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Very few men relish the thought of their hair deliberately falling out as they age. Up to 20% of men beginning already in their twenties will have male pattern baldness, with the rate increasing among men with each decade of life. Whether a man tries to fight his baldness in every way he can or embraces it with pride, what is known is the possibility of a potential connection between male pattern baldness and prostate cancer.

Prostate cancer is the second most common type of cancer and the fifth leading cause of cancer-related death in men. It occurs more frequently in the developed world but is the most common cancer in men in 84 countries.

A recent study found that male pattern baldness appears to be a strong and independent risk factor for prostate cancer. The study published in the Canadian Urological Association Journal enrolled 394 patients who were to have a prostate biopsy but with no history of prostate cancer. Researchers also noted their male pattern baldness which was determined by looking at a validated Norwood score rating it as either no balding, frontal balding, mild vertex balding, moderate vertex balding, or severe vertex balding.

The connection between male pattern baldness and prostate cancer

Androgenic alopecia, or male pattern baldness, is the most common type of hair loss in men. More than 50% of all men over the age of 50 will be affected by male pattern baldness to some extent.

The cause of baldness in men usually is a family history of baldness or the male sex hormones call androgens. Androgen is a Greek word meaning man-maker which definitely rings true for the male species. The most potent androgen is testosterone which is responsible for deepening a mans voice, increasing his muscle mass, and strengthening his bones.

Testosterone can also be converted into another type of androgen called dihydrotestosterone (DHT). DHT can cause acne in addition to putting hair on a mans chest but with a tendency to reduce hair on a mans scalp. Even though male pattern baldness and prostate cancer are two separate conditions, DHT stimulates the growth of prostate cells that contributes to benign prostatic hyperplasia (BPH) in older men.

The relationship between prostate cancer and male pattern baldness is the fact that prostate cancer is a hormone-dependent disease and most hair loss in men is caused by androgenic alopecia due to the hormones of androgens. What are known risk factors for prostate cancer and male pattern baldness is aging of men and androgens, with androgens implicated in the development of both conditions.

Results of the study

Of the 394 male participants, 194 men or 49.2% had cancer and 110 or 27.9% had a Gleason score of 7 or higher at biopsy. The data analysis showed that the higher the grade of male pattern baldness as measured by the Norwood scale, the higher the risk of developing prostate cancer. It was also found that higher-grade prostate cancer was associated with a higher grade or more severe type of baldness which was not found with the milder forms of baldness.

Male pattern baldness and prostate cancer may share the same manner of the development of the disease. Some of the proposed causes behind both prostate cancer and male pattern baldness are androgens, insulin-like growth factor 1 (IGF- 1) and micro RNAs. It is also known that men with vertex baldness have a significantly higher association of free testosterone, DHT and a DHT/testosterone ratio. In addition men with high levels of IGF-1 have been shown to have an increased risk of developing prostate cancer when compared to men with low IGF-1. There was no association between male pattern baldness and prostate volume.

Findings from a larger study

Another study in 2016, published in the American Journal of Epidemiology followed a sample of 4,316 men of which 107 deaths were attributable to prostate cancer, did make links between specific types of hair loss and those who developed the disease. The researchers explained that they found an increased risk of aggressive prostate cancer only in men with a very specific pattern of hair loss baldness at the front and moderate hair-thinning on the crown of the head. Other types of hair loss patterns appeared unaffected.

The scientists with the study hypothesized that androgens such as testosterone, are thought to underlie both male baldness and prostate cancer progression. Depending on the pattern of male baldness appeared to determine the aggressiveness of prostate cancer.

In conclusion

At this time, it is too early to definitively state that male pattern baldness can be considered an independent risk factor for prostate cancer. It appears that male pattern baldness could be a strong independent risk factor for prostate cancer but both studies did state that further research is necessary before it can be validated as such.

At this time, men with any degree of baldness should not be additionally concerned about their individual risks of developing or dying from prostate cancer as these results should be interpreted in a cautious manner. But men with concerns should discuss this with their physician about when and how frequently to undergo prostate cancer screening.

Patients newly diagnosed with prostate cancer can contact world-renowned prostate cancer surgeon and urologic oncologist, Dr. David Samadi. For a consultation and to learn more about prostate cancer risk, call 212-365-5000.

