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How Stone Age humans unlocked the glucose in plants – Horizon magazine
Plants rich in starch helped early humans to thrive even at the height of the last Ice Age, researchers say.
While the evidence around meat eating is clear, the role of plant foods is less understood. Animal bones can last millions of years and still show cuts made by human butchering tools, whereas almost all plant remains disintegrate.
But new studies into the remains of plants that do exist are uncovering why and how our ancestors ate them.
Plants were the staples. They were the foods that formed the basis of our calories in most environments, said Dr Amanda Henry, a paleobiologist and associate professor at Leiden University in the Netherlands.
Tubers and cereals are full of starch making them good sources of glucose, which is important for brain growth as well as energy, says DrHenry. She leads a project called HARVESTwhich is studying the diets of early human species and the role of plants as food. Tubers are organs where plants store nutrients modern examples include potatoes and yams.
Some of the earliest evidence she found of eating tubers and cereals dates back 40,000 years, to the Paleolithic era. Neanderthal remains discovered in caves in Iraq and Belgium show that our cousins likely ate water lily tubers, and grains from relatives of wheat and barley grasses.
Innovation
But unlocking the energy in them required innovation. The grains may have been eaten green when they are easier to digest, but many tubers are toxic raw, says Dr Henry.
They are likely to have cooked them, said DrHenry. This not only releases energy but also makes tubers safe to eat.
(Weve found) evidence of heating food in the presence of water which suggests they were boiling them, said DrHenry. Changes in the starch granules which suggests this type of cooking were found on the dental calculus (tartar).
The Neanderthal remains indicate they ate a wide variety of plant foods. This throws doubt on a theory that they died out because they had a narrower diet than our direct ancestors, DrHenry says.
Other researchers have found earlier evidence of cooked tubers from South Africa in a fireplace dating back more than 100,000 years.
During the last glacial period when ice caps expanded to cover much of northern Europe, there was an explosion of a new technology driven by the need for processing new sources of plant food: the ground stone.
It was a major evolutionary success, dating back about 30,000 years, says Dr Emanuela Cristiani, associate professor in prehistoric archaeology at Sapienza University of Rome, Italy.
Hunter-gatherers primarily used knapped tools, made from big pieces of stone, says DrCristiani. At a certain point another technology appears like a boom which is the ground stone technology (It was) not used to cut or scrape or pierce, but to grind material, she said.
It means people were looking for new ways to eat during this dramatic climatic period, she said.
A lot of Paleo diets talk about health, but by this they mean weight loss. And I cant think of a single human ancestor who wanted to lose weight.
Amanda Henry, Leiden University, the Netherlands
Through a project called HIDDEN FOODS, DrCristiani is studying diets of humans in southeastern Europe from the late Paleolithic era when they were hunter-gathers to the Neolithic era, when there is the first evidence of farming in the region about 8,500 years ago. She is also exploring the evolution of plant food processing technologies.
Flour
Grinding meant people could make flour, which is another way of unlocking the energy in plants. The team found evidence in ground stones and plant remains in dental calculus that hunter-gatherers in the central Balkans ate a lot of wild oats, legumes and acorn flour, says DrCristiani.
The earliest evidence of flour dates back 30,000 years and was found in Russia, the Czech Republic and Italy.
It is likely that hunter-gatherers at the team's Italian research site ate cattail plants, which are abundant in a nearby river.
We think they used mostly roots. The plants root is very rich in starch and once its dried, you can make it into flour, said DrCristiani. The flour makes a sweet-tasting bread, she adds.
Paleolithic
The average Paleolithic person who survived infancy seems to have lived to age 50 or 60. It wasnt a life of luxury, it was probably a lot of work and generally cold, requiring quite a bit of effort, said DrHenry.
These early humans are likely to have died primarily from a combination of infections, parasites and physical trauma, she says.
Once people started settling and rearing animals and crops, disease levels rose mainly because they jumped from animals to humans and life expectancy appears to have fallen. That being said, agriculture is associated with increase in population size. Youre not living as long, but youre having more kids, said DrHenry.
Today, some people seeking a healthy alternative to modern industrialised diets look to the eating styles of our hunter-gatherer ancestors for inspiration.
