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Oprah Winfrey said she takes her last meal at 4 pm.

Celebrity talk show host Oprah Winfrey recently revealed that she takes weight-loss medication to help manage her weight. In an interview with People, Winfrey, who turns 70 next month, explained how she battled body-shaming and body image issues in all the decades she has been in the public eye. She said that she's over with the shame that comes with admitting that she uses these pharmaceutical aids. "I now use it as I feel I need it, as a tool to manage not yo-yoing," she told the publication.

"I'm absolutely done with the shaming from other people and particularly myself," the 69-year-old told People. "The fact that there's a medically approved prescription for managing weight and staying healthier, in my lifetime, feels like relief, like redemption, like a gift, and not something to hide behind and once again be ridiculed for," she continued.

Further, the global influencer revealed that a turning point in her weight-loss journey was knee surgery in 2021 after which she started to make stricter efforts to maintain a healthier lifestyle. "After knee surgery, I started hiking and setting new distance goals each week. I could eventually hike three to five miles every day and a 10-mile straight-up hike on weekends," she told the outlet, adding, "I felt stronger, more fit and more alive than I'd felt in years".

"I eat my last meal at 4 o'clock, drink a gallon of water a day, and use the WeightWatchers principles of counting points. I had an awareness of (weight-loss) medications but felt I had to prove I had the willpower to do it. I now no longer feel that way," the talk show host said.

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Although Winfrey did not reveal the drug she takes, she said that her approach to using pharmaceutical aids came in July during a taped panel conversation with weight loss experts and clinicians. "I had the biggest aha along with many people in that audience," Winfrey said, adding that she had been blaming herself for being overweight without realising that she had a predisposition "that no amount of willpower is going to control".

Overall, Oprah Winfrey said that her weight loss and fitness progress have allowed her to lead a "more vital and vibrant life". "In Hawaii, I live on a mountain, and there's this big hill - I used to look out the window every morning and say, 'God, one day I want to walk up that mountain.' Last year over Christmas I did it...It felt like redemption," she added.

Notably, Winfrey's revelation comes amid a time when there has been a buzz around weight-loss drugs like Ozempic and Wegovy. The medication reportedly regulates hunger signals and allows people to feel full while eating less. However, experts have noted that the drug also has side effects such as nausea, diarrhoea and constipation.

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"Done With Shaming": Oprah Winfrey Admits To Using Weight-Loss Medication - NDTV

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Oprah Winfrey recently admitted to using a weight-loss medication to maintain her weight after fans speculated that the media mogul was using Ozempic, which is a popular drug often used by celebrities.

Winfrey struggled with her weight throughout the two-decade-plus run of her syndicated talk show, The Oprah Winfrey Show and became the butt of numerous cruel jokes by comedians on late-night television.

The former talk show host was previously slammed for shaming weight loss drugs and calling them the easy way out. But now shes opening up about her weight-loss journey, and she feels relieved that a weight-loss drug now exists to help people lose and maintain their weight.

It was public sport to make fun of me for 25 years. I have been blamed and shamed, and I blamed and shamed myself, Winfrey said in a interview with People magazine published this week. I was on the cover of some magazine and it said, Dumpy, Frumpy and Downright Lumpy. I didnt feel angry. I felt sad. I felt hurt. I swallowed the shame. I accepted that it was my fault.

Although Winfrey admitted to using a weight-loss drug, she did not specify which one. Ozempic, Wegovy and Mounjaro are the three of the most popular drugs people are currently using for weight loss. Wegovyis the only one approved for weight loss while Ozempic and Mounjaro were created totreat diabetes but patients also found them effective for losing weight.

I now use it as I feel I need it, as a tool to manage not yo-yoing, she continued. The fact that theres a medically approved prescription for managing weight and staying healthier, in my lifetime, feels like relief, like redemption, like a gift, and not something to hide behind and once again be ridiculed for. Im absolutely done with the shaming from other people and particularly myself.

The 69-year-olds latest weight-loss journey began after having knee surgery back in 2021 and she began hiking. She also had an aha moment during a taping of Oprah DailysThe Life You Want series last July. Winfreys panel included weight loss experts and clinicians for an episode titled The State of Weight as she learned about weight-loss prescription drugs.

I realized Id been blaming myself all these years for being overweight, and I have a predisposition that no amount of willpower is going to control, she said. Obesity is a disease. Its not about willpower its about the brain.