Dr. Samadi is a board-certified urologic oncologist trained in open and traditional and laparoscopic surgery and is an expert in robotic prostate surgery. He is chairman of urology, chief of robotic surgery at Lenox Hill Hospital. He is a medical correspondent for the Fox News Channel's Medical A-Team. Follow Dr. Samadi on Twitter, Instagram, Pintrest, SamadiMD.com and Facebook

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The link between baldness, testosterone and prostate cancer | www ... - Western Queens Gazette

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July 12, 2017 - By Winifred Garcia

Investors sentiment increased to 1.36 in 2016 Q4. Its up 0.20, from 1.16 in 2016Q3. It increased, as 10 investors sold AllianceBernstein Global Hgh Incm Fd Inc shares while 18 reduced holdings. 10 funds opened positions while 28 raised stakes. 13.43 million shares or 5.51% more from 12.73 million shares in 2016Q3 were reported.United Financial Advisers Llc stated it has 20,539 shares. Bb&T Limited Liability accumulated 11,950 shares. Live Your Vision Ltd Co owns 921 shares. Cetera Limited Liability Com has invested 0.01% in AllianceBernstein Global Hgh Incm Fd Inc (NYSE:AWF). Citigroup has 0% invested in AllianceBernstein Global Hgh Incm Fd Inc (NYSE:AWF). Next Gp holds 0% or 1,800 shares. 741 are owned by Fifth Third Financial Bank. Moreover, Guggenheim Capital Ltd Liability Co has 0.01% invested in AllianceBernstein Global Hgh Incm Fd Inc (NYSE:AWF). Planning reported 35,399 shares. Hl Financial Ltd Liability Company reported 34,420 shares. Commonwealth Equity accumulated 74,193 shares. Sanctuary Wealth Ltd Limited Liability Company holds 0% or 431 shares. West Oak Limited Liability Corp holds 400 shares. Royal Bank & Trust Of Canada owns 0% invested in AllianceBernstein Global Hgh Incm Fd Inc (NYSE:AWF) for 379,340 shares. Sunbelt holds 2,813 shares.

The stock of AllianceBernstein Global Hgh Incm Fd Inc (AWF) shows a multiple tops pattern with $14.03 target or 9.00 % above todays $12.87 share price. The 6 months chart pattern indicates low risk for the $1.11 billion company. It was reported on Jul, 12 by Finviz.com. If the $14.03 price target is reached, the company will be worth $99.90M more.Multiple tops are chart patterns with decent performance in a bull market. The failure rate is higher but the average decline is reasonable. Back-tests of such patterns show that the break even failure rate is 10%, the average rise: 19%, the throwback rate: 61% and the percentage of stocks meeting their price targets: 40%.

The stock increased 0.31% or $0.04 on July 11, reaching $12.87. About shares traded. AllianceBernstein Global Hgh Incm Fd Inc (NYSE:AWF) has risen 7.26% since July 12, 2016 and is uptrending. It has underperformed by 9.44% the S&P500.

More important recent AllianceBernstein Global Hgh Incm Fd Inc (NYSE:AWF) news were published by: Seekingalpha.com which released: ACG Or AWF: Which Is The Better Fund? on May 19, 2015, also Seekingalpha.com published article titled: AllianceBernsteins Global High Income Fund Isnt That Attractive To Buy, Marketwatch.com published: AllianceBernstein Global High Income Fund Inc. on June 11, 2011. More interesting news about AllianceBernstein Global Hgh Incm Fd Inc (NYSE:AWF) was released by: Prnewswire.com and their article: AllianceBernstein Global High Income Fund, Inc. Monthly And Special Distributions with publication date: December 14, 2016.

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It Seems AllianceBernstein Global Hgh Incm Fd Inc (AWF) Will Go Up. Formed A Few Months Multiple Top Chart Pattern - Weekly Register

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For Ruth Gottlieb, 82, and Jean Timper, 85, and members at the East Brunswick Senior Center in New Jersey, exercise is the high point of their day. What gets them most excited? Line dancing.

I even dance around the house. When Im vacuuming or cooking, I just stop and dance around and stretch. I like to be flexible, says Gottlieb, a former teacher who says her only regular exercise before retirement was running after students.

Since 2002, the friends have kept moving through programs designed by Rutgers Universitys Center for Exercising and Aging, in which students lead seniors in activities ranging from strength training to aerobics. If I had not been exercising all these years, I dont think Id be here or doing as great as I am, says Timper.

