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de La Torre, S., Snowdon, C. T. & Bejarano, M. Effects of human activities on wild pygmy marmosets in Ecuadorian Amazonia. Biol. Conserv. 94, 153163 (2000).
Article Google Scholar
Turvey, S. T. & Crees, J. J. Extinction in the Anthropocene. Curr. Biol. 29, R982R986 (2019).
Article CAS PubMed Google Scholar
Newbold, T. et al. Global effects of land use on local terrestrial biodiversity. Nature 520, 4550 (2015).
Article CAS PubMed Google Scholar
di Marco, M., Venter, O., Possingham, H. P. & Watson, J. E. M. Changes in human footprint drive changes in species extinction risk. Nat. Commun. 9, 19 (2018).
Article Google Scholar
Ceballos, G. & Ehrlich, P. R. Mammal population losses and the extinction crisis. Science 296, 904907 (2002).
Article CAS PubMed Google Scholar
Yang, L., Shi, K. C., Ma, C., Ren, G. P. & Fan, P. F. Mechanisms underlying altitudinal and horizontal range contraction: the western black crested gibbon. J. Biogeogr. 48, 321331 (2021).
Article Google Scholar
Li, X. et al. Human impact and climate cooling caused range contraction of large mammals in China over the past two millennia. Ecography 38, 7482 (2015).
Article Google Scholar
Fan, P. F., Ni, Q. Y., Sun, G. Z., Huang, B. & Jiang, X. L. Gibbons under seasonal stress: The diet of the black crested gibbon (Nomascus concolor) on Mt. Wuliang, Central Yunnan, China. Primates 50, 3744 (2009).
Article PubMed Google Scholar
Hanya, G. Seasonal variations in the activity budget of Japanese macaques in the coniferous forest of Yakushima: effects of food and temperature. Am. J. Primatol. 63, 165177 (2004).
Article PubMed Google Scholar
Mcconkey, K. R., Aldy, F., Ario, A. & Chivers, D. J. Selection of fruit by Gibbons (Hylobates muelleriagilis) in the Rain Forests of Central Borneo. Int. J. Primatol. 23, 123145 (2002).
Article Google Scholar
Amato, K. R. et al. Habitat degradation impacts black howler monkey (Alouatta pigra) gastrointestinal microbiomes. ISME J. 7, 13441353 (2013).
Article CAS PubMed PubMed Central Google Scholar
McKenney, E. A., OConnell, T. M., Rodrigo, A. & Yoder, A. D. Feeding strategy shapes gut metagenomic enrichment and functional specialization in captive lemurs. Gut Microbes 9, 202217 (2018).
Article CAS PubMed PubMed Central Google Scholar
Baniel, A. et al. Seasonal shifts in the gut microbiome indicate plastic responses to diet in wild geladas. Microbiome 9, 120 (2021).
Article Google Scholar
Hicks, A. L. et al. Gut microbiomes of wild great apes fluctuate seasonally in response to diet. Nat. Commun. 9, 118 (2018).
Article CAS Google Scholar
Huang, G. et al. Seasonal shift of the gut microbiome synchronizes host peripheral circadian rhythm for physiological adaptation to a low-fat diet in the giant panda. Cell Rep. 38, 110203 (2022).
Article CAS PubMed Google Scholar
Fan, P. F. et al. Description of a new species of Hoolock gibbon (Primates: Hylobatidae) based on integrative taxonomy. Am. J. Primatol. 79, e22631 (2017).
Article Google Scholar
Fan, P. F., Turvey, S. T. & Bryant, J. V. Hoolock tianxing (amended version of 2019 assessment). IUCN Red List of Threatened Species 20202021 (2020).
McGrosky, A. et al. Gross intestinal morphometry and allometry in primates. Am. J. Primatol. 81, e23035 (2019).
PubMed Google Scholar
Fan, P. F., Ai, H.-S., Fei, H. L., Zhang, D. & Yuan, S. D. Seasonal variation of diet and time budget of Eastern hoolock gibbons (Hoolock leuconedys) living in a northern montane forest. Primates 54, 137146 (2013).
Article PubMed Google Scholar
Kartzinel, T. R., Hsing, J. C., Musili, P. M., Brown, B. R. P. & Pringle, R. M. Covariation of diet and gut microbiome in African megafauna. Proc. Natl Acad. Sci. USA 116, 2358823593 (2019).
Article CAS PubMed PubMed Central Google Scholar
Ley, R. E. et al. Evolution of mammals and their gut microbes. Science 320, 16471651 (2008).
Article CAS PubMed PubMed Central Google Scholar
Levin, D. et al. Diversity and functional landscapes in the microbiota of animals in the wild. Science 372, eabb5352 (2021).
Article CAS PubMed Google Scholar
Xiao, K. P. et al. Adaptation of gut microbiome and host metabolic systems to lignocellulosic degradation in bamboo rats. ISME J. 16, 19801992 (2022).
Article CAS PubMed PubMed Central Google Scholar
Solden, L. M. et al. Interspecies cross-feeding orchestrates carbon degradation in the rumen ecosystem. Nat. Microbiol. 3, 12741284 (2018).
Article CAS PubMed PubMed Central Google Scholar
Khanal, S. K. Microbiology and biochemistry of anaerobic biotechnology. Anaerobic Biotechnology for Bioenergy Production: Principles and Applications (ed. Khanal, S. K.) 2940 (John Wiley & Sons, Inc., USA, 2008).
Lozupone, C. A., Stombaugh, J. I., Gordon, J. I., Jansson, J. K. & Knight, R. Diversity, stability and resilience of the human gut microbiota. Nature 489, 220230 (2012).
