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The energy required for a bacterium to grow and colonize the host is generated by metabolic and respiratory functions of the cell. Proton motive force, produced by these processes, drives cellular mechanisms including redox balance, membrane potential, motility, acid resistance, and the import and export of substrates. Previously, disruption of succinate dehydrogenase (sdhB) and fumarate reductase (frdA) within the oxidative and reductive tricarboxylic acid (TCA) pathways in uropathogenic E. coli (UPEC) CFT073 indicated that the oxidative, but not the reductive TCA pathway, is required for fitness in the urinary tract. Those findings led to the hypothesis that fumA and fumC encoding fumarase enzymes of the oxidative TCA cycle would be required for UPEC colonization, while fumB of the reductive TCA pathway would be dispensable. However, only UPEC strains lacking fumC had a fitness defect during experimental urinary tract infection (UTI). To further characterize the role of respiration in UPEC during UTI, additional mutants disrupting both the oxidative and reductive TCA pathways were constructed. We found that knock-out of frdA in the sdhB mutant strain background ameliorated the fitness defect observed in the bladder and kidneys for the sdhB mutant strain and results in a fitness advantage in the bladder during experimental UTI. The fitness defect was restored in the sdhBfrdA double mutant by complementation with frdABCD. Taken together, we demonstrate that it is not the oxidative or reductive pathway that is important for UPEC fitness per se, but rather only the oxidative TCA enzyme FumC. This fumarase lacks an iron-sulfur cluster and is required for UPEC fitness during UTI, most likely acting as a counter measure against exogenous stressors, especially in the iron-limited bladder niche.

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The oxidative fumarase FumC is a key contributor for E. coli fitness under iron-limitation and during UTI. - Physician's Weekly

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In Rushville, Illinois, the finishing touches are being put on a brand new $5 million fitness and community center.

It's all thanks to an anonymous donor.

Rushville residents have to travel nearly 30 minutes to work out.

Also, city leaders said the town lacks gym space for youth and adult sports leagues.

They said the new will fix those problems.

The exterior of the new Rushville Fitness and Community Center is nearly finished.

Construction crews are working to transform the inside into a new facility that promises to benefit the community.

"It will have a community and fitness room," Fitness and Community Center President Tim Ward said. "We're going to have a gymnasium that we've needed to bad in this community for years."

Ward said the new facility will fill a number needs in the community.

"We can have a multitude of events for children, like basketball, volleyball, indoor soccer, pickle ball for the adults and indoor walking for the seniors and everyone."

The center will also have an indoor pool to use year round.

Ward said right now, options are limited when it comes to exercise and activities. He said a multi-court gymnasium and indoor track will benefit people of all ages.

"We'll be able to do indoor walking and exercise daily and swimming and watch our kids play basketball on weekends in a nice new gymnasium," Ward said.

Rushville Mayor Carson Klitz said he hopes this attracts more people to town.

"It's going to help the town be more competitive," Klitz said. "When you couple that with the other things we have to offer, if we're attracting people to drive 30 miles to work, they'll come here if they have a choice between us and surrounding towns."

Ward said they're working to finish up dry wall and paint the gymnasium right now.

"This is a blessing for the community of Rushville," Ward said.

Construction crews said the plan is to open the facility in June. It will be owned by a 501(c)(3) corporation and operated as a not-for-profit.

The hours are yet to be determined, but the current plan is to allow 24/7 access to the fitness portion.

The cost is 35 dollars a month for ages 18 to 35 and 30 dollars a month for seniors.

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Rushville Fitness and Community Center near completion - WGEM

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MONTREAL Head coach Thierry Henry was the first to admit that his Montreal Impact team did not have the fitness level to match that of Deportivo Saprissain their Concacaf Champions League clash last week.

They didnt have 90 minutes in them, Henry said. Everybody knew. Its not an excuse, its a fact.

Henry gave credit to Saprissa and their head coach Walter Centeno for how they played in the second half. The Frenchman said that his counterpart changed tactical formations four times during the game in order to help his team get the 2-2 first-leg draw.

Montreal midfielder Samuel Piette admitted that Saprissas tactical changes surprised [them]" a little bit. Since the Impact have not been able to bridge the fitness gap between both clubs in a single week, Piette said Henry focussed on tactics.

