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Nov 13

New book refutes ‘boys will be boys’ – Futurity: Research News

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A new book traces the origins of the claim that boys will be boysand refutes it.

Thirty years ago, in downtown Mexico City, Matthew Gutmann took a picture of a man holding a baby. Little did he know then that photo would launch a decades-long career studying men and masculinity around the world.

I showed that photo to a bunch of people in the United States, and I kept getting vehement reactions, says Gutmann, a professor of anthropology at Brown University.

People said, This is unreal. This is an aberration. I tried to explain to an art editor at a university press that the photo was candid and not posed, and he says, Thats impossible. Mexican men are machos; they dont carry babies.'

For Gutmann, that moment launched a quest to learn more about men and masculinity in Mexico. He has since studied the state of sexual and reproductive health across Latin America, investigated the concept of masculine loyalty among American veterans who fought in Iraq, and observed changes in workplace gender standards in urban China, where he currently teaches as a visiting professor.

In some ways, the book Are Men Animals? (Basic Books, 2019) is a distillation of all that Gutmann has learned since he took that fateful photo as a graduate student. His book takes the reader on a world tour, examining the women-only subway cars of Mexico City, the barrio of Santo Domingo and the so-called marriage market in Shanghai to demonstrate that theres no single definition of masculinity or manliness.

Ultimately, Gutmann says, he hopes Are Men Animals? emphasizes that men are more than testosterone and Y chromosomesthat theyre made as much by society as by biology.

The great feminist Simone de Beauvoir once wrote about women, Their biology is not their destiny,' Gutmann says. I think we need to say something similar about men. Mens biology is not their destiny, either.

Ahead of the release of Are Men Animals?, Gutmann answered a few questions about the book, his research, and the future of masculinity:

Original Study

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New book refutes 'boys will be boys' - Futurity: Research News


Nov 13

Value and Size Of Testosterone Replacement Therapy Market From 2019 To 2024: Detailed Research Report – The Denton Chronicle

Testosterone Replacement Therapy Market to 2024: Deep Analysis

The report offers a complete research study of the globalTestosterone Replacement Therapy Marketthat includes accurate forecasts and analysis at global, regional, and country levels. It provides a comprehensive view of the global Testosterone Replacement Therapy market and detailed value chain analysis to help players to closely understand important changes in business activities observed across the industry. It also offers a deep segmental analysis of the global Testosterone Replacement Therapy market where key product and application segments are shed light upon. Readers are provided with actual market figures related to the size of the global Testosterone Replacement Therapy market in terms of value and volume for the forecast period 2019-2024.

The following Companies as theKey playersin the Global Testosterone Replacement Therapy Market Research Report are AbbVie, Endo International, Eli lilly, Pfizer, Actavis (Allergan), Bayer, Novartis, Teva, Mylan, Upsher-Smith, Ferring Pharmaceuticals, Kyowa Kirin, Acerus Pharmaceuticals.

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On the basis of product, this report displays the production, revenue, price, market share and growth rate of each type, primarily split intoGels, Injections, Patches.

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Global Testosterone Replacement Therapy Market Forecast:Readers are provided with production and revenue forecasts for the global Testosterone Replacement Therapy market, production and consumption forecasts for regional markets, production, revenue, and price forecasts for the global Testosterone Replacement Therapy market by type, and consumption forecast for the global Testosterone Replacement Therapy market by application.

Regional Market Analysis:It could be divided into two different sections: one for regional production analysis and the other for regional consumption analysis. Here, the analysts share gross margin, price, revenue, production, CAGR, and other factors that indicate the growth of all regional markets studied in the report.

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Value and Size Of Testosterone Replacement Therapy Market From 2019 To 2024: Detailed Research Report - The Denton Chronicle


Nov 13

Testosterone Replacement Therapy Market 2019| Recent Trends, In-depth Analysis, Market Size Research Report Forecast up to 2026 | Research Industry US…

Global Testosterone Replacement Therapy market report is the first of its kind research report that covers the overview, market dynamics, competitive analysis, and leading players numerous strategies to sustain in the global market. This report covers five top regions of the world and countries within, which shows the status of regional development, consisting of volume, size, market value, and price data.