Article CAS PubMed PubMed Central Google Scholar
Weimer, P. J. Redundancy, resilience, and host specificity of the ruminal microbiota: Implications for engineering improved ruminal fermentations. Front. Microbiol. 6, 296 (2015).
Article PubMed PubMed Central Google Scholar
Gharechahi, J., Vahidi, M. F., DIng, X. Z., Han, J. L. & Salekdeh, G. H. Temporal changes in microbial communities attached to forages with different lignocellulosic compositions in cattle rumen. FEMS Microbiol. Ecol. 96, fiaa069 (2020).
Article CAS PubMed Google Scholar
Huttenhower, C. et al. Structure, function and diversity of the healthy human microbiome. Nature 486, 207214 (2012).
Article CAS Google Scholar
Coyte, K. Z., Schluter, J. & Foster, K. R. The ecology of the microbiome: Networks, competition, and stability. Science 350, 663666 (2015).
Article CAS PubMed Google Scholar
Relman, D. A. The human microbiome: ecosystem resilience and health. Nutr. Rev. 70, S2S9 (2012).
Article PubMed Google Scholar
Giongo, A. et al. Toward defining the autoimmune microbiome for type 1 diabetes. ISME J. 5, 8291 (2011).
Article CAS PubMed Google Scholar
de Cruz, P. et al. Characterization of the gastrointestinal microbiota in health and inflammatory bowel disease. Inflamm. Bowel Dis. 18, 372390 (2012).
Article PubMed Google Scholar
Johnson, A. J. et al. Daily sampling reveals personalized diet-microbiome associations in humans. Cell Host Microbe 25, 789802 (2019).
Article CAS PubMed Google Scholar
Amato, K. R. et al. The gut microbiota appears to compensate for seasonal diet variation in the Wild Black Howler Monkey (Alouatta pigra). Microb. Ecol. 69, 434443 (2015).
Article CAS PubMed Google Scholar
Springer, A. et al. Patterns of seasonality and group membership characterize the gut microbiota in a longitudinal study of wild Verreauxs sifakas (Propithecus verreauxi). Ecol. Evol. 7, 57325745 (2017).
Article PubMed PubMed Central Google Scholar
Maurice, C. F. et al. Marked seasonal variation in the wild mouse gut microbiota. ISME J. 9, 24232434 (2015).
Article CAS PubMed PubMed Central Google Scholar
Mackie, R. I. et al. Ecology of uncultivated Oscillospira species in the rumen of cattle, sheep, and reindeer as assessed by microscopy and molecular approaches. Appl Environ. Microbiol. 69, 68086815 (2003).
Article CAS PubMed PubMed Central Google Scholar
Ren, T. et al. Seasonal, spatial, and maternal effects on gut microbiome in wild red squirrels. Microbiome 5, 114 (2017).
Article Google Scholar
Flint, H. J., Scott, K. P., Duncan, S. H., Louis, P. & Forano, E. Microbial degradation of complex carbohydrates in the gut. Gut Microbes 3, 289306 (2012).
Article PubMed PubMed Central Google Scholar
White, B. A., Lamed, R., Bayer, E. A. & Flint, H. J. Biomass utilization by gut microbiomes. Annu. Rev. Microbiol. 68, 279296 (2014).
Article CAS PubMed Google Scholar
Gomez, A. et al. Temporal variation selects for diet-microbe co-metabolic traits in the gut of Gorilla spp. ISME J. 10, 514526 (2016).
Article CAS PubMed Google Scholar
Popovich, D. G. et al. The western lowland gorilla diet has implications for the health of humans and other hominoids. J. Nutr. 127, 20002005 (1997).
Article CAS PubMed Google Scholar
van der Hee, B. & Wells, J. M. Microbial regulation of host physiology by short-chain fatty acids. Trends Microbiol. 29, 700712 (2021).
Article PubMed Google Scholar
Bergman, E. N. Energy contributions of volatile fatty acids from the gastrointestinal tract in various species. Physiol. Rev. 70, 567590 (1990).
Article CAS PubMed Google Scholar
Kim, C. H., Park, J. & Kim, M. Gut microbiota-derived short-chain fatty acids, T cells, and inflammation. Immune Netw. 14, 277288 (2014).
Article PubMed PubMed Central Google Scholar
Hossain, K. S., Amarasena, S. & Mayengbam, S. B Vitamins and their roles in gut health. Microorganisms 10, 1168 (2022).
Article CAS PubMed PubMed Central Google Scholar
LeBlanc, J. G. et al. Bacteria as vitamin suppliers to their host: a gut microbiota perspective. Curr. Opin. Biotechnol. 24, 160168 (2013).
Article CAS PubMed Google Scholar
Zhang, S. et al. Gut microbiota serves a predictable outcome of short-term low-carbohydrate diet (LCD) intervention for patients with obesity. Microbiol. Spectr. 9, e0022321 (2021).
Article PubMed PubMed Central Google Scholar
Durrer, C. et al. A randomized controlled trial of pharmacist-led therapeutic carbohydrate and energy restriction in type 2 diabetes. Nat. Commun. 12, 18 (2021).
Article Google Scholar
Reimer, R. A. Establishing the role of diet in the microbiotadisease axis. Nat. Rev. Gastroenterol. Hepatol. 16, 8687 (2019).
