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Realme launched the seemingly pointless Realme 5i smartphone in India yesterday but the one thing that we seemed to have missed during the soft-launch was CEO Madhav Sheth teasing viewers a glimpse of the rumored Realme fitness band.

During the product presentation Sheth took the fitness tracker out of his pocket and slapped it on his wrist. A pretty shameless plug no? A pretty smart plug nonetheless.

The yellow colored band is seen wearing a signature hue of Realme and is seemingly rectangular in shape. Earlier in December 2019, Sheth, during an episode of Ask Madhav (a periodical AMA series on YouTube), revealed the company's plans to foray into the lifestyle segment with its fitness band.

SEE ALSO: Mi Band 4 Review: A Great Fitness Tracker For You & Your Wallet

The Realme fitness tracker will go up against the likes of Xiaomi Mi Band 4 and Honor Band range. As a result, we also believe that it will also be priced aggressively. However, it remains to be seen if the fitness tracker from Realme will use a colour display like the Mi Band 4 or a monochrome one.

While Sheth did not reveal a specific date as to when the company will launch this fitness band, he did state that we can expect it "soon". Earlier, Sheth had said in the AMA that the fitness tracker will be launched in the first half of 2020 but understandably, didn't specify a launch date.

More intricate details about the Realme fitness tracker such as the sensors, connectivity, UI, health monitoring features remain unknown. Having said that, we expect the company to reveal more details about the fitness tracker gradually in the heads up to the launch.

Yesterday's launch event also saw Realme launch a new blue colorway for its recently launched truly wireless earphones. That was alongside a new Realme sweatshirt for die hard fans of the brand.

SEE ALSO: Realme's Fitness Tracker To Launch In 2020; Will Compete With Xiaomi Mi Band 4

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Realme Fitness Band Teased By CEO Madhav Sheth During Realme 5i Launch - Mashable India

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The Victorian era is often remembered as an age of industrial innovation, staunch morals and hard work. When we imagine the stereotypical Victorian, we often picture stiff collars and heavy, head-to-toe dresses not celebrity weightlifters or homemakers practising callisthenics. But it turns out our obsession with physical fitness isnt just because of 20th-century stars like Jane Fonda, Arnold Schwarzenegger, and Dwayne The Rock Johnson. In fact, the Victorian age saw the beginnings of modern celebrity fitness culture and new forms of exercise which we might credit for our current obsession today.

The Victorian fitness craze might first be traced back to the publication of Donald Walkers book British Manly Exercises in 1837. The book included diagrams showing proper rowing technique, horse-riding instructions and detailed guidance on how to lunge, vault and wrestle. Walker also included exercises borrowed from different cultures, such as strength training using clubs from India which offered the most effectual kinds of athletic training known anywhere, according to a British officer stationed in the country. These forms of exercise quickly became popular, often because they were adopted by the British military.

Achieving physical fitness gradually became a cornerstone of Victorian values. This was largely inspired by cultural trends such as Muscular Christianity, which originated in England in the mid-19th century. Muscular Christianity emphasised the importance of training the body to reflect devotion to both God and society.

One author claimed that strong Christian bodies could be used to protect the weak, advance all righteous causes, and promote the subduing of the earth which God has given to the children of men.

Although hobbies such as riding horses and playing golf remained popular with the upper class, exercise done at home became increasingly favoured by the emerging Victorian middle class. The Portable Gymnasium became a bestseller after it was published in 1861. It claimed there were numerous benefits to undertaking what the author called gymnastic exercises, which were said to develop and restore the human form. Some of these exercises look similar to what wed do today. Readers were instructed to use the portable gymnasium to perform body-toning exercises such as lateral extensions and head rotations.

Exercise had grown so popular that by 1865, the Royal Patent Gymnasium a huge outdoor gym was opened in Edinburgh. It regularly attracted thousands of fitness fanatics each day. It featured The Giant Sea Serpent, an enormous circular rowing machine which could reportedly seat 600 people at a time.

By the late 19th century, James Cantlie, a Scottish medical practitioner, had developed new exercise regimes that could be done at home. These included an elaborate routine of stretches to be performed morning and evening accompanied by bathing and muscle massage.