The report takes a dashboard view of an entire Testosterone Replacement Therapy market by comprehensively analyzing market circumstance and situation and the various activities of leading players in the market such as mergers, partnerships, and acquisitions. This unique report explains the present industry situations that give the crystal-clear picture of the global Testosterone Replacement Therapy market to the clients.

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Market Segmentation

Key players considered in the report include

AbbVieEndo InternationalEli lillyPfizerActavis (Allergan)BayerNovartisTevaMylanUpsher-SmithFerring PharmaceuticalsKyowa KirinAcerus Pharmaceuticals

On the basis of types, the global Testosterone Replacement Therapy market is primarily split into

GelsInjectionsPatchesOther

Based on application, the global Testosterone Replacement Therapy market is primarily split into

HospitalsClinicsOthers

Some of the significant factors such as marketing strategy, factor analysis, cost analysis, industrial chain, distributors and sourcing strategy are included in this report which makes it an exclusive one. The report on the global Testosterone Replacement Therapy market report is compiled by industry experts and properly examined which will highlight the key information required by the clients.

Regional Analysis

A unit of the report has given comprehensive information about regional analysis. It provides a market outlook and sets the forecast within the context of the overall global Testosterone Replacement Therapy market. Research Industry US has segmented the global Testosterone Replacement Therapy market into major geographical regions such as North America, Europe, Asia Pacific, South America, and the Middle East and Africa (MEA). Potential new entrants wishing to target only high growth areas are also included in this informative section of the global Testosterone Replacement Therapy market.

Based on geography, the global Testosterone Replacement Therapy market is divided into North America, Europe, Asia-Pacific, South America, and The Middle East & Africa. North America is further divided in the U.S., Canada, and Mexico, whereas Europe consists of the UK, Germany, France, Italy, and Rest of Europe. India, China, Japan, South Korea, and Rest of Asia-Pacific are the categorization of the Asia-Pacific region. The South America region includes Brazil, Argentina, and the Rest of South America, while The Middle East & Africa is categorized into GCC Countries, Egypt, South Africa, and the Rest of the Middle East & Africa.

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Nov 13

Testosterone Replacement Therapy Industry: Time to Invest in emerging Markets | Endo International, Pfizer, Novartis – News Description

AMA recently published a detailed study of over 180+ pages in its repository on Testosterone Replacement Therapy market covering interesting aspects of market with supporting development scenario till 2025. The study provides market size break-up by revenue and volume* for emerging countries and important business segments along with commentary on trending factors, growth drivers. Profiled players in study from the coverage used under bottom-up approach are AbbVie Inc. (United States), Endo International (Ireland), Eli Lilly and Company (United States), Pfizer (United States), Bayer (Germany), Actavis (Allergan) (United States), Novartis (Switzerland), Teva (Israel), Ferring Pharmaceuticals (Switzerland), Kyowa Kirin (Japan), Mylan (United States)

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Testosterone is responsible for the development of male sexual characteristics and this hormone formed by the testicles. Insufficient production of testosterone causes erectile dysfunction. Testosterone Replacement Therapy (TRT) is generally termed as hormone therapy for men, designed to counteract the effects of reduced activity in the gonads or hypogonadism. Hypogonadism in men is clinical syndrome, which results in the failure of the testes to produce physiological levels of testosterone. Erectile dysfunction arises due to reduce testosterone production to overcome this testosterone replacement therapy is used to improve the problem.