Article PubMed Google Scholar
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10 High Fiber Vegetables to Add to Your Diet – Real Simple
We all know that consuming a good amount of fiber is important for our overall health, but do we really know why? Nutrition expert, Meghan Novoshielski MS, RDN, explains: "Eating more high-fiber vegetables is one of the best things people can do for their health. She adds, "Fiber helps with weight loss, keeps blood sugars stable, protects cardiovascular and digestive health, and fuels a healthy gut microbiome. And while many vegetables contain an adequate amount of fiber, Novoshielski says that a good rule of thumb for even more fiber is to grab veggies that are darker in color, like beetroot, artichokes, and dark leafy greens such as Swiss chard.
The American Heart Association recommends that adults eat between 25 to 30 grams of fiber per day, but since many people dont get enough vegetables in their daily diets, Novoshielski recommends adding high-fiber ingredients (such as veggies) to your meals. For example, you can top your pizza with broccoli and spinach, or add zucchini and tomato to an omelet or frittata.
Want to know which high fiber vegetables to add to your diet? Keep reading for more!
Did you know that a serving of boiled carrots contains more fiber than raw carrots? But dont worry, its not by mucha cup of boiled carrots has 5 grams of fiber, while a medium-sized raw carrot has about 2 grams. Whether youre adding them to a salad, curry, or dipping them into delicious hummus, carrots are a great veggie to have on hand each week since theyre so versatile.
It should come as no surprise that broccoli is one of the healthiest vegetables to add to your diet. Katherine Gomez, a registered dietitian, notes: Just one cup of broccoli has about 5 grams of fiber. It also contains antioxidants and vitamin C, which can strength our immune system and lower the risk of chronic illness.
Cauliflower is similar to broccoli in that it has many beneficial minerals and vitamins, but it doesnt contain quite as much fiber. In fact, theres 2 grams of fiber in a cup of cauliflower, which is about half the amount you'll find in the same serving of broccoli. That being said, cauliflower is still a great vegetable to add to your meals and eat often.
If you love eggplant Parmesan or stuffed eggplant, youll be happy to know that those dishes contain a good amount of fiber. Just like cauliflower, eggplant has about 2 grams of fiber per cup.
Swiss chard has about 4 grams of fiber per cup, and is a great green to incorporate into pasta dishes, salads, or a satisfying frittata. Stop by the farmers market during the summer and early fall to grab some Swiss chard at its freshest.
Is there anything more delicious than a bacon-wrapped Brussels sprout with a drizzle of balsamic, or a shredded Brussels sprout salad? These crunchy little green veggies have over 3 grams of fiber per cup, and are truly a superfood. They have plenty of nutritional benefits, and may even protect against certain types of cancer.
When artichokes are in season, theyre one of the most delicious vegetables to enjoy. And since theyre naturally so flavorful, you dont need to do much other than cook or steam them. Artichokes have about 4 grams of fiber per serving, and are also rich in calcium.
Beets are considered to be a natural laxative, and its certainly because theyre high in fiber at 4 grams per cup. Whether youre chopping them up for a goat cheese and walnut salad, or making a beautiful Pink Hummus, beets have a mildly sweet flavor that make them the perfect addition to so many dishes.
If Popeye taught us anything, its that spinach can make us grow big and strong. Katherine Gomez, RD, says: "Spinach has about 4 grams of fiber per cup, and it also contains iron, which is necessary for producing red blood cells. Enjoy spinach as a side, like in this Spanakopita Creamed Spinach recipe, or mix a handful of it into your favorite pasta dish.
Theres a reason why peas are usually one of the first vegetables we introduce to babies. "A cup of peas has about 9 grams of fiber, and they are an excellent source of B vitamins, which are crucial for energy metabolism," says Gomez.
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Idea of putting city’s ‘road diets’ on ballot fizzles – scottsdale.org
Around Scottsdale, the notion of so-called road diets making vehicle traffic narrower by adding bike lanes is so hot it sizzles.
But an idea on the matter by a Scottsdale City Council member fizzled last week.
People are pissed, Councilwoman Kathy Littlefield told the Progress a few hours before her attempt to get road diets on the next ballot failed.
Scottsdale residents, she said, are very very upset and they want more to say on this.
While supporters say sacrificing vehicle lanes for bike lanes makes driving safer for all, others have deluged council members with emails saying no more road diets!
Even if the issue never makes it to the ballot, Littlefield said she wanted a specific agenda item on road diets to invite public comment.
I want to lead a conversation so we can open it up to the citizens and they can have more say, Littlefield said, adding the April 17 open house on a Thomas Road diet plan left those who attended frustrated.
Im asking for a discussion on (road diets), Littlefield said. My guess is (her council colleagues) are not going to want to discuss it. Im going to give it a try because there are so many people that are so angry thats what were supposed to do, represent them.
As Littlefield predicted, her motion was rejected at the April 18 City Council meeting.
Mayor David Ortega and council members Tom Durham, Tammy Caputi and Solange Whitehead voted against Littlefields motion, over the support of Littlefield, Barry Graham and Betty Janik.
In discussion before the vote, Littlefield gave an introduction to her motion. She said that, contrary to previous staff reports promising road diets would be few and far between, there are now 15 street trimmings and more in the works.
Our citizens feel betrayed and they feel lied to, she said.
You should want the voters to decide this, Littlefield lectured her council colleagues. It is the only hope we have to restore the trust of our citizens.
Whitehead took a pointed jab stating Littlefield herself made a motion to approve a road diet on Indian School Road before emotionally decrying Littlefields motion.
Public safety is Scottsdales primary job. Its not up for a public vote. We dont ask the citizens what the speed limit should be its our job, Whitehead said.
Janik countered, This is at least worth a discussion.
Ortega said Littlefields motion was not necessary, as a work study on the issue has been requested for May 16.
As Littlefield was speaking about more traffic coming to Scottsdale, Ortega cut her off.
There will be a work study on all the details, Ortega said, calling for a vote.
