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When embarking on a weight loss journey theres always unexpected obstacles that come up that can set a slimmer back. However, at Christmas time slimmers tend to ditch their diets for good, in order to indulge in some festive treats, wasting a lot of the progress that has already been achieved. So, whats the best way to stick to a diet?Nutrition and weight loss expert, Jane Michell, founder of Jane Plan shared with Express.co.uk some top tips and tricks for sticking to a diet.

1. Place goals

Jane states that the most important aspect of sticking to a diet is to set realistic goals, she explained: The most important aspect of sticking to a diet is to set your yourself realistic goals.

Why? Because if you set yourself unrealistic goals and then dont achieve them, you will give up and feel like you have failed.

Instead she encourages slimmers to set realistic goals of losing one to two pounds a week.

READ MORE:Man loses175lbsusing 'life-changingdiet plan

2. Find a key motivator

As a slimmer finding a key motivator for weight loss could be the kind of push needed for someone to stick to their diet.

Jane said: It could be because you want to wear a certain outfit, or combat a health issue like elevated blood pressure.

It could be that you want to lose weight for a wedding, a party, a holiday or because you cant tie up your shoe laces anymore without help.

Whatever your motivation, make sure it is specific and then write it down and keep it somewhere close to you, so when you lack motivation, you can look at it and re motivate yourself, she encouraged.

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3. Write it down

Jane revealed: There is a great deal of evidence to suggest that people who write down what they are eating (a weight loss diary) are more successful in losing weight AND keeping it off in the long term.

So, keep track of whats being eaten in order to stick to the diet as well as track the achieved weight loss.

4. Do a weekly weigh in

According to Jane, a slimmer should engage in weekly weigh ins in order to stay motivated and on track.

Do a weekly weigh in - no more and no less, she said.

If you weigh in more frequently you may have the odd result that suggests you have gained weight, explained Jane.

This is because our body weight varies throughout the day, and a supposed weight gain may discourage you from sticking to your diet.If you weigh in consistently once a week, you will be able to track your progress.

And even better, if you do this in conjunction with your weight loss diary youll be able to rationalise and understand why some weeks you have lost a lot of weight, whilst other weeks you may not have done. This prevents us from those classic I dont know why I havent lost weight this week moments.

These can be very de motivating but regularly weighing in and tracking progress you will remain more motivated and are more likely to stick to your diet, she said.

5. Eating with eyes

According to Jane, people eat with their eyes therefore are more likely to overeat and gain weight, as if a slimmer has a cupboard full of unhealthy or high calorie foods, they are more likely to eat them.

Jane explained: We eat with our eyes so if you have unhealthy or high calorie foods visible, you are more likely to eat them.

Instead, Jane suggests that a slimmer should hide away or conceal the unhealthy treats in order to defer temptation, she said: Hide away tempting treats in cupboards and even better, in opaque boxes.

When shopping, avoid the aisles in the supermarket where the unhealthy foods are displayed that way you are less likely to buy them, and avoid going anywhere where you may be tempted.

For example, if your morning routine is a take out coffee and a croissant, change your routine, dont go into the coffee shop just for coffee if you do, you are quite likely to find the croissant too hard to resist.

Instead, start having a coffee or herbal tea (even better) at your desk and made in the office or at home, she suggested.

6. Carry healthy snacks

Healthy snacking to keep the hunger at bay is one of the top tips to achieve a healthy weight loss. Jane recommends carrying healthy snacks around to quench any ebbing of hunger.

She said: Always make sure you have a snack, like an apple, in your bag when you are on the go. That means you wont get caught out if you feel hungry and find your only option is an unhealthy snack.

7. Plan ahead

Dieting isnt all doom and gloom, a healthy weight loss is achieved through a well balanced diet and this doesnt mean that a slimmer has to sacrifice all treats in order to lose weight. Moderation is key.

If youre eating out plan ahead, said Jane. This will help you make healthy choices in the restaurant. Avoid starters and dessert and instead stick to a main course.

Or have 2 starters! Dont be afraid to ask the waiter for more plainly cooked food, eg grilled fish and no sauce.

Avoid alcohol as they say will power is soluble in alcohol. Alcohol is not only high in calories, it also makes you more relaxed so youre more likely to come off your diet if youve had a drink, she revealed.

8. Avoid an all or nothing approach

Occasionally everyone slips up, but thats natural. Dont throw away all of the weight loss progress over one slip-up.

Everyone slips up occasionally its only natural, If you do this, dont beat yourself up, instead get back on your diet and put your slip up down to experience, said Jane.

One common scenario is that someone offers you a biscuit with your coffee mid-morning, you accept and then have another.

After this you say to yourself, oh well I have ruined my diet today, I may as well give up completely today. A better approach is Oh well, I had 2 biscuits, never mind, Ill have a bowl of soup for lunch with no bread and I wont add any rice to my dinner tonight that way Ill be back on track.