Market Segmentationby Type (Creams or Gels, Patches, Injections, Buccal Adhesives, Implants, Oral), Application (Hospitals, Clinics)

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Whats Trending in Market: Increasing awareness about testosterone substitute therapy

Growth Drivers: Increasing prevalence of hypogonadism in adult men

The need for having an offspring amongst men

Restraints: High possibility of side effects related to testosterone replacement therapy

View Detailed Table of Content @ https://www.advancemarketanalytics.com/reports/46424-global-testosterone-replacement-therapy-market

Country level Break-up includes:North America (United States, Canada and Mexico)Europe (Germany, France, United Kingdom, Spain, Italy, Netherlands, Switzerland, Nordic, Others)Asia-Pacific (Japan, China, Australia, India, Taiwan, South Korea, Middle East & Africa, Others)

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GET FULL COPY OF United States Testosterone Replacement Therapy market study @ USD 2000

And, Europe Testosterone Replacement Therapy market study @ USD 2500 Major Highlights of TOC:

Chapter One: Market Overview

Scope/Objective of the Study

Chapter Two: Executive Summary - Free of Cost

Chapter Three: Market Dynamics USD400

Market Drivers, Market Challenges, Market Trends

Chapter Four: Market Factor Analysis USD400

Supply/Value Chain Analysis, Porters Five Forces, PESTEL analysis, Market Entropy, Patent & Trademark Analysis, Market Development Scenario

Chapter Five and Seven: Global Testosterone Replacement Therapy, by Market Segmentation and Region (value, volume**) (2013-2024) USD2400

Global Testosterone Replacement Therapy

By Type (Creams or Gels, Patches, Injections, Buccal Adhesives, Implants, Oral)

By Application (Hospitals, Clinics)

Global Testosterone Replacement Therapy Region

North America (United States, Canada and Mexico)

Europe (Germany, France, United Kingdom, Spain, Italy, Netherlands, Switzerland, Nordic, Others)

Asia-Pacific (Japan, China, Australia, India, Taiwan, South Korea, Middle East & Africa, Others)

Chapter Six: Global Testosterone Replacement Therapy Manufacturers/Players Analysis USD1200

Competitive Landscape (Direct & Indirect Competitors), Market Share Analysis, Peer Group Analysis (2018), BCG Matrix, Company Profile, Downstream Buyers & Upstream Suppliers

..

Chapter Nine: Methodology/Research Approach, Data Source, Disclaimer

** If applicable

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Testosterone Replacement Therapy Industry: Time to Invest in emerging Markets | Endo International, Pfizer, Novartis - News Description


Nov 13

Nike will look into runner Mary Cain’s allegations of abuse – The Associated Press

Nike will look into runner Mary Cains allegations of abuse while she was part of Alberto Salazars training group. The runner says it reached the point where she started having suicidal thoughts and cutting herself.

Cain joined the disbanded Nike Oregon Project run by Salazar in 2013, soon after competing in the 1,500-meter final at track and fields world championships when she was 17.

Now 23, Cain told The New York Times in a video essay that she joined Nike because she wanted to be the best female athlete ever.

Instead, I was emotionally and physically abused by a system designed by Alberto and endorsed by Nike, she said.

Nike said in a statement these are deeply troubling allegations which have not been raised by Mary or her parents before. Mary was seeking to rejoin the Oregon Project and Albertos team as recently as April of this year and had not raised these concerns as part of that process.

The sportswear giant added it will take the allegations extremely seriously and will launch an immediate investigation to hear from former Oregon Project athletes.

Cain alleged that under Salazars direction she was told to lose weight and he created an arbitrary number of 114 pounds.

He would usually weigh me in front of my teammates and publicly shame me if I wasnt hitting weight, she said.

In 2015, Cain said after a race she told Salazar and the teams sports psychologist she was cutting herself and they pretty much told me they wanted to go to bed. I think for me that was my kick in the head, where I was like, This is a sick system.

Salazar was banned from the sport for four years by the U.S. Anti-Doping Agency for experiments with supplements and testosterone that were bankrolled and supported by Nike, along with possessing and trafficking testosterone. Nike shut down Salazars elite program. In addition, Nike said last month that longtime CEO Mark Parker would leave early next year.

Cain said that young girls bodies are being ruined by an emotionally and physically abusive system. Thats what needs to change.