This week, we worked on the possibilities that we could be facing [on Wednesday] if theres a change in the scoreline, Piette said. I think that this is how well be able to make up for the lack of fitness on our side.

The Impact started the first leg in spectacular fashion scoring two early goals. Henrys squad can attribute the early success to their five-man backline, which was unseen until last Wednesday. After the Impact coach admitted to not having a great preseason,the tactical change helped his squad get an early result.

Theres something that wasnt working in preseason, you dont have to be that clever to see that it wasnt working, Henry said. You also need to see what the team is offering you and how they respond.

So we went that way and it worked out at the beginning because it surprised them, I think. Are we going to play the same way [Wednesday]? I cant answer that.

The Impact are back home at Olympic Stadium with a 2-2 scoreline and two important away goals. For Montreal native Piette, it is imperative that his squad do not defend for 90 minutes to keep a 0-0 draw.

Its delicate but the most important will be not to be only defending for 90 minutes, Piette said. For one, its very tough physically and secondly, when its been 10 or 15 minutes that you havent had the ball you tend to lose your confidence on the ball.

The Impact will also host their MLS season opener on Saturday when they take on the New England Revolution (3 pm ET | MLS LIVE on ESPN+ in the US, TVAS in Canada). For Saphir Taider, having the first game of the season on the back of their minds will not affect how they play in the CCL.

Its not because were not favorites to win [the CCL] that we need to think of it as a bonus, Taider said. We need to play this competition with a desire to win and to go all the way. The team did it five years ago so why not this year?

Its modern football. Its the football of today where games follow each other and we need to do it too and play every three days. Its part of our jobs so its not really a problem.

As for Henry, being available to play even on a two-game week is whats expected of a soccer player.

Theyre here to be able to play and whoever is going to be fit to play is going to be at our disposal to start the game against New England, Henry said. Thats what you expect from your team, whatever game it is.

However, Henry added that he will delay his thought process for Saturdays formation until the final whistle of Wednesday's CCL affair.

For me, there is a sense of urgency in every game, Henry said. Now, does it have an influence on how were going to play against New England? I can only tell at the end of the game. Because I didnt expect that we would lose two players in the first 27 minutes of our first game. Thats something that you cannot predict. Lets see how well finish the game against Saprissa.

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Montreal Impact counting on tactics to bridge fitness gap in Concacaf Champions League second leg with Saprissa - MLSsoccer.com

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For those who continue to procrastinate on their New Years resolutions to work out more, Cornell has another barrier to using its fitness centers: price.

Student wellness comes at a cost at Cornell the University charges students an annual fee of $159 or a semester fee of $100 to access the fitness centers, such as access to any exercise equipment, cardio machines or weights.

The membership includes access to all five fitness centers and group fitness classes. Non-members are also provided with some free wellness services such as nutrition or fitness consultations, counseling to quit smoking and other programs dedicated to student wellness.

There are four gyms spread throughout campus: Helen Newman and Appel are located on North Campus, Teagle is on Central and Noyes sits in West Campus.

In the Ivy League, Cornell is not unique in charging its students for an annual or semester-based gym membership. Columbia University and The University of Pennsylvania also charge their undergrads for access. Columbia pricesits membership at $247 for the spring semester pass, while Penns fee is $334 for the year.

However, other universities likeHarvard, Yale, Princeton, Brown, Dartmouth and MIT offer undergraduates free access to their fitness centers.

For many students, Cornells gym fee deters them from utilizing any of the Universitys facilities. Craig Schulman 22 said he neglects going to the gym because of the hefty fee.

[Its] why I dont have a membership. A lot of my friends at other schools arent charged for the gym and $159 is a lot of money.

Lance Rombro 23 also voiced his annoyance.

It seems unreasonable that we attend such a prestigious and well-endowed institution, yet the University makes working-out and student wellness a luxury, Rombro said.

However, Cornell does offer some costless options through its Fitness for Free programs. programs. One of these options is that students can access Appel, Helen Newman or Noyes without charge on Friday and Saturday evenings, but a swipe-in is required at any other time during the week.

Students can also play basketball, table-tennis and badminton at Noyes and Helen Newman, or take a free PE class.