Dont use the slip up as an excuse to give up on your entire diet!, Jane, founder of Jane Plan, urged slimmers.

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Weight loss: Best tips to stick to a diet revealed by top weight loss expert - Express

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The motivation to lose weight and build a ripped body can come from anyone and anywhere movies - its sun-kissed actors, bodybuilders, athletes and even your peers or family members. 26-year-old Mradul Singh Rajpoot, who at his heaviest weighed 92 kgs with a fat accumulation of 38 per cent, cites his younger brother Hitendra Singh Rajput as his biggest fitness inspiration and motivator. He helped Mradul trim from 92 kgs to 66-67 kgs with only 16-17 per cent fat accumulation.

Says Mradul,growing up, my brother used to be very skinny. He was sent to a boarding school to complete his education. And, when he returned home, post his high school graduation, he had completely transformed his physique from slim and lanky to super fit. He had also developed a great personality. Everyone was a fan of his new personality, including me he says.

During this same period, my body weight kept tipping towards the heavier end of the weighing scale, he adds.

The thing is, Id always been a foodie and to top that, in 2016, I'd started working the graveyard shift for a private company. So, Id only be back home by 7 am. Consequently, my eating habits went from bad to worse, he says. Id stay up all night, and when Id finally come home, Id gorge on poha, samosas, sandwiches, namkeen and chips."

"At that time, I used to sleep early in the morning, after eating 2-3 samosas, 1-2 plates of poha, sandwiches and 1-2 packets of chips in one go. Then, Id wake up around noon, and eat a heavy lunch, followed by evening snacks and a very heavy dinner. It was almost like my whole life was dependent on junk, fast and processed food. A culmination of these bad eating habits and a hectic lifestyle led my body to gain a lot of weight. 92 kgs to be precise.

But before things could take a turn from bad to worse, Mradul decided to lose weight with his brother by his side as his motivator and guiding force. Since he knew a lot about healthy living, considering he'd transformed himself so nicely, he started giving me fitness tips. Slowly, I also started collecting information on the various reasons that lead to weight gain, weight loss as well as sustainable weight loss approaches. Through the information I collated, I was able to devise the below weight loss plan,

The first thing Mradul did was control his calorie intake by not dieting but by substituting the junk food from his meals with macros (macronutrients - fat, protein, and carbohydrates) from solid food. Think oats, nuts, green veggies and meat. This is what he ate on a daily basis:

First Meal: Breakfast (9-10 am) - 1 banana + eggs (2 whole eggs + 1 egg white) + 60-70 grams oatmeal

Second Meal: Snacks (11-12 am) - 150 grams mixed fruits + dry fruits (almonds, raisins: 5-10 pieces)

Third Meal: Lunch (2-3 pm) - 120 grams brown rice + 3 cups of green vegetables

Fourth Meal: Snacks (5-6 pm) (Pre Workout) - 1 teaspoon peanut butter + 1 slice brown bread

Post-workout - 1 scoop of Whey protein

Fifth Meal: Dinner (8-9 pm) - 100 grams of sweet potato/chicken + 1 teaspoon of olive oil (in any form) + 3-4 cups of green vegetables

I lost my 6 kgs in about 45 days itself. I went from 92 kgs to 86 kgs. And, as I kept learning more about nutrition and healthy eating, through research, I kept changing or rather updating my diet every 45 days, which aided further weight loss he explains. Mraduls healthy eating weight loss plan was also supplemented with the help of the below exercise regime.

"I used to hit the gym for an hour and a half daily for a strength/weight training session followed by a 30-minute of cardio routine. Every day, Id indulge in 5-6 exercises dedicated for each body part with 15,12,12 reps. This is what my workout plan looked like":

Monday: Chest Workout

Tuesday: Shoulder Workout

Wednesday: Back Workout

Thursday: Arms Workout

Friday: Chest and Shoulder Workout

Saturday: Legs Workout

Sunday: Rest Day (No Workout)

ALSO READ: How to workout 12 times a week and still lead a semi-normal life

By following the above routine, my metabolism has become very fast now. So, now, I indulge in heavy and high-intensity workouts to maintain my weight as well as eat protein-rich food. I also drink a lot of water and try to get 7-8 hours of sleep.

ALSO READ: Here's how drinking water at regular intervals can help you lose weight and increase your metabolism

Maintain courage, passion and stubbornness. These three attributes will lead you to your final goal.

Disclaimer: The diet and workout routines shared by the respondents may or may not be approved by diet and fitness experts. GQ India doesn't encourage or endorse the weight loss tips & tricks shared by the person in the article. Please consult an authorised medical professional before following any specific diet or workout routine mentioned above.

