Search Weight Loss Topics:

Page 1,804«..1020..1,8031,8041,8051,806..1,8101,820..»

Home » Page 1804

By Mary Hightower/U of A System Division of Agriculture

Does your fitness program need a little boost now that the summer is winding down?

The fall edition of Walk Across Arkansas begins Sept. 17 and runs through Nov. 18.

Over the last decade, thousands of Arkansans have made Walk Across Arkansas their opportunity to start or continue a fitness program, said Lisa Washburn, associate professor-health, for the University of Arkansas System Division of Agriculture. While were not really walking across the state, we do have thousands of people across Arkansas who form teams and commit to eight weeks of exercise, she said. Many of our participants have credited Walk Across Arkansas with making fitness a permanent part of their daily routine.

Registration for Walk Across Arkansas will open Sept. 5. Information and registration can be found at http://bit.ly/WAA-Fall-2017.

For more information about Walk Across Arkansas or other extension fitness programs, contact your county extension agent or visit http://www.uaex.edu.

Original post:
Exercise program negins Sept. 17 - Lifestyle - Paris Express - Paris ... - Paris Express

Read More..

GETTY

When you are trying to lose weight, there are many different tips and tricks people offer to make the process easier.

However, a new study has revealed a tip that requires no effort at all: Stepping on the scale every day.

Researchers from Drexel University and the University of Pennsylvania studied 294 women of various sizes and asked them how often they tracked their weight.

Positive weight gain snaps spread across social media with the hash tags #screwthescale and #gainingweightiscool. After using the MyProtein diet and healthy exercise.

1 / 13

Positive weight gain snaps spread across social media

The womens body fat percentages were taken after six months and again after two years.

The researchers used this to determine the womens BMIs and found that women who stepped on the scale more frequently had a dip in their BMI compared to those who didnt.

Study co-author Diane Rosenbaum, Ph.D and psychologist at the University of Pennsylvania said: The losses in BMI and body fat percentage were modest, but still significant, especially keeping in mind that these women were not part of a weight loss program.

We did not expect that, in the absence of a weight loss intervention, folks would be losing weight.

High-protein, low-carbohydrate diets are all the rage right now and for good reason. Protein is an important component of every cell in the body. Hair and nails are mostly made of protein and your body uses protein to build and repair tissues.

1 / 11

Women with higher BMIs and body fat percentages surprisingly weighed themselves more at the beginning of the study compared to women with lower BMIs.

The scientists said that constantly being reminded of your weight could help to keep diet and fitness goals in check.

Study co-author Meghan Butryn, Ph.D and associate professor in the College of Arts and Sciences at Drexel said: Regularly weighing yourself can motivate you to engage in healthy eating and exercise behaviours, because it provides you with evidence that these behaviours are effective in helping you lose weight or prevent weight gain.

Similarly, if you see weight gain on the scale, that information can motivate you to make a change.

Meanwhile, another recent study has revealed that drinking coffee could lead to weight gain.

This is because thecaffeine attaches to adenosine receptors in the body which keeps you awake.

However, the caffeine also decreases your ability to taste sweet things making you crave more sugar than before. This could make you more likely to seek out sweet foods which could mean you pack on the pounds.

Read this article:
Doing this ONE simple thing daily will make you lose weight fast - Daily Star

Read More..

Weight-Loss Win is an original Yahoo series that shares the inspiring stories of people who have shed pounds healthfully.

Folland OConnor is 31 and 51 tall, and she currently weighs 135 pounds. In 2011, she saw an unflattering picture of herself that motivated her to change her lifestyle. This is the story of her weight-loss journey.

The turning point

I hate to say it,but I really never thought my weight was an issue. When I was fat, I never wanted to do anything active, or anything at all really, besides watch TV, eat food, and hang out with my friends. I never had high energy levels or interest in sports when I was bigger, so I never ran into major issues because of my size. What prompted the weight loss was mostly an aesthetic choice. I always wanted to be skinny but never had the willpower to actually get there. I just kind of accepted my body as it was and figured I wasnt built to be skinny. I thought I could never actually lose weight and that I was just built to be curvy or I was big boned.

My parents started expressing their concern for my health more often as I got bigger, but I thought they were just exaggerating and that I was an average weight. Looking back now, I just cant even fathom how I was so ignorant about my size.