In trying to cut weight, Cain said she didnt have her period for three years and broke five different bones. Cain also said Salazar wanted to give her birth control pills and diuretics to lose weight, the latter of which isnt allowed in track and field.

I ran terrible during this time, she added in the video. It reached a point where I was on the starting line, and Id lost the race before I started because in my head all I was thinking of was not the time I was trying to hit but the number on the scale I saw earlier that day.

Cain drew overwhelming support from the running community. Shalane Flanagan reached out to her on Twitter, posting: I had no idea it was this bad. Im so sorry (Mary) that I never reached out to you when I saw you struggling. I made excuses to myself as to why I should mind my own business. We let you down. I will never turn my head again.

Cain responded to Flanagan by posting: I cant express how much this meant to me. It was scary to feel so forgotten by a community I devoted my life to. But together we can change things. As athletes, its easy to hand our agency to others, but new coaches can change the system.

At the end of her seven-minute video, Cain said: I genuinely do have hope for the sport and I plan to be running for many years to come. Part of the reasons why Im doing this now is I want to end this chapter and I want to start a new one.

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Nike will look into runner Mary Cain's allegations of abuse - The Associated Press


Nov 13

Sex file: Hard to have sex when you dont feel sexy – Irish Examiner

My husband has put on a lot of weight. I still fancy him, but hes become much less keen on sex. Were in our fifties and he says that its just age thats slowed his libido down. He must feel less sexy, but Im fed up that he wont make any effort to save our sex life.

Although your husband blames his age for his lack of libido, his weight is more likely to be responsible. The issue may be metabolic obesity has a negative impact on testosterone levels but stigma and low self-esteem are equally likely to cause sexual difficulties. Body image is a subjective psychological phenomenon, in that people who are a perfectly normal weight can convince themselves that they are fat, but people who are obese experience much higher levels of body dissatisfaction. It is hard to have sex when you dont feel sexy.

Despite the fact that it clearly does not work, blame and shame are routinely used to try to motivate obese individuals to lose weight.

The discrimination obese people endure is so profound that in her 2015 study Angelina R Sutin found that it was associated with an increased mortality risk of nearly 60%. She concluded that the stigma associated with being overweight or obese shortens life to such an extent that it may be more harmful than actually being overweight or obese.

There is such an intense focus on the health implications of obesity that the psychological, sexual and relational consequences are often forgotten, but many obese people experience some form of sexual dysfunction. Dealing with a triple whammy of obesity, sexual dysfunction and low self-esteem is not easy and although it feels as if your husband is rejecting you, he is actually protecting himself. After all, if he doesnt try to have sex, he avoids the possibility of sexual failure. It is not a sustainable strategy, but nagging him wont help. People dont actively choose to be obese.

It is worth reminding your husband that everyones metabolism slows by 5% each decade, so we all burn about 200 fewer calories a day at age 45 than we did at age 25. Most people also eat about 200 calories more food energy a day than they did 10 years ago, so anyone who doesnt actively fight the flab can put on significant weight.

Because it is much easier to get a fat person fit than it is to get a fat person thin, encouraging your husband to be more active and helping him to make healthier food and drink choices will have a more immediate impact than a diet. Gentle exercise will also boost his serotonin levels and that will help him to feel happier and more positive.

Getting your sex life back on track is important, but he may need help, so he needs to book an appointment with his doctor. His GP will check his heart and his testosterone levels. If they are fine he could get a prescription for Viagra, Cialis or Levitra. The drugs have different active ingredients, but the main difference between them is how long they work for.

Viagra and Levitra give the possibility of an erection for four hours, whereas with Cialis it is 36. Viagra and Cialis have not, to my knowledge, been tested on obese men, but an independent pilot study by Antonio Aversa, which was published in the International Journal of Impotence Research in 2012, evaluated the effects of Levitra on sexual distress in men with obesity. The study found that Levitra improved sexual function and had a positive impact on the participants sexual relationships, so it is probably worth a try.