After Winfrey lost 67 pounds by starving herself on a liquid diet in 1988, she brought out a wagon of fat during an episode of The Oprah Winfrey Show to show viewers how much extra weight shed been carrying on her frame.

She had weighed more than 200 pounds at the time and whittled herself down on the Optifast diet, which enabled her to get into her old size 10 in Calvin Klein jeans. Unfortunately, she gained the weight back and has continued to struggle with her weight throughout her career.

Winfrey now incorporates exercise into her routine and can hike several miles per day. She also drinks one gallon of water daily and uses a WeightWatchers-style approach of counting points. I felt stronger, more fit and more alive than Id felt in years, she said of her exercise routine.

Winfrey is only a few pounds away from her goal of 160 pounds and noted that the prescription weight-loss drug isnt a magic solution for her and stresses the importance of healthy living. The Color Purple producer also noted that the drug helped her to only gain a half-pound over Thanksgiving as opposed to gaining eight pounds like I did last year.

Its everything, she said. I know everybody thought I was on it, but I worked so damn hard. I know that if Im not also working out and vigilant about all the other things, it doesnt work for me.

Fans reacted on social media, and most didnt seem upset that Winfrey is using a prescription drug to maintain her weight after seeing her struggle for so many years.

One fan wrote, Oprah is on Ozempic and still found a way to push weight watcher points. She gone find some way to bring press to her businesses. Shes a true entrepreneur lol. Another fan replied, Were people really surprised that Oprah is on Ozempic? Oprah been trying to lose weight since I was a kid. And Im 40!

Winfrey has served as an ambassador for Weight Watchers since 2015. She also serves as a board member and adviser and owns 10 percent of the company.

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Oprah Winfrey Ends the Shaming and Confesses to Using Weight-Loss Medication Following Fans' Speculation She's ... - Atlanta Black Star

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When you think of all the diet schemes promoted every January, its clear theyre doing more harm than good.

The January dieting culture is incredibly detrimental to mental health, Attwood says. Diets are set up to fail, so people are left feeling as though they are the failure, when in fact the diet and wellness industries make money off of the unsustainable nature of intentional weight-loss, creating a cycle of guilt, shame, and blame that distracts us all from fully showing up in our lives and pursuing things that are truly meaningful to us.

Diets are set up to fail, so people are left feeling as though they are the failure.

If breaking this cycle sounds too intimidating, I have good news: Youve already started. Not only are you choosing to read this story, but youre in the right place to continue the work: online.

There is ample research establishing a link between social media use and body dissatisfaction, eating concerns, anxiety, depression, and drive for thinness, but at the same time, social media can serve as a mental health resource when used mindfully and consumed critically, Dr. DeCaro explains. So no, you dont have to become a digital nomad to tune out all the noise.

As an alternative, Dr. DeCaro suggests unfollowing anyone posting information or advice about food who isnt a registered, size-inclusive, anti-diet dietician, and blocking accounts that negatively impact your mood or increase the urge to engage in harmful behaviors, such as restricting or overexercising. Certain social media sites have underutilized features built into the platform that could be helpful for some, such as setting a limit on TikTok screen time, and turning on restricted mode can reduce some triggering content, she says.

If our happiness is tied to our body size, we will forever be chasing an elusive target.

Thats why Attwood recommends filling your feed with people of all body sizes who encourage you to eat for joy and pleasure: I always tell clients to trust their gut instinct about someone they follow on social media. If it makes them feel a less than positive emotion, they dont need a reason or explanation. Just hit unfollow. Your gut reaction is reason enough.

If digital tools arent providing adequate reprieve from triggering content, Onysko suggests limiting time on social media in general throughout the month of January, or taking a break indefinitely.

Another pro tip? Try to reframe how you think of self-improvement. The biggest focus should be on how you want tofeel, not on how you want to look, Onysko says. Dr. DeCaro agrees: Shift your mental energy to your core values instead of your appearance. Create goals to live a life more aligned with those values. When you take the time to identify what is truly important to you, chances are the size of your clothes wont matter as much as you thought it did.

Our bodies are meant to change, and will continue to change throughout our lives.

For example, if one of your New Years resolutions is to incorporate more movement into your daily routine, be sure to disassociate the activity from weight loss or body size. When we take the focus off of changing our body with a workout, that small mental shift can improve our relationship with movement and with ourselves. Exercise shouldn't feel like a punishment, Dr. DeCaro says.