I never realized how big I was until I saw a picture of myself from the side. The picture was taken at an event I attended and I happened to be painting something on a canvas when the photo was snapped. I wasnt able to pose or work my angles; it was just a picture of me from the side, not paying attention and I looked huge. The moment I saw that picture I vividly remember thinking, Oh my gosh Im fat. I had this huge epiphany.

I was wearing size 22 jeans, I couldnt buy a shirt in less than an XL, I had to buy bras in a plus-size store, but still, it was seeing myself in that photo that actually hit home. I was 25, 51, 220 pounds, and I was obese.

Folland OConnor saw a photo of herself that inspired her to lose weight.

The changes

Since college, I had always had some diet plan in mind or some workout routine I swore I would finally follow, but I never really committed to anything. I tried to eat healthy for a day or two but quickly fell off the wagon. I had zero self-control and knew absolutely nothing about losing weight or healthy eating.

When I finally accepted the fact that I was fat, I decided to simply start researching diets and weight loss as a whole. It was so overwhelming and complicated. I couldnt figure out whether carbs were bad or good, whether fat made me fat or not, whether artificial sweeteners would kill me, make me skinny or make me bigger.

Working out was a whole other bag of complications. How I should work out. Cardio? Weights? Yoga? I just couldnt get it straight. I decided to find a strict, clean, basic diet plan and just focus on eating first, because, more than anything, I hated working out.

Through my research I found some random site for a naturopath who touted a crazy weight-loss plan, so I met with her and she introduced me to the hCG Diet. Most people will have heard of it by now, and it is pretty controversial, but its what got me on the road to a healthy weight.

For those that dont know, hCG is an extremely strict, very low-calorie diet combined with a hormone shot. It was completely bonkers and probably not the healthiest way for me to lose weight, but it promised immediate results. So I bought all of the ingredients from this holistic voodoo doctor and tried it out.

Folland OConnor initially lost weight with the hCG diet.

Read More

I did two rounds of hCG, losing 60 pounds over the course of about four months. Losing that much weight that quickly was completely surreal and I fell off the wagon pretty fast once the rounds were finished. Over the next year or so I gained 30 back, but my life had been changed forever. I started becoming more active, my self-confidence skyrocketed, and I actually started to realize how unhealthy I was. Even after keeping 30 pounds off, I was still overweight, so eventually I started hitting the gym and actually focused on living a healthy lifestyle. I got my life under control, and my weight followed.

While losing weight, I felt like I could do anything. I realized that everything in my life was able to be changed. I changed careers, left my cheating boyfriend, bought a condo, joined a gym, and started playing roller derby. I felt confident and powerful, and my life was changing drastically in so many positive ways.

Keeping motivated isnt hard when everything in your life is positive. People were constantly complimenting me, my job got easier, I was succeeding in a new sport that I loved, and the weight kept falling off of me.

When I did hit a plateau, I just gave myself a small break, focused on maintenance and then reassessed my diet plan. My new boyfriend was alsovery interested in fitness, and he always had some awesome advice or a new recipe for us to try out together. He kept me strong, confident, and on track through the entire process. Even to this day, he is who I look to for inspiration.

The after

Everything in my life changed. The obvious things of course, my energy levels, my clothing size, and my health, but less obvious things also changed. My self-esteem and confidence levels sky rocketed, and my willingness to take more risks and be more outgoing all changed for the better, but the biggest change I experienced was in how people treated me. People are nicer to me now, they try harder for me to like them, strangers gravitate toward me, and I have to put in much less effort to forge relationships. Its amazing how people treat me like a completely different person, but in the most positive ways.

A few things surprised me about the weight-loss process. It was not actually that hard to lose weight when I was 220 pounds, even though it seemed so daunting at the time. But, with all of the knowledge Ive gained, Ive realized that I was so large I actually had to eat a lot of calories every day to maintain that weight. As soon as I started eating less, I lost weight. It was truly quite simple. Its much harder to cut weight now that Im smaller every calorie counts.

Folland OConnor was surprised by what changed in her life after losing weight.

I lost ring sizes and a whole shoe size! I knew I was losing weight, and a lot of it, but it never occurred to me that my fingers and my feet may have also been carrying extra weight. I went from a size 9 ring to a size 6.5, and I went from a size 8 1/2 shoe to a 7 1/2 shoe. That still totally amazes me.