Send your queries to suzigodson@mac.com

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Sex file: Hard to have sex when you dont feel sexy - Irish Examiner


Nov 11

Testosterone Replacement Therapy Market 2019-2027 Onset of Advanced Technologies to Upsurge the Growth – The Denton Chronicle

The Testosterone Replacement Therapy Market Report is a valuable source of information for corporate strategists. This study contains comprehensive data that enhances the understanding, scope and application of this report. The report contains all the necessary information about the latest innovations, such as: For example, Porters five-pot model analysis and advanced profiles of elite industry participants.

The major players in the Testosterone Replacement Therapy Market investigated in this report are: AbbVie, Inc., Bayer AG, Endo Pharmaceuticals, Inc., Eli Lilly and Company, Kyowa Kirin International plc, Pfizer, Inc., Acerus Pharmaceuticals Corporation, and Perrigo Company plc.

Request a sample copy of this report @ https://www.coherentmarketinsights.com/insight/request-sample/2024

In the developing Markets of the Asia-Pacific, the Middle East, China, India, Japan and Australia, increased development prospects are to be expected due to the enormous potential in the individual countries. The various industry trends and threat factors are carefully examined and described in detail in this Testosterone Replacement Therapy report.

The study will also highlight the industrys key players, their product, business portfolio, Market share, financial status, regional share, segment sales, SWOT analysis, key strategies including mergers and acquisitions, product developments, joint ventures and partnerships, as well as improvements to their latest news.

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Cyclical Dynamics We forecast the dynamics of the industry through analytical and unconventional Market research approaches. Our customers use the information we provide to navigate Market uncertainty and disruption

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Recognizing Emerging Trends Our range of ecosystems helps clients identify current Market trends. We also track possible impacts and disruptions that a Market would experience through a particular emerging trend. Our proactive analysis helps clients benefit from early intervention

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This study addresses some of the issues listed below:

How big is the Testosterone Replacement Therapy Market worldwide?

Which screen size is most preferred by consumers of Testosterone Replacement Therapy?

What type of distribution channel is most preferred by the producers of Testosterone Replacement Therapy?

What is the preferred age group for forwarding Testosterone Replacement Therapy to manufacturers?

What are the key factors that inhibit the growth of the Market, and to what extent are these factors affecting drivers and restraint systems?

How are the regulations affecting the growth of the Testosterone Replacement Therapy Market?

Which is the leading region / country for the growth of the Market? What is the expected growth rate of the leading regions in the forecasting period?

How will the emerging Testosterone Replacement Therapy Market develop in the coming years? How should the consumption pattern develop in the future?

Who are the main players in the global Testosterone Replacement Therapy Market? What is the current Market position of the key players? Who are the emerging players in this industry?

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Testosterone Replacement Therapy Market 2019-2027 Onset of Advanced Technologies to Upsurge the Growth - The Denton Chronicle


Nov 11

Texan Spending Fortune, Hours A Day Trying To Live To At Least 120 Years Old: I Am My Asset – CBS Dallas / Fort Worth

DALLAS (CBSDFW.COM) Hundreds of pills, expensive machines and constant blood testing.

They are among the keys to immortality according the ultra-wealthy who are becoming devout followers of whats known as biohacking.

A rich Dallas and Austin developer is offering CBS 11 News a rare glimpse into the lifestyle.

Ari Rastegar (CBS 11)

Ari Rastegar goes to bed in special clothing on a temperature-regulated bed.

It has this metallic mechanism inside of it that helps flush lactic acid and eliminate inflammation, says Rastegar.

He also wears a mask.

Orange glasses that illuminate the the light so I dont disrupt the circadian rhythms, he says.

Thats just Rastegars nightly routine.

During the day, he takes nearly 150 vitamins customized to his current needs by his doctor.

Rastegar also gets his blood tested monthly.

The 37-year-old has a $15,000 vapor machine thats supposed to reduce stress and another $15,000 machine designed to calm his brain two hours before bedtime.

He says its paying off and making him healthier than ever.

I am my asset, he says.

