. So, now youre going to other them, push them aside and traumatize them by making them get undressed in front of a physician, and tell them their body is not normal. That they are not allowed to be a kid, to play sports.
The Idaho High School Activities Associations (IHSAA) Transgender Student Participation guidelines mimic that of the NCAA in employing the same calendar year-minimum policy for hormone suppression treatment by transgender women prior to being eligible to participate in womens sports.
Greg Bailey, Moscow School District Superintendent, said he was on the IHSAA Board from 2009 to 2015. During that time the states current policy for transgender high school athletes was drafted. Bailey said the issues of participation in sports by transgender athletes have already been addressed by the IHSAA, and that he is confused as to why one legislator is trying to make an issue out of something that has never caused a problem in the state.
One of the things we are concernedabout is how this will impact not onlyhigh schools, but colleges that are inthe state of Idaho if we have a rulingthat is opposite of NCAA, Bailey said.Legislators should consider morepertinent issues that are at hand thansomething like this, that appears to bejust one legislators concern.
Julia Keleher, UI LGBTQAdirector, said the bill does notacknowledge the big picture whenit comes to athletics and life fortransgender people in general
Its this idea that trans girls are inherently advantaged in sports because they have male bodies physical bodies and (the bill) is looking at seeing people for their bodies and their genitals and not for their identities, Keleher said. The reality is that when we look at trans women and trans people in general, theyre more likely to experience discrimination, harassment, assaults, murder.
HB 500 was introduced by Rep.Barbara Erhardt (R-Idaho Falls) andpassed through the House 52-17. Thebill then moved to the Senate and iscurrently being amended in the StateAffairs Committee.
Erhardt could not be reached forcomment.
Joe St. Pierre, UI Athletics Communications Director, declined to comment regarding HB 500.
Alex Brizee contributed to this article.
Ellen Dennis can be reached at arg-news@uidaho.edu
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Even the playing field: a look at how House Bill 500 affects the transgender community - Argonaut
Testosterone Replacement Therapy Market Organization Sizes Analysis 2019-2025 – Packaging News 24
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Amputee’s New Hands Adapt to Her Body – Courthouse News Service
NEW DELHI (AFP) When amputee Shreya Siddanagowder was offered new hands, the Indian student didnt hesitate even though they were big, dark and hairy, and once belonged to a man.
Remarkably, not only have her new hands become more slender, they have changed color to match her skin tone, mystifying the doctors who carried out the rare 13-hour transplant.
The donor was a tall man with big spindly fingers, Siddanagowders mother Suma told AFP by phone from their home in Pune in western India.
Siddanagowders life was turned upside down in 2016, when at 18 she was involved in a bus accident that crushed both her arms.
A delay in getting first aid caused both her hands to be amputated below the elbow.
Only 200 successful hand transplants have taken place worldwide including nine in India since the first in the United States in 1999 on a man whose left limb had been blown off by a firework.
The first in India was conducted in 2015 at the Amrita Institute of Medical Science in the southern state of Kerala, where Siddanagowders family took her.
The biggest problem was finding a donor. For cultural reasons, Indian families are often reluctant for the hands of loved ones to be made available after death.
Usually you have to wait for a long time, said Subramania Iyer, a member of a team of doctors who operated on Siddanagowder.
As a result, those seeking a transplant are so desperate that they dont mind if the hands are from a different gender, Iyer said.
The hospital obtained a pair of hands from a man in August 2017. Siddanagowder and her family accepted.
The donor hands were first attached by the bones, before the tendons, blood vessels and skin were painstakingly stitched together.
After the transplant, she had to undergo more than a year of physiotherapy for her body and brain to get used to the new hands and obtain mobility and sensation.
Iyer said that the color of Siddanagowders hands quickly began to show a lot of change, and it is difficult to pinpoint why.
It could be because of MSH a brain-controlled hormone that stimulates melanin production. We are wondering if MSH levels can really influence the skin color, he said.
Melanin is a natural pigment that gives skin, hair and eyes their color.
Dr. Shehla Agarwal, a leading dermatologist in New Delhi, said that the absence of testosterone explained why the hands became less hairy, and that other hormonal changes might explain the change in color.
She also cited other possible factors.
The donor male may have been exposed to more sunlight and physical activity compared to the woman, Agarwal told AFP.
Shreya is loving the transformation she even wrote her recent college exam with her new hands and so are her doctors.
We all feel very happy for her, said Iyer.
The best moment was when she sent me a handwritten note on my birthday. I could not have asked for a better birthday gift.
Agence France-Presse
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Amputee's New Hands Adapt to Her Body - Courthouse News Service