The so-called Paleo diet eschews cereals, recommends few carbs and promotes meat and vegetables. But archaeologists say it does not represent the full diet of hunter-gatherers who ate cereals and relied on carbohydrates.
HIDDEN FOODS researchers found remains of legumes, oats and acorns in 10,000-year-old teeth from the last hunter-gatherer groups who built villages along the Danube river. This shows our idea of a Paleo diet as primarily based on protein intake is completely wrong, said DrCristiani.
Its important to understand for real what the (ancient) Paleolithic diet was. It was a very balanced way of eating, she said.
Hunter-gatherers were looking for calories, so carbohydrates in tubers and cereals would have been important.
A lot of Paleo diets talk about health, but by this they mean weight loss. And I cant think of a single human ancestor who wanted to lose weight, said DrHenry.
Diversity was integral to peoples diets, as was their ability to move to new regions. Plant foods vary a lot between environments. So, every time a human went to a new place, they had to learn what was edible, what was going to kill them and what was medicine, she said. There is no one size fits all diet. Anyone who tells you differently is trying to sell you something.
The research in this article was funded by the EU's European Research Council. If you liked this article, please consider sharing it on social media.
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How Stone Age humans unlocked the glucose in plants - Horizon magazine
Singer Park Bo Ram reveals the extreme diet method she used to lose 32 kilograms (~70 pounds) – allkpop
Singer Park Bo Ram revealed the extremediet method she used to lose a whopping 32 kilograms (~70 pounds).
She appeared on the March 26th broadcast of SBS Power FM's 'Cultwo Show' where she talked about her 2014 hit single featuring Zico "Beautiful (I Became Pretty)". She stated that she wrote the song because she too wanted to "hear that I hadbecome prettier". She also talked about how shed so much weight.
Park Bo Ram revealed that in the past, she had lost 32 kilograms (70 pounds) while eating five meals a day, with each meal consisting of half a banana and one egg. She said it was difficult but she endured it.Park Bo Ram added adisclaimer, saying that this method wasn't healthy and "It's not ok to eat like this. You're not going to have any energy."
What do you think of this extreme diet routine?
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Singer Park Bo Ram reveals the extreme diet method she used to lose 32 kilograms (~70 pounds) - allkpop
Kiwi Fruit Health Benefits: Adding This Fruit To Your Diet Can Help You Boost Digestion, Heart Health, Immunity And Much More – NDTV News
Kiwi Heath Benefits: This small fruit can offer you several health benefits
Kiwi is a small fruit loaded with several health benefits and flavours. It is a bright green coloured fruit that contains several vitamins and minerals. It is usually consumed raw which can also help you enjoy the nutritional value it offers. Kiwi is also used as an ingredient in many foods and drink in some places. From skin to digestion, it can offer you some amazing health benefits. It also has small edible black seeds. You can also prepare shakes and smoothies with this wonder fruit. Read on to know some notable health benefits of adding kiwi to your diet.
Kiwi fruit is loaded with fibre which ensures better digestion. It also contains actinidin which is a proteolytic enzyme that helps in breaking down protein. High fibre content can also prevent constipation.
High fibre content of kiwi can help you fight digestive issuesPhoto Credit: iStock
This fruit is also good for your skin. It is loaded with vitamin C which is one of the best vitamins which work wonders for your skin. Adding kiwi to your diet can help you boost skin health as well. Vitamin C helps in repairing skin and also keeps it hydrated.
Also read:Skin Care: 5 Anti-Ageing Foods For A Younger-Looking Skin
Another health benefit of adding kiwi to your diet is better sleep. A study conducted in 2011 has highlighted the effect of kiwifruit on sleep quality. It has shown positive results in those with sleep problems.
Also read:Can't Sleep At Night? Find Out If You Have Insomnia
4. Boosts heart health
Kiwi fruit is also good for your heart health. It contains anti-inflammatory properties, fibre and potassium which can boost heart health. It also controls factors that put you at a high risk of heart diseases like bad cholesterol levels and high blood pressure.
Kiwi fruit can also help you fight high blood pressurePhoto Credit: iStock
Presence of antioxidants and vitamin C can also help in asthma treatment. Adding fresh kiwi to diet is beneficial for asthma patients.
Vitamin C helps you boost immunity. It is suggested to add more foods loaded with vitamin C to your diet for better immunity.