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New Year's Resolution Diets Don't WorkWhy Do We Keep Trying to Make Them Happen? - Glamour

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The first global declaration on curbing emissions from food production agreed during week one of COP28 is a start, say researchers.However, one must acknowledge that the declaration avoids addressing some of the most contentious issues in the realm of emissions reduction.

More than 130 countries have signed the COP28 UAE Declaration on Sustainable Agriculture,Resilient Food Systems, and Climate Action, a declaration pledging to reduce greenhouse gas emissions from processes related to producing and consuming food. These countries represent 5.7 billion people and 75% of all emissions from global food production and consumption, according to this years host, the United Arab Emirates (UAE). The agreement marks a historic moment in the nearly three-decade history of climate summits, as it is the first time that the importance of food systems is formally recognised.

Food production and consumption contribute substantially to greenhouse gas emissions, constituting approximately one-third of the global emissions, with meat and dairy accounting for emissions but providing just 18% of the worlds calories. Meat and dairy production are also leading causes of other environmental ills, including deforestation, pandemic risk, and water pollution. Plant-based foods typically have a much smaller carbon footprint, and require far less land and water.

The declaration has garnered widespread approval. Its great to finally have food on the COP menu, said Clement Metivier, a climate and biodiversity policy expert at the World Wildlife Fund (WWF) for Nature in the UK. There is really a growing momentum around food systems transformation to tackle both the biodiversity and climate crisis.

However, the declaration has faced scrutiny from food experts, including the International Panel of Experts on Sustainable Food Systems, due to the lack of specific targets or explicit measures to tackle sustainable diets.

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The declaration, signed on December 1st, 2023 acknowledges the pivotal role of agriculture and food systems in both contributing to and mitigating climate change. It recognises the significant threats to food availability, particularly for vulnerable communities, and delineates goals to transition to lower-emissions diets, bolster resilience, enhance food security, and advocate for the well-being of marginalised workers.

By signing the Declaration, signatories committed to incorporating food and agriculture into their upcoming rounds of emissions reduction plans, commonly referred to as Nationally Determined Contributions (NDCs), demonstrating their commitment to achieving the objectives of the Paris Agreement. But its initial impact looks likely to be limited.

Notably, the declaration lacks legal binding, and it overlooks the significant role of fossil fuels within food systems, such as the use of transportation, farm machinery, and refrigeration. Furthermore, the latest draft text, crucial for all nations to endorse at the conclusion of COP28, does not address food systems. It was a glaring omission, said Metivier, who raised hopes for rectification in the final version.

Its at least a commitment at the highest level, but theres still not much specificity in terms of what actually needs to be done, said biodiversity and agriculture researcher Lim Li Ching at the Third World Network, a non-governmental organisation based in Malaysia. We need an inclusion of food systems and phasing out of fossil fuels to be built into the revision of national climate commitments.

We cannot meet our global climate goals without urgent action to transform the industrial food system, said Lim Li Ching, co-chair of IPES-Food and senior researcher for Third World Network. But while this is an essential first step, the language remains very vague and specific actions and measurable targets are conspicuously missing.

The resolution will only be meaningful if governments turn the promises into real policies. The 134 countries who have committed to the declaration will need to work with every actor in the food system to deliver real lasting change, says Jennifer Morris, CEO of global environmental organisation The Nature Conservancy.

Reducing emissions from agriculture is a complex task, as it involves changing farming practices, land use, and potentially altering dietary patterns. The diverse nature of agricultural systems

globally makes it challenging to find one-size-fits-all solutions that are effective across different regions and farming contexts.

For example, reducing meat consumption may be feasible for individuals in high-income countries; however, the situation is more complex in low- and middle-income nations. In these countries, meat serves as a scarce protein source for many, meaning cutting down on meat is not as achievable.

The nutritional needs of different individuals must also be taken into account. The universal healthy reference diet, created by the EATLancet Commission on Food, Planet, Health demonstrates what an ideal diet would look like that increases the likelihood of attainment of the UN Sustainable Development Goals (SDGs). It prioritises the consumption of vegetables, fruits, whole grains, and more, over red meat and processed foods. However, some researchers questioned whether the diet would provide enough nutrition for people in low-income settings.

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Implementing changes in food systems may also face resistance from powerful economic and political interests. Agricultural industries, particularly those tied to conventional and intensive farming practices, may resist changes that could impact their profitability. Transitioning to more sustainable practices might require financial investments and changes in production models that some businesses may find economically challenging.