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Student Fitness, Health and Wellness: A Necessity or Luxury in the Eyes of the University? - Cornell University The Cornell Daily Sun

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With new exercises invented every week, new gurus trending by the day and a fresh study that contradicts all the other ones released every time you think youre getting the hang of things, its easy to think that fitness is confusing but it isnt.

The fundamentals stay the same, and the science is pretty well agreed so by simply arming yourself with a few basic facts, you can step into any gym forewarned against whatever fresh nonsense the #fitstagrammers are preaching. These are the 10 biggest myths in fitness exercise your synapses for a couple of minutes by memorising them, and do your curls with confidence.

Yes, theres something masochistically satisfying about limping your way down a flight of stairs the morning after a big legs workout, but delayed onset muscle soreness Doms to its Insta-buddies isnt actually a convincing indicator of progress. Its thought to be caused by micro-tears in muscle, and tends to crop up when you do movements youre not used to, when you deliberately slow down the eccentric (or muscle-lengthening) part of whatever move youre doing (such as the downward bit of a squat) or just do a ridiculous number of reps. Conversely, then, you can eliminate soreness almost entirely by keeping the reps low, or doing moves that dont have an eccentric, such as throws and sled pushes. There is such a thing as pain-free progress.

There are two key ways to get stronger: increasing the size of your individual muscle fibres, and recruiting more of them to fire together when you need to use them. The first is what bodybuilders aim to do, but the second is what your body would do automatically if you had to lift a car off a loved one. In sports where excess size is a negative, it is what competitors teach themselves to do. This is how female Olympic weightlifters in the lighter weight categories can outlift larger men. Getting big requires specific, targeted training, including lots of volume and extra calories and protein and it almost never happens by accident.

This ones been popularised by modern fitness gurus, who will (fairly sensibly) point out that weight isnt a true measure of progress, as fluctuations in the amount of water being retained can lead to day-to-day shifts in the numbers, and putting on muscle can lead to the numbers going up while youre making progress in the right direction. This doesnt mean you should toss away your scales entirely. Yes, you have to understand that short-term fluctuations are inevitable and dont represent changes in body fat, says Emma Storey-Gordon, the trainer/owner of ESG Fitness. But, over time, changes in scale weight are predictive of body fat. Even if you are also building muscle, the rate at which you can lose fat will be much quicker than the rate at which you can build muscle. Dont become overreliant on them, but scales can show whether youre moving in the right direction.

Actually, its more like the opposite: properly done squats will strengthen the stabiliser muscles around your knee joints, safeguarding you against injury as well as making you a bit more capable of bounding up escalators. As for running, a 20-year study conducted by Stanford University found that consistent runners (many of whom were well into their 70s by the time the research period ended) showed a lower incidence of arthritis than non-runners as they aged. It also showed that runners have a lower risk of osteoarthritis and hip replacements, suggesting that pounding pavements isnt actually as bad for you as advertised.

While we all lived in the offline wilderness, the myth persisted that you could, for instance, target the fat around your midriff by doing hundreds of situps. That myth has been mostly wiped by the ubiquity of the internet, but replaced by the more subtle half-truth that its possible to single out problem areas by thinking hormonally: that since, for instance, the stress hormone cortisol causes belly-fat buildup, a bit more sleep and a few sessions on the Calm app should see your abs emerge. And while this is technically, sort of, true, deliberately messing with your hormones is tougher than advertised and not really advisable. The truth is, we all have stubborn fat areas that seem to take the longest to get lean, says Storey-Gordon. There are various reasons for this hormones and sex both play a role, for instance. These cant be easily changed, so you cant really choose where you lose fat from. Dont give up, though. Stubborn areas will get leaner alongside everything else. Patience is the key.

CrossFit and endless neon-tinted, EDM-soundtracked fitness classes have made rest a four-letter word in the fitness industry, but constant movement for the sake of it could actually be hindering your gains, not helping them. For most people especially beginners periods of recovery between sets or intervals allows for higher-intensity, better-quality movement, lower risk of injury and a greater training stimulus that is likely to lead to superior results, says the performance and wellbeing coach George Anderson. Or, in other words: if you push yourself for an hour straight, youll be forced to lift lower weights, go slower and generally put in less work than you might with some strategic downtime. And the optimum varies for fat loss, anywhere from 15 to 60 seconds between sets is ideal, but for strength you might spend five minutes preparing for ultra-intense efforts.