Also read:Boost Your Immunity With These Amazing Sources Of Vitamin C; Know Other Health Benefit Of Vitamin C
Disclaimer: This content including advice provides generic information only. It is in no way a substitute for qualified medical opinion. Always consult a specialist or your own doctor for more information. NDTV does not claim responsibility for this information.
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Kiwi Fruit Health Benefits: Adding This Fruit To Your Diet Can Help You Boost Digestion, Heart Health, Immunity And Much More - NDTV News
Plant-Based Diet Is Not The Same As Vegan Diet, Key Differences You Must Know! – NDTV Food
As more and more people are cutting down meat from their diet, the interest in plant-based diet is on an all-time high. Your favourite stars are turning vegetarian, 70 percent of Oscar's after-party menu of vegan, the Golden Globes also decided to reduce the amount of meat and poultry this year in its after-party. While what you eat is completely your choice, but it is important to know about your diet fully well. Many a times people confuse terms like plant-based diet, vegetarian diet and vegan diet, and even use them interchangeably while talking. But there are stark differences betweeneach of these that you should be aware of before making the switch.
(Also Read:11 Vegetarian Recipes That Leave You Wanting More | Popular Vegetarian Recipes)
Contrary to popular perception, not all people who follow a plant-based diet eat only broccoli, kale and spinach for breakfast, lunch and dinner. Some people include a small quantum of animal-based products in their diet too, but stick mostly to eating plant-based foods. Vegans, on the other hand, rule out all animal products from their diet. Additionally, vegans also tend to shape their lifestyle in a way to avoid animal cruelty and suffering at all costs. In other words, vegans could be apprehensive buying leather, or beauty products that are made by harming animals. Vegans are also wary of the adverse environmental effects of animal products.
(Also Read:7 Things You Should Know Before Switching to Veganism)
In the United States, the plant-based food industry saw a $3.3 billion sales increase in 2018 alone. So the next time you are thinking about your diet, and the ratio of food on your plate- make sure you are well-versed with the facts.
(This content including advice provides generic information only. It is in no way a substitute for qualified medical opinion. Always consult a specialist or your own doctor for more information. NDTV does not claim responsibility for this information.)
About Sushmita SenguptaSharing a strong penchant for food, Sushmita loves all things good, cheesy and greasy. Her other favourite pastime activities other than discussing food includes, reading, watching movies and binge-watching TV shows.
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Plant-Based Diet Is Not The Same As Vegan Diet, Key Differences You Must Know! - NDTV Food
#COVID19: Diet to release stress and anxiety in lockdown days – BOL News
#COVID19 pandemic has reached in more than 160 countries and people are facing lockdown to prevent life losses, in the scenario stress level is being increased and people need some specific diets to combat stress and anxiety.
BOL NEWS consults Dr. Addiya Wahaj she is nutrition by profession and working with Pakistans consulate in Saudi Arabia nowadays.
According to nutrition, food that contains vitamin C and zinc is the best source to manage stress levels these days.
She also reveals that vitamin C is also the best source of boosting the human immune system, which is the most necessary thing in the human body to prevent novel coronavirus.
Strawberries, blueberries, hand full of cashew nut, and green vegetables are best in relieving the stress of lockdown and the pandemic.
She advises people to intake some supplements that contain zinc as zinc is the rapid stress reliever and save from anxiety.
Here she shares a picture of hearty & healthy broccoli, mushroom n cheese omelet.
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#COVID19: Diet to release stress and anxiety in lockdown days - BOL News
Testosterone Replacement Therapy Market: Rise in Geriatric Population with High Risk of Testosterone Deficiency Boost Market Growth – BioSpace
Transparency Market Research (TMR)has published a new report titled, Testosterone Replacement Therapy Market - Global Industry Analysis, Size, Share, Growth, Trends, and Forecast, 20192027.According to the report, the globalTestosterone Replacement Therapy marketwas valued atUS$ 1,613.7 Mnin2018and is projected to expand at a CAGR of4.4%from2019to2027.