Cantlie argued that they were especially suitable for the over-50s as they did not cause too much exertion. He also founded the British Institute of Physical Training in 1889, where men and women, young and old, could attend exercise classes where they would practice Cantlies so-called physical jerks rhythmic movements to strengthen and tone the body.

People who came to the classes were encouraged to practice the exercises at home on a daily basis but were simultaneously warned they needed to return regularly to learn new exercises and ensure they were using the correct techniques. Cantlie also made other lifestyle recommendations, such as insisting that wearing kilts promoted the health and strength of lads as they didnt restrict the bodys natural movements.

Cantlies system was just one among many other competing exercise regimes. However, his system served as inspiration for the daily exercise regime members of the Outer Party were required to do in George Orwells 1984 more than half a century later.

Other popular approaches to fitness and health included a regime developed by one Dr E H Ruddock, whose book Vitalogy (1899), promoted good posture, vitativeness (love for life), and only moderate exercise to avoid overtiring the body.

The Victorian age also saw the rise of the celebrity fitness guru. At the end of the 19th century, one of the most famous was German-born Eugen Sandow. Sandow staged elaborate strongman shows throughout Europe and America and built up a global publishing empire through his magazine Physical Culture, which included profiles and images of bodybuilders and articles on the merits of different exercises. He credited his approach to exercise, built around dumbbell training, with transforming his physique and recreated poses from classical Roman and Greek sculpture to showcase his body.

Sandow was a trailblazer who inspired others, including the American bodybuilder Bernarr Macfadden. Just a year younger than Sandow, Macfadden claimed that he was weak and sickly as a child. He argued in his first book, Macfaddens Physical Training, which was published in 1900, that through a carefully managed vegetarian diet and regular weightlifting, anyone could overcome ill health, just as he had done. His system had specific guidance for young men, young women, middle-aged men and middle-aged women, and appropriate exercises as the years wane, all to be performed at home using his simple stretching device.

After a series of military setbacks, Britain was gripped by a sense of anxiety by the end of the Victorian era about its place in the world. Many worried that industrialisation which had driven the expansion of the British Empire had made bodies weak. British people feared that they had become trapped indoors in factories and offices, made slovenly by technological change. Worry about national fitness persisted into the early 20th century, and the exercise craze showed no signs of stopping.

For many middle- and upper-class Victorians, having a healthy body was an expression of religious and national devotion. Being able to achieve it in the comfort of the home was a bonus. The Victorian obsession with celebrating athletic prowess and striving to better their bodies physically is not unlike societys obsession with fitness today.

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Fitness gurus and 'muscular Christianity': how Victorian Britain anticipated today's keep fit craze - The Conversation UK

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That means exercisers both newbies and seasoned pros are hitting the trails and filling the gyms.

But when that new fitness program you're itching to try says to check with your doctor first, do you really need to?

If you're young, in fairly good health and aren't too far removed from your last exercise regimen, it might be OK if you skip the doc. But it's always a good idea to check, said Dr. Michelle Benes, a family physician with CHI Health.

"As people get older and the longer it's been since they exercised, it probably is a good idea to come in and make sure they're starting on an exercise program that fits their health status," Benes said.

Doctors will look for issues with blood pressure, heart murmurs, abnormal pulse, swelling in the legs and signs of asthma, Benes said.

It's also a good time to look for any underlying illnesses. Some issues, such as asthma, might be exacerbated by certain workouts. Other conditions, like nerve disease, might cause balance issues, heightening the risk for falls.

Exercise might improve other conditions, Benes said. Fibromyalgia sufferers will find they do well with warm- water workouts. People struggling with back pain can be guided toward exercise targeting the core and abs rather than heavy weights.

Benes suggests bringing up fitness routines at an annual physical. Doctors then can discuss other health factors, such as diet, sleep, alcohol consumption and screen time.

To start, she recommends that people consider a simple walking program. Cycling or aerobics might be too much out of the gate, and that could lead to injuries.

"Starting slowly is a better option if you decide to get into any exercise program," she said.

It's important that gym-goers share any chronic or underlying illnesses with trainers when working out, too. The trainers then can tailor a workout to best benefit the individuals.

For example, someone with arthritis might share which joints bother them. Then they can work to strengthen the muscles around those joints rather than putting more stress on the joints.