The center, which celebrates 15 years this year, was founded by Susan Kaplowitz, a teaching professor in the De-partment of Kinesiology and Health at Rutgers School of Arts and Sciences. As a personal trainer specializing in older adults, Kaplowitz realized that her students primarily exercise science majors would benefit from a course that taught them the importance of exercise in the aging population.

I wanted to provide a course that would prepare them for careers that involved geriatrics, she says. Plus, I thought it would be a great way to apply our knowledge to benefit the local community.

Kaplowitz launched the program with the participation of her own clients as she reached out to local senior centers and assisted living facilities, such as the East Brunswick Senior Center and Monroe Village in Monroe Township. The organizations partner with the program by allowing students to work with their members on-site or sending seniors to gyms on the Cook/Douglass campus for exercise classes throughout the year.

Seniors visit centers mainly to socialize, Kaplowitz says. Its an important part of their day. The program allows them to socialize and build their self-confidence as they see their strength improve. Many of our participants have not exercised before, especially in strength training.

Exercise helps older adults maintain daily functions, Kaplowitz notes. The most important exercises focus on the lower body to improve balance since seniors are prone to falls, she says. Cardiovascular exercise is also essential. As people age, muscle mass decreases and body fat composition increases, which can lead to conditions like diabetes. Car-dio can improve body composition and endurance and allow seniors to perform daily tasks without losing breath.

Strength training improves flexibility; when seniors keep moving, their joints stay mobile, helping to prevent osteoarthritis and assisting them in activities like moving their head easier when driving.

Ive seen many 80-year-olds who are more fit than 50-year-olds. It doesnt matter how athletic you once were, when your body ages, you need to exercise to maintain it, says teaching assistant Bella Bulsara, who will graduate this spring with a bachelors of science degree and continue on to graduate school to become a physical therapist. The most important goal is to preserve the ability to perform simple tasks, like lifting your arms and walking, without losing breath. Each person has his or her own constraints. The students learn how to tailor exercises to the individual, even when lead-ing a large group.

Last year, the center began a collaboration with Rutgers School of Health Professions, in which Aging Track program director Tracy Davis brings her perspective as a researcher in gerontology as an instructor and guest lecturer. In the future, Kaplowitz envisions more collaborations with the school.

The students perform community outreach as well. Since 2009, they have helped supervise the New Jersey Senior Olympics in Woodbridge and participated in the Middlesex County Run/Walk by hosting programs on balance, performing fitness tests and offering games.

I bubble over when I exercise with the students, says Millie Holder, 93, a resident at Monroe Village. They give great pointers. Its so important to keep as active as possible for your ability even if youre just moving your fingers. The students help me zero in on arthritis; I roll a ball up my arm with one finger, squeeze a ball or use stretch bands, but chair aerobics is my favorite.

Exercise has improved Holders stamina. I used to think it was such long walk to my apartment, she says.

Now, I run from my home to the auditorium. Being active every day is the best thing that has ever happened to me.

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Exercise program sparks new life in aging adults - Northwest Boomer and Senior News

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As Georgias top public health official, Brenda Fitzgeraldled the fight against childhood obesity in a state with one of the highest rates in the country.The program there, funded in part by the Coca-Cola Foundation, emphasizes exercise and makes little mention of the problems with sugary soft drinks putting the effort at odds with research and the positions of many experts.

Now that Fitzgerald is director of the Centers for Disease Control and Prevention the countrys top public health official some public health advocates are concerned that she could incorporate Georgia's approach into the national battle against obesity.

We hope Dr. Fitzgerald, as head of CDC, avoids partnering with Coke on obesity for the same reason she would avoid partnering with the tobacco industry on lung cancer prevention, said Jim OHara, director of health promotion policy at the Center for Science in the Public Interest.

Public health advocates and researchers have characterized Coca-Colas strategy as deflecting public attentionfrom the links between sugary drinks and a host of health problems, including obesity, diabetes and heart disease, by focusing on exercise and offering grants to buy friends and silence potential critics, OHara said.

To be sure, exercise and physical activity are beneficial for a broad range of health conditions.

Im totally for physical activity programs, said Marion Nestle, a nutrition professor at New York University. Unfortunately, they dont do much for obesity. It takes a lot of activity to compensate for excess calories.