Ari Rastegar and his vapor machine. (CBS 11)

Biohacking is all part of an effort to extend life beyond anything humans can imagine.

The data will tell you the folks that are living this type of lifestyle are living well in excess of 120 years old, says Rastegar.

The goal of biohacking is to keep strands of DNA from aging.

Rastegar has already spent hundreds of thousands of dollars.

But the real estate developer can afford it with the money he makes as CEO of Rastegar Property.

He owns buildings in Austin and is planning a $100,000,000, 26-story residential tower in the uptown section of Dallas next year.

I dont know if Im trying to live forever. Im trying to live as long as I can contribute, he says.

Rastegars exhausting daily routine also includes a hyperbaric chamber, meditation and he employs a life coach.

Rastegar is one of a growing number of longevity devotees who also undergo hormone therapy.

Others, not Rastegar, have even resorted to blood transfusions and stem cell treatments stay young.

My biological age is now that of about a 4-year-old, he says.

But medical doctors say not so fast when it comes to treatments that promise to slow down aging.

We dont have any long-term evidence-based studies to correlate whatever biohacking techniques people are using to prolong or extend life, yet, says Dr. James Pinckney of Diamond Physicians.

While physicians are cautious, Rastegar says hes seen the proof by lowering his cholesterol and raising his testosterone.

Rastegar along with a number of other millionaires and billionaires are spending vast amounts of their fortunes in the search for immortality.

But he says that doesnt mean he fears death.

I think were all little bit apprehensive, he says. I like to focus more on living, even with all this biohacking and all this stuff you dont know if youre going to make it to the next day.!

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Texan Spending Fortune, Hours A Day Trying To Live To At Least 120 Years Old: I Am My Asset - CBS Dallas / Fort Worth


Nov 11

Foods that flop your show in the bedroom – Jamaica Observer

BY CANDIECE KNIGHT

Monday, November 11, 2019

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SO you've gotten your oats, peanuts, roots, nutmeg and everything else that Vybz Kartel prescribed to improve your performance in the bedroom, but your cast member is still exiting the stage before the end of the first scene. Maybe it's time to take a look at not just the star-studded foods that you consume just before the show, but the other foods in your diet that have been working menacingly behind the scenes to close the curtains prematurely.

Could any of these libido killers be the culprits that are turning your bedroom romance into horror? Registered nutritionist at Nestle Jamaica, Janique Watts, recommends that you cut them from your dietary line-up before the next act if you don't want it to be over before the fat (or slim) lady sings.

Sugars

Feel like going for a round after a high-carb dinner? Think again. Watts notes that sugary foods require insulin, which is produced by the pancreas to be absorbed in the body.

The production of insulin, however, does decrease the production of testosterone which therefore decreases your sexual appetite, she warns.

Highly processed foods

The key to a turgid, lasting erection is proper blood flow to the penis. The greatest antagonists of good circulation are obesity, diabetes and hypertension, all of which can be caused by constantly consuming highly processed foods.

These foods contain high amounts of salt and saturated fats, both of which when eaten in excess can lead to weight gain and obesity. This is the precursor to developing non-communicable diseases like diabetes and hypertension. This therefore means arteries are clogged from excessive fat being stored, and this restricts the natural flow of blood. This results in decreased sexual performance, Watts explains.

Trans fats

While you cannot completely avoid some fat in your diet, and some are actually very healthy, you will do your sex life a huge favour if you stay away from trans fats which are found in many fried foods, baked goods, margarines and spreads.

Trans fats are known to negatively affect testicular function, Watts says. This is due to the male sexual organ being made up of very small veins, and with added fat in the body, blood circulation to areas farther away from the heart becomes more restricted. Less blood flow leads to poor erections.

Mint

Are we really saying you can't even have a little mint tea before she comes over? No, we're not. We're saying you should watch it though, because it was observed in a review that menthol (active ingredient in mint) lowers testosterone in women who suffer from PCOS(polycystic ovary syndrome) .