As sparse-and-spartan gym spaces emphasising basic barbell movements have proliferated, so, too, has the idea that using machines to train is at best inefficient, at worst dangerous. Machines force your body into awkward, over-linear movement patterns, goes the theory reducing the input from important stabiliser muscles and stopping you from moving naturally. But while there is some truth to this, not every machine is the enemy. Whether youre a time-poor, technique-free novice or a more advanced lifter, machines can involve less setup, allow more work and provide extra stimulus to isolated muscle groups, says the trainer Dan Osman. That said, the leg press is no substitute for learning to squat properly.

Lets be honest: youve never seen Britains greatest living Olympian, Sir Steve Redgrave, dry-heaving over the side of a cross-trainer. It may be intuitive and burn some calories, but thats all this outdated relic offers, says Dr Cameron Nichol, the founder of RowingWOD. When done correctly, the rowing machine uses 86% of your muscles spanning nine major muscle groups. The rower also works with the time you have if you need a short, horrible finisher, a 500-metre sprint will leave you sucking air and burning fat, while a more ponderous 10k feels almost meditative and the Olympic-length 2k is a test of will as much as power.

Once, the four-minute Tabata 20 seconds of work and 10 seconds of rest, repeated eight times seemed the logical endpoint of the workout-shortening craze, with claims that it could replace much longer training sessions while offering roughly the same benefits. Now it seems almost glacial, with three, two, and one-minute workouts promising to harness high-intensity interval trainings (HIIT) mystical powers and leave you more time for Candy Crush. The truth? Anything is better than nothing, and its certainly possible to make some gains in whatever limited time you have, but longer workouts have effects that no micro-workout can mimic. Oh, and by the way: in the original Tabata study, the test subjects who were professional cyclists worked so intensely that some of them refused to countenance trying the protocol again. If youre not doing that, theres no guarantee it will work as advertised.

Is running better than lifting for longevity? Do you need the mobility yoga offers more than a really jacked set of quads? Is Zumba just a waste of valuable time that you could spend boxercising? Whatever training style you experiment with, youll find someone ready to argue that everything else is useless and stupid, that you should stick with them or go home, says Dr Michael Banna. This kind of absolutism risks deflating people by telling them that their efforts have been pointless. The reality is, any physical activity has health benefits; the right type is the one that doesnt injure you, make you sad or make you want to stop. Ideally your physical activity should include a mixture of cardio, resistance and mobility work spread across the week but do what you enjoy.

Joel Snape is a former editor of Mens Fitness and runs the website LiveHard

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Soreness is good and scales are pointless: the 10 biggest myths in fitness - The Guardian

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Differences in health policy weren't the only bones presidential candidates had to pick last week. They also sparred over details of their personal health. And with the next debate and Super Tuesday primaries fast approaching, these skirmishes are likely to escalate.

In the run-up to the Las Vegas Democratic presidential primary face-off, Vermont Sen. Bernie Sanders' national press secretary, Briahna Joy Gray, told CNN that opponents are trying to use his October heart attack against him. Then she mistakenly claimed that Mike Bloomberg "has suffered heart attacks in the past" a statement she quickly walked back after a Bloomberg adviser said in a tweet it was a "Trumpy lie."

He did not have a heart attack, Bloomberg's camp explained, trying to differentiate its candidate's health status. He had stents. The former New York mayor, according to the campaign, had coronary stents inserted two decades ago after a cardiac test indicated they might be useful.

Feathers still ruffled, the two candidates went at it again on the debate stage.

"I think the one area, maybe, that Mayor Bloomberg and I share, you have two stents, as well," Sanders said Thursday to his rival onstage.

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Bloomberg responded, "Twenty-five years ago."

It's not surprising, with the oldest crop ever of presidential candidates, that their vital signs are becoming a talking point.

"When it comes to politics, personal health is just one more issue to try and leverage," said Arthur Caplan, a professor of bioethics at NYU School of Medicine in New York City.

