Search Weight Loss Topics: |
Metabolism of l-arabinose converges with virulence regulation to promote enteric pathogen fitness – Nature.com
Caballero-Flores, G., Pickard, J. M. & Nez, G. Microbiota-mediated colonization resistance: mechanisms and regulation. Nat. Rev. Microbiol. 21, 347360 (2023).
Article CAS PubMed Google Scholar
Bamler, A. J. & Sperandio, V. Interactions between the microbiota and pathogenic bacteria in the gut. Nature 535, 8593 (2016).
Article ADS PubMed PubMed Central Google Scholar
Connolly, J. P. R., Brett Finlay, B. & Roe, A. J. From ingestion to colonization: the influence of the host environment on regulation of the LEE encoded type III secretion system in enterohaemorrhagic Escherichia coli. Front. Microbiol. 6, 568 (2015).
Article PubMed PubMed Central Google Scholar
Turner, N. C. A., Connolly, J. P. R. & Roe, A. J. Control freakssignals and cues governing the regulation of virulence in attaching and effacing pathogens. Biochem. Soc. Trans. 47, 229238 (2018).
Article PubMed PubMed Central Google Scholar
Wale, K. R., Cottam, C., Connolly, J. P. & Roe, A. J. Transcriptional and metabolic regulation of EHEC and Citrobacter rodentium pathogenesis. Curr. Opin. Microbiol. 63, 7075 (2021).
Article CAS PubMed Google Scholar
Kaper, J. B., Nataro, J. P. & Mobley, H. L. Pathogenic Escherichia coli. Nat. Rev. Microbiol. 2, 123140 (2004).
Article CAS PubMed Google Scholar
Croxen, M. A. & Finlay, B. B. Molecular mechanisms of Escherichia coli pathogenicity. Nat. Rev. Microbiol. 8, 2638 (2010).
Article CAS PubMed Google Scholar
Moon, H. W., Whipp, S. C., Argenzio, R. A., Levine, M. M. & Giannella, R. A. Attaching and effacing activities of rabbit and human enteropathogenic Escherichia coli in pig and rabbit intestines. Infect. Immun. 41, 13401351 (1983).
Article CAS PubMed PubMed Central Google Scholar
Kenny, B. et al. Enteropathogenic E. coli (EPEC) transfers its receptor for intimate adherence into mammalian cells. Cell 91, 511520 (1997).
Article CAS PubMed Google Scholar
Jerse, A. E., Yu, J., Tall, B. D. & Kaper, J. B. A genetic locus of enteropathogenic Escherichia coli necessary for the production of attaching and effacing lesions on tissue culture cells. Proc. Natl Acad. Sci. USA 87, 78397843 (1990).
Article ADS CAS PubMed PubMed Central Google Scholar
Mcdaniel, T. K., Jarvis, K. G., Donnenberg, M. S. & Kaper, J. B. A genetic locus of enterocyte effacement conserved among diverse enterobacterial pathogens. Proc. Natl Acad. Sci. USA 92, 16641668 (1995).
Article ADS CAS PubMed PubMed Central Google Scholar
Deng, W. et al. Dissecting virulence: systematic and functional analyses of a pathogenicity island. Proc. Natl Acad. Sci. USA 101, 35973602 (2004).
Article ADS CAS PubMed PubMed Central Google Scholar
Dean, P. & Kenny, B. The effector repertoire of enteropathogenic E. coli: ganging up on the host cell. Curr. Opin. Microbiol. 12, 101109 (2009).
Article CAS PubMed PubMed Central Google Scholar
Tobe, T. et al. An extensive repetoire of type III secretion effectors in Escherichia coli O157 and the role of lambdoid phages in their dissemination. Proc. Natl Acad. Sci. USA 103, 1494114946 (2006).
Article ADS CAS PubMed PubMed Central Google Scholar
Perna, N. T. et al. Genome sequence of enterohaemorrhagic Escherichia coli O157:H7. Nature 409, 529533 (2001).