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Honey Boo Boo, aka Alana Thompson, started getting a Fab Fit Fun subscription box this year. Shes making an effort to live a healthier lifestyle, which includes losing weight. With her custodian and sister Pumpkin, shes working at her image and through the harsh reality of estrangement from her mom, Mama June Shannon. Just 14, unbelievably, during the season of love, someone found it in themselves to body-shame the teen.

Fans of Alana Thomspon know that her mom and others in the family struggle with their weight. But, for her, its not too late to try and stop the trend as shes young. And, shes really making an effort these days. Despite body-shamers, the young and cheerful personality keeps on smiling through life. TV Shows Ace reported in October, that Honey Boo Boo started doing Boom Bod promos. And, shes losing some weight. But even then, someone thought it okay to body-shame a teen.

Body shamings bad for the mental health of those who are victims of it. But, Time Now News reported that its also bad for the mental health of those who do the body-shaming. Referring to a 2016 study, it emerged that people who body-shame others, often suffer from low esteem. And, often, they body-shame others because of their own shortcomings. It really doesnt make them feel any better despite their attempts at redirection. Maybe thats why Honey Boo Boo seldom responds to those critics.

On Tuesday, Honey Boo Boo took to her Instagram and shared a photo of her sitting astride a giant ball at Dave & Busters. Always amusing, Alana looked like she sat on a giant egg. In the picture, she looks obviously slimmer around the waist, pretty, and very happy being out with friends. But someone decided to slap at her. Alana captioned her pic with, uptown girls .

Many fans responded and complimented her on her happy post. One said, Alana you must be loosing weight thats awesome your waste looks so small keep up the good work girl (sic). But one critic decided to body-shame Honey Boo Boo, saying, Your almost as round as that ball (sic). Another responded with, lmao. Another person commented on wide-angle.That really annoyed fans of the young teen. After all, its not a nice thing to say at all. They slammed the trollers for their comments.

Quick to defend Honey Boo Boo, fans told off those who said cruel things to her. Heres what some of them said:

What do you think about people who chose to body-shame a young teenage girl whos making an effort to lose weight and get healthy? Do you think thats shameful? After all, the festive seasons meant to be a time of love and kindness. Sound of your thoughts in the comments below.

Remember to check back with TV Shows Ace often for more news about Honey Boo Boo.

Woryn is a writer who started a small book publishing company in New Zealand. He wrote three books, one of them published by Domhan. Woryn prefers to write about real things, rather than fiction which is why he likes to focus on Reality TV shows.

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Honey Boo Boo Gets Body-Shamed Despite Losing Weight And Looking Good - TV Shows Ace

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Bite-sized goals are easier to achieve and increase the appetite for continuous improvement.

Achieving personal goals can be as frustrating as trying to nail Jello to a wall.

Lose weight? Get more sleep? Exercise daily? Take a dream vacation? Improve a relationship? Earn a promotion? Read more books? Watch less TV? Cut back on social media? Save more money? Spend less?

The list can go on. Set a worthy goal, then fail to achieve it. Honestly, most of us have been there, done that.

Rather than buy a ticket for another guilt trip, how about taking a different approach?

That different approach can be found in the work of wellness expert Brett Blumenthal. Rather than set yourself up for disappointment by setting big goals, she suggests one small change per week for 52 weeks. You might call it the yard by yard its hard, but inch by inch its a cinch approach to personal improvement. Its a surprisingly simple formula: focus on one small, achievable change every week. Then enjoy the accumulation effect.

Regardless of whats on your wish list of personal improvement, this research-based practice works.

Blumenthal provides user-friendly guidance in 52 Small Changes for the Mindand other books that bring sanityand hopeto anyone whos serious about doing better and being better.and other books that bring sanityand hopeto anyone whos serious about doing better and being better.

Rodger Dean Duncan:Your 52 small changes approach to personal improvement has proved to be very popular. Whats the rationale behind this practice?

Brett Blumenthal

Brett Blumenthal:Small changes have proven to be more successful than major overhauls for the following reasons

1.One Big Goal = Many Small Steps.Every big goal, such as weight loss, requires many smaller actions, such as cutting out bad foods, exercising, and eating healthy foods. Breaking a big goal into smaller components makes the process more manageable.

2.Extremes Dont Work:Overhauling our life, or more simply put going from all to nothing, or vice a verse causes burn out. Taking a step-by-step approach, however, makes change seem less overwhelming.

3.It Feeds Our Need to Succeed:Small Changes feed our need to succeed. With each one you successfully make, you fill up your confidence bucket, enabling you to take on more. Allowing ourselves to master small adjustments, gives us an opportunity to feel successful, and the motivation to forge ahead towards the bigger goal.

Duncan:If a person chooses to try the 52 small changes approach, whats a good way to decide exactly which changes to pursue?

Blumenthal:The 52 Small Changes concept is to make one small change per week over the course of one year to eventually add up to a larger change. Although the concept is structured, the changes you want to make are really up to you and the personal journey you want to have. In short, the changes should be small, manageable and quantifiable.