Concerns have been raised about the influence of the meat industry, whose lobbying reportedly includes efforts to create positive livestock content at COP28. A recent Guardian investigation exposed how pressure from the meat industry led to the Food and Agriculture Organization (FAO) diluting reports and suppressing evidence of livestocks impact on the climate emergency. Notably, the COP28 declaration does not explicitly mention meat or livestock, raising questions about the industrys role in shaping climate related policies.

As the world grapples with the urgency of addressing the agricultural impact on climate change, the question lingers: Will this declaration actually work?

While it is a first-of-its-kind international agreement, the declarations vagueness, lack of specific targets, and the absence of legal binding raise concerns about its effectiveness. The complex landscape of global food systems, coupled with potential resistance from influential economic interests, particularly in the meat industry, underscores the challenges ahead. The upcoming revisions of national climate commitments provide an opportunity to rectify current shortcomings and pave the way for a more concrete and impactful approach to curbing emissions. Ultimately, its success hinges on the translation of commitments into policies and the collaboration of nations and stakeholders across the food system spectrum.

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Will the First Global Food Systems Declaration Work? - EARTH.ORG

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Florida, a state blessed with incredibly beautiful beaches and inviting weather, is not just a popular tourist destination. It's also home to a growing trend in the field of healthcareHuman Growth Hormone (HGH) therapy. In the Sunshine State, many individuals are turning to HGH therapy not only for its well-known anti-aging benefits but also for its remarkable ability to strengthen bones and joints. This article explores the role of human growth hormone therapy Florida in improving bone and joint health and how it's making a difference in the lives of many Floridians.

Understanding HGH Therapy

Human Growth Hormone (HGH) is a hormone that your body makes on its own, thanks to a special gland in the brain called the pituitary gland. This hormone is really important because it helps the body grow, repair itself, and stay healthy. But as you get older, the body makes less of this hormone. That can cause problems like weaker bones and joints.

The Impact of Aging on Bone and Joint Health

Florida, with its sizable senior population, faces significant challenges related to bone and joint health. Aging is often accompanied by conditions like osteoporosis and osteoarthritis, resulting in fragile bones and painful joints. These issues can affect mobility, independence, and overall quality of life.

HGH Therapy's Role in Strengthening Bones

One of the most promising aspects of HGH therapy is its ability to increase bone density. This benefits older individuals in Florida, where osteoporosis is a prevalent concern. HGH therapy stimulates bone growth and mineralization, making bones stronger and less susceptible to fractures.

HGH therapy can help in the healing of bone injuries and fractures. In Florida's active lifestyle, where accidents can happen, the ability to recover from bone injuries more rapidly is a significant advantage.

Enhancing Joint Health with HGH Therapy

Florida's warm climate encourages an active lifestyle, but joint problems can hinder this enjoyment. HGH therapy can also play a pivotal role in improving joint health. It stimulates collagen production, a vital component of cartilage that cushions and protects joints.

As collagen levels increase, joints become more resilient, reducing the risk of conditions like osteoarthritis. Many Floridians have found that HGH therapy allows them to continue enjoying outdoor activities like golf, tennis, and swimming well into their golden years.

Individualized Treatment Plans in Florida

One of the advantages of pursuing HGH therapy in Florida is the availability of specialized clinics that offer individualized treatment plans. These plans meet each patient's unique needs, taking into account their age, health status, and lifestyle.

Before beginning HGH therapy, patients typically undergo a comprehensive evaluation, including blood tests and a medical history review. This helps healthcare providers in Florida determine the appropriate dosage and treatment duration, ensuring optimal results while minimizing potential risks.

Safety and Monitoring

Patient safety is a top priority in Florida's HGH therapy clinics. Regular monitoring ensures the therapy is effective and safe. During the course of treatment, patients undergo periodic check-ups, including blood tests, to assess hormone levels and overall health.

Clinicians in Florida work closely with patients to monitor their progress and make necessary adjustments to their treatment plans. This personalized approach helps patients receive the maximum benefits of HGH therapy while minimizing any potential side effects.

Human growth hormone therapy in Florida is making a significant difference in the lives of those seeking to strengthen their bones and joints. With its ability to increase bone density, promote collagen production, and enhance joint health, this therapy is helping individuals maintain their mobility and independence well into their later years.

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HGH Therapy in Florida: Strengthening Bones and Joints - Yes! Weekly

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The current class of anti-obesity drugs is proving remarkably effective at removing excess pounds. However, a phase 3 randomized clinical trial led by researchers at Weill Cornell Medicine and NewYork-Presbyterian found that people who stopped taking the medication regained much of that weight within a year. At the same time, the study shows that remaining on the drug not only promotes additional weight loss but preserves improvements in metabolic and cardiovascular health.