That got us wondering how this information fits into the facts voters weigh. And in evaluating a candidate's long-term health or electability, does it really matter whether a patient got a stent as part of treatment for a heart attack, like Sanders, or for another reason, such as to relieve chest pain or following a cardiac stress test, like Bloomberg?

"In this day and age, with the way technology has advanced and the skill sets of the cardiologists, I would say they are practically the same. We expect good results for both," said Dr. Hadley Wilson, a practicing cardiologist in Charlotte, North Carolina, and a member of the American College of Cardiology's board of trustees.

Stents are almost always used when a person is having a heart attack.

Heart attacks can occur when plaque breaks off inside the blood vessels of the heart, causing a blockage. To open the blocked artery, physicians insert stents, which are small, wire-mesh tubes. Afterward, patients are treated with medications to reduce the risk of subsequent heart attacks.

Back when Bloomberg got his, they were commonly used in nonemergency situations to prop open narrowing arteries, with the thought that might prevent a heart attack, said Dr. Suzanne Steinbaum, a cardiologist in New York and a spokesperson for the American Heart Association.

But, since then, "we learned stents don't prevent a heart attack and that using medication might be equally beneficial," Steinbaum said, adding that the best preventive measures are lifestyle choices, such as eating a good diet, exercising and not smoking. Patients still sometimes get stents to alleviate symptoms, such as chest pain, or for other reasons.

Thursday's debate also highlighted the broader question: Just how much of a candidate's medical history is fair game for public consumption?

Sanders, who faced criticism in October for delays in reporting his condition, said he has since released "the full report of that heart attack" including letters from his primary care doctor and two cardiologists attesting to his overall health and recovery.

But candidate Pete Buttigieg, the former mayor of South Bend, Indiana, said Sanders had not provided enough detail and neither, he said, had the others.

"Under President Obama, the standard was that the president would release full medical records, do a physical and release the readout," he said during the debate. "Now, President Trump lowered that standard. He said just a letter from a doctor is enough. And a lot of folks on this stage are now saying that's enough."

Buttigieg himself has yet to provide a full medical record.

"But I am certainly prepared to get a physical, put out the results," he said during the debate. "I think everybody here should be willing to do the same."

Some observers agree there's no such thing as TMI (too much information) when it comes to POTUS (the president of the United States).

"When the country is hiring someone to have their finger on the nuclear button, the expectation of personal privacy is very, very limited," said David Blumenthal, head of the Commonwealth Fund and co-author of "The Heart of Power: Health and Politics in the Oval Office." "It's hard to imagine something [health-related] that would not be relevant."

That argument, though, doesn't always hold up.

When he ran for president in 2008, the then-70-year-old Sen. John McCain released more than 1,000 pages of his medical records.

By contrast, the campaigning Donald Trump initially released a glowing letter from his personal physician that concluded he would be "the healthiest individual ever elected to the presidency." After criticism that the letter lacked specifics, Trump added information on his height, weight and cholesterol levels and went on to become the oldest president, at age 70, to take office, beating out Ronald Reagan, who was just weeks shy of that milestone on Inauguration Day in 1981.

This year, candidates Bloomberg and Sanders are both 78; former Vice President Joe Biden, 77; and Sen. Elizabeth Warren, 70. Sen. Amy Klobuchar is 59, and Buttigieg is the youngest, at 38.

Anything that might be "relevant to a candidate's ability and competence to govern and their longevity of service" should be disclosed, said Blumenthal, who is also a medical doctor.

Voters could then decide what they thought was important. The information might also affect how voters view the choice of a vice president, especially if the candidate for the highest office had a serious illness or something else that might limit their term, he said.

Specifically which records, though, and how to release them is a complicated issue.

Caplan, at NYU, has long advocated setting up a special independent medical panel to evaluate presidential candidates' health and make their findings public.

"It would be like an executive physical, which is what a lot of companies do before they pick a CEO," he said.

And deciding what to test for would be, in itself, complicated. Without a special panel which, even Caplan admits, would meet political inertia the challenges would be numerous. Even locating all the necessary records would be difficult.

The candidates "may have moved around the country, their doctors may have died, or records may not be available," noted Lawrence Altman, who covered many presidential elections as a reporter for The New York Times and is now a global scholar at the Woodrow Wilson International Center for Scholars.