Article ADS CAS PubMed Google Scholar
Wong, A. R. C. et al. Enteropathogenic and enterohaemorrhagic Escherichia coli: Even more subversive elements. Mol. Microbiol. 80, 14201438 (2011).
Article CAS PubMed Google Scholar
Collins, J. W. et al. Citrobacter rodentium: Infection, inflammation and the microbiota. Nat. Rev. Microbiol. 12, 612623 (2014).
Article CAS PubMed Google Scholar
Mullineaux-Sanders, C. et al. Citrobacter rodentiumhostmicrobiota interactions: immunity, bioenergetics and metabolism. Nat. Rev. Microbiol. 17, 701715 (2019).
Article CAS PubMed Google Scholar
Crepin, V. F., Collins, J. W., Habibzay, M. & Frankel, G. Citrobacter rodentium mouse model of bacterial infection. Nat. Protoc. 11, 18511876 (2016).
Article CAS PubMed Google Scholar
Kamada, N. et al. Regulated virulence controls the ability of a pathogen to compete with the gut microbiota. Science 336, 13251329 (2012).
Article ADS CAS PubMed PubMed Central Google Scholar
Connolly, J. P. R. et al. Host-associated niche metabolism controls enteric infection through fine-tuning the regulation of type 3 secretion. Nat. Commun. 9, 4187 (2018).
Article ADS PubMed PubMed Central Google Scholar
Njoroge, J. W., Nguyen, Y., Curtis, M. M., Moreira, C. G. & Sperandio, V. Virulence meets metabolism: Cra and KdpE gene regulation in enterohemorrhagic Escherichia coli. MBio 3, e0028000212 (2012).
Article CAS PubMed PubMed Central Google Scholar
Curtis, M. M. et al. The gut commensal bacteroides thetaiotaomicron exacerbates enteric infection through modification of the metabolic landscape. Cell Host Microbe 16, 759769 (2014).
Article CAS PubMed PubMed Central Google Scholar
Menezes-Garcia, Z., Kumar, A., Zhu, W., Winter, S. E. & Sperandio, V. L-Arginine sensing regulates virulence gene expression and disease progression in enteric pathogens. Proc. Natl Acad. Sci. USA 117, 1238712393 (2020).
Article ADS CAS PubMed PubMed Central Google Scholar
Connolly, J. P. R. et al. The host metabolite D-serine contributes to bacterial niche specificity through gene selection. ISME J. 9, 10391051 (2015).
Article CAS PubMed Google Scholar
OBoyle, N., Connolly, J. P. R., Tucker, N. P. & Roe, A. J. Genomic plasticity of pathogenic Escherichia coli mediates D-serine tolerance via multiple adaptive mechanisms. Proc. Natl Acad. Sci. USA 117, 2248422493 (2020).
Article ADS PubMed PubMed Central Google Scholar
Conway, T. & Cohen, P. S. Commensal and pathogenic Escherichia coli Metabolism in the gut. Microbiol. Spectr. 3, MBP-0006-2014 (2015).
Article Google Scholar
Fabich, A. J. et al. Comparison of carbon nutrition for pathogenic and commensal Escherichia coli strains in the mouse intestine. Infect. Immun. 76, 11431152 (2008).
Article CAS PubMed PubMed Central Google Scholar
Crozier, L. et al. The role of l-arabinose metabolism for Escherichia coli o157:H7 in edible plants. Microbiology 167, 112 (2021).
Article Google Scholar
Mayer, C. & Boos, W. Hexose/pentose and hexitol/pentitol metabolism. EcoSal Plus https://doi.org/10.1128/ecosalplus.3.4.1 (2005).
John, M. et al. Use of in vivo-induced antigen technology for identification of Escherichia coli O157:H7 proteins expressed during human infection. Infect. Immun. 73, 26652679 (2005).
Article CAS PubMed PubMed Central Google Scholar
Segura, A. et al. Transcriptomic analysis reveals specific metabolic pathways of enterohemorrhagic Escherichia coli O157:H7 in bovine digestive contents. BMC Genom. 19, 766 (2018).