Benes offered the following tips to people getting into new workout routines:

Float spas, where users are suspended in a salty bath, started popping up in Omaha in 2016. Spa-goers enter a private float tank nearly double the size of a bathtub. Hundreds of pounds of Epsom salt have been dissolved in the shallow pool of water so people float on top. Proponents say floating reduces muscle and joint pain, shortens recovery time from athletic training or injuries, relieves stress and increases creativity. Click here to read a World-Herald story on float spas.

If you've been dreaming of dribbling a soccer ball while encased in a plastic bubble, you're in luck. That trend made its way to Omaha in 2015. The game can be tough experienced players tumble right alongside first-timers.Click here to read a World-Herald story on bubble soccer.

Local yogis can find their flow among a tribe of baby goats. Two dairies in Honey Creek, Iowa, started offering the classes in 2018. The goat yoga trend started in Oregon in 2016 and has since swept most of the country. The wandering goats add some levity to yoga, known for improving flexibility and decreasing stress. Click here to read a previous World-Herald story on goat yoga.

Kickball isn't just for kids. Adult kickball leagues have joined the mix of recreational sports in Omaha, much like sand volleyball and softball. The sport gets players moving, but it doesn't feel like a grueling workout. Some kickballers called it "exercise in disguise." Click here to read a World-Herald story on kickball.

Ballet-inspired workouts made their way to the Omaha area back in 2014. The city is home to handful of studios purely devoted to the workouts, which combine yoga, Pilates and ballet movements performed on a dance barre. Some local gyms and fitness studios offer the classes, too. Instructors said the classes are fun and motivating.Click here to read a World-Herald story on barre.

Rowing isn't new, but it's made a splash on the local fitness scene. The exercise machines had fallen out of favor thanks to treadmills, weight rooms and group exercise classes. But they've been reintroduced through fitness trends like CrossFit and Orangetheory. At least two local studios have debuted classes built around the machines. Click here to read a World-Herald story on rowing.

Participants wearing minimal clothing stand in a chamber that looks like an aluminum can and grows colder over two to three minutes using liquid nitrogen. The temperature drops to between negative 200 and 240 degrees. Proponents say the high-tech ice baths reduce inflammation, relieve pain, prevent injury, increase energy and speed healing. The practice also has been credited for cosmetic benefits. But some medical professionals are skeptical.Click here to read a World-Herald story on cryotherapy.

Exercisers bask in glowing orange lights and blaring upbeat music at Orangetheory Fitness. The metro area now is home to a handful of the studios, which got their start in Florida in 2009. During the classes, a trainer leads people through a circuit-style workout that rotates between treadmills, rowing machines and a strength area with free weights. Members wear heart rate monitors to track their efforts during a workout. Click here to read a World-Herald story on Orangetheory Fitness.

Pound classes debuted in Omaha in 2015. The classes are a full-body strength and cardio workout that simulates drumming. Exercisers pound the drumsticks in the air, against each other and on the ground while performing strength exercises like squats and lunges. Click here to read a World-Herald story on Pound.

Aerial yoga blends yoga poses with acrobatics. Yogis practice in hammocks, flipping upside-down. It incorporates stretching and strength exercises, cardio and meditation. Instructors say the class is good for the spine, alleviating pressure although there are some risks, and the class isn't for everyone. Click here to read a World-Herald story on aerial yoga.

Heart rate monitors are a standard part of curriculum for some metro high school students. They've also made an appearance in several boutique gyms. Teachers at Mercy High School said wearing the monitors prep students for a lifetime of fitness. Click here to read a World-Herald story on the monitors.

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Consider checking with a doctor before starting that new year's fitness plan - Omaha World-Herald

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The biggest show in consumer tech is on right now. Catch up on our highlights and follow us on Instagram for up-to-the-second coverage!

On the surface, technology and fitness might not seem closely tied, but as the quest to live our best physical lives rolls on, the two worlds become inextricably linked. Nowhere is this connection more apparent than at the annual Consumer Electronics Show in Las Vegas, where brands unveil their latest efforts to help us get healthier and fitter. Some of the ideas are just fine, some are goofy and some are ahead of their time, but they all combine to move us forward. The following six tripped our sensors, for one reason or another, at this years show.

