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Nov 19

Testosterone Replacement Therapy Market Report 2019 : Global Analysis and Forecast by 2027 – Eastlake Times

The Testosterone Replacement Therapy Market report is a thorough analysis of the market that offers a detailed assessment of the market situation for the forecast period 2019-2027. The report systematically explains market trends, growth opportunities, challenges, drivers, and other factors impacting the Testosterone Replacement Therapy market. The key focus of the report assists business owners in understanding the market in terms of its segmentation, regional distribution, and influential trends. The report will provide readers a comprehensive analysis of the Testosterone Replacement Therapy market with a broad perspective into the global economy and competitive landscape. The report contains first-hand data of market trends, obtained through rigorous research that can transform the arc of your Business.

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The Testosterone Replacement Therapy report offers the plus points as well as weaknesses of the established market players. It analyses numerous features of the global Testosterone Replacement Therapy market such as demand, drivers, challenges, and options. The report appraises the influence of these aspects on each market region during the estimated time. It presents the value chain analysis together with vendor list and highlights the present market situation between consumer and supplier.

In order to give the users of this report a comprehensive view of the Testosterone Replacement Therapy market, we have included a competitive landscape and an analysis of Porters Five Forces model for the market. The study encompasses a market attractiveness analysis, wherein all the segments are benchmarked based on their market size, growth rate, and general attractiveness.

The years considered to estimate the Insights of Testosterone Replacement Therapy Market are as follows:-

History Year: 2014-2018

Base Year: 2018

Estimated Year: 2019

Forecast Year: 2019 to 2027

Key Highlights of Global Testosterone Replacement Therapy Market Report 2019:

Snaps From the Testosterone Replacement Therapy Report / TOC :

1 Market Overview

1.1 Testosterone Replacement Therapy Introduction

1.2 Market Analysis by Type

1.3 Market Analysis by Applications

1.4 Market Analysis by Regions

North America (USA, Canada and Mexico)

Europe (Germany, France, UK, Russia and Italy)

Asia-Pacific (China, Japan, Korea, India and Southeast Asia)

South America, Middle East and Africa

1.5 Market Dynamics

2 Manufacturers Profiles

3 Global Testosterone Replacement Therapy Market Competition, by Manufacturer

4 Global Testosterone Replacement Therapy Market Analysis by Regions

4.1 Global Testosterone Replacement Therapy Sales, Revenue and Market Share by Regions

(continued)

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10 Global Testosterone Replacement Therapy Market Segment by Type

11 Global Testosterone Replacement Therapy Market Segment by Application

12 Testosterone Replacement Therapy Market Forecast (2019-2027)

13 Sales Channel, Distributors, Traders and Dealers

14 Research Findings and Conclusion

Testosterone Replacement Therapy market will prove as a valuable source of guidance for professional clients like Tier 1, Tier 2, Tier 3 level managers, CEOs, CMOs, as well as interested individual readers across the world. Vendor Landscape provide acts as key development and focus of above professional with common aim to lead the way of Testosterone Replacement Therapy market Worldwide.

If you have any special requirements, please let us know and we will offer you the report as you want.

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Testosterone Replacement Therapy Market Report 2019 : Global Analysis and Forecast by 2027 - Eastlake Times


Nov 19

Watch out for these five men’s health conditions – Daily Herald

A doctors office might not be a guys favorite place to be. According to the Centers for Disease Control and Prevention, men are less likely to visit the doctor than women and thats regardless of age.

Men dont get a pass when it comes to their health. Your health is just as important as the people around you, and it may surprise you to know that there are some health problems unique to men that shouldnt be ignored.

Here are some special health issues that should be good reasons to stick with your regular doctor visits.

Prostate cancer screenings are nobodys favorite pastime, but this tool is essential for catching cancer early. Once you begin to notice symptoms of prostate cancer, it has likely progressed to an advanced stage. Catching this disease before symptoms appear gives you a much better chance of beating it. Along with a physical exam, a Prostate Specific Antigen blood test can help screen for cancer.

As men get older, they might develop an enlarged prostate. This common condition can result in extreme discomfort as urine flow becomes blocked. Some men might feel a frequent need to urinate or have trouble going to the bathroom. Although it is not unusual to experience an enlarged prostate, men do not have to endure these symptoms without relief. An enlarged prostate could get better on its own, or with treatments like medication, therapy or surgery.

An enlarged prostate is most common among older men, and your risk increases as you age, says Rhett Jensen, assistant administrator at Horizon Ridge Nursing and Rehabilitation Center. Eating well and exercising may help you avoid diabetes and obesity, which in turn can lower your chances of having an enlarged prostate.

Its normal to have trouble getting an erection once in a while, but you should be concerned if it happens regularly. Erectile dysfunction can not only have an effect on your emotional well-being, but it could also be a sign of serious cardiovascular problems. It can be caused by a variety of factors, including depression, anxiety, obesity, cardiovascular disease and other issues. Talking to your doctor is critical to get to the root cause and find the right treatment.