For instance, drink eight glasses of water per day vs. hydrate more. A change like get fit does not qualify as a small change. Instead, break it down into smaller ones such as: Do cardio three times per week for 30 minutes each time. Then, maybe the next week, Do ten minutes of weights three times per week. Take a week to integrate a change before moving onto a new one. But if one change is really easy or already part of your life, feel free to move forward with another change.

Duncan:You recommend writing a personal mission statement. What are the steps to doing that, and what role can a carefully-crafted mission statement play in a persons quest for improvement?

Blumenthal:In business, companies summarize who they are and their intentions with a mission statement. This gives the company direction and a consistent message in everything they do. Developing a personal mission statement gives you a way to definethe type of person you want to be and how you want to contribute to life.It should be reflective of your authentic self, and not other peoples beliefs or values. It should inspire you, and if written well, should provide you with direction and motivation in life.

Try keeping your statement to a few sentences or a short paragraph. Key questions to answer should includeWhat characteristics and qualities do I want to live by?How do I want to contribute to the world?What kind of influence do I want to have? andIf I could, what legacy would I leave?

Heres an exampleI will put my best into everything that I do. I will live with passion and choose activities, friendships and relationships that bring out the best in me. I will bring out the best in others and will give my time and energy to the things I value.

Goal setting? Yard by yard it's hard, inch by inch it's a cinch.

Duncan:You recommend a six-step path to personal reinvention. In a nutshell, what are those steps?

Blumenthal:Just like any large corporate transformation requires a structured plan to be successful, so do we as individuals.

The six steps I recommend are

1.Identify the Need.Realize something in your life isnt right and that a change is needed (e.g., you have been miserable at your job for more than a year)

2.Discover Yourself.Build self-awareness so when you embark on a transformation you remain true to yourself and set yourself up for the greatest possible success

3.Design Your Vision.What change do you really want to make and what is the end result you want?

4.Create the Plan.Think about timeline, smaller milestones and all that is required to make the change happen.

5.Make it Happen.Put the plan into action and hold yourself accountable

6.Monitor Progress.Check in and see if things need to be adjusted or if timelines need to change based on your progress.

Next: In Goal-Setting, Small Can Translate To Big Success

Visit link:
Try This Bite-Sized Approach To Personal Improvement - Forbes

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Contrary to the popular belief, you cant actually lose weight by just working out in a gym 24x7 or worse, crash dieting. Youll just end up harming your health and mental well-being if you go down this road. To lose weight in a sustainable manner a manner thatll prove successful in the long-run you need to adopt fitness as a part and parcel of your life. If youre confused as to how to commence on this route, let 28-year-old Amith Rvs inspiring journey guide you.

Amith tells us that at his heaviest he weighed in-between 136-140 kgs. I was afraid to weigh myself, but I know I weighed in-between this range, 5 years ago. And, it is not like I didnt have the urge to lose this weight before, the scale tipped so high. I did. I always wanted to be fit. But nothing materialised until performing even day-to-day activities became difficult. I suddenly realised that theres no escaping this now, and consequently, commenced on the below weight loss routine to trim from 136-140 kgs to 99 kgs."

Amith lays down a simple 3-step plan that helped him get started on his weight loss journey. The trick was to keep it simple. So, I commenced by making these small changes in my life:

1.Walking - I started walking 10k steps daily. This is a wonderful way to start living a more active lifestyle.

2.Moderation is key - Eat everything but in moderation. Adherence and sustainability are the two keys to any weight loss journey. Pro tip: Include fibre-rich foods in you diet. They curb overeating by keeping you fuller.

3.Mix and match - Apart from walking, I also started indulging in both strength training and cardio routines. The two combined will get you optimum results. Here, take a look the exercise regime that helped me whip myself in shape below".

QUICK READ: The best cardio machine for every type of workout

Says Amith, Id workout for 5 days/week, and also kept changing my routine every 3 months before my body got adapted to the below Upper Body Split and Lower body Split and Cardio routines.

Upper Body -

Flat Dumbbell Chest Press: 15 reps - 2sets

Incline Dumbbell Chest Press: 15 Reps - 2 sets

Shoulder Press: 15 reps - 2sets

Lateral rise: 15reps - 2 sets

Bicep and Triceps -

Barbell curls: 15reps - 2 sets

Tricep Skull crushers: 15reps - 2 sets

Lat Pulldown: 15reps - 2 sets

Dumbbell Rows: 15reps - 2 sets

Followed by 20 mins of LISS (low-intensity steady state) cardio - cycling, elliptical or treadmill