Its not the first smart helmet to hit the market, but we dig the fact that LIVALLs brain bucket offers a ton of handy tech while looking pretty streamlined and cool. Standout features include front and rear lights activated by built-in gravity acceleration sensors, turn signals controlled via a handlebar remote and walkie-talkie functionality to aid communication when riding with a group.

Weve gotta give NURVV points for creativity here. The brand has embedded 32 precision sensors into a pair of insoles with the goal of helping runners improve their form to go faster and risk less injury. The sensors capture data 1,000 times per second and pair with an app to provide realtime feedback on factors like cadence, step length, footstrike, pronation and balance. At 250 ($327), they are pricy, but who knows? Maybe a big running shoe company will buy the tech and start integrating.

Assuming you can get used to sleeping with a giant headband, this streamlined update to the original Deep Sleep Headband promises to make sleep more restorative by triggering quiet audio tones that boost the quality of slow wave sleep (a.k.a. deep sleep). Theres also an app-paired sleep tracker (of course), and Philips says 80 percent of testers report positive results within two weeks of use. And thats not even including the bonus feature: we cant imagine this thing stirring anyones ardor, so it doubles as birth control!

File GEMS (Gait Enhancing & Motivating System), unveiled in 2019, under ahead of its time. The exoskeleton was designed to provide walking assistance and/or resistance, but Samsung rolled it back out this year as a potential home workout device, complete with a holographic personal trainer. Were not quite ready to strap on this harness, a pair of AR glasses and a Galaxy smartwatch just to do lunges, but it lays the groundwork for more feasible options down the road.

Suunto consistently makes burly and reliable sports watches, but as our own Oren Hartov noted in a story yesterday, the Suunto 7 is a bit of a departure. This watch seeks to blend sports watch functionality (offline maps, 70+ sport modes, GPS tracking) with a more accessible, lifestyle-y aesthetic (customizable faces, interchangeable straps) that wont look out of place with a suit or at least a blazer. So far, so good.

Finally, a Fitbit for dogs!

Steve Mazzucchi is Gear Patrols outdoors and fitness editor. Outside the office, you can find him mountain biking, snowboarding, motorcycling or sipping a dram of Laphroaig and daydreaming about such things.

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The Best Fitness Tech Innovations of CES 2020 - gearpatrol.com

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The quantification of performance has become a critical aspect of training and performance optimization for athletes, who have relied on performance quantification technologies to fine tune their performance, understand how to push harder, and when to pull back to avoid injury.

TORONTO (PRWEB) January 10, 2020

Myant Inc., pioneers in Textile Computing, will be exhibiting at CES 2020 in Las Vegas and showcasing a system of connected performance apparel (including a pair of connected cycling shorts) designed to augment fitness experiences, connecting athletes to their bodies, their training partners and coaches. Connected fitness represents just one facet of a life connected through textile that Myant is creating. These garments along with other connected textile form factors are poised to change the way people across society work, care for each other, and play.

The quantification of performance has become a critical aspect of training and performance optimization for athletes, and for cyclists in particular who have relied on performance quantification technologies to fine tune their performance, understand how to push harder, and when to pull back to avoid injury. The objective quantification of performance also serves as a motivational tool, helping to demonstrate progress over time and versus the competition. While many such tools exist, the individual measurement tools are often difficult to swap between bikes and the data generated from various tools are locked in their own platforms making it difficult to obtain a holistic view of performance.

Recognizing these challenges, Myant has been applying their expertise in textiles that can sense and react to the human body and is developing a line of fitness & performance apparel that consolidates numerous performance measurement tools into a single textile-based measurement platform. Different textile form factors (e.g. sports bra, underwear, sweat band, compression tights, etc.) all will have the ability to contribute data towards building a holistic picture of your performance and provide deeper context and understanding on how your broader life off the field (i.e. your sleep, your daily activity, etc.) is impacting your performance on the field. One such garment in development is a pair of connected cycling shorts with EMG sensors knitted directly into the textile which in combination with data captured by other connected garments (such as the connected athletic shoe or ECG shirt) enables access to a variety of performance metrics like fatigue, power output and blood/muscle oxygenation.