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Growing Awareness about Testosterone Replacement Therapy to Drive Market
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North America to Dominate Global Market
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Testosterone Replacement Therapy Market: Rise in Geriatric Population with High Risk of Testosterone Deficiency Boost Market Growth - BioSpace
Advanced Age Management Offer Testosterone Replacement Therapy – The News Front
Advanced Age Management offers Testosterone Replacement Therapy. This mens clinic is located near Cleveland, OH, and it gives men the perfect solution if they are feeling sluggish, low energy, gaining weight, or they have a decreased sex drive. Advanced Age Management says if youre over the age of 35, you could have low testosterone, and this is normal as you get older, but you will start to notice issues more and more as you age.
This mens clinic in Cleveland, OH, says it is due to a condition called Hypergonadism, yet, they want to reassure individuals who may be concerned and worried that their testosterone production level is low, that is why they are now offering testosterone replacement therapy in their clinic. If you are suffering from one of the issues mentioned above, definitely consider scheduling an appointment with your doctor and get your testosterone levels checked. Contact Advanced Age Management, and they will advise you on your next step and get you in for a free testosterone assessment.
At Advanced Age Management, their goal is to help men build up their testosterone levels by testing testosterone levels and creating a treatment plan to get the testosterone levels back to an appropriate level so that each individual does not have to suffer anymore and can carry on with their life. This is all done through the testosterone replacement therapy at their mens clinic.
It would be best if you got in touch with Dr. John Kocka at Advanced Age Management, a low testosterone expert who carries out a series of assessments and testosterone replacement therapy for men and women in and around Cleveland Ohio. According to Advanced Age Management, the cost of the testosterone replacement therapy varies from each patient to the next, as each person will require a different treatment plan. You can, however, schedule a free consultation and also review your financial information with Dr. John Kocka once you get in touch.
Advanced Age Management emphasizes that the therapy offered to men is only for those with testosterone deficiencies, which is why this mens clinic is the best to consult with if you have found out that you have low testosterone. If needed, Dr.Kocka can offer you a same-day consultation.
If you have been given the go-ahead for testosterone replacement therapy, Advanced Age Management assures you that there are many benefits of testosterone treatment. There is evidence to suggest the therapy can improve your cardiovascular health by removing cholesterol from your arteries, a common issue that many men suffer with as they get older.
The mens clinic in Cleveland, OH, assists men for other hormone treatments as well, such as DHEA, cortisol, thyroid, natural growth hormone, insulin, and more.
Contact Advanced Age Management today at (330) 439-6591 and schedule your free consultation with one of their low testosterone doctors. This mens clinic is offering you the chance to increase your testosterone levels and, in turn, improve your health and overall well-being. At Advanced Age Management, the doctors use injection therapy for men who need more testosterone production. You can read more about low testosterone and the testosterone replacement therapy on their website at https://www.lowtohio.com.
Source:https://thenewsfront.com/advanced-age-management-offer-testosterone-replacement-therapy/
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Advanced Age Management Offer Testosterone Replacement Therapy - The News Front
Keidel: Baseball Is Our Bedrock In This Rocky World – WFAN
If life is a road, then we look for exciting or comforting mile markers every year.
Here, in the Big Apple, we circle baseball's opening day as a portal into April, when spring waves its wand over the Northeast, when we can put the cold, snow, and slush in our rearview mirror. Instead of scowling at trucks plowing a wall of muck against your car, you see trees popping with flora. Instead of grim forecasts of frigid weather, you pour over projected starters, run lines, or fantasy lineups. Instead of heavy coats and wool hats, you're ready for baseball caps and leather gloves.
Today was supposed to be that day, the first day of baseball, when we put down shovels and picked up bats, when the monotone of the weatherman is replaced by the wisdom of Keith Hernandez or Ron Darling or David Cone, breaking down balls and strikes, batters and pitchers, for the next six months.
If we are creatures of routine, then there's nothing routine about the sports landscape in general, or Major League Baseball in particular. Right now, the owners and players are trying to hammer out a truncated 2020 season, with the bell for opening day to ring in June. They are working on the granular details of games played, games paid, and service time.
You don't care how the money you spend is chopped up by the bean counters of MLB. You're not versed in the nuance of labor talks. Why should you be? Our deal with baseball is they keep us entertained through the scalding days of summer, and that for over a century they have provided us a peek into the sunny, verdant days after rotten winters.
The Final Four was a good milepost, a bridge between the frost and the fresh smells of outdoor food vendors. The Masters was another segue into spring. They're gone, choked out by COVID-19. Even baseball, which has been immune to wars and storms, has had to play matador to the virus.