Article Google Scholar
Rice, A. J., Park, A. & Pinkett, H. W. Diversity in ABC transporters: type I, II and III importers. Crit. Rev. Biochem. Mol. Biol. 49, 426437 (2014).
Article CAS PubMed PubMed Central Google Scholar
Drousiotis, K. et al. Characterization of the l-arabinofuranose-specific GafABCD ABC transporter essential for l-arabinose-dependent growth of the lignocellulose-degrading bacterium Shewanella sp. ANA-3. Microbiology 169, 3 (2023).
Article Google Scholar
Zschiedrich, C. P., Keidel, V. & Szurmant, H. Molecular mechanisms of two-component signal transduction. J. Mol. Biol. 428, 37523775 (2016).
Article CAS PubMed PubMed Central Google Scholar
Schleif, R. AraC protein, regulation of the l-arabinose operon in Escherichia coli, and the light switch mechanism of AraC action. FEMS Microbiol. Rev. 34, 779796 (2010).
Article CAS PubMed Google Scholar
Mullineaux-Sanders, C. et al. Citrobacter rodentium relies on commensals for colonization of the colonic mucosa. Cell Rep. 21, 33813389 (2017).
Article CAS PubMed PubMed Central Google Scholar
Carlson-Banning, K. M. & Sperandio, V. Catabolite and oxygen regulation of enterohemorrhagic Escherichia coli virulence. MBio 7, e0185216 (2016).
Article CAS PubMed PubMed Central Google Scholar
Freter, R., Brickner, H., Fekete, J., Vickerman, M. M. & Carey, K. E. Survival and implantation of Escherichia coli in the intestinal tract. Infect. Immun. 39, 686703 (1983).
Article CAS PubMed PubMed Central Google Scholar
Yip, A. Y. G. et al. Antibiotics promote intestinal growth of carbapenem-resistant Enterobacteriaceae by enriching nutrients and depleting microbial metabolites. Nat. Commun. 14, 5094 (2023).
Article ADS CAS PubMed PubMed Central Google Scholar
Liu, B. et al. Enterohaemorrhagic E. coli utilizes host- and microbiota-derived L-malate as a signaling molecule for intestinal colonization. Nat. Commun. 14, 7227 (2023).
Article ADS CAS PubMed PubMed Central Google Scholar
Schutte, J. B., de Jong, J., van Weerden, E. J. & Tamminga, S. Nutritional implications of l -arabinose in pigs. Br. J. Nutr. 68, 195207 (1992).
Article CAS PubMed Google Scholar
Schwalm, N. D., Townsend, G. E. & Groisman, E. A. Multiple signals govern utilization of a polysaccharide in the gut bacterium bacteroides thetaiotaomicron. MBio https://doi.org/10.1128/mbio.01342-16 (2016).
Pereira, G. V. et al. Degradation of complex arabinoxylans by human colonic Bacteroidetes. Nat. Commun. 12, 459 (2021).
Article ADS CAS PubMed PubMed Central Google Scholar
Martens, E. C. et al. Recognition and degradation of plant cell wall polysaccharides by two human gut symbionts. PLoS Biol. 9, e1001221 (2011).
Article CAS PubMed PubMed Central Google Scholar
Rogowski, A. et al. Glycan complexity dictates microbial resource allocation in the large intestine. Nat. Commun. 6, 7481 (2015).
Article ADS CAS PubMed Google Scholar
Kyle, J. L., Parker, C. T., Goudeau, D. & Brandl, M. T. Transcriptome analysis of escherichia coli O157:H7 exposed to lysates of lettuce leaves. Appl. Environ. Microbiol. 76, 13751387 (2010).
Article ADS CAS PubMed PubMed Central Google Scholar
Petty, N. K. et al. The Citrobacter rodentium genome sequence reveals convergent evolution with human pathogenic Escherichia coli. J. Bacteriol. 192, 525538 (2010).
Article CAS PubMed Google Scholar
Harper, L. et al. Staphylococcus aureus responds to the central metabolite pyruvate to regulate virulence. MBio https://doi.org/10.1128/mbio.02272-17 (2018).