Fitzgerald, who is a physician, was named director of the Atlanta-based CDC last Friday. Agency officials said she was not available for interviews this week. Cokes funding of the Georgia program was first reported in the Intercept.

She began serving on Georgia's newly created advisory council on childhood obesity after becoming commissioner of the state's public health department in 2011. The council is a public-private partnership with members from government, academia, philanthropy and business, and in the past, its members have included two executives from the Coca-Cola company.

The council's program, Georgia SHAPE, launched in 2012. The state ranked second in the nation for childhood obesity that year. It currently ranks 17th, according to the Trust for America's Health's 2016 obesity report.

Since its start, Georgia's special initiative has received more than $57 million to fight childhood obesity through promotion of nutritious foods and physical activity, according to a state public health department spokeswoman.

The spokeswoman said funding sources include federal grants, in-kind services and private grants and sponsorships from Georgia businesses and organizations such as the Coca-Cola Foundation, Royal Foods, Centene/Peach State, and the Arthur M. Blank Family Foundation. A spokesman for Coca-Cola said the foundation has provided $1 million in grants.

Theprogram encourages elementary schools to add 30 additional minutes of daily exercise. In an April 2013 column stillfeatured on Coca-Colas website, Solving Childhood Obesity Requires Movement, Fitzgerald said youngsters needed to move more. Were not talking about trying out for the football team or preparing for the Olympic Games, she wrote. Were talking about walking a mile and touching your toes.

Her only reference to food or beverages was an exhortation for children to eat five or more fruits and vegetables a day.

On Wednesday, CDC spokeswoman Kathy Harben noted in a statement that the Georgia Shape partnership work includes promotion of both physical activity and better nutrition. She continued:At CDC, as at the Georgia Department of Public Health, Dr. Fitzgerald recognizes that public-private partnerships can be powerful tools that help extend public healths reach and ability to save lives, solve problems and speed innovation.

As to whether Georgia's approach, with Coca-Cola's involvement, is one that Fitzgerald might model at the CDC, the statement said: CDC has a focus on scientific integrity and a deep commitment to ethical, innovative partnerships that advance the agencys lifesaving mission.

CDC's website on obesity emphasizes physical activity as well as a healthy diet, including following dietary guidelines to limit eating foods and beverages with added sugars.

Ben Sheidler, a spokesman for Coca-Cola, said the company's position on obesity has shifted in recent years to address sugar consumption specifically. Coke supports the World Health Organization's recommendation that people limit their intake of added sugars to no more than 10 percent of their total daily calorie intake, he said. That's why it now offers smaller-sized drinks and is making more low- and no-sugar drinks available, along with clearer nutritional information, so people can make more informed choices for themselves and their families without the guesswork, he said.

Nationally, there has been growing public concern about beverage companies using philanthropy to fend off public health and regulatory policies that aim to limit soda consumption. CDC itself was criticized in 2016 for two officials' connections to Coca Cola.

Yet some public health groups say industry must be part of the solution. Former first lady Michelle Obamas Lets Move initiative engaged the food and beverage industry as well as public health advocates. The initiative tried to work with food and beverage companies to promote voluntary limits on marketing of lower-value nutrition foods and beverages with limited results, public health analysts said.

A policy expert for a national advocacy group said state health officials often try to find common ground with industry in the fight against obesity, such as emphasizing exercise and promoting healthy eating in general.

Its politically safe to talk about physical activity and eat good stuff. Thats the norm, according to the expert, who spoke on the condition of anonymity because she said she didn't have enough information about Georgia's program. I wouldnt expect many health officers to be out there railing against Coke. Its what youd expect from almost any state health officer from a red state.

More worrisome, others said, are the Trump administrations proposed cuts to CDC. The fiscal 2018 budget would cut CDC by more than $1 billion, with reduced funding for chronic disease prevention and the elimination of funding for several programs. Those include the division of nutrition, obesity and physical activity and the Million Hearts program, an initiative to prevent heart disease, stroke and other cardiovascular diseases.

Alice Crites contributed to this report.

Read more:

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New CDC chief partnered with Coke in state obesity program - Washington Post

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Rowan College at Burlington County in partnership with Virtua, will be offering an associate degree program in Exercise Science Health and Wellness Promotion that will provide a seamless transfer to Rowan University and access to growing field of personal fitness.