The results from the SURMOUNT-4 study, which appeared Dec. 11 in JAMA and was sponsored by Eli Lilly and Company, demonstrated that the drug can substantially help people struggling with health issues related to their weight, but it is not a quick-fix to weight loss.

Obesity is a leading driver of many diseases that we spend our time treating in medicine; illnesses like hypertension, heart disease, diabetes and fatty liver disease are either caused by or worsened by obesity, said lead study author Dr. Louis Aronne, the Sanford I. Weill Professor of Metabolic Research and director of the Comprehensive Weight Control Center, which is part of the Division of Endocrinology, Diabetes, and Metabolism at Weill Cornell Medicine. The fact that we now have drugs that are proving to be effective is exciting and rewarding.

Tirzepatide is part of a new class of drugs called called GLP-1 receptor agonists that were developed to treat type 2 diabetes. Besides controlling blood sugar, the drugs also resulted in weight loss, so pharma companies created specific formulations to help patients shed pounds.

In 2022, a phase 3 randomized, controlled clinical trial demonstrated that tirzepatide led to a 20 percent reduction in body weight over 72 weeks. The findings prompted the U.S. Food and Drug Administration to approve the drug last month, with the trade name Zepbound, for weight loss in individuals with a body mass index (BMI) of 30 or higheror for those with a BMI of 27 or greater who also had health conditions such as high cholesterol or hypertension.

Although the initial effects were dramatic, the researchers were uncertain whether the weight loss would persist beyond the period of active treatment. To find out, they launched the SURMOUNT-4 trial, which was conducted at 70 sites in Argentina, Brazil, Taiwan and the United States between March 2021 and May 2023. The participants took a maximum tolerated dose of tirzepatide for 36 weeks, which yielded the expected weight reduction of 20.9 percent with improvements in blood pressure, blood sugar metrics and lipid levels.

Then 670 eligible participants were randomly assigned to either continue with the tirzepatide for an additional year (52 weeks) or to switch to a placebo. Those who continued on tirzepatide lost an additional 5.5 percent versus the placebo group which regained 14 percent of their weight.

Though the placebo group was still almost 10 percent lighter than their initial weight, the improvements in cardiometabolic risk factors had been reversed. Relative to placebo, tirzepatide was associated with significant improvements in BMI, lipid levels, diabetes indicators and blood pressure.

Dr. Louis Aronne

Those who went on the placebo regained about half the weight they had lost, said Dr. Aronne, who is also an internist specializing in diabetes and obesity at NewYork-Presbyterian/Weill Cornell Medical Center. Whereas those who continued on the drug lost another 5 percent, so their overall weight loss was about 25 percent.

The findings indicate that people may need to remain on tirzepatide to keep off the pounds. If you stop the medication, you regain the weight. Theres no question that will happen, said Dr. Aronne. But that shouldnt be surprising. Obesity is a chronic condition, like diabetes or high blood pressure. So, it must be treated chronically.

The researchers noted that they didnt evaluate the effects of intensive behavioral therapy on the maintenance of body weight reduction, which could make a difference in preventing weight regain after coming off the drug.

Tirzepatide works by mimicking the GLP-1 and GIP hormones that are naturally secreted by the intestine after a meal, which prompts insulin secretion. It also reduces appetite by slowing down the time it takes the stomach to empty and interacting with areas in the brain harboring GLP-1 receptors to signal satiety.

Instead of counting calories, the medicine helps a person eat less because it signals to the brain that youre full, said Dr. Aronne. The dual mechanism of action helps overcome the plateau phenomenon that is seen at some point and produces additive weight loss.

Since the drug mimics hormones that are produced in the gastrointestinal system, side effects tended to be nausea, vomiting, diarrhea or constipation and resolved with time. The study had few people dropout because of side effects.

People feel much better when they lose this kind of weight, so they are extremely enthusiastic about these treatments. But they also should realize this may require them to stay on the drug long term, said Dr. Aronne. Further studies will need to assess the long-term risks and benefits associated with these drugs, especially considering the potential for their lifelong use.

Many Weill Cornell Medicine physicians and scientists maintain relationships and collaborate with external organizations to foster scientific innovation and provide expert guidance. The institution makes these disclosures public to ensure transparency. Dr. Louis J. Aronne serves as a paid advisory board member for Eli Lilly and Company. For further information, see the profile for Dr. Louis Aronne.