Other potential capabilities that can be integrated into fitness & performance apparel include posture detection and haptic feedback to correct form, heart rate via continuous ECG monitoring, respiration monitoring, blood pressure tracking, electrolyte-level monitoring via sweat sensing, activity tracking, electronically-controlled moisture management, and more. The cycling shorts and other fitness & performance interfaces will be on display in Myants booth at CES 2020, happening January 7th to 10th in Las Vegas.

The data generated by these textile-based sensors will be fed to the Myant Platform which aggregates these different data types to provide a single holistic view of your fitness & performance. Using machine learning on the Myant Platform, users will also be able to identify and predict performance issues, unlocking a new level of optimization. The insights derived from this data can be shared back to the athlete but also shared with training partners and coaches to augment the training experience. Training partners can share their data via apps connected to the Myant Platform, providing the social motivation to improve and push through.

The optimization of performance through connected textiles is just one of the many possibilities enabled by the Myant Platform, which provides a continuous and ambient connection between people and their bodies, their communities, and their environments across all aspects of daily life (i.e. home, work, and play). Myants presence at CES 2020 was designed to encourage others envision these possibilities, inspiring the world to challenge the way they see everyday textile and to reimagine the value that these objects can provide. Myant invites you to visit their booth at CES 2020 (Booth #43925, Sands Expo, Health & Wellness) to discover more about a world connected by textile.

For more information or to schedule a meeting with Myant at CES 2020, please contact:Brian FungMarketing Strategist at Myantbrian.fung@myant.ca, 416-423-7906 x401

Frank FlorioVP, Strategy & Business Development at Myantfrank.florio@myant.ca, 416-423-7906 x421

About Myant Inc.Myant has created the worlds first platform that continuously and ambiently connects people to their bodies, to each other, and to the world around them. Using connected textiles that can sense and react to the human body and a platform that enables machine learning driven health and performance outcomes, Myant is on a mission to transform human connectedness. With an extensive patent portfolio, key exclusive relationships within the textile computing industry, a multidisciplinary team of researchers, engineers, data scientists, fashion designers and knitting specialists, and over 80,000 ft of manufacturing capacity, Myant is changing the way people across society connect. Connect with us to find out how we can help you create innovative solutions powered by connected textiles and the Myant Platform.

Visit https://www.myant.ca to learn more.

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Myant to Demonstrate Connected Textiles for Fitness and Cycling at CES 2020 that Enable New Modes of Textile-Based Performance Optimization - PR Web

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Olly Mann and The Week delve behind the headlines and debate what really matters from the past seven days.

In this weeks episode, we discuss:

Testosterone levels have been in decline for some time, and a long-term study published this week in the Journal of Sexual Medicine reveals the extent of the phenomenon: men aged between 15 and 39 now have 25% less testosterone than men of the same age in 1999 - a huge drop in just 20 years. Many theories have been put forward, including diet, lifestyle, underwear trends and even social attitudes towards masculinity. But why testosterone levels are dropping - and what the end result might be - remains a mystery.

An employment tribunal has ruled that ethical veganism is a philosophical belief akin to a religion that is protected by law against discrimination. But could the verdict come back to bite the growing movement? And which other beliefs are or should be safeguarded by our courts?

East Africa is in the grip of the most severe swarms of locusts in over 70 years, threatening food supply to millions across Somalia, Kenya and Ethiopia. With climate change fuelling their breeding and governments asleep at the wheel - are we all doomed to face more plagues in the future?

You can subscribe to The Week Unwrapped on theGlobal Player,Apple podcasts,SoundCloudor wherever you get your podcasts. It is produced by Sarah Myles and the music is by Tom Mawby.

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The Week Unwrapped podcast: Testosterone, vegans and locusts - The Week UK

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Newswise SALT LAKE CITY In the first-ever genome-scale analysis of the puberty process in humans, researchers at Huntsman Cancer Institute (HCI) at the University of Utah (U of U) outline distinct and critical changes to stem cells in males during adolescence. They further outline how testosterone, and the cells that produce testosterone, impact stem cells in male reproductive organs. The researchers believe this study adds dramatically to a foundation of knowledge that may yield insights into critical areas of human health, including infertility and cellular changes that lead to cancer and other diseases.