As people live longer lives and desire to remain healthy through programs of personal fitness, weve seen a growing demand for athletic trainers and health educators, said Al Campanella, Executive Vice President for Virtua. Students who complete their associate and bachelors degrees in this field will be well prepared for a career in state-of-the-art fitness centers, similar to Virtuas three Health and Wellness centers in southern New Jersey.

This is a great way for students to enter a field that is growing and of interest to many of us who want long, healthy and fulfilling lives, said RCBC Dean of Health Sciences Karen Montalto. Our goal through the Virtua partnership is to ensure our programs are aligned with the healthcare needs of today and tomorrow and this career path certainly meets that objective.

Health Sciences jobs are among the fastest growing in the country. The projected growth between 2014 and 2024 is 21 percent for athletic trainers and 13 percent for health educators. These careers also carry very competitive salaries. Median pay is $44,670 for athletic trainers, $47,010 for exercise physiologists and $43,840 for health educators and community health workers.

Students who take this track can earn their bachelors degree from Rowan University to enter a high-growth, high-pay field, RCBC President Paul Drayton said. This is a great example of the Classroom to Career opportunities RCBC students have because of our partnerships with Rowan University and Virtua.

This program will cover nutritional requirements for consumers that promote health and wellness, explore the relationship of exercise science with health and wellness, and serve as the essential first step for the student who wishes to continue in this field.

Exercise Science is one of four new fall 2017 programs coming to RCBC, a top-ranked and growing community college.

The new programs, which also include Geoscience, Healthcare Informatics and Health Sciences, create affordable pathways into rewarding careers that have a growing demand for new professionals.

For more information and to register go to rcbc.edu/exercise-science

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Rowan College at Burlington County, Virtua announce new career path in exercise, wellness - Burlington County Times

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Losing weight is one thing, Cheri Jackson knows, but keeping it off is another.

Thats why even after losing 113 pounds and being crowned TOPS (Taking Pounds Off Sensibly) 2016 Washington Queen for losing the most weight in the state since she started the program, the Enumclaw resident still plans to stick with the nonprofit program.

Before signing up with TOPS, Jackson had a volatile relationship with food and exercise.

In high school, she suffered from anorexia she didnt eat, and exacerbated her disease by over exercising.

They took me out of school. It was really serious, Jackson said, adding that she weighed 93 pounds.

She wasnt sent anywhere for inpatient treatment, but her mother had her go to the doctors twice a week and have blood tests to make sure everything was going OK.

Jackson eventually brought her eating and exercise habits back under control because she wanted to go back to school.

But when Jackson entered her 30s, she started slipping but in the opposite direction.

Truthfully, in my 30s, I had a hysterectomy and thats when it all went straight down. I started eating I think maybe because I wanted more kids, and I couldnt have more kids, she said.

As Jackson ate more and exercised less, she found herself in constant pain, so she went to her doctor to ask about weight-loss surgery.

You just need to get up and start moving, he told Jackson, who was put off by his answer and delayed any sort of weight-loss action for another five or so years.

It wasnt until she had to receive steroid shots to manage the pain of two herniated disks in her lower back did she finally call up a friend who was already involved with TOPS.

This was it. Either Im going to sit on a couch and be big and heavy and not have a life, or Im going to do something, she said. It was my last ditch effort.

Last ditch or no, Jackson was successful in her weight-loss endeavor, and was flown out to Little Rock, Arkansas on July 11 to celebrate her achievement with other TOPS royalty at the International Recognition Days celebration.

GROUP SUPPORT, PROFESSIONAL INFORMATION

Eating more consciously and exercising more regularly certainly contributed to Jacksons success with TOPS.

But one thing she feels helped her out more than anything else was the support she received from her local TOPS chapter, especially surrounding how she talked negatively about food and her weight.

I used to say horrible things, and theyd say, Are you serious? Yeah, Im serious, Jackson said, adding how shed call herself a cow or a whale. They started supporting me You need to stop. Instead of saying something like that, say something nice about yourself. Find something nice to say about yourself.

According to TOPS Wellness Manager Maggie Thorison, this sort of group support is one of the reasons why this nonprofit works better than other programs.

Sometimes you see or hear the terms good foods and bad foods, or as so many of us have said, I was so bad last night, I had a slice of cake, or, I was really good today, I didnt have many carbs at dinner, Thorison said. While statements like, I was good, or, I was bad, may seem kind of harmless, in a way when youre referring to foods as good or bad, youre saying youre good or bad when you eat those foods.