Alex McLaren, during the public comment section of the council, called the Thomas Road open house a very good presentation.
But he called for an updated congestion report, as the one at the Thomas open house showed traffic patterns from 2016 to 2019.
Heather Phillips seconded that, saying the congestion numbers are pre-COVID and that in the Old Town area, skyrocketing rent prices are leading more residents to crowd into apartment units
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Idea of putting city's 'road diets' on ballot fizzles - scottsdale.org
LDP wins 4 of 5 Diet by-elections amid snap election speculation – Kyodo News Plus
Japan's ruling Liberal Democratic Party, headed by Prime Minister Fumio Kishida, secured four of the five Diet seats up for grabs in by-elections on Sunday, boding well for him amid speculation that he might dissolve the lower house in the near future.
The LDP won the Yamaguchi Nos. 2 and 4 districts and the Chiba No. 5 district in the House of Representatives as well as the Oita prefectural district in the upper chamber. Its candidate was defeated in the Wakayama No. 1 district in the lower house by a new face backed by an opposition party that has gained momentum recently.
The outcome of the polls, held about a week after an explosive device was thrown at Kishida during a campaign speech in Wakayama, may prompt him to call a snap election soon after the Group of Seven summit in his home constituency of Hiroshima next month.
Nobuchiyo Kishi (C) is pictured in Iwakuni, Yamaguchi Prefecture, on April 23, 2023, ahead of his likely win in a by-election for the House of Representatives Yamaguchi No. 2 district. (Kyodo)
Kishida's LDP had hoped to retain three seats in the first parliamentary elections since July last year, with the approval ratings for his Cabinet picking up on the back of his diplomatic achievements, such as a surprise visit to Ukraine on March 21.
After the LDP won in four districts, Toshimitsu Motegi, secretary general of the LDP, told reporters, "We have received a positive evaluation from the public."
The Yamaguchi No. 4 district used to be held by former Prime Minister Shinzo Abe, who was assassinated by a gunman during an upper house election campaign speech on July 8, 2022.
The LDP backed Shinji Yoshida, a former local city assemblyman, while the main opposition Constitutional Democratic Party of Japan fielded Yoshifu Arita, a former upper house member.
Shinji Yoshida (C) is pictured next to Akie Abe (R), widow of slain former Prime Minister Shinzo Abe, in Shimonoseki, Yamaguchi Prefecture, on April 23, 2023, ahead of his likely win in a by-election for the House of Representatives Yamaguchi No. 4 district. (Kyodo)
The Yamaguchi No. 2 district was previously held by former Defense Minister Nobuo Kishi, Abe's younger brother. But he retired for health reasons in early February, and his eldest son, Nobuchiyo Kishi ran in his father's place.
The Wakayama No. 1 district was up for grabs after a lawmaker of the opposition Democratic Party for the People resigned to become the prefecture's governor.
Former upper house member Hirofumi Kado ran on the LDP ticket, but he was beaten by Yumi Hayashi, who served as a local assembly member. Hayashi was backed by the Japan Innovation Party, which has a strong foothold in the Kansai region, including Wakayama.
The Japan Innovation Party has been aiming to expand its support base beyond the western Japanese region, and its Osaka base. The party more than doubled its seats in local elections in early April to 124.
Nobuyuki Baba, head of the party, told reporters in Wakayama on Sunday, "We have proven that even an ant can hurt an elephant if we work together in unity and solidarity."
The Chiba No. 5 district election was called after an LDP lawmaker resigned in December over allegations of underreporting political funds.
The LDP, which faced an uphill battle in the constituency against the backdrop of the political funds scandal, fielded Arfiya Eri, a former United Nations official of Uyghur descent. The major opposition parties failed to settle on a unified choice.
The upper house seat in Oita became empty after an independent lawmaker, who won the seat with the support of the Constitutional Democratic Party of Japan and other opposition forces, chose to run for the governorship in the prefecture.
Aki Shirasaka, an entrepreneur endorsed by the LDP, defeated Tadatomo Yoshida, a former upper house lawmaker of the Constitutional Democratic Party of Japan.
Voter turnout was the lowest on record for Chiba at 38.25 percent, while that in Wakayama stood at 44.11 percent. Turnout in the Yamaguchi Nos. 2 and 4 districts was 42.41 percent and 34.71 percent, respectively, and that in Oita 42.48 percent, the election boards said.
Voters are pictured at a voting booth in Oita, the capital city of Oita Prefecture on Japan's southwestern main island of Kyushu, on April 23, 2023. (Kyodo)
Earlier this month, a man hurled a cylindrical object that exploded and let out white smoke near Kishida in Wakayama, sparking a flurry of Japanese media reports ever since. The premier was not harmed in the attack.
Regarding policy, all eyes were on whether voters support the government's steps to reduce the adverse effects of rising prices and its plan to increase spending for defense and child-rearing measures, which have fanned fears about possible tax hikes.
Kishida's leadership, meanwhile, has been called into question over dubious ties between LDP lawmakers and the controversial Unification Church, in addition to a series of resignations by scandal-tainted ministers late last year.
Abe's attacker said he held a grudge against the religious group over huge donations made by his mother. He targeted Abe in the belief that the longest-serving prime minister of Japan had links to the organization, investigative sources said.
The latest polls were carried out on the same day as the second round of local elections held nationwide to select mayors and assembly members. The LDP won key gubernatorial races in the first round of the quadrennial unified local polls on April 9.
Under Japan's Constitution, a prime minister has the final say on the dissolution of the lower house for a snap election. The current four-year terms for lower house members expire in October 2025 unless Kishida dissolves the chamber.