While there is no specific requirement that candidates release any information at all, what readers and voters want to know varies widely.

"It depends on their interest in the candidate," Altman said. "A lot of people superimpose their political choices or feelings on the medical aspect. They are willing to dismiss something if they really like the candidate or make a big issue about it if they don't like the candidate."

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Getting to the heart of presidential fitness: how much do we need to know? - Salon

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Annie Thorisdottir recently announced that she and her partner were expecting a baby. As a result, she has officially declined her invitation to the 2020 CrossFit Games.

Thorisdottir is the two time winner of the CrossFit Games. As a result, she has become one of the most popular, and recognizable faces in the sport. Not to mention, it certainly helps that she is also a very sweet person outside of competition, as well.

That is why, when Thorisdottir revealed that she and fellow CrossFit athlete Frederik Aegidius were expecting a child, it was met with universal praise from the CrossFit community. However, when fans realized that her due date of August 5th coincided with the end of the CrossFit Games, there were some concerns. Obviously being in her third trimester makes competing a little more difficult.

Now, three weeks after the initial announcement, the inevitable had been confirmed. According to an announcement from CrossFit HQ, Annie Thorisdottir has officially declined her invitation to the Games.

Two-time Fittest Woman on Earth, five-time podium finisher 11-time CrossFit Games qualifier Annie Thorisdottir has declined her invitation to the 2020 Reebok CrossFit Games.

Thorisdottirs spot will pass to Maddie Sturt, who sits next in line for an invite as a result of placement in the 2020 CrossFit Open.

Thorisdottir scored second place in the 2020 CrossFit Open, which is where her invitation came from. Subsequently, as the statement explained, her invite goes to Maddie Sturt. This gives the 23-year old Australian athlete her fifth appearance in the big competition.

As much as fans are sad that they will not see Annie Thorisdottir at the 2020 CrossFit Games, you cant help but be happy for her, and Frederik Aegidius. This will be just her second time missing the Games, since 2009. Regardless, when the competition is taking place she is likely going to have some bigger things on her mind.

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Annie Thorisdottir Officially Declines Invitation To 2020 CrossFit Games - FitnessVolt.com

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Technogym founder Nerio Alessandri with actor Sylvester Stallone

You may never have heard of Nerio Alessandri, but you may well have used the gym equipment he designed.

Alessandri is the founder of Technogym, one of the most popular gym equipment brands in the world, with 50 million users globally across 100 countries. Founded in 1983, the company now makes products ranging from free weights to rowing machines.

It has already supplied exercise bikes, treadmills and more for several Olympic Games and will this year provide equipment for the event in Tokyo. It has also sponsored Formula 1 and soccer teams including A.C. Milan.

The business is now worth around 2.2 billion ($2.4 billion) and since it went public on the Milan Stock Exchange in May 2016 has seen its share price increase by 156%.

Speaking to CNBC, Alessandri said being self-funded helped the company to grow sustainably in the early days. He maintained a steady cashflow by getting customers to pay half of the equipment price upfront and then the other half upon delivery.

In fact, he says that it was only 12 years ago some 25 years after the company was founded that Technogym took on private equity investment.

He attributes part of the business' success to "sustainable" and "profitable" growth.

Before Alessandri hit the big time and started rubbing shoulders with the likes of Bill Gates, Arnold Schwarzenegger and Sylvester Stallone, he began by designing the first prototypes of his fitness equipment in his family's garage, near Cesena, Italy.

Born into a farming family, Alessandri describes in his book "Born to Move" how he was brought up by parents "who didn't have much money but who did have a great deal of dignity and humility."

He says that he "quickly caught on that money was a problem" for his family and so, at age 10, started helping out his parents by taking an afternoon job packing fruit at his grandfather's warehouse.

At age 12, he realized he could make extra money using his passion for technical and mechanical design.

He tells how a wealthy friend at school asked him for advice on the best model of portable stereo to buy, which were "all the rage" in Italy in the 1970s. Alessandri then bought it off his friend for a half the price after he got bored with it, refurbished and sold it on for a profit.

Alessandri did the same with a Caballero scooter and Volkswagen Golf car: buying, improving and selling them on for more money.