Low testosterone levels can get in the way of getting a full erection, but this hormone is involved in far more than your sex drive. Having low levels of testosterone can also lead to a loss of body hair and muscle, and it can cause mood changes and a drop in energy. Over time, low testosterone could even lead to osteoporosis. Talk to your doctor about possible treatments for underlying conditions or testosterone replacement if needed.

Of course, heart disease isnt exclusive to men, but its still worth mentioning here. Heart disease is the leading cause of death for men, accounting for 25% of male fatalities. Even more troubling, half the men who die from heart problems do so without any prior symptoms. Those regular checkups at the doctors office can help you know your risk and keep you on track with healthy lifestyle choices.

Going to the doctor for a checkup doesnt end once you hit adulthood. Take charge of your health and dont hesitate to talk to your doctor if you experience symptoms of these or other conditions.

Dr. Amy Osmond Cook is a health care technology consultant and VP of marketing at Simplus, a platinum Salesforce partner.

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Watch out for these five men's health conditions - Daily Herald


Nov 19

Global Testosterone Replacement Therapy – How the Market Will Witness Substantial Growth in the Upcoming years? – Hitz Dairies

An Inclusive comprehension of Testosterone Replacement Therapy Market addressing structure, scope, potential, and growth prospects.

In a nutshell , the Acquire Market Research Testosterone Replacement Therapy Market report provides an in-depth insight of the market capturing all important parameters including, Market Dynamics, Market Drivers, business Opportunities, Market Share regional and global, Price and Gross Margin, Competitive Landscape and Profile, New Project Feasibility Analysis, General Analysis and Suggestions on New Project Investment.

With the slowdown in world economic growth, the Testosterone Replacement Therapy industry has also suffered a certain impact, but still maintained a relatively optimistic growth, the past four years, Testosterone Replacement Therapy market size to maintain the average annual growth rate of -0.0063971136945 from 1900.0 million $ in 2014 to 1840.0 million $ in 2018, Our analysts believe that in the next few years, Testosterone Replacement Therapy market size will be further expanded, we expect that by 2023, The market size of the Testosterone Replacement Therapy will reach 1500.0 million $.

Market Segmentation:

Manufacturer Detail: AbbVie, Endo International, Eli lilly, Pfizer, Actavis (Allergan), Bayer, Novartis, Teva, Mylan, Upsher-Smith, Ferring Pharmaceuticals, Kyowa Kirin, Acerus Pharmaceuticals

Product Type Segmentation: Gels, Injections, Patches

Industry Segmentation: Hospitals, Clinics

Testosterone Replacement Therapy Market

The Testosterone Replacement Therapytradereport offers a highly qualitative analysis of regional divisions inthe Global Report with classifications, Market definitions and Market size,productionprocesses,pricestructures, developmental policies, and plans. The statistics arewellconferredwithin thereportwith the use of statistical graphs, diagrams, pie charts, andalternativeillustrations and representations withrelation tothe presentTrends, Dynamics, and Business Scope & important factors of the market.

Key Highlights fromTestosterone Replacement TherapyMarket Study:

Revenue and Sales Forecast:Informationon historical revenue and sales volume isconferred, andadditional informationis quantified withtop-downandbottom-upapplications to anticipate the complete and exact market size and forecast numbers for key regionsenclosedwithin thereporttogether withorganized and well-recognizedvarietiesand end-useIndustrial application and trade. Moreover,regulativepolicies andeconomicfactorsare considered in Testosterone Replacement Therapytrade evolution andprognosticativeanalysis.

Manufacturing Analysis:The report is beinganalyzedof assortedproducttypesand applicationspresently. The Testosterone Replacement Therapy market puts forth documentation defining theproduction processanalysisvalidvia primarydata accumulated throughtradespecialistsand Keyofficersof profiledfirms.

Competition Major key playersstudied on the basis of their company profile, capacity, product portfolio, product/service price, sales, and cost/profit.Demand & Supply analysis and outcomes Testosterone Replacement Therapyreport, in addition, discusses distribution and channels, Production values, Consumption ratios & EXIM** (Export & Import). ** If applicableThe current day Trends, Demographics, Illustrations, Product Portfolio, Geographical distribution, and Regulatory Framework of the Testosterone Replacement TherapyMarket have also been taken into account in the in-depth study.

Introduction about GlobalTestosterone Replacement Therapy:

Global Testosterone Replacement Therapy Market Size, Drivers (Sales) Market Share by Type (Product Category) in 2019.Testosterone Replacement Therapy Market by Application/End Users.Global Testosterone Replacement Therapy Sales (Volume) & Market Share Comparison by ApplicationsGlobal Testosterone Replacement Therapy Sales & Growth Rate (2019-2023).Testosterone Replacement Therapy Competition by Players/Suppliers, Region, Type, and Application.Testosterone Replacement Therapy(Volume, Value and Sales Price) table defined for each geographic region defined.Global Testosterone Replacement Therapy Players/Suppliers Profiles and Sales Data.Additionally, Company Basic Information, Manufacturing Base and Competitors list are being provided for every listed manufacturer.

