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Apr 22

Removing 2 amino acids from diet may help fight cancer – WPTZ

Removing amino acids serine and glycine from one's diet could slow the development of lymphoma and intestinal cancer, according to research from the University of Glasgow and Beatson Institute.

Scientists also found that the specialized diet "made some cancer cells more susceptible to chemicals called reactive oxygen species" when tested in mice.

Now, researchers want to set up clinical trials with cancer patients to test the safety and efficacy of the treatment.

"Our findings suggest that restricting specific amino acids through a controlled diet plan could be an additional part of treatment for some cancer patients in future, helping to make other treatments more effective," said Dr. Oliver Maddocks, a scientist at the University of Glasgow.

Chemotherapy and radiotherapy increase levels of glycine and serine in mice, so a diet restricting the two amino acids could make cancer treatments more effective.

"This is a really interesting look at how cutting off the supply of nutrients essential to cancer cell growth and division could help restrain tumors," said Dr. Emma Smith, science communication manager at the Beatson Institute. "The next steps are clinical trials in people to see if giving a specialized diet that lacks these amino acids is safe and helps slow tumor growth as seen in mice."

Link:
Removing 2 amino acids from diet may help fight cancer - WPTZ

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