The Alessandri family garage where Technogym was launched near Cesena, Italy.

Not long after graduating from high school, Alessandri got restless and wanted to build a business of his own. Initially, he revisited his childhood dream of becoming a fashion designer and sent a letter to legendary Italian designer Giorgio Armani, who was opening a store in the region.

Alessandri never did hear back from Armani, but while continuing at his day job he became interested in the world of fitness after visiting a local gym and seeing that it only offered very basic equipment.

Seeing an opportunity to put his design skills to good use, he started designing equipment in his father's garage and, in 1983 aged 22, he founded Technogym.

As orders for his gym equipment started rolling in, Alessandri quit his day job and when Technogym outgrew the garage, he moved his burgeoning business into an old mattress factory.

Alessandri said another factor behind Technogym's success is its focus on culture.

He told CNBC that his goal was to "leave a legacy for the next generation" which would be made possible by having a strong culture.

Part of this comes down to maintaining a "curiosity" and "passion" for the business, he said, which fuels "continuous improvement," and he also emphasized the importance of being honest and transparent.

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How Nerio Alessandri started Technogym, worth $2.4 billion, in his garage in Italy - CNBC

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Developer Kevin Nguyen has broken ground on Juban Square, his planned 23,000-square-foot shopping center on Juban Road across from Juban Crossing in Denham Springs, and expects to begin vertical construction on the retail strip in the next 30 days.

Hes also signed a lease with another new tenant: Regymen Fitness will open its fourth local locationand 17th nationwidein the center later this year, according to Regymen co-owner Donnie Jarreau.

The boutique fitness conceptwhich combines cardio, strength training and boxing workouts in a group exercise settingwill join two previously announced tenants in the center, Izzos Illegal Burritos and Lit Pizza.

Though Baton Rouge has a notoriously competitive market for health and fitness clubs, Jarreauwho has owned various fitness clubs in the area since the 1990ssays the bedroom communities in Ascension and Livingston parishes are still underserved.

We opened our third Regymen location in Gonzales last year and it has proven to be our best location yet, he says. Theres not as much competition in the suburban markets and still a lot of opportunity out there.

Jarreaus other local Regymen locations are on Corporate Boulevard across from Towne Center at Cedar Lodge and on Bluebonnet Boulevard near Perkins Road.

As for other tenants at Juban Square, which will spread over 2.3 acres, Nguyen says hes talking to service providers like hair and nail salons and health care-related businesses. Several restaurant chains also have expressed an interest in the center, though only one food-service space remains available.

Nguyen hopes to complete lease negotiations, which are being handled by Doug Ferris and Sara Furman of ReMax First, in the next 30-60 days.

The center is scheduled to be completed and open by late summer.

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Kevin Nguyen's Juban Square going vertical, signs deal with Regymen Fitness - Greater Baton Rouge Business Report

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Googles Wear OS has a bad rap in the tech industry, mostly for the lack of software innovation that makes the platform seem stagnant. While most people dont see the benefit of owning a smartwatch, Wear OS is not doing the category any favors. Its simply not on the level of other wearable operating systems from companies like Samsungand Apple.

Related: The best Wear OS watches (January 2020)

Thankfully, it looks like Google is finally ready to make some changes to Wear OS. It has rolled out a new survey (h/t Droid Life) through its user experience research program asking participants for feedback on how to improve Wear OS. The survey reportedly focuses on health and fitness features such as sleep analysis, SPo2 tracking, sleep apnea detection, heartbeat alerts, and more.

Googles survey also asks participants how they feel about features like medical device and gym equipment pairing. Below is the full list of Wear OS features reportedly mentioned in Googles survey:

Obviously, we dont know if all these features are headed to Wear OS, but Googles recent acquisition of Fitbit might mean the company is seriously thinking of stepping up its health-tracking game.

Related: The best Fitbit trackers and smartwatches

The big question is, would you use smartwatches powered by Wear OS if it had more fitness and health features like the ones mentioned above? Do you feel positive about the future of Wear OS if Google were to add more health-focused features on the platform? Cast your vote in the poll, and be sure to drop us a line in the comments. You all probably have some opinions, so we want to hear them!

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Poll: Would you use Wear OS if it had these fitness features? - Android Authority

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