Market Sales, Revenue, Price and Gross Margin (2019-2023) table for each product type which includes:

Manufacturing Cost AnalysisKey Vendors and Raw Materials Analysis & Price TrendsSupply Chain, Demand-Supply Analysis, Sourcing Strategy and Downstream Buyers, Industrial Chain Analysis

Read Also: 1. Facility Management Market Report: How Market Will Increase in Given Forecast Period by Analysing Current Trends?

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3. Why Shipping kitchens Market trending in recent times? Breakdown by Type | Application |Manufacturers

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Global Testosterone Replacement Therapy - How the Market Will Witness Substantial Growth in the Upcoming years? - Hitz Dairies


Nov 19

Testosterone Replacement Therapy Market 2024 : detailed survey of the key competitors and the leading players – Downey Magazine

The research report on Global Testosterone Replacement Therapy Market delivers major statistics of the global market and it also offers a valuable source of direction and guidelines for individuals as well as industries interested in the Global Testosterone Replacement Therapy Market. In addition, the Global Testosterone Replacement Therapy Market research report provides a comprehensive analysis of the several factors such as regions, manufacturers, types, market size, and market aspects contributing to the Market growth. The analysis of Market will useful for consumers to identify the number of factors which are responsible for encouraging and governing the registering growth of the Market. This report will also help to different manufacturers to recognize their competitor and to gain their position in the global market.

Get sample of the report @ https://www.orbismarketreports.com/sample-request/44691

Key Players include in the report are given below:AbbVieEndo InternationalEli lillyPfizerActavis (Allergan)BayerNovartisTevaMylanUpsher-SmithFerring PharmaceuticalsKyowa KirinAcerus Pharmaceuticals

In addition, the Global Testosterone Replacement Therapy Market represents an in-depth competitive landscape, growth opportunities, and market shares with the help of product type, key companies, application, and regional analysis. Likewise, the Global Testosterone Replacement Therapy Market research report also covers a complete analysis of the regional and global market with the several strategies which are implemented by leading players. Furthermore, the Market report studies the number of different top manufacturers which are offering better services to their consumers. Likewise, the Global Testosterone Replacement Therapy Market report highly focuses on the analytical study as well as the geographical study of the Market. Hence, the study of market competition includes the details related to the business insights, sales data, company, and the product specification which is required for the number of vendors and stakeholders.

Product Type segmentation:GelsInjectionsPatchesOther

In addition, the Global Testosterone Replacement Therapy Market search report covers the market status, key market, future predictions, market growth opportunity, and key players. Likewise, the Global Testosterone Replacement Therapy Market report analyses the Indoor Location Application Platform advancements in the regions such as North America, Southeast Asia, Europe, and Central and South America. Additionally, the Market research report discusses the major market drivers which are influencing the market challenges, market growth, market opportunities, and the several risks facing by the major vendors across the world. This report also includes the number of emerging trends and its positive impact on the current as well as future market development.

Application type segmentation:HospitalsClinicsOthers

Make an enquiry of report @ https://www.orbismarketreports.com/enquiry-before-buying/44691

Furthermore, the Global Testosterone Replacement Therapy Market report prepared with several research methodologies on the basis of Porters Five Forces and SWOT analysis. Moreover, the Market research report offers the huge number of tools which are consists to measure the performance of the vendors, manufacturers as well as consumers. Hence, the Market report is underlying the details such as competition of the industry as well as individual developments aiding in opting the audience for the business.

Regional segmentation:AmericasUnited StatesCanadaMexicoBrazilAPACChinaJapanKoreaSoutheast AsiaIndiaAustraliaEuropeGermanyFranceUKItalyRussiaSpainMiddle East & AfricaEgyptSouth AfricaIsraelTurkeyGCC Countries

dditionally, the Global Testosterone Replacement Therapy Market report comprises the in-depth study of the market segmentation such as types and applications. However, sub-segments studying in this report are crucial for knowing the preference of the shifting market demands. Likewise, the research Global Testosterone Replacement Therapy Market report provides the deep study of the sales medium channels, traders, dealers, distributors at global as well as local level. Moreover, the Global Testosterone Replacement Therapy Market report.

Toc of report1 Scope of the Report1.1 Market Introduction1.2 Research Objectives1.3 Years Considered1.4 Market Research Methodology1.5 Economic Indicators1.6 Currency Considered

Get full overview of report @ https://www.orbismarketreports.com/global-testosterone-replacement-therapy-market-growth-2019-2024

2 Executive Summary2.1 World Market Overview

About Us:With unfailing market gauging skills, Orbis Market Reports has been excelling in curating tailored business intelligence data across industry verticals. Constantly thriving to expand our skill development, our strength lies in dedicated intellectuals with dynamic problem solving intent, ever willing to mold boundaries to scale heights in market interpretation.