There would need to be further research done for both sexes to have a conclusive claim that testosterone levels would also be affected in men, thus leading to lowered libido, Watts says.

Soy

Got milk? Then drink it if you can, because soy the most popular dairy alternative contains phytoestrogens. These are compounds that mimic the female hormone estrogen.

High consumption of these foods lead to hormone imbalances, and this can then lead to decreased sexual desire and performance in men, Watts notes.

Alcohol

That bedroom tonic might be playing a completely different role from the one that's in the script. While you might feel a buzz after having your favourite beer or tonic wine to take the edge off before the show, it does not increase your stamina.

Alcohol is a depressant and as such will cause a loss in sexual desire and therefore affect the ability of having an erection, Watts points out. Over time, too, heavy drinking leads to lowered testosterone levels and increased oestrogen levels, which results in decreased libido.

Marijuana

While you're feeling high and floating on the clouds, your partner, who has to endure your lackluster performance, might be feeling rather low. Whether you roll one up before the act or consume edibles such as weed brownies or ganja tea to get in the mood, cannabis not only calms your nerves, but also your testosterone levels for up to 24 hours. Watts warns that prolonged use can also lead to erectile dysfunction.

Now you can read the Jamaica Observer ePaper anytime, anywhere. The Jamaica Observer ePaper is available to you at home or at work, and is the same edition as the printed copy available at http://bit.ly/epaperlive

Original post:
Foods that flop your show in the bedroom - Jamaica Observer


Nov 11

Everything you need to know about steroids – RTE.ie

Analysis: most commonly associated with cheating athletes, steroids occur naturally in our bodies and play an important role in modern medicine

By Dipali Ahuja, University of Limerick; Laurie Ryan, University of Limerick and Emer Browne, TCD

"And the winner is!" - or is it? The prevalence of doping at major sporting events such as the Olympics has called into question the rightful winner of many competitions. In the 2012 European Athletic Championships women's 1500 metres final, the first, second, third and fourth placed athletes subsequently faced bans for testing positive for using performance enhancing substances. The athlete who originally finished fifth, Nuria Fernndez, was eventually deemed the rightful winner.

The most commonly used class of performance enhancing substances are steroids. It's a word which evokes images of fallen athletes such as Lance Armstrong and Ben Johnson. However, what many people may not know is that steroids occur naturally in our bodies and play an important role in modern medicine.

From RT Radio 1'sToday with Sean O'Rourke Show, Paul Kimmage, the first toraise questions about the endemic drugs culture in cycling, on doping in rugby

Steroids are hormones produced by the body to help cells, tissues and organs function. Our body'snaturally occurring steroids are created using cholesterol as a starting material. This occurs mainly in the adrenal glands, which are located just above the kidneys.

There are two main classes of steroids: corticosteroids and androgenic steroids. Corticosteroids control many natural processes in our bodies such as responding to inflammation and regulating salt and water balance. They can be produced naturally in the body or synthetically manufactured. Sometimes the body does not produce enough corticosteroids, such as in Addison's disease, and taking synthetic steroids can be lifesaving. Similarly, steroids are often prescribed by doctors to help patients to recover from illness.

The use of corticosteroids as medicines is only possible thanks to the work of several medicinal chemists who enabled the cost-effective synthesis of cortisone. When cortisone was first synthesized in the 1940s, it required the bile of 2,500 cows as a starting material, before a complicated 36 step chemical process was applied to produce 15 milligrams of cortisone (which is onlyapproximately 0.5% of a teaspoon!).

FromRT Radio 1's Drivetime, Galway GP Dr Barry Higgins andJim O'Sullivan from theRivers Edge Gym in Cork discuss dangerous steroid use

The discovery of a new starting material, diosgenin, from the Mexican yam (a vegetable from the sweet-potato family), dramatically reduced the cost of producing cortisone and enabled its use as a medicine. Many other medicines have since been developed in the corticosteroid family including; inhalers to treat asthma, tablets for inflammatory conditions and creams to treat psoriasis.