This is where many meal plans fall short and how group support can pick up the slack, Thorison said. Meal plans can tell you what to eat and how much, but its much harder to be introspective about your eating habits the how and why you eat on your own, instead of in a group setting.

Of course, TOPS doesnt expect every group to be able to do this without some help, and since most local chapters are led by volunteers with little to no nutritional background or wellness expertise, the nonprofit works to provide easily digestible professional information to their members.

Theres a lot of nutrition information out there, whether you see something on TV, maybe something pops up on your Facebook news feed, maybe a friend has this new diet shes been trying. Unfortunately theres a lot of bad or misleading information out there, and it can be really difficult for people to navigate, Thorison said. We provide (chapters) with resources such as programs, which is essentially scripted information geared toward the lay person all of those materials are either created by or reviewed by medical doctors, registered dietitians and other wellness experts.

This sort of flexibility allows individual chapters to determine what their needs are, as opposed to trying to fit their members to a particular meal program or exercise regimen.

We dont tell members what to eat. We dont dictate one specific food plan or try to sell foods. We know that different tools work for different people, Thorison said. Everyone is unique, and of course we want members to be safe before anything else.

That being said, there are still pitfalls people can fall into.

Since TOPS chapters are led by volunteers, there is no screening process for serious eating disorders.

While the information TOPS provides its chapters supports healthy eating and exercising habits, there is little information provided about preventing or treating an eating disorder, Thorison said, adding that all TOPS members are encouraged to check in with a primary physician before making changes to their meal plan or exercise routine, and to check in with them regularly to make sure they are staying healthy.

You can find a local meeting at http://www.tops.org/TOPS/FindAMeeting or by calling 800-932-8677. Membership is $32 a year, plus any chapter fees.

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Enumclaw tops weight-loss royalty celebrates success - Enumclaw Courier-Herald

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All kids should be involved in a fitness or exercise program. Although many kids participate in sports, their practices and games do not guarantee that they are exercising for the recommended 60 minutes a day. According to American College of Sports Medicine, kids should be working out at a moderate to high intensity on a daily basis. To develop a well-rounded young athlete they should be performing the following during their workout sessions:

Most parents and coaches agree that Americas youth needs to participate in more fitness conditioning. Surprisingly, youth strength training is still considered controversial. It is a myth that strength/weight training is unsafe or dangerous for kids. Strength training is another great way to improve your childs overall sports performance, build their confidence and mitigate injuries.

Full length of young woman lifting barbell in gym

For so many decades, it has been believed that children 7 years and older should not partake in traditional strength training programs. However, push-ups, burpees and jump training are a big part of most competitive youth athletic programs. These basic total body exercises will enhance a kids overall fitness level and even develop some strength; but a structured strength training program is far more likely to improve a childs overall muscular development, coordination and fitness level. Despite this widespread myth, there is tremendous research and support from the sports sciences community encouraging parents to enroll their children in some form of a strength and conditioning program. If your kids are dedicated athletes and/or playing their sport for the majority of the year, strength and conditioning classes can have a positive impact on athletic development and help to mitigate injuries.

Myth-busting

It is a myth that strength training will damage a childs growth plates. It was originally thought that the gravitational pressure of weights would lead to damage of the soft growth plates located at the end of the bones. This damage would occur after the bones healed, leading to pre-mature fusing, which in turn would stunt growth. This is not true.

How does a kids body develop strength?

The bodys muscles can not differentiate between resistance that is being applied by a dumbbellor stress applied from aggressive playing, manual labor or sport specific movements like pull-ups, rope climbs, leaping and landing off the monkey bars. A childs body in many ways is more amazing than an adults. While it is growing it is constantly adapting. In fact, the muscles will contract and create force to counter the weight it is experiencing in an effort to enhance strength. It becomes stronger because it is forced to adapt. Consistent and regular strength training will increase the strength of a childs muscles and joints. Other benefits include improving the neuromuscular connection between the body and the brain essentiallyenhancing the neuro-mechanical coordination. The brain and the body communicate by sending signals. The goal is that the signals sent tell the appropriate muscles to fire or contract. When the body experiences structured strength training it recognizes how to recruit and contract these muscles more efficiently and when it is thenneeded to respond to a dynamic or explosive movement (i.e. sports movements).