Contact Us:Hector CostelloSenior Manager Client EngagementsAddress:- 6200 Savoy Drive,Suite 630 Houston, TX 77036

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Testosterone Replacement Therapy Market 2024 : detailed survey of the key competitors and the leading players - Downey Magazine


Nov 16

Crush Your Fitness Goals with This Fat Burner and Testosterone Booster – Men’s Journal

Mens Journal aims to feature only the best products and services. We update when possible, but deals expire and prices can change. If you buy something via one of our links, we may earn a commission.Questions? Reach us at shop@mensjournal.com.

We all need a boost once in a while. If youre having trouble dropping those last few pounds, maintaining a ripped physique, or just motivating to get off the couch and work out, try Modern Man v.3 Intense 2-in-1 Thermogenic and Testosterone Support.

This is far more than your typical testosterone booster. Modern Man delivers fast-acting results you can see and feel, ultimately enhancing your flow state to keep you in the zone and reach your fitness goals. If youre looking to get ripped, this is the stuff you need to take your fitness over the top. It transcends both testosterone boosters and fat burners.

If you find yourself in an endless cycle of stress, fatigue, and irritability, rest assured youre not alone. All guys go through this. How do some men stay positive, energized and focused? Modern Man can help.

A constant state of stress can torpedo your natural testosterone production. With less testosterone, youre more prone to store fat, have trouble building muscle, experience brain fog, and lose your drive.

With muscle-preserving, fat-burning ingredients and natural testosterone support, bodybuilding experts and business professionals alike swear by Modern Man. Its formulated with a very specific purpose: to help you reach your fitness goals. Getting in shape and achieving your goals adds confidence, which aids in natural testosterone production.

So break the cycle of stress and fatigue. Get Modern Man.

Its more than just testosterone. By combining some of the top, most researched ingredients recommended by professional biohackers, Modern Mans focus-enhancing complex provides a daily brain boost. Multiple nootropics work to boost cognitive function and increase your attention to detail. You will bust out of whats known as brain fog and feel more alert and energetic in your mind. And that will help you be more energetic physically.

And its more than just a brain boost. Modern Man uses clinically studied ingredients like KSM 66, ashwagandha, and Eurycoma Longifolia to support your lean physique and unleash raw power.

And its is made for daily use. So even if youre frequently on-the-go or traveling, you can still supply your body with what it needs on a daily basis to stay strong.

Modern Man will help you optimize your bodys capacity for stress relief, too. So negative thoughts and anxiety cant bring you down. Youll feel calmer in the face of adversity and boost your mood because Modern Man supports healthy dopamine production to further keep you in a positive state of mind.

With over 1,200 reviews and an impressive 4.3-star rating by real users, its safe to say that Modern Man works for a ton of men. Break out of your downward spiral, and be the Modern Man you were born to be.

Check out all the great products and gear we recommend to Mens Journal readers

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Crush Your Fitness Goals with This Fat Burner and Testosterone Booster - Men's Journal


Nov 16

Acerus Reports Third Quarter and Year-to-Date Fiscal 2019 Financial Results – Business Wire

TORONTO--(BUSINESS WIRE)--Acerus Pharmaceuticals Corporation (Acerus or the Company) (TSX:ASP; OTCQB:ASPCF) today reported its financial results for the three- and nine-month period ended September 30, 2019. Unless otherwise noted, all amounts are in US dollars and are prepared in accordance with International Financial Reporting Standards (IFRS).

Third Quarter Highlights

In anticipation of the closing of the A&R Agreement, we have begun the process of standing-up both a US market access team and specialty sales organization to co-promote NATESTO to the United States market. This expansion of our footprint to enter the United States market confirms our mens health strategy and truly establishes Acerus as a globally focused company headquartered in Canada, not just a company servicing the Canadian marketplace, said Ed Gudaitis, President and Chief Executive Officer of Acerus. We are also excited about the results of a clinical study showing that NATESTO increases serum testosterone and improves symptoms while maintaining normal semen parameters in men with low testosterone. This positive study, presented initially by Dr. Ranjith Ramasamy, MD, Associate Professor and Director of Reproductive Urology at the University of Miami School of Medicine, at the American Society for Reproductive Medicine Conference on October 17, 2019, and subsequently at an Acerus Key Opinion Leader presentation in New York City on October 30, 2019, clearly differentiates NATESTO from other approved testosterone therapies. We are very excited by the outcomes of this study and will look to further develop the growing evidence-base supporting NATESTO.

Summary of Results for the Three Months Ended September 30, 2019 (compared to the Three Months Ended September 30, 2018 unless otherwise noted)

Total revenue in the quarter was negative $0.2 million compared to $1.6 million in the third quarter of 2018. This decline is due to a $0.8 million drop in Estrace and UrivarxTM product revenues and the net impact of $0.6 million in Q3-2019 for returns associated with the delay in returning NATESTO to the Canadian and South Korean markets (previously it was assumed that the product would be replaced rather than returned) and reversing the Q2-2019 $0.1 million charge to revenue discounts for incentives to customers to accept replacement product.