The maintenance

I follow the Strong Lifts weight routine and hit the gym three to fourtimes per week. I also play competitive-level roller derby with the Anarchy Angels Roller Derby team and practice on skates two times per week. I eat a low-carb diet and try to keep my calorie intake around 1,200. That might sound low, but keep in mind, Im only 51.

I eat with purpose and awareness. No more mindless snacking unless Im on a cheat meal and, yes, I allow myself cheat meals not cheat days every so often. I live life with moderation and try not to reward myself with food. Whatever I do eat, I really try to enjoy. Dieting doesnt need to mean bad food.

Folland OConnor is inspired by her boyfriend.

My boyfriend has lost 55 pounds himself and trains harder than anyone Ive ever seen. He wants to be the best version of himself and pushes me to be the best version of myself. We make tons of different low-carb recipes together and support each other through all of our transitions. He keeps me on the right track and always pulls me back on that wagon when Im distracted by Thai food and doughnuts.

The struggles

Obviously, I have impulse-control issues with food. You dont become 220 pounds without having some issues with eating. I am still constantly fighting my own urges when it comes to my diet. To this day, I can easily out-eat a grown man (including my 64 boyfriend). If I let myself go, stop being diligent, or give up my gym routines, I will quickly lose control again. It is a constant battle, but it is worth it because every pound I lose and every pound I keep off means one more minute on this earth living my life to its fullest.

Advice

Its calories in versuscalories out. At the end of the day, diet was always the most important part. No matter how hard I tried, I could never outrun my fork. I work out, but thats mostly because it makes me better at sports. Diet to look good, lift weights to look good naked.

All photos courtesy of Folland OConnor.

Need more inspiration? Read about our other weight-loss winners!

Weight-Loss Win is authored by Andie Mitchell, who underwent a transformative, 135-pound weight loss of her own.

Have a weight-loss win or beauty story to share? We want to hear it! Tell us at YStyleBeauty@yahoo.com.

Read more from Yahoo Beauty + Style:

Follow us onInstagram,Facebook, andPinterestfor nonstop inspiration delivered fresh to your feed, every day. For Twitter updates, follow@YahooStyleand@YahooBeauty.

More here:
The hCG Diet helped this woman lose 85 pounds, but this inspired her to keep the weight off - Yahoo Health

Read More..

More than once I have been out with a confident woman who has had her self-esteem sabotaged by a comment about her weight. At my pudgiest, Ive never been so verbally assaulted.

To paraphrase Oscar Wilde, many women talk about their looks and weight; that is their tragedy. Few men do; thats theirs. Comedian Amy Schumer has addressed this dichotomy, perhaps most pointedly on the Twelve Angry Men episode of Inside Amy Schumer, but she wasnt the first.

Margaret Cho, in her groundbreaking monologue stage show Im the One that I Want (filmed 2000), discussed the difficulties she faced because of her weight while starring in the 1994 sitcom All-American Girl. As she put it, she had to lose weight to play the role of herself (as opposed to Drew Carey, who, Cho pointed out, got her old time slot and some of the same sets for his subsequent show, but didnt face the same pressure to slim down). In fact, she lost so much weight so rapidly through an unhealthy diet and fear that she says she suffered kidney failure. And still she wasnt considered thin or even a healthy weight for her height and frame.

To paraphrase Oscar Wilde, many women talk about their looks and weight; that is their tragedy. Few men do; thats theirs.

Cho was a victim of fat shaming including by her own network employers, mostly men and that was in the era before Facebook and Twitter. Considering the abuse recently heaped upon Leslie Jones (of the 2016 Ghostbusters reboot and Saturday Night Live) for her appearance, Cho was comparatively lucky.

According to the U.S. National Center for Health Statistics, 19881994, more women than men (ages 20 and older) think they are overweight or obese, regardless of whether they are or not. Thats partly realistic more Americans of either gender are overweight than realize it but it also reflects the extra pressure women face to look good.

Fat shaming can lead to illegal drug abuse and diet pill addiction Cho abusively used drugs and alcohol after her sitcom was canceled; the criticism of her body arguably was a contributing factor either as a coping mechanism or, especially in the case of diet pills, as a means of losing weight.