The study, published today in the journal Cell Stem Cell, was led by Bradley Cairns, PhD, cancer researcher at HCI and professor and chair of oncological sciences at the U of U, in collaboration with colleagues Jingtao Guo, PhD, a postdoctoral fellow in the Cairns lab at HCI, James Hotaling, MD, associate professor of surgery at the U of U, and Anne Goriely, PhD, associate professor of human genetics at the University of Oxford.

Puberty spurs numerous developmental changes in humans and other mammals. Hallmarks of puberty include physical characteristics easily visible to the naked eye, like rapid growth. These physical and hormonal changes signal the process of a maturing body preparing for reproductive years.

In the testis, the male reproductive organ that makes and stores sperm and produces testosterone, puberty introduces monumental changes at a cellular and physiological level. Thanks to new genomic technologies, researchers are able to examine the expression of thousands of genes in each individual cell in an entire organ, providing unprecedented insights into cellular behavior during puberty.

Several types of cells within the testis regulate reproductive health. Like the human body that changes along the path from infancy to adulthood, these cells undergo major changes as the body matures. These cells include spermatogonial stem cells that ultimately generate sperm production, and niche cells that help form parts of the testis, such as the seminiferous tubule, a tube-like structure within which sperm is formed. In this study, researchers characterized how, just prior to puberty, spermatogonial stem cells first expand significantly in number. These stem cells progress toward meiosis, a special type of cell division that splits the number of chromosomes from the parent cell in half, and also separates the male X and Y sex chromosomes to create cells that, after fertilization of eggs and considerable subsequent development, will ultimately result in either male (Y-containing) or female (X-containing) children. Late in puberty, these stem cells commit to creating mature sperm, which includes a tail piece for motility. The researchers showed how two of the cells that form the stem cell niche and chaperone this processthe myoid cells and Leydig cellsderive from a common precursor, and mature during early puberty.

A major novel insight of this study was the first-ever genomic analysis of the testis of adult transfemales (individuals assigned male at birth, but who self-identify as female). For these individuals, gender confirmation surgery is preceded by hormone therapy that induces long-term testosterone suppression, enabling the examination of testis lacking testosterone. By using samples donated after surgery, researchers uncovered critical insights into the role of testosterone in maintaining testis development. Genomic analysis of the cells from the testis of transfemales showed that stem cells and other cells revert to earlier states of development when compared to samples from male adolescents. Thus, Cairns and his colleagues identified that testosterone is critical to maintaining the mature state of the testis: if testosterone is no longer present, the testis reverts to an earlier developmental state.

The major changes that occur in humans during puberty give rise to numerous functions in normal development, like reproductive health and fertility. But, when these processes go awry, confounding challenges can result. Infertility is a relatively common health issue. About 50 percent of the time, the underlying cause is attributed to the male reproductive functions, which often include errors that occur during puberty. The team hopes these insights into how cells develop will help yield insights into what happens when developmental issues during puberty cause changes that result in infertility.

The study also informs understanding of cancer and other diseases that arise due to errors in cellular processes. The majority of the time, testicular cancers arise when stem cells in the testis are misregulated, said Cairns. We want to understand how these changes can cause testicular tumors; however, we need to know what should normally happen before we can identify ways to prevent or more effectively treat these cancers.

In juveniles, cancers and reproductive health intersect via a medical process called oncofertility; that is, the study of how to retain fertility in adolescent and young adult cancer patients whose reproductive health and fertility may be impacted by their cancer, or as a result of side effects of cancer treatment. Some chemotherapies can result in young men with cancer not being able to have childrenthe chemotherapy can cause changes to their stem cells, said Cairns. My hope and expectation is that our research will provide a foundation for creating options to support the reproductive health of young men affected by cancer through a better understanding of how these stem cells survive, are supported, and develop.

This research was supported by the National Cancer Institute grant P30 CA042014, the Howard Hughes Medical Institute, and Huntsman Cancer Foundation.