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Tirzepatide Enhances Weight Loss with Sustained Treatment but Discontinuation Leads to Weight Regain - Weill Cornell Medicine Newsroom

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The Big Picture: Dr. Adriana Davis, Family Medicine, "The idea here is to know that drugs like Ozempic and Mounjaro are being used for chronic disease conditions--and you may have to take these medicines indefinitely." Doctor's Expert Insights About Weight Loss and Drugs like Tirzepatide and Ozempic in Missouri

Know this: "So, this study shows significant weight loss with tirzepatide, but highlights a challenge: stopping the drug often leads to weight regain. This isn't about willpower--it's about understanding that obesity is a chronic condition that may require ongoing medication. Like many other chronic diseases, obesity needs to be managed. It will require ongoing pharmacotherapy and lifestyle changes. This study serves as a reminder that weight management is a long-term commitment and requires sustained medical and lifestyle interventions. Also, as I've been recommending here, make sure that you know your A1C and blood cholesterol levels. Knowing these metrics will be important in guiding how you and your healthcare team treat and manage obesity." Dr. Puja Uppal, Family Medicine.

Beyond the news: These findings are creating a paradigm shift in how obesity is treated and managed--with an emphasis on long-term pharmacological intervention and lifestyle changes.

Key Findings:

"After 36 weeks of open-label maximum tolerated dose of tirzepatide (10 or 15 mg), adults (n=670) with obesity or overweight (without diabetes) experienced a mean weight reduction of 20.9%. From randomization (at week 36), those switched to placebo experienced a 14% weight regain and those continuing tirzepatide experienced an additional 5.5% weight reduction during the 52-week double-blind period." (Study Source)

Key Drivers in St. Louis County:

The study highlighted tirzepatide's efficacy in maintaining and augmenting initial weight loss in individuals who were overweight.

Participants that continued tirzepatide after an initial 36-week period experienced an additional 5.5% weight reduction of their body weight. But, those who were switched to a placebo regained an average of 14.4% of their body weight.

The study also noted improvements in cardiometabolic risk factors with tirzepatide use--this is significant for overall health outcomes.

What they're saying: "The consistency of these data across therapeutic classes spanning more than 2 decades suggests that obesity is a chronic metabolic condition similar to type 2 diabetes and hypertension requiring long-term therapy in most patients.

A notable finding in the SURMOUNT-4 trial is that after switching to placebo for 1 year, participants ended the study with substantial body weight reduction (9.9%). However, much of their initial improvement in cardiometabolic risk factors had been reversed. Further studies are needed to understand the potential long-term benefits and risks (ie, legacy effects) of such short-term therapy." (Study Source)

Health Standard Newswire: To keep the advantages gained from weight loss medications, it may be necessary to continue using them for the long term.

All of these variables above play an important role in the outcomes of your overall health.

The Health Standard Newswire.

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St. Louis Health Alert: Should I Keep Taking Tirzepatide for Weight Loss Success? Doctor Explains - Branson Tri-Lakes news

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A New Hope in Weight Loss Treatment

A recent study in the Journal of the American Medical Association has shed light on the potential of a novel therapeutic approach, tirzepatide, in managing obesity in adults. The drug, a combination of GLP-1 and glucose-dependent insulinotropic polypeptide agonism, produced synergistic effects on food intake, appetite, and metabolic function, thus facilitating significant weight loss and improved metabolic health in obese individuals.

The trial, known as SURMOUNT-4, was a randomized withdrawal study conducted across the United States, Argentina, Taiwan, and Brazil. Over the course of the study, 670 participants were randomized to continue treatment with the maximum tolerated dose of tirzepatide or receive a placebo. The results were compelling. The average percent change in weight from weeks 36 to 88 was 5.5% with tirzepatide and 14% with placebo. Furthermore, by week 88, a significantly higher percentage of tirzepatide recipients maintained at least 80% of the weight loss achieved during the lead-in period.

Continued treatment with tirzepatide was associated with significant improvements in BMI, glycated hemoglobin, fasting glucose, blood pressure, insulin, and lipid levels by week 88. These improvements in cardiometabolic risk factors underscore the potential of tirzepatide in providing holistic patient care. Beyond weight loss, the drug could have far-reaching implications for managing chronic conditions such as diabetes, hypertension, and high cholesterol levels.