Certain highbrow types don't see the value in sports. They are inessential and tangential to real life. They are, to quote a line from Annie Hall, a bunch of pituitary cases stuffing.a ball through a hoop. It may be a basketball reference, but it speaks to the overall view of some that sports are low-rent entertainment spawned by too much testosterone. They are to be pitied.
We want, we need our pastime. Especially here, in New York City, where baseball still has one of its final footholds. We want to sing the campy ballads. We want the sweet sounds of a bat cracking a ball, or a fastball pounding a catcher's mitt. We want to see dirt fly while someone dives for a ground ball, leaps, and flings to first base, the ball popping in the glove a nanosecond before the runner's toes tap the bag. We want the sweet smells of hot dogs and mustard and popcorn and, yes, even the bitter smell of spilled beer.
We want to know if Jacob deGrom can win a third-straight Cy Young. We want to see if Pete Alonso was a one-hit wonder or a sophomore superstar. We want to watch Gerrit Cole throw gas past batters in the Bronx. We want Aaron Judge to get healthy and hearty enough to reclaim his crown as Gotham's best baseball player.
Some of us have taken baseball for granted.I have. I jumped on the NFL's broad back and rode it for the last 20 years, often at the expense of MLB. If the Yankees or Mets aren't in the playoffs, my small brain embraces football. I joined the crowd that crowed baseball has too many games. Get it back to 154, the number played by the Boys of Summer. We should be shaving, not adding, the number of teams that qualify for October.
Right now, I'd take all of those arguments and concede them. There's no such thing as too much baseball. This proposed June start jars our ancient sensibilities. Baseball is our bedrock in this rocky world.
There will be certain signs or stats intended to tell us that we are close to whipping this tornadic virus that's been tearing through us.They talk about masks and gloves and sanitizer and ventilators, about flattening curves. We'll know we're OKwhen Alonso or Judge flattens a curveball, sending it soaring into the stands. It will mean baseball is back. Follow Jason on Twitter: @JasonKeidel
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Keidel: Baseball Is Our Bedrock In This Rocky World - WFAN
Androgen receptor stops tumor growth in the most common form of breast cancer – Newswise
WASHINGTONResearchers say they have found a viable new therapeutic strategy for estrogen receptor-positive (ER+) breast cancer, even cancers that are resistant to current standard of care treatments. Their new preclinical study was accepted for presentation at ENDO 2020, the Endocrine Societys annual meeting, and publication in a special supplemental section of the Journal of the Endocrine Society.
In various models of ER+ breast cancer, the most common form (about 75% of cases) of breast cancer, the researchers found that activating the androgen receptor decreased tumor growth, said Wayne Tilley, Ph.D., the studys principal investigator and a professor at the University of Adelaide in Australia. The androgen receptor is a protein in cells in men and women to which testosterone and other male reproductive hormones called androgens bind to elicit their effects, he explained. Importantly, androgens are found in women as well as men.
There is a prevailing assumption that the androgen receptor promotes malignancy in breast cancer, as it does in prostate cancer, Tilley said. Our study demonstrates that this is not the case for ER-driven breast cancer. Rather, the androgen receptor acts as a tumor suppressor.
ER+ breast cancer needs new drug treatments because as many as 35% of women with this type eventually become resistant to current hormone therapies, Tilley said. He noted that androgen receptor-stimulating drugs are under investigation for various diseases. The researchers tested one of these drugs, enobosarm, from a drug class called selective androgen receptor modulators, or SARMs, in models of ER+ breast cancer. These studies used ER+ breast cancer cell lines that are commercially available as well as tissues taken from breast cancer patients, including those resistant to current therapies. Some cell lines and human tissues were grown in culture dishes, and other cell lines and patient tumors were transplanted into mice to create patient-derived models.
In all models, the researchers found evidence that stimulating androgen receptor activity with enobosarm stopped tumor growth. From the different breast cancer models, they derived a gene signature of androgen receptor activity, which predicted cancer survival in participants in large studies of ER+ breast cancer. This androgen receptor signature outperformed other breast cancer prognostic signatures, he said.