Diet pills work by:

Just because the drugs help you lose weight doesnt mean they are healthy or safe. The earliest anti-obesity medications were just laxatives or purgatives, thus preventing absorption of calories by removing them from the body as quickly as possible. But this can result in a dangerous loss of potassium in the body, affecting the heart and other muscles.

Cocaine, a stimulant, may help you lose weight, but it is illegal, dangerous, and addictive. It can permanently damage your metabolism. Some legal stimulants have a similar weight-reducing effect, but are only recommended for short-term use because of possible side effects. A diet pill addiction increases the likelihood of such side effects.

Even effective anti-obesity medications have been withdrawn from the market or have been rejected by the U.S. Food and Drug Administration because of concerns that they can do more harm than good. Many so-called diet pills and weight loss supplements, especially those sold on the web or by mail, effective or not, can be deadly. For one thing, they may be adulterated or not contain the ingredients they claim because there is no government regulation. If they do help you lose weight, cardiologist Arthur Agatston warned Prevention, it could be due to a stimulant whose safety is unproven, and they may cause unpleasant, even dangerous cardiac side effects.

At the end of her monologue, Cho said, Its so wrong that women are asked to live up to this skinny ideal that is totally unattainable. For me to be 10 pounds thinner is a full-time job, and I am handing in my notice. Not that she was against losing weight. She dropped quite a few pounds later, and even performed burlesque in the name of body acceptance.

In general, it is healthier to be thinner than overweight, but its never appropriate to fat shame someone because (despite what Milo Yiannopoulos posts on Breitbart) not only isnt it nice, it doesnt work. Some men forget this, not realizing or not caring that it is easier for men to lose weight because in general we have more muscle mass and therefore faster metabolisms.

Cho arguably lost weight after professional success and personal happiness, not because Internet and real-world trolls called her fat.

A healthier way to lose weight than a diet pill addiction is physical activities such as strength training, which also have the benefit of improving mood by releasing endorphins and preventing osteoporosis by strengthening bones. Just dont let it turn into an addiction to exercise.

Photo by Hamza Butt

Read this article:
Fat Shaming is a Just Another Form of Hate - The Good Men Project (blog)

Read More..

I too have raided the refrigerator, watched a movie, only to wake up to an empty bag of chips on the floor, an open bottle of wine on the counter, and none of it within immediate recall after being confronted by my wife.Usually I can remember bits and pieces of the night before.The adverse effects wear off.I typically can wake up within 4 hours and not feel any lingering effects, which is useful if I'm trying to nap before starting a night shift.Then I take a half tab before going to bed in the morning.

I've been on Ambien most nights for the past 6 years, mostly because of shift work, flipping between night and day shifts, living in like a perpetual jet lag without any of the benefits such as collecting fond memories and exotic passport stamps...The first night I took Ambien I was amazed at what a good night's sleep I had.Since then, it hasn't been as profoundly restorative, but mostly better than the alternative.It ***** not sleeping.I'm aware that Ambien is only recommended for 7-10 days, and the clinical trials were in numbers of weeks, not years.Not much is really known about the long term effects, and it needs to be scrutinized.Unfortunately, I think it can be difficult to remove factors that contribute to cognitive impairment that exist alongside Ambien use, such as depression, anxiety, caffeine use, diet, lack of exercise, and sleep deprivation itself.

I have periodically gone Ambien-free, but only for 2-3 nights at a time, which is only possible when I am caffeine free, and not subjected to the erratic schedule, and when I can exercise regularly.I had to re-learn how to sleep, and then only when completely off stimulants, and on a lighter work schedule.The longest I was off Ambien in the past 6 years, was maybe a week.Then there is coffee.There is nothing like it for energy and mood elevation when sleep deprived, or not wanting to be at work,or craving sleep, or staving off depression.Wake at 7am, go to work at 4 or 6pm, and don't get home and in bed until 3 or 5 am.Or maybe go to work at 11pm, get to sleep at 10am, then get up for work at 5:30am a couple of mornings later. I do that for a week, and my mind starts going to muck, so I'm back on the mud.My mantra has been, "there is only one thing worse than no coffee, that's not enough of it". That in part has fueled my Ambien use, or maybe I should say addiction, and/or dependence.