Kishida, who took office in October 2021, has been exploring the best timing to win a general election, as he is eager to be re-elected as leader of the ruling party, pundits said. The next LDP presidential race is slated to be held in September 2024.
Related coverage:
Campaigning starts for mayoral, municipal assembly elections
Japan PM Kishida's ruling bloc wins key gubernatorial polls
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LDP wins 4 of 5 Diet by-elections amid snap election speculation - Kyodo News Plus
Uncovering the real paleo diet: Scientific team wins HFSP research … – EurekAlert
image:Dentition of a modern baboon (Papio ursinus). These savanna dwelling omnivores provide a prime analogous model for early hominin evolution. They evolved and radiated in parallel with hominins within a similar landscape and time frame. Tina Ldecke and her colleagues use tooth enamel from dentitions like this to develop the new method. view more
Credit: Tina Ldecke
Emmy Noether Group leader Tina Ldecke from the Max Planck Institute for Chemistry (MPIC) in Mainz, has been awarded a prestigious and highly competitive Human Frontier Science Program (HFSP) Research Grant along with Cajetan Neubauer from the University of Colorado Boulder (Institute of Arctic and Alpine Research) and Rani Bakkour from the Technical University of Munich (TUM).
The three-year funding, around U.S. $1 million in total, will support the international scientific team led by principal investigator Cajetan Neubauer to work on the project "Uncovering the real paleo diet: Novel isotope analytics of amino acids from fossil hominin teeth. The team aims to develop a new method to measure the isotopic composition of amino acids in tooth enamel and thus get more details on the hominin diet.
Much of our understanding of the relationship between hominin diet and evolution is based on anatomical and archaeological information derived from hominin fossils, explains Tina Ldecke.
Direct chemical evidence of paleodiets has also been measured, in fossil bone collagen and tooth enamel, in the form of stable carbon isotope patterns that are indicative of food intake. Proteins and amino acids are likely preserved in enamel even millions of years old and their isotopic compositions could provide specific insights into how ecosystem use and dietary changes in human prehistory shaped human biology, societies, and cultures. Unfortunately, currently no technique exists that can reveal paleodiet signatures from fossil amino acids. This is what we want to change with our funded project, she said.
The winners in this years HFSP Research Grant Program are remarkable scientists pioneering life science research that needs international collaboration and basic science in frontier subjects that is, investigations for which there are no prior studies, said Pavel Kabat, HFSP Secretary-General. I was thrilled with the proposals we received and look forward to the ground-breaking discoveries that will be revealed.
New Method explored
Our team hypothesizes that recent advances open a path to achieve the ultimate dream for the isotope approach to learning about human evolution: highly sensitive detection of intact fossilized metabolites and full description of the paleodietary information they record, says Cajetan Neubauer. This international grant brings together a team that has key complementary skills in analytical chemistry, isotope analytics, and paleoanthropology, says Neubauer.
Tina Ldeckes group has recently developed a method to analyze nitrogen isotopes in bulk tooth enamel to evaluate early hominin meat consumption for the first time. However, amino acids analyses are very desirable to clarify which animal resources were consumed (carnivores/herbivores), if fish or mushrooms were utilized, the role of breastfeeding, and if our ancestors hunted or instead scavenged. Most importantly, enamel amino acids could provide information about the use of fire, believed to be crucial for the evolution of large brains, as cooked foods provide much more energy than raw materials.
My team collects samples, i.e. teeth from hominins, but first of all from recent and fossil large mammals to develop and test the method and then to evaluate the results paleoarcheologically, Ldecke explains.
Molecular imprinting at TUM
Rani Bakkour and his team will then isolate very small amounts of amino acids from this enamel. The researchers from TUM have extensive expertise in environmental analytical chemistry, where they synthesize and evaluate highly selective materials for the extraction of aquatic contaminates. "We synthesize macromolecules that can recognize only one molecule at a time, a technique known as molecular imprinting," explains Bakkour. "We employ this technique to isolate minute amounts of contaminants such as glyphosate from complex mixtures." This method is particularly exciting in paleoanthropology. "Selectivity is a key given the very small amounts of amino acids in tooth enamel and the very small size of the precious fossil samples."
Novel isotope analysis at CU Boulder
Afterwards, Cajetan Neubauer will measure them subsequently with a newly developed isotopic technique (Iso-Orbi) in Colorado. What Neubauer has developed at CU Boulder is an innovative and powerful isotopic technique that brings isotope analysis into the realm of structural chemistry. It allows measurement of isotopic fingerprints in polar chemical compounds by electrospray-Orbitrap mass spectrometry. Iso-Orbi reveals the isotopic anatomy of amino acids and can thereby provide a wealth of new multi-elemental and structural isotopic information that we anticipate will be reflective of paleo diet and environmental factors.
Our goal is to develop a new way to look deeper into fossil molecules that will transform anthropology by exploring this emerging frontier, summarizes Tina Ldecke.
Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.
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Class of 2023 Outcomes: Lauren Dinkla Graduates with Courage – High Point University
HPU graduates are leading prestigious career paths around the world at Fortune 500 companies, international service programs, public school systems, top-tier law, medical and graduate school programs, and many other esteemed organizations thanks to their journey at HPU. Heres a glimpse at one extraordinary member of the Class of 2023:
Name: Lauren Dinkla
Hometown: Lisle, Illinois
Major: Exercise science with a minor in psychology
Post-graduation plans:Dinka will attend Wake Forest University in Winston-Salem, North Carolina, in the MS of Health and Exercise Science program.
How HPU helped you get there:
HPU provided me with hands-on experiences creating and conducting research with numerous faculty members since my freshman year. These diverse research experiences differentiated me from other graduate school applicants and prepared me for future research projects.