Pee Wee Conditioning Class

10Guidelines for Youth Strength Training

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10 Guidelines for Youth Strength Training - ChicagoNow (blog)

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BOSTON--(BUSINESS WIRE)--Gelesis, Inc., a biotechnology company developing a novel category of therapies to safely induce weight loss, improve glycemic control, and treat other chronic diseases related to the gastrointestinal (GI) pathway, is pleased to report today that the last patient has completed treatment in the pivotal GLOW (Gelesis Loss Of Weight) Study. The GLOW study was designed to assess the long-term efficacy and safety of lead product candidate Gelesis100 over a six-month period across a broad patient population. The company has also enrolled its first European patient in the ongoing LIGHT-UP study with its second product candidate, Gelesis200, for weight loss and glycemic control. The study will enroll individuals who are overweight or have obesity and also have prediabetes or metformin-treated type 2 diabetes at more than 30 sites across the United States, Canada, and Europe.

Were pleased to have reached these two milestones for Gelesis as we continue to progress our platform technology and expand our pipeline, said Hassan Heshmati MD, Chief Medical Officer of Gelesis. Were also continuing to establish a body of data around our platform technology, as we explore additional GI-related conditions such as nonalcoholic fatty liver disease (NAFLD), nonalcoholic steatohepatitis (NASH), and inflammatory bowel disease (IBD).

Further investigation of the Gelesis mechanism has led to an international collaboration with leading obesity and nutrition experts and new insights about how people with prediabetes respond to different types of diets, published in the American Journal of Clinical Nutrition. We are learning a remarkable amount about the potential positive impact on local inflammation and glycemic parameters through our unique hydrogel system that is at the forefront of mechanobiology, added Elaine Chiquette, Pharm.D., EVP Head of Science, Gelesis. This emerging field at the interface of biology and engineering focuses on how cells sense and respond to mechanical stimuli and is helping us to unlock insights into the gut-brain-inflammation axis.

About Gelesis100 and Gelesis200Gelesis100 is a pivotal-stage product candidate for weight loss and glycemic control, which has demonstrated statistically significant weight loss, reduced hunger, increased satiety and strong safety in previous clinical studies. Gelesis200 is a second product candidate that has been engineered for rapid hydration with significantly higher elasticity to enhance glycemic control and weight loss for patients who have pre-diabetes or type 2 diabetes. A proof-of-concept clinical study with Gelesis200 (LIGHT-UP) has been initiated for weight loss and glycemic control in people with prediabetes or type 2 diabetes. The results from this study are expected mid-2018.

Both Gelesis100 and Gelesis200 are orally administered capsules containing small hydrogel particles made by cross-linking two naturally occurring food ingredients to generate novel compositions that are expected to be safe and well tolerated. Gelesis product candidates are designed to employ multiple mechanisms of action that leverage mechanotransduction along the gastrointestinal (GI) tract to induce weight loss and improve glycemic control. The hydrogel particles swell and shrink in different parts of the GI system, mix homogeneously with food, travel through the GI tract, and once in the large intestines release most of the water, which is reabsorbed by the body. The small hydrogel particles are then safely eliminated by the body in the same manner as food.

To our knowledge, Gelesis novel hydrogels are the only super absorbents made from materials which are considered Generally Recognized As Safe (GRAS) by the U.S. Food and Drug Administration (FDA) and commonly used in foods. Gelesis also received positive confirmation from the FDA that GLOW is a nonsignificant risk (NSR) device study. Gelesis holds 11 families of patents, several of which have already been allowed or issued in major markets. Most recently, Gelesis received a Notice of Allowance from Japan Patent Office (JPO) on Patent No. 2014-514632 covering composition of matter for Gelesis100.

About GelesisGelesis is developing a novel hydrogel platform to treat obesity and other chronic diseases related to the gastrointestinal (GI) pathway. Gelesis proprietary approach acts mechanically in the GI system to potentially alter the course of chronic diseases safely and effectively. Gelesis is currently evaluating its lead product candidate, Gelesis100, in a pivotal trial for weight loss, which is expected to read out in Q3 2017. Additionally, Gelesis recently initiated a proof-of-concept study for its second candidate, Gelesis200, which is optimized for weight loss and glycemic control in patients with type 2 diabetes and pre-diabetes. New hydrogel compositions based on the Gelesis platform are also being explored in preclinical and pilot studies in other GI-related conditions such as nonalcoholic fatty liver disease (NAFLD), nonalcoholic steatohepatitis (NASH), and inflammatory bowel disease (IBD).