Free Squats: 100 reps 20*5

Leg Press: 15reps - 2 sets

Leg extension: 15reps - 2 sets

Hamstring Curls: 15reps - 2 sets

Calf Raise: 15reps - 2 sets

Followed by walking on the treadmill for 30 minutes

In accordance with his 3-step approach to weight loss, Amith reveals that he followed a flexible dieting, also known as If It Fits Your Macros or IFFYM, plan. My diet comprised single source foods (foods that boast only one of these three macros: protein, carbs or fats) such as milk, sprouts, eggs, vegetables, rice and dark chocolate. If were to outline my daily meal plan, this is what it would look like -

Early Morning: A glass of amla juice

Breakfast: 1 glass milk with millets + 1 apple + a handful of almonds

Lunch: 1 cup rice with veggies (carrots, beans, okra, beetroot) with 2 eggs

Dinner: A salad made from sprouts, apples, beetroot and carrots and a glass of juice, occasionally

QUICK READ: How to lose weight by calculating your macronutrients right

"After losing a massive amount of weight, your body weight will keep fluctuating. It becomes range bound rather than just limiting to a fixed number. I do have bad days on the weighing scale, but I don't let these days turn into weeks or months. However, if there is one key to weight maintenance, I'd say, it is working out regularly. I ensure that I dont miss a workout session for more than three days in a row, and like I already said moderation is important, I eat everything but count my calories to keep my weight in check."

- "Understand the basics of calorie tracking, macros and flexible dieting

- Don't eliminate junk foods, just see to it that you don't over-indulge in them

- Don't work against your body, work with your body to get rid of the excess fat

- Be patient. It is going to take longer than you expected. But in the end it is going to be worth it.

- Most importantly, enjoy the process. I discovered a new person in me. I am now able to help others who have are struggling to lose weight via Instagram, YouTube and Quora."

Disclaimer: The diet and workout routines shared by the respondents may or may not be approved by diet and fitness experts. GQ India doesn't encourage or endorse the weight loss tips & tricks shared by the person in the article. Please consult an authorised medical professional before following any specific diet or workout routine mentioned above.

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Photo Credit: Pixabay / Steve PB

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For the lucky ones, weight gain is limited to a few extra pounds put on over the holidays and lost in the weeks thereafter. But for those with a predisposition for overweight, the battle of the bulge is a lifelong struggle punctuated by physical and emotional challenges.

Given the range of serious medical issues associated with overweight, from diabetes, hypertension, cardiovascular disease and cancer to infertility, sleep apnea and skeletal pain it comes as no surprise that the medical community considers obesity as a disease unto itself.

Shocking statistics indicate that 90% to 95% of people with obesity who diet and lose weight will gain it back within the first year, often with interest. The urgent need for an innovative approach to treat and cure this disease has led to the establishment of the Israeli Center for Obesity Management, a division of the Department of Endocrinology at Sheba Medical Center. In the words of Dr. Gabriella Lieberman, Senior Specialist at Shebas Endocrine Institute and director of the Center: Theres no one obesity, but obesities. People who suffer from overweight have different problems. Thats why the one-size-fits-all approach often fails.

When seeking the main culprit responsible for the obesity epidemic, a phenomenon identified only in the last 50 years, its impossible to ignore the advent of processed foods and the accompanying plastic packaging and preservatives. Were exposed to hundreds of chemical additives, categorized by the FDA as GRAS (generally recognized as safe) but whose long-term effects have not been thoroughly examined, explains Professor Amir Tirosh, director of the Division of Endocrinology, Diabetes and Metabolism at Sheba Medical Center. We can assume that most are indeed safe, but we dont need more than a couple dozen that are not so safe to suffer the consequences.

In a ground-breaking study conducted together with colleagues from Harvard University, Prof. Tirosh observed the effects of propionate, a common preservative found in bread and baked goods. The findings indicated that the chemical can cause elevated glucose levels, impacting insulin sensitivity and metabolism. While the findings are not yet thoroughly validated in humans to warrant a recommendation to ban propionate, they do point to the need to more closely assess the potential long-term effects of this chemical, and perhaps others.

Personalized Medicine

At the Obesity Center in Sheba, patients undergo a thorough assessment by a team of experts, including an endocrinologist, dietitian, psychologist, and sports medicine expert. After measuring the patients metabolic rate as well as body composition, the experts will consult and evaluate all this information to build a tailor-made plan that will suit the individuals distinctive needs and parameters.

After receiving their individualized plan, patients come periodically to the clinic to meet with the professionals and track their weight loss. Depending on the circumstances, patients might be candidates for GI procedures such as intra-gastric balloons and duodenal devices, endoscopic gastroplasty or bariatric surgery. Additionally, there are relatively new weight loss drugs available today that have taken the medical community by storm.

Saxenda and Belviq work by suppressing appetite and have relatively few side effects, which usually disappear with time. Naturally, the first question that people ask is, How much weight will I lose with this drug? Dr. Lieberman is quick to explain that there is no way she can predict weight loss. There is an average weight loss, but each individual will experience different results. Some people may lose more than the average; for others, the drug may be less effective. Although shes seen patients make tremendous progress with the help of meds, Dr. Lieberman makes it clear that the drug can never replace lifestyle modification.