But recently, my concentration has been off, I'm having decreased fluency of speech, and it feels like there is something interfering with my thought process.My depression has been worse.Holy ****, have I screwed myself for all these years taking Ambien?How much is it all the other stress in my life?

An earlier post brought up a valid point, one which is confounding.The causes of insomnia, varied as they may be, can contribute to memory loss.In my case, it's a stressful job, caffeine use, occasional alcohol, chocolate, crazy work hours, lack of exercise, marital discord, parenting, it's is a no-brainer.Remove all that crap and I'll sleep like a baby, right? Still, it seems like a chicken or the egg.I can't think clearly, it bugs the **** out of me, and I'm depressed about it.

What causes what?Is it just a prolonged case of caffeine withdrawal?Is it early dementia?Is it the Ambien?My mother had Alzheimer's.My dad was a brilliant engineer, test pilot, CEO, entrepreneur, public speaker and has never taken Ambien in his life, yet he is now cognitively impaired.

If depression can cause memory loss and cognitive impairment, wouldn't the combination of sleep deprivation, anxiety, and depression do the same?And what if sleep deprivation can cause or exacerbate anxiety and depression?None of us need a pharmaceutical brain f*&k on top of that.I feel for those who left or lost their jobs.This past week I felt like resigning, but I can't afford to retire or take a cut in pay.And I'm up at 4 am blogging instead of sleeping in on father's day.I should mention, watching TV or surfing the web won't help me get to sleep.God help us all if Ambien turns out to be the dementing poltergeist we fear it might be.All I can do is stop taking it, deal with insomnia by optimizing sleep hygeine and hope for the best.

Read the original here:
short term memory loss from long term Ambien use ...

Read More..

Dieters who lose varying amounts of weight each week may not shed as many excess pounds as people who consistently lose the same amount week in and week out, a U.S. study suggests.

Researchers examined data on183 overweight and obese adults who participated in a weight loss program with meal replacements provided along with goals for calorie monitoring and exercise.

After two years, the dieters who had the most consistent weight loss during the first three months of the program shed more excess pounds than the people who initially had more fluctuation, researchers report in the journal Obesity.

While the study cant explain whether or how consistency in weekly weight loss might contribute to success, its possible that different approaches to dieting played a role, said study co-author Michael Lowe, a psychology researcher at Drexel University in Philadelphia.

Those who lose weight steadily may have had more consistent eating and exercise habits before they joined our program and continued with that pattern as they cut back on calories and exercised more, Lowe said by email.

Those with more variable patters may be trying to lose weight as quickly as possible - so they sometimes have big weight losses, but this leaves them starving and unable to stay on their diet for a week or so, Lowe added. They regain some of their weight, get upset, and try to lose as much as they can again.

At the start of the study, participants were 51 years old on average and typically obese. The majority were white, and most were women.

Overall, participants weekly weight loss tended to vary by about 1.09 pounds during the first six weeks and by 1.33 pounds during the first 12 weeks of the study.

Women tended to be more consistent dieters than men, with less variation from one week to the next at both six weeks and 12 weeks.

The researchers found that higher weight variability during the initial six and 12 weeks of weight loss treatment predicted poorer subsequent, long-term weight control at one year and at two years.

For example, someone who lost four pounds one week, regained two and then lost one the next tended to fare worse than someone who lost one pound consistently each week for three weeks.

Interestingly, individuals who reported lower emotional eating, binge eating and preoccupation with food at the start of the study showed higher weight variability and less weight loss overall.

This suggests that initial weight change, rather than relationships with or behaviors toward food, is much more important in predicting who will succeed in weight loss and maintenance, the authors conclude.

Its also possible that variation in weight loss from one week to the next slows down overall weight loss, making it harder for people to achieve long-term weight loss goals, said Susan Roberts of the USDA Nutrition Center at Tufts University in Medford, Massachusetts.

So people who are on their program some weeks but not others will inevitably lose less weight because you cant really catch up in the sense of making up bad weeks, Roberts, who wasnt involved in the study, said by email. At best, you can only get back on track.

See the article here:
Steady may win the weight-loss race - ABS-CBN News

Read More..

Three independent studies from three pharmaceutical companies suggest a new way to suppress diet and lose weight in mice, rats, and monkeys.