Jiang, L. et al. Salmonella Typhimurium reprograms macrophage metabolism via T3SS effector SopE2 to promote intracellular replication and virulence. Nat. Commun. 12, 879 (2021).
Article ADS CAS PubMed PubMed Central Google Scholar
Wiebe, M. A. et al. Serine deamination is a new acid tolerance mechanism observed in uropathogenic Escherichia coli. MBio 13, e02963-22 (2022).
Article PubMed PubMed Central Google Scholar
Ruddle, S. J., Massis, L. M., Cutter, A. C. & Monack, D. M. Salmonella-liberated dietary L-arabinose promotes expansion in superspreaders. Cell Host Microbe 31, 405417.e5 (2023).
The rest is here:
Metabolism of l-arabinose converges with virulence regulation to promote enteric pathogen fitness - Nature.com
- Fitness - Killer 550 Rep Workout [Last Updated On: June 10th, 2011] [Originally Added On: June 10th, 2011]
- Fitness - Suicide Sweat Workout [Last Updated On: June 12th, 2011] [Originally Added On: June 12th, 2011]
- Fitness Corner - Ep.1 [Last Updated On: June 12th, 2011] [Originally Added On: June 12th, 2011]
- SPECIAL - LA Fitness Expo - Ronnie Coleman [Last Updated On: June 13th, 2011] [Originally Added On: June 13th, 2011]
- LA Fitness! [Last Updated On: June 14th, 2011] [Originally Added On: June 14th, 2011]
- Dance Dance Dance Fitness [Last Updated On: June 14th, 2011] [Originally Added On: June 14th, 2011]
- Muscle [Last Updated On: June 14th, 2011] [Originally Added On: June 14th, 2011]
- 5 Minute Tone Body, Abs Workout, Fitness Training w/ Tammy [Last Updated On: June 15th, 2011] [Originally Added On: June 15th, 2011]
- Fitness - Bootylicious Workout [Last Updated On: June 16th, 2011] [Originally Added On: June 16th, 2011]
- Zumba® Fitness Music Video feat. "Pause" by Pitbull [Last Updated On: June 16th, 2011] [Originally Added On: June 16th, 2011]
- Fitness - Hot To Trot Workout [Last Updated On: June 17th, 2011] [Originally Added On: June 17th, 2011]
- Instructional Fitness - Dumbbell Bench Press [Last Updated On: June 17th, 2011] [Originally Added On: June 17th, 2011]
- Fitness - Sexy [Last Updated On: June 17th, 2011] [Originally Added On: June 17th, 2011]
- Fitness Is SEXY FTW! [Last Updated On: June 18th, 2011] [Originally Added On: June 18th, 2011]
- Fitness - Sexy Body On Fire Workout [Last Updated On: June 19th, 2011] [Originally Added On: June 19th, 2011]
- Abs Workout how to get six pack abs [Last Updated On: June 19th, 2011] [Originally Added On: June 19th, 2011]
- Killer Abs Exercise - Pike Roll Out on Fitness Ball [Last Updated On: June 22nd, 2011] [Originally Added On: June 22nd, 2011]
- Look Cute Get Fit GloZell the Fitness Guru [Last Updated On: June 23rd, 2011] [Originally Added On: June 23rd, 2011]
- 1 Intro to Ridgeline Fitness Swiss Ball Series [Last Updated On: June 24th, 2011] [Originally Added On: June 24th, 2011]
- Rob Riches WBFF Fitness Model Contest Prep. 12 Weeks Out [Last Updated On: June 26th, 2011] [Originally Added On: June 26th, 2011]
- Zumba Fitness Basic Steps Demo [Last Updated On: June 27th, 2011] [Originally Added On: June 27th, 2011]
- Get Up fitness challenge [Last Updated On: July 1st, 2011] [Originally Added On: July 1st, 2011]
- Fitness - Sexy Beast Workout - High Intensity Interval Training [Last Updated On: July 4th, 2011] [Originally Added On: July 4th, 2011]
- Your First Circuit- David's Fitness [Last Updated On: July 5th, 2011] [Originally Added On: July 5th, 2011]