The other major class of steroids are the androgenic steroids, also known as sex steroids. These include the female sex steroids like estrogen and progesterone and the male sex steroid testosterone. Just like the corticosteroids, androgenic steroids are produced in our bodies but sometimes we use synthetic versions of the androgenic steroids medicinally to treat a wide variety of conditions.

The combined oral contraceptive pill used by millions of women worldwide, for example,is a combination of a synthetic estrogen and a synthetic progesterone. The combination of these steroids at the right doses inhibit ovulation and thus prevent pregnancy. Interestingly, progesterone may also be used to support pregnancy during fertility treatment, but at a different dosing regimen.

From RT Radio 1's Ryan Tubridy Show, strongman James Fennelly on why he stopped using steroids

While the use of female sex steroids for medicinal purposes is widespread, the use of testosterone is more often associated with illicit use. Testosterone is known as the primary male hormone:when boys go through puberty, testosterone causes a deepening of their voice and growth of body hair. But the effect that testosterone has on increasing bone and muscle mass is often the reason why it is abused. These are known as anabolic effects, and where the term "anabolic steroid" comes from.

While testosterone is used medicinally by men who dont produce enough testosterone naturally, its abuse dates back to when it was first synthesized in 1935. During the Second World War, it was discovered that malnourished soldiers treated with artificial testosteronegained weight and displayed improved performance.

Using testosterone to improve athletic performance dates back to 1954, when the Russian weightlifting team injected themselves with testosterone prior to the World Weightlifting Championship in Vienna. Seeing the advantage this substance gave to the Russian athletes, American doctor John Ziegler returned to America and started work developing a novel anabolic steroid. This culminated in the creation of methandrostenolone, which was sold under the trade name "Dianabol". With this, the era of anabolic steroid use in sports began.

From RT 2fm's Game On, a discussion on how the huge rise in 18 to 34 year olds abusing steroids

Aware that the use of these substances was resulting in an uneven playing field, the International Olympics Committee (IOC) banned the use of performance enhancing substances in 1967. However, it wasnt until 1976 that a reliable test that could detect anabolic steroid use was developed.

Despite the reputational damage athletes faced if caught, anabolic steroid use was widespread in elite sport in the 1980s and 1990s. As well as putting their careers at risk, athletes using anabolic steroids put their health at risk. This is because prolonged, unsupervised use of anabolic steroids can result in side effects such as liver and heart disease, infertility, depression, aggression, acne and hair loss. Moreover, as anabolic steroids are commonly bought on the black market, the quality and safety tests that are required for legitimate medicines are unlikely to have been performed.

Ultimately, from a medicinal perspective, steroids are an excellent resource that have transformed modern medicine. However, the medicinal use of steroids means that you have been advised by a professional to use a specific steroid dose for a particular amount of time to treat aspecific condition. Furthermore, when you get a steroid from the pharmacist, its quality and efficacy have been tested under stringent regulations.

From RT Radio 1's News At One, RT Investigates Barry O'Kelly on theillegal trade in steroids which can lead to catastrophic health consequences for users

Problems occur when healthy individuals buy unregulated products, which are labelled as steroids, on the black market. In this scenario there is no quality assurance and no medical professional to monitor side effects. Under these conditions, steroids can be dangerous.

This doesnt appear to have stopped the influx of illegal anabolic steroids onto the Irish market, as 98,055 anabolic steroid dosage units were detained in 2018 by the Irish regulatory body for medicines, the HPRA. In light of this, there is a greater need to educate the public about the dangers of abusing steroids and how we should treat them with respect as medicines.

Dipali Ahuja is a PhD researcher with SSPC, the SFI Research Centre for Pharmaceuticals, at the University of Limerick.Laurie Ryan is a PhD researcher with SSPC at the University of Limerick.Emer Browneis a pharmacist and PhD researcher with SSPC at TCD.

The views expressed here are those of the author and do not represent or reflect the views of RT

Read more here:
Everything you need to know about steroids - RTE.ie



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