Camilo Torres/iStock Photo

By Ryan CrossAug. 30, 2017 , 1:54 PM

Weight loss seems to come easiest to those who want it least. Every year, hundreds of thousands suffer from the loss of appetite that comes with tumor-induced anorexia, which can accompany many late-stage cancers. Now, researchers from three major pharmaceutical companies have independently published papers showing that the culprit behind this conditiona protein called growth differentiation factor-15 (GDF15)helps mice, rats, and monkeys lose weight without any apparent side effects.

The idea of having another medication to add to our armamentarium is exciting news, says Katherine Saunders, an obesity medicine physician at Weill Cornell Medicine in New York City who was not involved with the work. There are currently five U.S. Food and Drug Administrationapproved obesity medications for long-term weight management, which can help patients lose 5% to 8% of their body weight on average. Thats very limited, Saunders says, adding that many drugs used to treat obesity dont have the same level of specificity as GDF15.

GDF15s potential as a weight-loss agent was first discovered by Samuel Breit, an immunologist and physician at St. Vincent's Hospital in Sydney, Australia. He saw levels of the protein rise 10 to 100 times higher than normal during tumor-induced anorexia in mice with prostate tumors and in humans with advanced prostate cancer. Breit also showed that GDF15 likely exerts its effects through the brainthough he says that until now the proteins target has befuddled scientists.

To find that target, Sebastian Beck Jrgensen, a diabetes and obesity researcher at Novo Nordisk in Maaloev, Denmark, and colleagues screened more than 2700 proteins that reside in human cell membranes, where they receive molecular signals from outside the cell and transmit their messages inward. Among all these possible partners, GDF15 bound to a single protein receptor called the GDNF family receptor-like (GFRAL), whose function was previously unknown, the team reports this week in Nature Medicine.

Next, the researchers searched through an entire mouse brain for cells whose GFRAL gene was turned on. Surprisingly, it was found only in two regions of the brain: the area postrema, known as the vomit-inducing center, and the nucleus of the solitary tract, which houses neurons involved in many behaviors, including ones implicated in appetite regulation. That would normally be a problem for drug development, because most receptors are walled off by the blood-brain barrier, a system of cells that keeps drugs, toxins, and microbes out of the brain. But because these two GFRAL-containing regions are part of a small portion of the brain that sit outside the barrier, Jrgensen and colleagues think theyve got a good drug target. [It] turns out to not be as complicated as we were anticipating, he says.

To prove that GFRAL was necessary for GDF15-powered weight loss, the team created a strain of mice that couldnt produce the receptor, which they then compared with a group of regular mice. When fed a high-fat diet for 16 weeks, all the mice doubled in weight, from about 20 to 40 grams. Daily injection of GDF15 for 4 weeks reduced the regular mices food intake and thus helped them shed about 5 to 10 grams each, a significant fraction of their body weight. The mice without the GFRAL receptor didnt lose any weight when given GDF15, but otherwise appeared similar to regular mice.

In another experiment with rats, a higher daily dose of GDF15 caused their food intake to plummet by 75%, from 20 to 5 grams of food per day. Rats whose diets were restricted to the same small portions of foodbut who were not on GDF15lost similar amounts of body weight and fat, which supports the idea that GDF15 works primarily by suppressing appetite, and not by boosting metabolism and burning calories.

Papers also published this week in Nature Medicine by Eli Lilly & Company in Indianapolis and Janssen BioTherapeutics in San Diego, California, also independently identified GFRAL as the receptor of GDF15, with similar diet-suppressing results. Additionally, Janssen researchers created a long-lasting version of GDF15 that was given to cynomolgus monkeys. It remained active in their bloodstream for 4 weeks and helped them drop 4% of their body weight.

We are very glad to see the major findings in all three papers are consistent with each other, says Xinle Wu, who led the research team at Eli Lilly. A spokesperson for Janssen declined an interview request.

One potential concern about GDF15 is that it acts on the vomit-inducing center of the brain. Janssen researchers noted no signs of nausea, uneasiness, or vomiting when GDF15 was given to monkeys. But Richard Palmiter, a neuroscientist who studies the regulation of appetite at the University of Washington in Seattle, says, Since you cant ask animals how they feel, there is a risk that this drug would make people feel sick rather than satiated.