On August 2, 2019, we announced that we would voluntarily replace certain NATESTO lots released in the Canadian and South Korean markets, which was expected to cause temporary shortages in those markets. We have identified four commercial lots of NATESTO released in the Canadian and South Korean markets that were found to be non-conforming during long-term stability studies, even though such lots were fully in-specification at the time of release. This post-release non-conformity is not harmful to the patient, but may result in difficulties in dispensing. Acerus made minor modifications to the manufacturing process that appear to have resolved the previously identified issues and has produced a new commercial batch of Natesto. On November 1, 2019, we announced that Health Canada classified the changes as level I, requiring the submission of a SNDS. Should Health Canada utilize the full regulatory allotted time for reviewing a SNDS, Acerus would expect the Revised Batch to be released in the Canadian Market in Q1-2021. In Q2-2019, we had previously impaired inventory by $0.3 million and accrued $0.5 million related to replacing products, discounts and potential returns due to the issue described above. However, due to the additional delays, the Company reversed the previous accruals related to discounts and replacement of product and has accrued $0.7 million for returns in the current quarter.

The following table indicates the revenue by product for the quarter (in US$000s):

Difference

$

$ 80

$ 172

$ (92)

(159)

364

(523)

(296)

-

(296)

(375)

536

(911)

203

883

(680)

5

164

(159)

$ (167)

$ 1,583

$ (1,750)

Gross margin declined by $0.8 million to negative $0.04 million compared to the prior year quarter. The current figure reflects the accrual for product returns described above and the reversal of the $0.4 million charge to cost of goods made in Q2-2019 when it was expected that the Company would replace the recalled NATESTO product.

Selling, general and administrative expenses (SG&A) increased to $3.2 million from $2.2 million in the prior year period. The current quarter reflects costs of $2.1 million in anticipation of the NATESTO United States A&R Agreement closing and subsequent launch. Absent this charge, SG&A expenses were $1.1 million or 50% lower than the comparable prior year period, reflecting decreased marketing and selling expenses related to NATESTO Canada and UriVarxTM and decreased salaries and benefits costs due to reductions in commercial headcount and reductions in bonus accrual. The Company will continue to review expenses and make adjustments where necessary in light of the recent recall and SNDS requirement. In particular, Acerus will be streamlining its future operating expenses to focus on the following key priorities: 1) the standing up of the US organization in anticipation of the go-live of the A&R Agreement, 2) the approval by Health Canada and launch of avanafil in the Canadian market, 3) supporting our global partners who are launching NATESTO in their respective markets and 4) strengthening the management of our third-party manufacturing network.

Research and development ("R&D") expense was $0.6 million for the current quarter, a slight decline from the $0.8 million for the prior year period.

Earnings before interest, tax, depreciation and amortization (EBITDA)1 was a loss of $3.7 million compared to an EBITDA loss of $1.6 million for the prior year quarter. Adjusted EBITDA1, was a loss of $3.4 million for the quarter compared to a loss of $1.5 million for the prior year period.

The Company incurred a net loss of $4.6 million or $(0.02) per share for the quarter compared to a loss of $2.9 million or $(0.01) per share for the third quarter of 2018.

Cash as of September 30, 2019 was $4.1 million compared with $3.8 million on December 31, 2018, reflecting the proceeds of a CDN$4.5 million private placement in Q1-2019, and a US$5.0 million subordinated debt facility entered into in Q3-2019 between the Company and First Generation Capital Inc., a company affiliated with the Chairman of the Board of Directors of the Company, offset by cash used in operations.

Summary of Results for the Nine Months Ended September 30, 2019 (compared to the Nine Months Ended September 30, 2018 unless otherwise noted)

NATESTO USA UPDATE

As indicated above, the Company and Aytu Bioscience jointly announced on July 30, 2019, that they had signed an amended and restated license agreement to allow Acerus to enter the US market directly and co-promote NATESTO to the specialist (urology and endocrinology) market. Under the terms of the new agreement, Aytu returns the NDA for NATESTO in the US back to Acerus. Going forward, Acerus will assume all regulatory and clinical responsibilities and costs for the product in the US Acerus will take on a more expansive role in matters such as US marketing, reimbursement and medical strategy as part of the companies joint commercialization committee. Aytu will retain its primary care sales force and will continue to book all product net revenue while serving as the exclusive US supplier of NATESTO to wholesalers, pharmacies and other customers that receive a direct shipment. Financial payments will be based upon a tiered level of net revenue, post cost of goods sold (COGS), based on annual sales performance in the respective Acerus and Aytu Sales Channels. This transaction is conditional on Acerus raising at least US$10 million in any combination of debt or equity by no later than January 29, 2020. In anticipation of the condition being satisfied, the Company has begun working with its partner, Syneos Health, to facilitate a launch by Acerus in early 2020.