Most impactful mentor at HPU:
My most impactful mentor at HPU is Dan Tarara, chair and associate professor of exercise science. He taught me new research techniques in the Human Biomechanics and Physiology Lab as we created and tested our research study. He also opened my eyes to all the possible careers in exercise science which made me excited for graduate school and a future career in the field.
Most impactful moment at HPU:
My most impactful experience at HPU was living in Finch Hall where I met my best friends. Throughout my four years at HPU, I created memories I will never forget with my friends.
How has HPUs inspiring environment contributed to your success?
HPUs inspiring environment encouraged me to become involved as an anatomy tutor and clinic liaison at the Pro Bono Physical Therapy Clinic to reach my future goals. Every day at HPU I was surrounded by students and faculty who strive to become involved and succeed, which encouraged me to do the same.
What are the life skills HPU helped you develop that prepared you for long-term success?
HPU helped me develop creativity and innovation in my research projects and in my daily life. Through working with faculty members and students, I have developed an ability to search for the unknown and create innovative studies.
What are the values and virtues HPUs campus helped you develop that youll take with you after graduation?
HPU emphasizes having a growth mindset which helped me develop the tools to overcome any challenge I face.
Advice for underclassmen:
Be open to new career options in your desired field, and have the courage to reach out to current professionals.
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Class of 2023 Outcomes: Lauren Dinkla Graduates with Courage - High Point University
NFL PLAY 60 Fitness Break broadcast keeps kids active in advance … – American Heart Association
DALLAS, April 24, 2023 TheAmerican Heart Associationand theNational Football League(NFL), in collaboration with its 32 NFL clubs, are challenging kids to move more with an NFL PLAY 60 Fitness Break for the NFL Draft happening later this week. The free program on Wednesday, April 26 at 1 p.m. ET/ 12 p.m. CT/ 10 a.m. PT will offer a 15-minute synchronous broadcast to help students learn how to add movement to their day leading up to the live Draft coverage from Kansas City.
Rooted in American Heart Association science, the Fitness Break broadcast helps students learn more about how physical activity supports their overall wellness. The NFL Draft host team, the Kansas City Chiefs, will bring several members from the Chiefs Kingdom to the broadcast. NFL Legend Will Shields, Chiefs mascot KC Wolf and members of the Chiefs cheerleaders will get kids moving with exercise instruction. Local Kansas City high school student and congenital heart defect survivor, Devyn Davis, hosts the broadcast.Advanced registrationby parents, teachers or school administrators for the broadcasts is required.
NFL PLAY 60 initiative helps children to develop healthy habits for a better chance of a healthy adulthood. The program encourages kids to get a minimum of 60 minutes of vigorous physical activity each day to meet the U.S. Department of Health and Human Services 2018 Physical Activity Guidelines for Americans[1]. Reducing sedentary behavior and increasing physical activity are key to immediate and long-term health for children.
Working together with the National Football League on NFL PLAY 60, were excited to continue to support getting youth across the country moving towards a healthier and more active lifestyle, said American Heart Association and American Stroke Association Chief Executive Officer Nancy Brown. Wellness education and lifesaving skills, such as CPR, are critical to help people across generations live longer, healthier lives.
This is the third broadcast of the school year. The NFL PLAY 60 Fitness Break Kickoff broadcast was held in September and the NFL Super Bowl Fitness Break took place in February. There will be a new suite of NFL PLAY 60 resources, including Fitness Break Broadcasts, for the 2023-2024 school year.
Were excited to partner with American Heart Association for the NFL PLAY 60 Fitness Break ahead of this years NFL Draft especially when heart health and wellness is at the top of mind for the NFL family, said Anna Isaacson, NFL SVP of Social Responsibility. Providing free, educational resources to help youth lead a healthy lifestyle is a priority and the NFL PLAY 60 fitness break provides a fun and engaging way to do so.
In addition to the NFL PLAY 60 Fitness Break, the NFL and the American Heart Association will host an NFL PLAY 60 Play Space refurbishment project at Frank Rushton Elementary School in Kansas City. The PLAY 60 Play Space refurbishment project will help kids to get active and work towards their 60 minutes of daily physical activity.
Also, at the NFL Draft Experience in the days leading up to the game, April 27-29, attendees are invited to Be The Beat and learn Hands-Only CPR with the American Heart Association. During this engaging and interactive instruction, attendees of all ages will learn the two simple steps to help save a life and can try out skills.
For more information on NFL PLAY 60, visitheart.org/NFLPLAY60. For more information on CPR, visitcpr.heart.org.
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About the American Heart Association
The American Heart Association is a relentless force for a world of longer, healthier lives. We are dedicated to ensuring equitable health in all communities. Through collaboration with numerous organizations, and powered by millions of volunteers, we fund innovative research, advocate for the publics health and share lifesaving resources. The Dallas-based organization has been a leading source of health information for nearly a century. Connect with us onheart.org,Facebook,Twitteror by calling 1-800-AHA-USA1.
About NFL PLAY 60
NFL PLAY 60 is the League's national youth health and wellness campaign to encourage kids to get physically active for at least 60 minutes a day. Since PLAY 60 launched in 2007, the NFL has committed more than $361 million to youth health and fitness through PLAY 60 programming, grants and media time for public service announcements. Over the past decade, the NFL has partnered with leading academic, scientific and nonprofit organizations to help children of all abilities lead healthier, active lives. The NFL and its clubs have supported programs in over 73,000 schools and constructed more than 282 youth fitness zones nationwidegiving more than 38 million children an opportunity to boost their physical activity levels. NFL PLAY 60 is also implemented locally, as part of the NFL's in-school, after-school and team-based programs. For more information, visit NFL.com/PLAY60.