- Fitness - 600 Rep Sexier Body Workout [Last Updated On: July 10th, 2011] [Originally Added On: July 10th, 2011]
- Rob Riches WBFF Fitness Model Contest Prep. 8 Weeks Out - Legs [Last Updated On: July 11th, 2011] [Originally Added On: July 11th, 2011]
- Zumba Fitness' Beginner Steps of the Week - sponsored by Degree [Last Updated On: July 13th, 2011] [Originally Added On: July 13th, 2011]
- Fitness Corner - Ep.12 [Last Updated On: July 21st, 2011] [Originally Added On: July 21st, 2011]
- Your Shape Fitness Evolved 2012 Trailer [Last Updated On: July 22nd, 2011] [Originally Added On: July 22nd, 2011]
- Rob Riches WBFF Fitness Model Contest Prep. 10 Weeks Out - Triceps [Last Updated On: July 23rd, 2011] [Originally Added On: July 23rd, 2011]
- Rob Riches WBFF Fitness Model Contest Prep. 7 Weeks Out - Back [Last Updated On: July 25th, 2011] [Originally Added On: July 25th, 2011]
- Fitness - Rock'n No Rolls Workout [Last Updated On: July 27th, 2011] [Originally Added On: July 27th, 2011]
- Rob Riches WBFF Fitness Model Contest Prep. 5 Weeks Out - Chest [Last Updated On: August 1st, 2011] [Originally Added On: August 1st, 2011]
- Dance Fitness w/ Mia - Forget You - Cee lo AND Echa Pa' Lante - Thalia [Last Updated On: August 3rd, 2011] [Originally Added On: August 3rd, 2011]
- Owen Hargreaves in Fitness Training Offered 4 Year Contract with Brighton Electricity [Last Updated On: August 6th, 2011] [Originally Added On: August 6th, 2011]
- Back Workout @ LA Fitness Santa Monica California [Last Updated On: August 13th, 2011] [Originally Added On: August 13th, 2011]
- Bennett Streets on The Body Shop on FTNS Fitness Radio [Last Updated On: August 15th, 2011] [Originally Added On: August 15th, 2011]
- Akward Trainer "Pole Fitness" [Last Updated On: August 16th, 2011] [Originally Added On: August 16th, 2011]
- Joe "The Beast" DeRousie [Last Updated On: August 16th, 2011] [Originally Added On: August 16th, 2011]
- Aqua Fit Exercise Class at LA Fitness [Last Updated On: August 17th, 2011] [Originally Added On: August 17th, 2011]
- Start/Select - Diablo III, SoulCalibur V and Zumba Fitness [Last Updated On: August 17th, 2011] [Originally Added On: August 17th, 2011]
- Fitness Diet for Students [Last Updated On: August 21st, 2011] [Originally Added On: August 21st, 2011]
- Health@Google: Steve Kamb on "Nerd Fitness" [Last Updated On: August 21st, 2011] [Originally Added On: August 21st, 2011]
- 13 Minute Fitness Meal [Last Updated On: August 22nd, 2011] [Originally Added On: August 22nd, 2011]
- P90X Extreme Home Fitness Review [Last Updated On: August 25th, 2011] [Originally Added On: August 25th, 2011]
- Anna 'fitness' baffles everyone, Even MP Lalu Prasad Yadav [Last Updated On: August 31st, 2011] [Originally Added On: August 31st, 2011]
- GSP Fan Fitness Challenge: Fingertip Push-up [Last Updated On: September 3rd, 2011] [Originally Added On: September 3rd, 2011]
- Dance, Dance, Dance Music Video - Zumba Fitness [Last Updated On: September 8th, 2011] [Originally Added On: September 8th, 2011]
- Fitness - Tight Summer Booty Workout [Last Updated On: September 9th, 2011] [Originally Added On: September 9th, 2011]
- Day 22 of the 40 Day Fitness Challenge w/ Sawyer Hartman [Last Updated On: September 13th, 2011] [Originally Added On: September 13th, 2011]
- Zumba Fitness - E3 2010: Dancing Woman Debut Trailer | HD [Last Updated On: September 21st, 2011] [Originally Added On: September 21st, 2011]