The good news is that it doesnt take much to achieve a drastic improvement in health. According to Prof. Tirosh, in order to treat metabolic disorder, prevent diabetes, and improve high blood pressure, the goal is to lose 7% of body weight. If a patient can maintain that long term, Im very pleased.

In the Pipeline

According to Prof. Tirosh, one of the most exciting breakthroughs in obesity research is in the field of genetic screening. Were performing clinical studies here at Sheba, and can now screen for mutations to determine if patients have a genetic propensity to obesity. Its extremely validating for patients who have been struggling all their lives with obesity to know that theyre not to blame; its not because theyre lazy, or because they lack willpower.

In a departure from conventional methods, Dr. Ruth Percik, senior specialist at the Endocrinology Institute at Sheba Medical Center, is researching weight loss solutions to obesity employing neurofeedback training the brain and harnessing its power to gain greater self-awareness and increase self-control, willpower, and mindfulness. The notion that obesity could be treated via the brain occurred to her during her stint at the Max Plank Institute for Brain Research in Leipzig, where she learned that the behavior patterns linked to obesity were clearly evident in brain scans.

Scientists at Max Plank observed that the people who had lost their excess weight and kept it off for a decade, so-called Sustained Weight Losers, all had something in common: a high level of self-discipline, which is clearly discernible in brain imaging, Dr. Percik explains. To illustrate, when obese people were shown an image of their favorite food, all the pleasure centers in their brain lit up, light those of an addict. By contrast, when SWLs were shown their favorite food, only part of their brains were stimulated; the rest was quiet. This indicates an internal restraint mechanism, which translates as their ability to adhere to their menu plan.

A year and a half after the study, 70 percent of participants have managed to keep the weight off, corroborating Dr. Perciks hypothesis.In clinical studies at Max Plank, neurofeedback is measured via fMRI, which is not economically feasible for widespread use. Dr. Percik and her team are currently exploring a device that is compact, portable and user-friendly, to be incorporated at hebas Obesity Center.

Nutritional Blues

After all is said and done, it comes down to food intake. Dana Weiner, director of the Department of Nutrition at Sheba Medical Center, debunks the myths of traditional dieting.

When people come to me, they expect me to hand them a diet. But I dont believe in one diet that suits everyone. Even the Mediterranean diet, which I agree is an excellent food plan, is not suited to everyone.

Dana believes that like all areas in medicine, nutritional science is moving in the direction of a more personalized diet, based on a persons genetic makeup and where they live. She brings evidence from study of the Blue Zones, five areas in the world whose inhabitants exhibited greatest longevity and quality of life, yet each have distinctively different diets. What they all do have in common in terms of regimen is a plant-based diet, strategies to prevent overeating, limited alcohol consumption, and physical activity as a way of life.My dream as a dietician at Sheba is to establish nationwide programs to educate families about healthy lifestyle and proper eating habits along with food security for everyone, Dana shares.

Would you like more articles like this from Sheba Medical Center?

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Weighing In on the Obesity Epidemic - The Jewish Press - JewishPress.com

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Men are nearly two times more likely to develop blood clots while undergoing testosterone therapy, according to University of Minnesota research.

The study, which was published last month, found that men on testosterone therapy were at a heightened risk of developing a condition commonly known as VTE. With this condition, blood clots form in the veins and travel to the lungs, potentially blocking the blood supply. Men seek testosterone therapy for a variety of reasons, including low testosterone levels and sexual dysfunction.

These findings were shown in both men with and without hypogonadism, a condition where the body does not produce enough testosterone naturally.

There hasnt really been [this] kind of care given to a hypogonadism diagnosis. A lot of other studies either control for it or restrict it to one specific group of men, said Robert Walker, the study's lead and a research assistant at the Universitys Minnesota Population Center.

In the study, researchers separated men with the condition and men without it. By doing so, they were able to see a near doubling of risk in both groups, he said. They were also able to control for factors such as smoking status, obesity and race.

Overall for Americans, there [are] about 1 million cases of VTE annually, Walker said, which includes a lifetime risk of one in 12 people. Symptoms include leg pain, swelling and rashes.

While men typically receive testosterone therapy for hypogonadism, they may also seek it for unwanted weight gain or emotional regulation.

"These findings are important, particularly for the men with no hypogonadism, as they suggest that off-label testosterone use for symptoms of 'male menopause' may be causing harm, said Pamela Lutsey, a co-author of the study and University associate professor in the Division of Epidemiology and Community Health, in an email to the Minnesota Daily.

When men seek testosterone therapy for reasons other than hypogonadism, there is not necessarily an official diagnosis. However, treatment could fix those symptoms, Walker said.