When the investigators treated ER+ breast cancer tissues with enobosarm combined with current standard of care breast cancer drugs such as tamoxifen that target the estrogen receptor, Tilley said they observed better reduction in tumor growth than with the standard drug alone. Enobosarm is nonsteroidal and, according to Tilley, other researchers have found it to be safe in patients. Importantly, it does not cause women to develop male characteristics.
Treatment of ER+ breast cancer with an androgen receptor activator drug could be immediately tested in women, Tilley said.
This study received funding from the National Health and Medical Research Council and the National Breast Cancer Foundation, both in Australia. Tilley reported receiving a research grant from the maker of enobosarm, GTx Inc., now Oncternal Therapeutics.
The Endocrine Society canceled its annual meeting, ENDO 2020, amid concerns about COVID-19. Visit our online newsroom for more information on accepted abstracts, which will be published in a special supplemental section of the Journal of the Endocrine Society.
# # #
Endocrinologists are at the core of solving the most pressing health problems of our time, from diabetes and obesity to infertility, bone health, and hormone-related cancers. The Endocrine Society is the worlds oldest and largest organization of scientists devoted to hormone research and physicians who care for people with hormone-related conditions.
The Society has more than 18,000 members, including scientists, physicians, educators, nurses and students in 122 countries. To learn more about the Society and the field of endocrinology, visit our site at http://www.endocrine.org. Follow us on Twitter at @TheEndoSociety and @EndoMedia.
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Androgen receptor stops tumor growth in the most common form of breast cancer - Newswise
Trump admin supports girl athletes forced to compete with boys who say theyre female – Lifesite
March 25, 2020 (LifeSiteNews) The Trump administration has formally weighed in on the side of Selina Soule, Alanna Smith, and Chelsea Mitchell, the Connecticut high school athletes suing for the right to compete and be judged against only members of their ownsex.
The girls are suing the Connecticut Interscholastic Athletic Conference (CIAC) for allowing gender-confused boys to compete againstfemales, unjustly impairing their ability to earn not only competitive recognition, but also scholarships for their hard work. Soule has also filed a complaint on the matter with the U.S. Department of Educations Office for Civil Rights (OCR), which is still pending.
On Tuesday, U.S. attorney general William Barr signed a statement of interest on the matter, formally asserting the administrations stance that CIACs policyviolates federal Title IX rules that guarantee equal opportunities for girls in sports.
Title IX and its implementing regulations prohibit discrimination solely on the basis of sex, not on the basis of transgender status, and therefore neither require nor authorize CIACs transgender policy, the statement reads. To the contrary, CIACs construction of Title IX as requiringthe participation of students on athletic teams that reflect their gender identity would turn the statute on its head.
Under CIACs interpretation of Title IX, however, schools may not account for the real physiological differences between men and women. Instead, schools must have certain biological males namely, those who publicly identify as female compete against biological females, the statement continues. In so doing, CIAC deprives those women of the single-sex athletic competitions that are one of the marquee accomplishments of Title IX.
Chase Stranglo of the left-wing American Civil Liberties Union (ACLU), which is representing the transgender athletes, responded by declaring that the organizationsclients are two high school seniors who are just trying to enjoy their final track season of high school and who now have to contend with the federal government arguing against their right to equal educational opportunities. History will look back on these anti-trans attacks with deep regret and shame. In the meantime we will continue to fight for the rights of all girls to participate in the sports they love.
In fact, gender-confused students remain free to compete against members of their actual sex, and research affirms that boys who call themselves girls retain physical advantages over real girls.
Last June, the Journal of Medical Ethics published a paper concluding that healthy young men [do] not lose significant muscle mass [or power] when their circulating testosterone levels were reduced to [below International Olympic Committee guidelines] for 20 weeks, and indirect effects of testosterone on factors such as bone structure, lung volume, and heart size will not be altered by hormone therapy. Therefore, the advantage to transwomen [men] afforded by the [International Olympic Committee] guidelines is an intolerable unfairness.
Such findings are consistent with those of organizations like USA Powerlifting, which contends that men naturally have a larger bone structure, higher bone density, stronger connective tissue and higher muscle density than women. These traits, even with reduced levels of testosterone, do not go away. While MTF [male-to-female, meaning men who drug themselves to appear and perform more like women] may be weaker and less [muscular]than they once were, the biological benefits given them at birth still remain over than [sic] of a female.
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Trump admin supports girl athletes forced to compete with boys who say theyre female - Lifesite