###

About Huntsman Cancer Institute:

Huntsman Cancer Institute(HCI) at theUniversity of Utahis the official cancer center of Utah. The cancer campus includes a state-of-the-art cancer specialty hospital as well as two buildings dedicated to cancer research. HCI treats patients with all forms of cancer and is recognized among the best performing cancer hospitals in the country by U.S. News and World Report. As the onlyNational Cancer Institute (NCI)-Designated Comprehensive Cancer Centerin the Mountain West, HCI serves the largest geographic region in the country, drawing patients from Utah, Nevada, Idaho, Wyoming, and Montana. More genes for inherited cancers have been discovered at HCI than at any other cancer center in the world, including genes responsible for hereditary breast, ovarian, colon, head, and neck cancers, along with melanoma. HCI manages theUtah Population Database, the largest genetic database in the world, with information on more than 11 million people linked to genealogies, health records, and vital statistics. HCI was founded byJon M. and Karen Huntsman.

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First-Ever Genomic Study of Puberty Yields Insights into Development, Cancer, and Infertility - Newswise

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How men can help women advance in the workplace

Businesses thrive when both genders are represented at the top of their companies, according to studies. But in order for women to achieve parity, men need to help women succeed in their careers, according to Forbes contributor and leadership professor Susan Madsen. She recommended that men fight gender discrimination in the workplace, recognize womens contributions in public and private settings, provide honest feedback and refine human resources processes and procedures.

States weigh measures to stop transgender athletes from competing in womens sports

In the past few weeks, at least five states have drafted legislation to regulate transgender participation in girl's and boys high school sports. Republican legislatures in New Hampshire, Washington, Georgia, Tennessee and Missouri have drafted bills primarily to bar transgendered students from playing on girls teams, citing physical unfairness. The bill in New Hampshire says that students can prove they are female by submitting proof of their female anatomy, testosterone levels and sex chromosomes.

Fired at 40, comeback at 54, how Ellen Latham built fitness giant Orange Theory

At age 40, Ellen Latham had a dream job as an exercise physiologist at a high-end spa. She appeared on TV frequently as a fitness expert. Then one day, she was fired. She was a single mom and had no idea what to do next. Fourteen years later, she became the founder of Orangetheory Fitness, a $1 billion franchise with 1,200 studios around the globe. Know Your Value interviewed Latham to learn about her drive, her comprehensive workout, and the new documentary Momentum Shift, which chronicles the rise of Orangetheory.

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Raising my sensitive child was hell. Heres how we both survived her SPD, anxiety, and ADHD

There is hope for parents who are raising special needs children and having a difficult time. Thats the message from mother Jo Lomeo-Allen, who wrote a heartrending essay about raising her daughter who has ADHD, Sensory Processing Disorder, and Generalized Anxiety Disorder. Lomeo-Allen detailed her quest for diagnoses and treatment as her daughter threw hours-long tantrums over small things, such as a Cheerio dropping on the floor. Lomeo-Allen offered hope to parents and detailed her daughters road to stability.

Michelle Williams tells women at Golden Globes to vote in their self-interest, like men

Actress Michelle Williams didnt miss a chance to send a message during her Golden Globes acceptance speech Sunday. After accepting the award for Best Performance by an Actress in a Limited Series or Television Movie for her role in Fosse/Verdon, Williams encouraged women to vote in their own self-interest. So women, 18 to 118, when it is time to vote, please do so in your own self interest," Williams said. "It's what men have been doing for years which is why the world looks so much like them. Don't forget we are the largest voting body in this country. Let's make it look more like us."

How to stop stress-eating your way through the 2020 election

The upcoming election is a stress trigger for 56 percent of American adults, according to the American Psychological Association. Many of these adults overeat in order to cope with their stress. Clinical psychologists recommend that stress eaters take me time and limit their access to media. They suggest deep breathing, being social, and going for fruit instead of high-fat products.

All the celebrities who announced theyre expecting babies this year

Cameron Diaz, 47, announced the birth of her daughter Raddix on Friday. Other celebrities are following suit and announcing 2020 due dates, including actresses America Ferrera, Chloe Sevigny and Michelle Williams, according to Glamour. Others include U.S. Womens Soccer star Alex Morgan, actress Anne Hathaway, Laura Prepon from Orange is the New Black, and supermodel Petra Nmcov.