The SURMOUNT-4 trials findings highlight the importance of long-term pharmacotherapy in weight management. Participants who continued to take tirzepatide lost an additional 5.5 percent of their weight, while those who switched to a placebo regained about half the weight lost. More than 90% of patients who continued taking the medication kept the weight off, while only 16.6% of those who received a placebo were able to maintain their weight loss. This emphasizes the need to treat obesity as a chronic disease, warranting long-term management strategies similar to other chronic conditions like high blood pressure.

While tirzepatide shows promise, its crucial to consider the potential side effects and long-term risks. The cost of the medication, the possible side effects, and the need for sustained medication use are all factors to weigh against the health risks associated with untreated obesity. As tirzepatide and similar medications become more prevalent, medical professionals must familiarize themselves with these drugs benefits and potential drawbacks to provide balanced, comprehensive patient care.

The SURMOUNT-4 trials findings represent a significant step forward in the management of obesity. Tirzepatides demonstrated efficacy in maintaining long-term weight loss and improving cardiometabolic health highlights its potential as a game-changing therapeutic approach. As the medical community continues to explore the long-term risks and benefits of medications like tirzepatide, patients and healthcare providers can look forward to more effective strategies in the battle against obesity.

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New Hope in Weight Loss Treatment: Tirzepatide Study Reveals Promising Results - Medriva

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Weight-inclusive health care means a focus on better health with no weight loss required.

This includes practices such as eating for overall well-being rather than for the number of calories. It may also include prioritizing activities to reduce stress, avoiding smoking, drinking less alcohol and striving to be physically active in enjoyable ways.

A weight-inclusive approach to health seeks to undo the harms caused by weight stigma.

People with larger bodies often experience weight stigma as discrimination, prejudice, negative stereotypes and judgments from others including their own doctors and other health care providers. More than 40% of U.S. adults across a range of body sizes report experiencing weight stigma in their day-to-day lives.

Avoiding this stigma is likely a major driver behind the great lengths people in the U.S. go to in order to lose weight. Market data shows that Americans spent some US$72.6 billion on weight loss products and programs in 2021. In addition, weight loss efforts start early, with nearly half of all high school students in the U.S. reporting that they have tried to lose weight.

I am a nutrition epidemiologist and registered dietitian studying the consequences of weight stigma and working to develop weight-inclusive nutrition interventions.

Initially my private practice and research approach were weight-centered. A weight-centered approach focuses on weight loss to achieve health and is widely accepted in health care settings across the world. After over a decade of work in public health nutrition, I have witnessed how, in my view, the weight-centered approach harms individuals and communities. So I have shifted to using a weight-inclusive approach in practice and research.

There is an extensive body of research and public health messaging indicating that higher body weight has links with many long-term health concerns, such as high blood pressure and Type 2 diabetes.

As a result, there is a pervasive misconception that a weight-inclusive approach disregards the patients health concerns. However, proponents of weight-inclusive care argue that a weight-inclusive approach minimizes health problems by destigmatizing weight status and promoting health equity. They also acknowledge that there are links between both higher and lower body weight and various health concerns.

The dogma that lower weight is synonymous with better health is being questioned by public health researchers and health care providers. Scientists and clinicians are calling for a paradigm shift away from a weight-centered focus on weight status and body mass index, or BMI, as indicators of health.

Advocacy groups like the Association for Size Diversity and Health have long been promoting the Health at Every Size approach. This weight-inclusive approach affirms a socially just definition of health and advocates for equitable health care regardless of weight status. More recently, the American Medical Association released a statement outlining the harms and shortcomings of using BMI as a clinical measurement.

Substantial research shows that behaviors such as stopping smoking and drinking less alcohol can prevent disease and support overall long-term health, regardless of body weight. For example, a systematic review of one clinical trial and 152 observational peer-reviewed studies reported that a diet high in nutrient-rich foods with low or moderate alcohol consumption is associated with reduced risk of death for everyone.

Another example: One of my own clients with high cholesterol said that focusing on weight loss over their lifetime had left them stuck in a cycle of weight loss and weight regain, disordered eating, inconsistent and extreme exercise habits and body image concerns. After adopting weight-inclusive practices such as eating more fiber-rich foods and being more physically active, instead of focusing on losing weight, their cholesterol levels returned to normal.

Both the weight-inclusive approach and the weight-centered approach can include diet changes, increasing physical activity and reducing stress as key components to manage and prevent diseases. However, the weight-inclusive approach works to end weight stigma and acknowledges that factors such as socioeconomic status, culture and access to food and health care collectively called the social determinants of health have huge impacts on a persons body weight, shape and size. Even if a person could adhere to strict dieting and exercise routines, there will always be structural, political and other factors affecting health and weight that the individual cant control.