- Fitness - Extreme Workout Challenge 2 [Last Updated On: September 23rd, 2011] [Originally Added On: September 23rd, 2011]
- Fitness - Gamerfit - Big C works out with Adrian Crowe [Last Updated On: September 24th, 2011] [Originally Added On: September 24th, 2011]
- Fitness - Fast Death Workout [Last Updated On: September 27th, 2011] [Originally Added On: September 27th, 2011]
- Zumba Fitness at Nickelodeon's World Wide Day of Play [Last Updated On: October 1st, 2011] [Originally Added On: October 1st, 2011]
- Fitness - Lower Body Workout 1: Squat Exercises [Last Updated On: October 2nd, 2011] [Originally Added On: October 2nd, 2011]
- Fitness - GaGa for Tight Buns Workout [Last Updated On: October 3rd, 2011] [Originally Added On: October 3rd, 2011]
- Fitness - Hard Body Workout [Last Updated On: October 4th, 2011] [Originally Added On: October 4th, 2011]
- Fitness - 15 Minute Extreme Workout [Last Updated On: October 4th, 2011] [Originally Added On: October 4th, 2011]
- SELF Fitness - Dive in! [Last Updated On: October 4th, 2011] [Originally Added On: October 4th, 2011]
- Fitness - Sexy Torture Workout [Last Updated On: October 4th, 2011] [Originally Added On: October 4th, 2011]
- Meital Dohan Fitness Wisdom [Last Updated On: October 4th, 2011] [Originally Added On: October 4th, 2011]
- Stoke v Liverpool - Dalglish on Bellamy and Andy Carroll fitness | English Premier League 2011 [Last Updated On: October 5th, 2011] [Originally Added On: October 5th, 2011]
- Flat-Belly Foods (Diet [Last Updated On: October 5th, 2011] [Originally Added On: October 5th, 2011]
- Beware of Fitness myths [Last Updated On: October 5th, 2011] [Originally Added On: October 5th, 2011]
- Laugh your way to fitness [Last Updated On: October 5th, 2011] [Originally Added On: October 5th, 2011]
- Female Fitness Model Training For Chest, Biceps, Triceps [Last Updated On: October 5th, 2011] [Originally Added On: October 5th, 2011]
- Day 40 of the 40 Day Fitness Challenge w/ Sawyer Hartman [Last Updated On: October 5th, 2011] [Originally Added On: October 5th, 2011]
- Fitness - Boot Camp Workout 1: Burpee's Exercise [Last Updated On: October 6th, 2011] [Originally Added On: October 6th, 2011]
- Fitness - Sexy Monkey Workout [Last Updated On: October 6th, 2011] [Originally Added On: October 6th, 2011]
- FITNESS Trainer! [Last Updated On: October 8th, 2011] [Originally Added On: October 8th, 2011]
- Fitness - Abs Core Cardio Workout [Last Updated On: October 9th, 2011] [Originally Added On: October 9th, 2011]
- How to do Fitness? (Part 2) [Last Updated On: October 11th, 2011] [Originally Added On: October 11th, 2011]
- Health and Fitness Special - TWiST #192 [Last Updated On: October 11th, 2011] [Originally Added On: October 11th, 2011]
- Zumba Fitness 2, the video game: Behind the Scenes [Last Updated On: October 11th, 2011] [Originally Added On: October 11th, 2011]
- Makeup, Fashion [Last Updated On: October 11th, 2011] [Originally Added On: October 11th, 2011]
- 24 Hour Fitness Tip: Try Different Cardio Machines [Last Updated On: October 11th, 2011] [Originally Added On: October 11th, 2011]
- How to do Fitness? (part 1) [Last Updated On: October 11th, 2011] [Originally Added On: October 11th, 2011]
- On the Go Fitness Snack: Homemade Trail Mix [Last Updated On: October 11th, 2011] [Originally Added On: October 11th, 2011]
- Bradley Cooper's Total-Body Workout (Diet [Last Updated On: October 11th, 2011] [Originally Added On: October 11th, 2011]