Conference Call

Shareholders are reminded that the conference call to discuss the Companys results for the three- and nine-month period ending September 30, 2019 will be held on Thursday, November 14, 2019 at 8:30 a.m. Eastern Time. To access the call live, please dial 416-340-2219 or 1-800-478-9326. Listeners are encouraged to dial in 10 minutes before the call begins to avoid delays.

A replay of the conference call will be available until 11:59 p.m. Eastern Time on Thursday, November 21, 2019 by dialing 905-694-9451 or 1-800-408-3053, using access code: 2401991#.

About AcerusAcerus Pharmaceuticals Corporation is a Canadian-based specialty pharmaceutical company focused on the development, manufacture, marketing and distribution of innovative, branded products that improve patient experience, with a primary focus in the field of mens health. The Company commercializes its products via its own salesforce in Canada, and through a global network of licensed distributors in the US and other territories.

Acerus shares trade on TSX under the symbol ASP and on the OTCQB under the symbol ASPCF. For more information, visit http://www.aceruspharma.com and follow us on Twitter and LinkedIn.

1 Non-IFRS Financial Measures - EBITDA and Adjusted EBITDAThe non-IFRS measures included in this press release are not recognized measures under IFRS and do not have a standardized meaning prescribed by IFRS and may not be comparable to similar measures presented by other issuers. When used, these measures are defined in such terms as to allow the reconciliation to the closest IFRS measure. These measures are provided as additional information to complement those IFRS measures by providing further understanding of our results of operations from our perspective. Accordingly, they should not be considered in isolation nor as a substitute for analysis of our financial information reported under IFRS. Despite the importance of these measures to management in goal setting and performance measurement, we stress that these are non-IFRS measures that may have limits in their usefulness to investors.

We use non-IFRS measures, such as EBITDA and Adjusted EBITDA to provide investors with a supplemental measure of our operating performance and thus highlight trends in our core business that may not otherwise be apparent when relying solely on IFRS financial measures. We also believe that securities analysts, investors and other interested parties frequently use non-IFRS measures in the valuation of issuers. We also use non-IFRS measures in order to facilitate operating performance comparisons from period to period, prepare annual operating budgets, and to assess our ability to meet our future debt service, capital expenditure and working capital requirements.

The definition and reconciliation of EBITDA and Adjusted EBITDA used and presented by the Company to the most directly comparable IFRS measures follows below:

EBITDA is defined as net (loss)/income adjusted for income tax, depreciation of property and equipment, amortization of intangible assets, interest on long-term debt and other financing costs, interest income, licensing revenue and changes in fair values of derivative financial instruments. Management uses EBITDA to assess the Companys operating performance.

Adjusted EBITDA is defined as EBITDA adjusted for, as applicable, royalty expenses associated with triggering events, milestones, share based compensation, impairment of intangible asset, foreign exchange (gain)/loss and the impact of charges related to a product recall. We use Adjusted EBITDA as a key metric in assessing our business performance when we compare results to budgets, forecasts and prior years. Management believes Adjusted EBITDA is an alternative measure of cash flow generation than, for example, cash flow from operations, particularly because it removes cash flow fluctuations caused by extraordinary changes in working capital. A reconciliation of net (loss)/income to EBITDA (and Adjusted EBITDA) is set out below.

2019

2018

2019

2018

$

(4,612

)

$

(2,871

)

$

(12,246

)

$

(13,735

)

-

2

-

2

177

447

642

1,300

64

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Acerus Reports Third Quarter and Year-to-Date Fiscal 2019 Financial Results - Business Wire


Nov 16

Why men who compete as female will always have an unfair advantage over real women – Lifesite

November 15, 2019 (WORLD Magazine) Activists appear to have two approaches to controlling the narrative concerning transgender athletes' successes in women's sports: Attack the critics, or keep things hush-hush.

Neither has proven particularly effective at quelling a controversy that needn't exist, isn't going away, and really has only one solution.

Rachel (formerly Rhys) McKinnon went on the offensive after defending his 200-meter sprint title in the women's 3539 age group at the Masters Track Cycling Championships in Manchester, England, in late October. After setting a world record during qualifying, McKinnon won the race for the second straight year by four-tenths of a second, or roughly 15 meters in a race typically decided by centimeters.

In the wake of victory, McKinnon blasted those who decry the unfairness of biological males defeating women: "I have yet to meet a real champion who wants trans women banned," the 37-year-old Canadian said. "If you win because bigotry got your competition banned ... you're a loser."

Meanwhile, publicity handlers tried in vain to keep June (formerly Jonathan) Eastwood's transgender status quiet after the Big Sky Conference named the University of Montana cross-country runner its Female Athlete of the Week in late October. Eastwood received the honor after placing second in the women's race at Santa Clara University's Bronco Invitational in Sunnyvale, Calif.