Testosterone therapy is more than just a kind of stroke and heart failure risk factor, we have to take into account other cardiovascular symptoms, he said.

In the future, the researchers can use the same study design to test the effects of testosterone therapy on women, Walker said.

Women who need to take testosterone for one reason or another may also be put at a risk, he said.

Women are often at risk of developing VTE while pregnant because of the pressure on their organs or afterward in the postpartum period, Walker said.

An important next step is for other researchers to reproduce these results, said Richard MacLehose, another co-author of the study and University associate professor in the Division of Epidemiology and Community Health.

Walker said he began this study because of the lack of research papers on the effects of testosterone therapy.

The story of the paper is really just to think before you prescribe, he said.

Continued here:
Men who receive testosterone therapy nearly twice as likely to develop blood clots, researchers find - Minnesota Daily

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NORTHBROOK, Ill., Dec. 11, 2019 (GLOBE NEWSWIRE) -- Clarus Therapeutics, Inc. today announced the appointment of five senior leaders, each of whom bring valuable industry and category experience to the team. Together they strengthen the companys commercialization capability for JATENZO (testosterone undecanoate) capsules, the first-in-class oral testosterone replacement therapy approved by the U.S. Food and Drug Administration (FDA) for the treatment of hypogonadism. See indication and important risk information, including boxed warning below.

Dr. Newmark, Mr. Jaeger, Mr. Rodriguez, Ms. Wright and Mr. Holloway join a management team led by Robert Dudley, Ph.D., Clarus Therapeutics Chief Executive Officer and co-inventor of JATENZO. Dr. Dudleys legacy in mens health includes CEO leadership of the company that developed and launched AndroGel, a product he co-invented and the last major advancement in testosterone replacement therapy delivery.

We are proud to bring Jay, Frank, Jose, LaTonya, and James into an organization that shares their focus on innovation and excellence. They have each demonstrated an ability to connect with medical professionals who are invested in mens health, said Dudley. Their expertise will help us make the long sought-after oral testosterone option widely available to appropriate hypogonadal men.

INDICATION

JATENZO (testosterone undecanoate) capsules, CIII, is an androgen indicated for testosterone replacement therapy in adult males for conditions associated with a deficiency or absence of endogenous testosterone:

Limitation of use

Safety and efficacy of JATENZO in males less than 18 years old have not been established.

IMPORTANT SAFETY INFORMATION

WARNING: INCREASES IN BLOOD PRESSURE

CONTRAINDICATIONS

JATENZO is contraindicated in men with carcinoma of the breast or known or suspected carcinoma of the prostate, in women who are pregnant, in men with a known hypersensitivity to JATENZO or its ingredients, or in men with hypogonadal conditions that are not associated with structural or genetic etiologies as JATENZO has not been established for these conditions and there is a risk of increased blood pressure with JATENZO that can increase the risk of MACE.

WARNINGS AND PRECAUTIONS

ADVERSE EVENTS

The most common adverse events of JATENZO (incidence 2%) are headache (5%), increased hematocrit (5%), hypertension (4%), decreased HDL (3%), and nausea (2%).

DRUG INTERACTIONS

USE IN SPECIFIC POPULATIONS

The safety and efficacy of JATENZO in pediatric patients less than 18 years old have not been established. Improper use may result in acceleration of bone age and premature closure of epiphyses.

There have not been sufficient numbers of geriatric patients involved in controlled clinical studies utilizing JATENZO to determine whether efficacy or safety in those over 65 years of age differs from younger subjects. There is insufficient long-term safety data in geriatric patients utilizing JATENZO to assess the potentially increased risk of cardiovascular disease and prostate cancer.

Please see accompanying full Prescribing Information, including BOXED WARNING on increases in blood pressure.About JATENZO JATENZO is a first-in-class proprietary oral soft gel formulation of testosterone undecanoate for testosterone replacement therapy in adult males for conditions associated with a deficiency or absence of endogenous testosterone.

JATENZOs proprietary formulation is built around testosterone undecanoate a testosterone prodrug that the body converts to testosterone. In the JATENZO pivotal inTUne (investigation of its oralTestosteroneUndecanoate) clinical trial, 87% (n=222) of men treated with JATENZO achieved average circulating levels of testosterone in the normal range for men.

About Clarus Therapeutics, Inc.Clarus is a men's specialty pharmaceutical company developing and preparing for the commercial launch of JATENZO, a product protected by patents issued in the United States and in other major pharmaceutical markets around the world. Clarus owns the worldwide, royalty-free commercialization rights for JATENZO.For more information, please visit:www.clarustherapeutics.com.