So far, Jrgensen says his team hasnt noticed any side effects from GDF15, which can occur when a drug binds multiple targets, or when a receptor is found throughout the body. So far, GDF15 seems selective to GFRAL, which itself is highly localized to two small brain regions. He adds that Novo Nordisk is tweaking GDF15, ideally to exert a stronger and longer-lasting effect. This modified form of the protein is what will likely be tested in human clinical trials, whenever they occur: All three companies are hush-hush on time frames. Jrgensen anticipates a GDF15-based drug would be most effective in combination with existing or future obesity treatments.

W. Scott Butsch, an obesity medicine physician at Massachusetts General Hospital in Boston, agrees. (Butsch is part of Novo Nordisks clinicians advisory board, but was not involved nor aware of its research on GDF15.) Obesity is a complex disease with no one-size-fits-all treatment. Combination therapy is the future, he says. For instance, GDF15, which dampens appetite, could be used additively or synergistically with another drug that boosts metabolism. Weve moved beyond thinking that one drug will win the jackpot and cure everyones obesity.

See the article here:
Cancer-induced anorexia inspires potentially powerful antiobesity drug - Science Magazine

Read More..

AUSTIN, Texas--(BUSINESS WIRE)--Apollo Endosurgery, Inc. (Apollo) (NASDAQ:APEN), a global leader in less invasive medical devices for bariatric and gastrointestinal procedures, today announced CE (Conformit Europene) Mark approval for the ORBERA365 Managed Weight Loss System.

The ORBERA365 Managed Weight Loss System doubles the indwell period of the #1 intragastric balloon in the world from 6 months to a 12 month treatment period. The approval enables Apollo to market and sell the ORBERA365 Weight Loss Balloon in European Union and the European Economic Area member countries. The Company expects ORBERA365 to be commercially available starting in the fourth quarter of 2017.

Ive been using ORBERA since 1999 and have helped thousands of patients lose weight with my ORBERA program. Now with ORBERA365 patients will have the possibility of getting better weight loss results because in my experience the longer the treatment the more weight patients tend to lose. Actually, using ORBERA365 our patients will now have twice as long to change their eating behaviors and ensure long lasting results, said Professor Alfredo Genco, Sapienza University, Rome, Italy.

The CE Mark approval of ORBERA365 has been a significant accomplishment for Apollo and involved a comprehensive review of clinical and non-clinical data by a regulatory body in a market with deep understanding and experience with intragastric balloon therapy. Obtaining CE Mark approval now for ORBERA365 is a strong testimony of the relevance and significance of more than a decade of the ORBERA systems safety and efficacy data as supported by more than 277,000 distributed implants and 230 published peer-reviewed papers, said Todd Newton, CEO of Apollo Endosurgery.

About ORBERA365

ORBERA365 is an incision-less, non-surgical weight loss solution designed for adult patients suffering from obesity, who are not appropriate for or considering invasive surgery, but for whom diet and exercise or pharmaceutical interventions have not worked.

In a non-surgical (endoscopic) procedure, the thin and deflated ORBERA365 balloon is placed into the stomach. It is then filled with saline until its about the size of a grapefruit. The procedure typically takes about 20 minutes and the patient can generally go home a few hours later. After up to twelve months, through another non-surgical procedure, the ORBERA365 balloon is deflated and then removed.

Once the balloon is in place, the patient works with their physician and their staff in a formal lifestyle modification program to meet their long-term weight loss goals. Coaching takes place over 12 months while the balloon is in place. The program is designed to help the patient develop sustainable, healthy habits that will help keep weight off over time.

For additional information regarding ORBERA365, please visit http://www.orbera.com/uk-ireland/.

For full safety information please visit http://www.orbera.com/uk-ireland/dfu.

About Apollo Endosurgery, Inc.

Apollo Endosurgery, Inc. is a medical device company focused on less invasive therapies for the treatment of obesity, a condition facing over 600 million people globally, as well as other gastrointestinal disorders. Apollos device based therapies are an alternative to invasive surgical procedures, thus lowering complication rates and reducing total healthcare costs. Apollo's products are offered in over 60 countries today.

Apollos common stock is traded on NASDAQ Global Market under the symbol "APEN." For more information regarding Apollo Endosurgery, go to: apolloendo.com.

2017 Apollo Endosurgery, Inc. All rights reserved. Any third-party trademarks used herein are the property of their respective owners.