In touting Eastwood's accolade, both the Big Sky and Montana websites failed to mention that Eastwood had competed as a male with moderate success as recently as last year. Eastwood's bio on the Montana women's cross-country website omits the senior's prior running experience entirely.

Something similar happened with CeCe (formerly Craig) Telfer of New Hampshire's Franklin Pierce University afterhe wonthe NCAA Division II title in the women's 400-meter hurdles last spring. And yet, Eastwood's transgender status, like Telfer's, still surfaced not least becauseThe Missoulian, the newspaper that covers Montana athletics in the university's home city of Missoula, ran a preseason profile hailing Eastwood's history-making turn as the NCAA's first openly transgender cross-country runner.

While Union Cycliste Internationale, cycling's international governing body, has a testosterone threshold that biological males cannot exceed if they wish to compete as women, the NCAA has none: The governing body for major-college sports simply requires biologically male athletes to take testosterone-suppressing hormones for at least one year. McKinnon and Eastwood have apparently done enough to comply with the rules of their sports' respective governing bodies.

Still, science is proving that even after taking testosterone-suppressing hormones, biologically male athletes retain competitive advantages over women:The Journal of Medical Ethicspublished a study in August stating that biological males do not lose significant muscle mass or power after suppressing their testosterone levels below International Olympic Committeestandards. The study also found that biological males who suppress their testosterone levels can retain and rebuild their muscle mass, power, and strength through training.

Some, like McKinnon, say transgender athletes should be able to compete according to their gender identity and without suppressing their testosterone levels. They might counter any arguments about unfairness by pointing to Eastwood's performance at the Big Sky cross-country championships on Nov. 2: He placed eighth proof that biological males are not automatically better than biological women in head-to-head competition.

However, Eastwood never placed higher than 24that a Big Sky championship meet when running against men. In other words, even if he wasn't faster than every woman who competed on Nov. 2, he was still faster than most and he displaced one from earning all-conference honors.

In light of the study's findings, the only real way to ensure competitive fairness in women's sports is to keep men out.

Published with permission from WORLD Magazine.

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Why men who compete as female will always have an unfair advantage over real women - Lifesite


Nov 16

Hormone therapy offered by Student Health Service – UWEC Spectator

Through hormone replacement therapy, transgender women can receive estrogen to counteract testosterone and transgender men can receive testosterone to counteract estrogen, said Patricia Kress, the medical director of Student Health Service on campus.

Its a critical resource we have here on campus, Chris Jorgenson, the director of the Gender and Sexuality Resource Center, said.

Jorgenson said on campus, students are able to initiate hormone therapy if they have not yet done so prior to coming to campus, or are able to continue hormone therapy if they have already started elsewhere.

Its critical that we support trans people not only in social transitioning but if there are any medical transitions that they want to undertake, he said.

The mental health outcomes are incredible for people who are allowed to take steps to align themselves physically with who they are and how they identify, Jorgenson said.

If they are coming to Student Health Service on campus, visits are completely free, Kress said.

Right now if a transgender male comes in and needs this routine lab work done during a visit, the price is $74, Kress said.

The routine lab consists of checkups six months after the first meeting, 12 months out, and then once a year after that.

For transgender men, clinicians need to test testosterone levels to see if the medicine is working and to keep track of cholesterol, complete blood count, kidney function and blood sugar, she said.

The first year is a little expensive but once you get through that its not so bad, Kress said.

Outside of the university, that $74 panel would easily cost $700 to $1000, so here on campus, the treatment is much more inexpensive compared to other clinics, Kress said.

For transgender females, the blood tests are around $50 because we dont have to do that testosterone level, she said.

For some of these students whose parents cut them off, they have no financial support.

We dont want to make things harder for them by having the treatment be so expensive, Kress said.

The clinicians monitor the students feedback to the dosages very closely, Kress said.

When hormone therapy starts it can be a very exciting time but it also can be rocky with dips in the road, Kress said.

There are counseling services available throughout the process to make sure that the students receiving the treatment feel safe and supported and that the transgender students are doing whats best for them, Kress said.

Its kind of amazing because some students, after you give them that first dosage of the hormone they need, theyre like oh my gosh, a piece of the puzzle has been finally found. Its really powerful, she said. Kress spends a full hour with students at the first appointment, a half-hour at the next two meetings and then sees them in a follow-up within a month, she said.

We have plenty of time to be with them and not be rushed and to explore any concerns either of us would have the students or myself, Kress said.

Hormone therapy is not nearly as groundbreaking as people seem to believe, Jorgenson said, as prescribing hormones has been the norm for a long time.

Gender is very complicated, Jorgensen said.

There has been a lot of research conducted in order to further understand gender identity, whether it is merely the result of choices that we make or if it is a complex aspect of identity that is rooted in our brain, Jorgensen said.