For Media Inquiries:
American Heart Association -Linzy Cotaya: 504-872-3446;linzy.cotaya@heart.org
For Public Inquiries: 1-800-AHA-USA1 (242-8721)
heart.organdstroke.org
NFL -Jordyn White:Jordyn.White@nfl.com
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NFL PLAY 60 Fitness Break broadcast keeps kids active in advance ... - American Heart Association
Support Services Give Parkinson’s Patients Healing and Purpose – Hackensack Meridian Health
For the 1 million people living with Parkinsons diseasein the U.S.shaking, stiffness, and difficulty walking and talking become a daily reality. Living well with this progressive neurological condition takes a village. But these inpatient and outpatient services can help patients better control symptoms and maximize their abilities.
What It Is: PingPongParkinson is a non-profit with local chapters that host weekly ping-pong exercise groups for people living with Parkinsons disease. It provides opportunities for physical, cognitive, and social engagement.
Why It Helps: Ping-pong (or table tennis) can help people with Parkinsons disease maintain their coordination and fine motor skills. The idea is based on the concept of neuroplasticity, the brains ability to make new nerve cells and connections through challenging exercise. Although medication remains the main treatment focus for Parkinsons, compelling evidence suggests regular exercise significantly helps manage the disease.
What It Is: A unique two-week inpatient rehabilitation program at JFK Johnson Rehabilitation Institute, the Parkinsons Wellness Program aims to help patients actively address any decline or required medication changes to enhance as much functionality as possible. After completing the inpatient admission, patients may transition to outpatient services that include the SPEAK OUT! and LOUD Crowd programs, which help patients regain voices dimmed by the disease by combining education, speech therapy, daily home practice and group sessions.
Why It Helps: The program empowers patients to develop and meet their own individual goals, which can range from scaling back medication dosages to avoiding falls, improving voice quality or just functioning better during daily activities. SPEAK OUT! Combines both education and one-on-one speech therapy, while LOUD Crowd promotes accountability, camaraderies and encouragement through group sessions.
What It Is: Rock Steady Boxing is a non-profit Parkinsons wellness exercise program that uses a surprising techniquenon-contact boxingto support people with Parkinsons disease. Its regimen was largely adapted from boxing drills, helping patients beat back the opponent with rigorous exercises.
Why It Helps: The exercises focus on improving speed, agility, hand-eye coordination, footwork and overall strength to empower people with Parkinsons and instill a renewed sense of hope.
What It Is: Through a Parkinsons Foundation community grant, JFK Johnson Rehabilitation Instituteoffers the ParkinSINGS choir that brings together Parkinsons patients for fun and vocal fitness.
Why It Helps: Parkinsons disease can weaken speaking and swallowing, but research shows that singing can help maintain the muscles involved in these key tasks. Plus, the choir also promotes camaraderie and social interaction.
What It Is: Hackensack Meridian Health runs support groupsat hospitals throughout the network that meet at various days and times. Some of the groups also meet virtually.
Why It Helps: Parkinsons patients, along with their caregivers, benefit from sharing their challenges and triumphs with others going through the same experience.
What It Is: Working with Abbott Laboratories, Hackensack Meridian Health uses a wireless app to remotely adjust electronic stimulation levels for patients who have undergone deep brain stimulation (DBS) surgery, which implants a pacemaker-like device in the brain to control tremors, stiffness and other Parkinsons symptoms. Another partnership, with medical device company Medtronic and Rune Labs, offers Parkinsons patients a free Apple watch if they use a Medtronic battery in their DBS device. With the Apple watch, patients can use motion-sensing software to better manage their disease by tracking aspects such as sleep, tremor frequency and abnormal movements that persist after medication use.
Why It Helps: At the touch of a button, these smartphone apps connect Parkinsons patients with information and resources that can help monitor symptoms and tweak certain therapies.
The material provided through HealthU is intended to be used as general information only and should not replace the advice of your physician. Always consult your physician for individual care.
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Support Services Give Parkinson's Patients Healing and Purpose - Hackensack Meridian Health
The Future of Corporate Wellness: Staying Ahead of Industry Trends … – Corporate Wellness Magazine
Corporate wellness programs have come a long way over the years, evolving from a simple perk to a critical strategy for many organizations. The pandemic has only accelerated this trend, highlighting the importance of employee health and wellbeing, especially in high-stress environments. However, as the field of corporate wellness continues to expand, it's important to stay ahead of the latest trends and innovations to create the most effective programs for employees.
One of the most significant trends in corporate wellness is the move towards a more personalized approach. Traditional wellness programs often adopt a one-size-fits-all approach, but this doesn't always work for everyone. Personalized wellness programs, on the other hand, use data and technology to create tailored programs that are specific to individual needs and preferences.
For example, some companies are using wearables to track employee activity levels and sleep patterns, and then use this data to develop customized wellness plans. Others are using genetic testing to identify individual health risks and develop wellness plans that specifically target these risks.
Another trend in corporate wellness is the focus on mental health. In the past, corporate wellness programs tended to focus primarily on physical health, such as nutrition and exercise. However, the pandemic has highlighted the importance of mental health, and many organizations are now incorporating mental health support into their wellness programs.
This might include offering access to therapy services, mindfulness and meditation training, and stress management programs. Some organizations are even using virtual reality technology to create immersive relaxation experiences for employees.
Another innovation in corporate wellness is the use of artificial intelligence (AI). AI can analyze large amounts of data to identify patterns and trends, which can then be used to create more effective wellness programs. For example, AI can identify common health risks among employees and develop targeted programs to address these risks.