Whats more, evidence indicates that people who lose weight generally dont have better long-term health and fail to keep those pounds off.

There are several things that people can look for in a weight-inclusive health care practice.

Look for health care providers who:

For additional resources on weight-inclusive care, check out the Health at Every Size Health Sheets. Consider examining your own weight bias by taking an online test focused on implicit associations around weight.

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What does weight-inclusive health care mean? A dietitian explains what some providers are doing to end weight stigma - The Conversation

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Celery is an underrated and versatile vegetable. You can dip it in hummus, spread peanut butter on it, add it to salads and smoothies, or enjoy it on its own for a satisfying, crunchy snack. Regardless of how you choose to eat celery, it makes for a nutrient-dense snack option that deserves a place in any weight loss diet plan. That's why we spoke with Destini Moody, RDN, CSSD, LD, a registered dietitian and sports dietitian with Garage Gym Reviews, who shares her expert wisdom on how eating celery can help you lose weight and keep it off.

The benefits of eating celery go far beyond weight loss. One study found that the antioxidants in celery can boost heart health by reducing high blood pressure and helping control blood sugar. Other research points out that celery has anti-inflammatory properties that can help minimize the risk of cancer, heart disease, and diabetes.

If you're curious about how celery can aid your weight loss journey, read on to learn more. And, when you're done, don't miss How Many Calories Are In a Cucumber?

Celery is nutrient-dense, meaning it packs plenty of nutritional value without a ton of calories. According to the USDA, one medium celery stalk contains approximately 23 calories. Celery also has a high water content (between 90 to 99% water) and is an excellent source of soluble and insoluble fiber, which can help fill you up and prevent overeating.

"Including celery in a weight loss diet as an ingredient in healthy recipes or just as a snack is a great way to support weight loss," states Moody.

RELATED: 9 Lazy Ways to Lose Weight All Month Long

Now that we've confirmed celery can help you shed unwanted pounds, here are five reasons why it's an excellent addition to a healthy diet, according to Moody.

Celery is a weight-loss-friendly vegetable primarily due to its incredibly low-calorie count. With almost negligible calories, it allows you to indulge in a satisfying crunch without sabotaging your weight loss efforts. This makes celery an excellent choice for those looking to shed pounds while enjoying a refreshing, guilt-free snack.

Moody tells us, "One cup of chopped celery contains a measly 16 calories, so you're very unlikely to gain weight after indulging in celery in large quantities." 6254a4d1642c605c54bf1cab17d50f1e

RELATED: 10 Best Frozen Foods To Buy at Whole Foods for Weight Loss

As a crunchy and hydrating snack, celery's natural crispiness makes it a satisfying alternative to less healthy snacks like chips or sugary treats. Including celery in your snack routine is a health-conscious choice that can support your weight loss journey.

RELATED: 10 Essential Grocery Store Buys for Weight Loss

"Due to how low in calories the vegetable is, it's a great substitute for snacks that may have been higher in calories like granola bars or potato chips," Moody explains. "Also, instead of using tortilla or pita chips as a vessel for your favorite snack dips and sauces, swapping celery is a great way to cut down on calories from snacking."

Celery's high water and fiber content bulks up meals without adding extra calories. This means you can enjoy larger portions and feel more satiated, reducing the temptation to overeat. Try including celery in salads, stir-fries, or alongside your main dishes to boost the volume of your meals and increase satiety.

"Add celery to meals like soups, stews, and salads to add more volume to your meals without adding calories," says Moody. "This will make for low-calorie yet satisfying recipes to add to your weight loss diet."

RELATED: 10 Common Nighttime Habits That Can Make You Gain Weight

Fiber helps you feel fuller longer and improves digestiontwo critical components of long-term weight loss.

"Anyone who's snacked on celery knows it's made up of tough little fibers, and these fibers don't digest quickly," Moody explains. "This is good news for those trying to lose weight as this slows gastric emptying, meaning your stomach stays fuller for longer, which stops you from overeating throughout the day."

If your health goal is to lose weight, staying hydrated is critical for success. And with its high water content, celery is a fantastic snack option for those looking to shed some extra pounds.

"Studies have shown that the body [can mistake] thirst for hunger so staying hydrated is paramount when you're trying to manage your weight," says Moody. "High-water veggies like celery can help hydrate you and satisfy your hunger at the same time."

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