Black Britons know why Meghan Markle wants out

In the wake of Meghan Markle and Prince Harrys historic exit from the British royal family, Markle was called selfish and rogue by British press. However, writer Afua Hirsch argued that it was racism that pushed Markle and Prince Harry out of Buckingham Palace. Markle was the subject of extreme, unfair vitriol, which Hirsch believes is rooted in Britains history of class privilege, and the rising right-wing politics in the country.

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In the know: Women in the news 1/6 - 1/10 - NBC News

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When a non-scientist tries to imagine a scientist, the image that often arises is one of a somewhat remote, rather idealistic genius sitting alone in their room or laboratory and somehow discovering the most amazing things without every having contact with the 'normal' world. But science is just as much a part of life as any other activity. So it's perhaps not all that surprising to learn that - just like in normal life - intuition can occasionally play a major role in scientific progress.

The importance of intuition was made very clear to Professor Samer Ezziddin and his team at the Department of Nuclear Medicine at Saarland University when they followed up on findings made during their medical research work into the treatment of patients with late-stage prostate cancer. The work centres around two receptors on the surface of the tumour. The first is known as prostate-specific membrane antigen (PSMA), a protein molecule that is very prevalent on the surface of prostate tumours. This surface receptor molecule acts as a gateway and provides a channel through which nuclear radiologists can smuggle radioactive substances into the tumour cells and thus destroy these malignant cells from the inside. The more PSMA molecules on the surface, the more radioactivity can be introduced into the cells without needing to increase the total dosage of radioactive substance being administered to the patient.

The second type of receptor is one that male sex hormones, such as testosterone, are able to dock onto. 'Prostate tumours need testosterone like a car needs petrol,' explains Professor Ezzidin. So one of the therapies used to treat prostate cancer involves blocking these receptor sites, which effectively stops the cancer from refuelling. 'One of the drugs used to block these receptors is enzalutamide and enzalutamide therapy is often very successful for a certain period of time, during which the tumour shrinks,' says Samer Ezzidin. 'But after a while - which might be several months, perhaps even two years if things go well - the drug stops working and the tumour starts to grow again.' Typically, the patient will then be taken off the expensive medication, as there would seem to be no reason to continue to administer it if it's no longer effective.

This is where the intuition of the Homburg research team comes to the fore. What may be of no use for one type of therapy (an ineffective drug) might turn out to be beneficial in another form of cancer therapy. 'We suspected, and later on we showed quite definitively, that the density of PSMA sites on the surface of the tumour cell increases when the adrogen receptor to which testosterone attaches is blocked,' says Ezzidin. The gut feeling within the research group, combined with the group's clinical observations, strongly suggested that this mechanism would still function in patients for whom the receptor-blocking drug (enzalutamide) was no longer itself therapeutically effective and was therefore no longer being prescribed.

The intuition of the medical research team proved to be spot on. 'We were able to prove that administering enzalutamide resulted in a significant increase in the PSMA density on the tumour surface, even though the drug was no longer effective in its original therapeutic sense and was no longer being prescribed for that purpose,' explains Samer Ezzidin. Despite the fact that only ten patients were involved the study, Professor Ezzidin believes that the results are compelling. 'After administering enzalutamide, we observed a significant increase in PSMA density on the tumour surface in all patients in the study. This allows us to introduce far more of the radioactive therapeutic agent into the tumour cells and thus irradiate them from the inside with irradiation paths that are down at the micrometre level,' says Ezzidin. As a result, PSMA radioligand therapy will be able to treat prostate tumours more efficiently and more selectively than has been possible in the past (see the following report for more details: https://www.eurekalert.org/pub_releases/2019-11/su-pcr112519.php).

'These findings now need to be subjected to further study and corroborated in a future research project,' explains Professor Ezzidin. 'But we wanted to publish our results as quickly as possible, as our findings may be of help to lots of patients. That's why we decided to first issue this short communication. I expect that even this small-scale study will lead to a drastic change in the therapy management regimens used when treating patients with advanced prostate cancer,' says Samer Ezzidin. And it's very likely that Professor Ezzidin's intuition will once again turn out to be right on the mark.

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Nuclear radiologists 'outsmart' prostate cancer with an apparently ineffective drug - Science Codex

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Testosterone Replacement Therapy Market Business Status, Industry Trends and Outlook 2020 to 2027 - Food & Beverage Herald

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