AI can also be used to create chatbots and virtual assistants that can provide personalized wellness advice to employees. This allows employees to access support and guidance 24/7, which can be especially beneficial for remote workers.
In addition to these trends and innovations, there are some foundational principles that are essential for any effective corporate wellness program. First, it's important to create a culture of wellness within the organization. This means promoting wellness as a core value and encouraging employees to prioritize their health and wellbeing.
It's also important to make wellness programs accessible and inclusive. This means taking into account the diverse needs and preferences of employees and offering a range of options to suit different lifestyles and schedules.
Corporate wellness is an essential strategy for modern organizations. With the rise of remote work and the increasing prevalence of high-stress work environments, it's more important than ever for organizations to prioritize the health and wellbeing of their employees. However, creating effective corporate wellness programs can be a challenge, especially as the field continues to evolve and expand. In this article, we will explore some additional trends and innovations in corporate wellness, as well as some best practices for creating effective programs.
One important trend in corporate wellness is the focus on employee engagement. Traditional wellness programs often struggle to engage employees, with low participation rates and limited impact. However, by using creative strategies to engage employees, organizations can create more effective wellness programs.
For example, some organizations are using gamification to make wellness programs more engaging and fun. This might include using leaderboards to encourage friendly competition among employees or offering rewards for achieving wellness goals.
Another strategy for engaging employees is to create wellness programs that are integrated into the workday. For example, some organizations are offering on-site fitness classes or walking meetings to encourage physical activity. Others are offering healthy snack options in the office or creating designated quiet spaces for mindfulness and meditation.
Another trend in corporate wellness is the focus on sleep. While traditional wellness programs have often focused on exercise and nutrition, sleep is increasingly recognized as a critical component of overall health and wellbeing. Some organizations are offering sleep workshops or creating quiet spaces for employees to take power naps during the workday. Others are providing access to sleep tracking devices or offering sleep coaching services.
Another innovation in corporate wellness is the use of predictive analytics. Predictive analytics uses data and algorithms to identify health risks before they become serious. By analyzing employee data, such as health claims or biometric data, organizations can identify employees who may be at risk for chronic diseases or other health problems. This allows organizations to create targeted wellness programs that can help prevent these problems from occurring.
Finally, a best practice for creating effective corporate wellness programs is to foster a sense of community among employees. This means creating opportunities for employees to connect with each other and support each other in their wellness goals. For example, some organizations are creating wellness committees made up of employees from different departments, or offering team challenges that encourage employees to work together towards a common goal.
In conclusion, corporate wellness is a critical strategy for modern organizations. By staying ahead of the latest trends and innovations, organizations can create effective wellness programs that support the health and wellbeing of their employees. Additionally, by following best practices such as fostering a sense of community and focusing on employee engagement, organizations can create wellness programs that are not only effective but also enjoyable and sustainable for employees. If you are interested in learning more about how to create effective corporate wellness programs, the Corporate Health & Wellness Association offers the Certified Corporate Wellness Specialist program, which can provide you with the skills and knowledge you need to succeed in this field. You can find more information about this program at https://www.corporatewellnesscertification.com/.
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The Future of Corporate Wellness: Staying Ahead of Industry Trends ... - Corporate Wellness Magazine
New Strategies for Treating Parkinson’s Disease in Veterans … – UCSF Department of Radiology & Biomedical Imaging
Parkinson's Disease (PD) is a chronic and progressive movement disorder that results from the degeneration of dopamine-producing neurons in the brain. This leads to a range of motor symptoms, including tremors, stiffness and difficulty with balance and coordination, as well as non-motor symptoms such as depression, anxiety and sleep disturbances.
PD affects around 10 million people worldwide, with approximately 60,000 new cases diagnosed each year in the United States alone. Veterans are at a higher risk of developing this disease than the general population. Several factors contribute to the increased risk of PD in veterans, including exposure to environmental toxins such as Agent Orange and traumatic brain injuries (TBIs).
The diagnosis of PD is based on clinical symptoms, but imaging tests can help confirm the diagnosis. The most common imaging test used to diagnose PD is a dopamine transporter (DaT) scan, which involves injecting a radioactive tracer into the patient's bloodstream. Research is ongoing to find new biomarkers for the diagnosis of PD, and a recent breakthrough is thealpha-synuclein seed amplification assay( Syn-SAA), a biological test for PD. Syn-SAA demonstrates high diagnostic accuracy and differentiates molecular subtypes, offering a critical objective tool for clinical trial design, assessment of treatment effects and early detection of disease pathology for prevention.
PD is a complex disease with no cure, but there are treatments available that can help manage the symptoms and improve quality of life for those living with PD. One promising area is the development of new drugs that target specific molecular pathways involved in the progression of PD, such as drugs that target alpha-synuclein. Other researchers are exploring the use of immunotherapy to target misfolded proteins in the brain, which may offer a more focused and effective approach to treating PD.
In addition to these approaches, researchers are also exploring the potential of exercise and physical therapy to improve motor function and quality of life in PD patients. Some studies have suggested that regular exercise can slow the progression of PD and improve balance, gait and other motor symptoms. Other studies are investigating the use of virtual reality and other technologies to provide more engaging and personalized exercise programs for PD patients.
Research is ongoing to explore a wide range of strategies for potential treatment of PD in veterans and other populations. While there is still much to learn about the underlying causes and mechanisms of PD, these new approaches offer hope for improving the lives of those affected by this debilitating disease. It is essential to continue to raise awareness about PD, support research efforts, and provide better resources and care for those living with PD and their families.
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