Media ContactAmir KhanPhone: (212) 462-8767Email: Amir.Khan@Syneoshealth.com

2019 Clarus Therapeutics, Inc. All rights reserved.

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Clarus Therapeutics Expands Executive Team in Preparation for Landmark Launch of JATENZO (testosterone undecanoate) Capsules CIII - GlobeNewswire

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A 36-year-old cis man born without testicles in Belgrade, Serbia has just received a testicular transplant from his identical twin brother to help his body produce its own testosterone and sperm.

Its only the third such surgery ever to occur in the world, and doctors say it could eventually be applied to trans men using the removed testicles of trans women, but ethical and legal concerns could complicate the matter.

Related:Ibuprofen has a negative impact on men testicles according to new study

The surgery was a success, though it wasnt easy. It involved sewing together two arteries and two veins that were less than 2 millimeters wide within two to four hours before the organ became non-viable, according to The New York Times. Both brothers are doing well, they both now have one testicle each and the recipients testosterone levels are already at normal levels.

Because the men both have the same genetic makeup, theres no need for the immune-suppressing drugs that most transplant recipients require to avoid having their bodies reject foreign tissue.

The brothers contacted lead surgeon Dr. Miroslav Djordjevic about the procedure after theyd heard hed performed a successful uterus transplant between twins sisters, enabling the recipient to give birth. In the testicular procedure, Dr. Djordjevic didnt reconnect the testicles vas deferens, which wouldve enabled the recipient to release sperm from the donated testicle. Such a reconnection is possible.

Though its rare for a cisgender man to be born without testicles, Dr. Djordjevic says the testicular transplant could also be applied to accident victims, wounded soldiers, cancer patients and trans men using testicles donated by transgender women and others.

However, a legal issue might arise as anyone who fathered children using sperm released or harvested from a donated testicle as the child would, in essence, have the donors DNA and not the recipients the donor or their surviving loved ones would likely have to give permission to have children in such a case, raising a potentially sticky legal issue.

Several transgender men have contacted Dr. Djordjevic to ask if the surgery could help them develop testosterone without the need for constant hormone injections. While Djordjevic says the potential rejection of donor tissue remains the largest consideration for whether or not to attempt any organ transplants, he also says he has developed a surgical plan for transplanting a penis onto a body that is anatomically female, and that he hoped to begin performing that surgery within the next year or so, according to The New York Times.

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Surgeons successfully performed a testicle transplant. The procedure could help trans men one day. - LGBTQ Nation

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A 36-year-old Siberian man born without testicles can now father children, thanks to his identical twin brother who donated one of his testicles, according to an international team of surgeons.

The man is now the third person known to have undergone a testicular transplantation surgery, which lasted six hours.

"He's good, he looks good, his brother looks good," Dr. Dicken Ko, a transplant surgeon and urology professor at Tufts University School of Medicine in Boston, who flew to Belgrade to help with the procedure told The New York Times.

The donor, who already has children, should remain as fertile as he was before, despite giving up a testicle, according to the surgeon.

The Siberian man was born without testicles a rare condition. As a result, he could not produce sperm and the male hormone testosterone.

Testicular transplantation offers a ray of hope to other people as well, including transgender people, accident victims, wounded soldiers, and cancer patients.

This form of transplantation is not the most opted procedure. Generally, people who lose their testicles opt to take testosterone to replace the hormones and receive testicular prostheses to restore the appearance.

The Siberian sibling chose surgery over hormone replacements. The surgery was intended to give the recipient more stable levels of the male hormone testosterone than injections could provide, to make his genitals more natural and more comfortable and enable him to father children, says Dr. Ko.

The doctors do not expect any complications arising from the surgery. The success of transplantation among twins is high, as they share similar genetic makeup, meaning they have almost identical tissues in their bodies, say medical experts.

However, the procedure did not come without its share of challenges. The surgeons had to be swift and precise. "Once you remove the testicle from the donor, the clock starts ticking very fast," Dr. Branko Bojovic, an expert in microsurgery at Harvard Medical School and part of the team in Belgrade told the New York Times.

"If they do not act fast, the testicle will lose its viability a testicle is viable for only four to six hours," he adds.

After the surgery, the Siberian man's testosterone levels reached the normal range and his testicles will now carry sperm, say doctors. He can father children but he won't be able to reproduce sexually, for now.

This is because doctors could not connect a structure called the vas deferens, which carries the sperm out of the testicles. However, the team says, another operation can fix this in the future.

In the meantime, however, he could undergo in vitro fertilization, where his sperm can be harvested and used to fertilize embryos, say doctors.

In the future, transplantation could find use among people wanting to undergo female-to-male sex reassignment, says the team. Doctors throw away the penis and testicles, after male-to-female reassignment surgery.

Instead, the team argues that these discarded organs could be used for transplants. "We have to do this as soon as possible, to stop putting healthy organs in the garbage," says Dr. Miroslav Djordjevic, the lead surgeon.

Link:
Man born without testicle gets one from identical twin brother so he can have children of his own - MEAWW

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