One prominent hypothesis on the basis of gender dysphoria is that sexual differentiation of the genitals occurs separately from sexual differentiation of the brain in utero, making it possible that the body can veer in one direction and the mind in another, according to an article on The Scientist website, Are the Brains of Transgender People Different from Those of Cisgender People.

At the root of this idea is the notion that gender itselfthe sense of which category one belongs in, as opposed to biological sexis determined in the womb for humans, the article said.

We have been operating at this false assumption that ones body automatically presupposes their gender identity, Jorgenson said, and the research thus far since the early 90s just has not borne that out.

Erickson can be reached at [emailprotected]

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Hormone therapy offered by Student Health Service - UWEC Spectator


Nov 16

Ford v Ferrari: A Rollicking Tale of Fast Cars and Capitalism – The Atlantic

The film follows Carroll Shelby (played by Matt Damon), a retired driver turned engineer who is contracted by the execs Henry Ford II (Tracy Letts) and Lee Iacocca (Jon Bernthal) to build out Fords racing division. Shelby brings aboard Ken Miles (Christian Bale), a stubborn Brit with a colossal chip on his shoulder and an attitude far from the anodyne politeness thats expected at Ford. Much of the movies two-and-a-half-hour running time revolves around Shelbys corporate battles to convince his bosses that Miles belongs in the drivers seat. But the heart of the film is in the oily garages below the executive suites, where Fords mechanics and drivers strive to create a machine worthy of challenging Ferraris perfection.

Whenever Mangold and his cinematographer Phedon Papamichael are shooting racing footage, Ford v Ferrari practically vibrates off the screen. Car racing in the 1960s was still intense and raw (the technology behind functioning brakes was primitive at best), and Mangold works to convey just how death-defying and brutal the day-long Le Mans race was for a driver. Fords offices, meanwhile, are burnished and beautiful tableaus of mid-century modernity, expensive-looking exhibitions of American wealth that are just as crucial to the companys image as the factory floor. Letts gives a quietly nasty performance as Ford II, emphasizing the CEOs vanity and churlishness as much as the resources at his disposal.

The biggest conflict in Ford v Ferrari isnt the automakers contest, but Shelby and Miless struggle to maintain their integrity while pleasing their corporate overlords. Amid all the testosterone, characters like Mollie Miles (Caitriona Balfe), Kens wife, have few opportunities to shine. Though the script (by Jason Keller and Jez and John-Henry Butterworth) tries to give Balfe a few scenes that assert her personality, shes largely confined to the stock role of frustrated but supportive partner. Noah Jupe, who plays Ken and Mollies plucky son, Peter, gets similarly lost.

Still, the climax of the film, which details all the unpredictable twists of the race itself, brings home the themes Mangold has been working to flesh out. Ford v Ferrari couldve been an easy tale of a dark horse winning against a runaway sporting favorite, but the reality of the 1966 Le Mans contest was much stranger. The movie rejects hackneyed storytelling tropes to depict the limits of ingenuity in the face of capitalistic might, and the result is a rich crowd-pleaser with a pessimistic edge.

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Ford v Ferrari: A Rollicking Tale of Fast Cars and Capitalism - The Atlantic


Nov 13

Testosterone therapy prescription linked to increased VTE risk in JAMA study – Specialty Medical Dialogues

The researchers conducted the study to evaluate whether the clinical prescription of testosterone therapy was associated with short-term risk of venous thromboembolism in men with and without hypogonadism or not. They found that Testosterone therapy is associated with increased risk for venous thromboembolism (VTE) in men. The case-crossover study has been published in JAMA Internal Medicine.

According to the American Heart Association, Venous thromboembolism (VTE) refers to a blood clot that starts in a vein. It is the third leading vascular diagnosis after a heart attack and stroke and includes Deep vein thrombosis andPulmonary embolism .

The researchers used insurance claims databases, researchers identified roughly 40,000 men without cancer whod experienced a VTE. Out of them, nearly 8% were diagnosed with hypogonadism. Each patient served as his own control. The immediate 6 months before the VTE was the case period, and the 6 months before that was the control period.

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A claim for testosterone therapy was more common in the 6 months before VTE, compared with the control period, both for men without hypogonadism (0.8% for case period vs. 0.5% for control period) and for those with (34% vs. 22%).

It was found that the use of testosterone therapy in the 6-month case period was associated with an increased risk of venous thromboembolism among men with and without hypogonadism. The testosterone prescription during the case period was associated with roughly double the risk for VTE. The risk was highest in the first 3 months of starting testosterone.

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The authors concluded that testosterone therapy was associated with an increase in short-term risk for VTE among men with and without hypogonadism, with some evidence that the association was more pronounced among younger men. These findings suggest that caution should be used when prescribing testosterone therapy.

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JAMA Intern Med.Published online November 11, 2019. doi:https://doi.org/10.1001/jamainternmed.2019.5135

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Testosterone therapy prescription linked to increased VTE risk in JAMA study - Specialty Medical Dialogues



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