Read the original here:
Apollo Endosurgery Announces CE Mark Approval for the ORBERA365 Managed Weight Loss System, Expanding ... - Business Wire (press release)

Read More..

Low-carb diets have become extremely popular among the millions looking for the solution of losing weight and keeping it off.

While the South Beach Diet isn't as strict as many low-carb diets, it does limit the amount of carbs you can eat and encourages adding more healthy fats to your diet.

The following is everything you need to know to decide whether the South Beach Diet is right for you:

The South Beach Diet was created by a cardiologist in 2003, and it's considered to be a modified low-carbohydrate diet,according to U.S. News & World Report. It's based on the idea that carbs and fats can be either good or bad. If you decide to follow the South Beach Diet, you'll probably be getting fewer carbs and more protein and healthy fats than you're used to eating.

The diet is broken down into three phases, asoutlined by the Mayo Clinic:

Phase 1 This stage lasts only two weeks and is the most restrictive. Almost all carbs are eliminated during this phase, which is designed to jump-start weight loss and eliminate your cravings for refined starches and foods that are high in sugar.

Phase 2 This long-term weight loss phase is less restrictive and should be followed until you reach your goal weight. You can add in some, but not all, of the foods that are restricted in the first phase.

Phase 3 After you've reached your goal weight, you're supposed to take the principles learned in the first two phases to eat healthier for the rest of your life. Most foods are OK to eat in moderation at this point.

The diet also encourages exercise, includingwalking and exercises designed tostrengthen your core.

If you're following the South Beach Diet, you'll be encouraged to eat plenty of vegetables.For the AJC

Foods that are encouraged

The South Beach Diet calls for plenty of the following types of foods:

The Mayo Clinic says the South Beach Diet can yield some health benefits. If you eat more healthy carbs and more healthy fats in the long-term, you can see health benefits that go beyond weight loss, such as lowering your cholesterol levels.

It views the diet as generally safe, but cautions against restricting carbohydrates too severely. This can cause ketosis, a process caused by insufficient sugar in your body. Without enough sugar to use for energy, your body will break down stored fat, and you can experience ketosis and its side effects, including nausea, headache, mental fatigue and more.

In addition,experts told U.S. News & World Report that the first part of the diet is a little heavy on fat and that phases one and two may not contain enough carbs. They also caution people with kidney problems that the diet may not include enoughpotassium.

However, it also said that you should feel full while you're following this diet, because it contains plenty of fiber. This is also true since snacks are encouraged in order to help prevent you from getting hungry.

More here:
Cutting the carbs: Everything you need to know about the South Beach Diet - Atlanta Journal Constitution

Read More..

Floyd Mayweather, Jr. beat Conor McGregor in a boxing match this weekend in Vegas. However you feel about either boxer, or the money- and testosterone-drenched exercise that the two took part in, Mayweather remains undefeated, the best in the ring. As for his preparation and diet leading up to the fight, like any legitimate athlete, he is fueled by a steady supply of spaghetti bolognese.

Mayweather's chef, J. Santiago, gave TMZ the run-down on his diet before matches, and apparently the boxer is so "obsessed" with spaghetti bolognese he ate it almost every day before facing McGregor. Mayweather also typically eats protein-rich breakfasts that include eggs, home fries, grits, pancakes, and meats like bacon, turkey sausage, turkey ham, and turkey kielbasa.

Advertisement - Continue Reading Below

To make weigh-in on Friday, Mayweather had to forgo the breakfast spread, sticking to just two bananas and water. That was enough to slim him down to 149.5 pounds, just in time to fight Saturdaythe limit was 154 pounds.

McGregor, who weighed in at 153, said at the time, "[Mayweather] looks like dog shit, you know that. He looks blown up, full of water. He's not going to keep my pace. Trust me on that. That's the worst shape I've ever seen him. He looks blown out, out of shape. I'm going to breeze through him. Trust me on that." This obviously was not the case, thanks to spaghetti bolognese, protein, and the most lucrative boxing match agreement to ever befall the two totally legitimate fighters.

Go here to read the rest:
Floyd Mayweather Prepared for His Historic Fight by Eating Pasta - Esquire.com

Read More..

Contact Us Today

Page 1,804«..1020..1,8031,8041,8051,806..1,8101,820..»

Home » Page 1804