The Gelesis executive and advisory team includes some of the worlds leading experts in obesity research and clinical development, innovators in material science, and entrepreneurs. Gelesis was co-founded byPureTech Health (PRTC.L), an advanced, clinical-stage biopharmaceutical company (www.puretechhealth.com).

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Ask an elite athlete how nutrition factors into her performance, and shell likely tell you that its just as important as her training plan. In many cases, she may even call it the most important factor. But the increased effort levels during training can make sticking to your diet tough since even healthy regimens often include eliminating classic performance foodslike lean proteins if youre vegetarianor carbs if youre paleo. If you fall into one of these camps, rest easy. A few small tweaks will give your body what it needs to crank at its full potential. We spoke with two sports dietitians who work with high-performing endurance athletesHeather Mangieri, spokesperson for the Academy of Nutrition and Dietetics, and Barbara Lewin, sports dietitian for the U.S. Olympic Registryfor the details.

Keto dieters get about 75 to 85 percent of their calories from fat and eat very few carbohydrates (generally fewer than 50 grams a day). Although revered by many endurance athletes, the keto approach to healthful eating can backfire if you arent deliberate about finding your fuel elsewhere, getting adequately diverse nutrient intake, and tracking whether your body is adapting to fat burning.

Emphasize Diversity: You need a lot of vitamins, minerals, and natural antioxidants when youre training. Without a careful approach to keto, you risk micronutrient deficiency, Mangieri says. Make sure youre not eating the same rotation of foods. Instead, rely on easy swaps to ensure youre putting a variety of vitamins and minerals into your body without having to take a supplement.

Monitor Your Performance: Its been the silver bullet for many athletes, but the keto program doesnt have the same impact on every individual, so it remains debated. Many people can run a marathon or do a tri while following the keto rules of thumb, but science shows that increasing intensity typically requires carbohydrates, Lewin says. She recommends keeping a journal to monitor what youre eating and how youre performing in your training. Its key to see if youre falling off pace or exerting more effort to clock in at slower times without necessarily noticing it.

Gluten-free athletes avoid foods that most others consider essential to their training. Thankfully, eating gluten-free is a breeze these days with so many healthy choices, Lewin says. But there are still a few pitfalls to watch for.

Skip the Packaged Foods: A diet packed with gluten-free bread, crackers, and pastas isnt inherently healthy or useful for fueling hard training, since those foods often have added sugar or fat to make them more palatable. Instead, eat naturally gluten-free foods like quinoa and starchy vegetables like sweet potatoes or corn, Mangieri says.

Go for Variety: Gluten-free dieters often eat a lot of rice productsrice bread, rice crackers, rice pastaso they get a limited nutritional panel on repeat. Instead, switch up your alternative-carb products so you get a longer list of macros (and prevent stale taste buds). Try bean-based pastas, buckwheat pancake mixes, or corn tortillas instead of flour.

Plant-based diets have become the darlings of the health world and the hallmark of many exemplary endurance athletes, but its surprisingly easy to eat a very unhealthy diet even when cutting out animal products. Its less about what you arent eating and more about what you are eating, Mangieri says. To really perform your best, you need to be a well-rounded vegan or vegetarian. That means your pantry cant be filled solely with energy bars and protein powder.

Pay Attention to Protein: Get your protein from real plants. There is a lot of amino-rich produce out thereyou just have to be a little more conscious of making sure youre getting enough. It may be worth using a food-tracking app at the start to guarantee that youre getting the recommended 90 grams a day. Besides beans and legumeslauded as plant-based protein sourceschia seeds, wild rice, oatmeal, and even potatoes contain significant amounts of plant protein that can be easily incorporated into your meals throughout the day

Be Mindful of B12: Strict vegans need to be sure theyre getting enough vitamin B12, which is naturally found only in meat and is essential for red blood cell production. Try incorporating fortified cereals or alternative milks a few times a day. If youre really struggling to hit the mark, pop a B12 vitamin daily.

Time Your Fiber Wisely: I recommend that triathletes and runners reduce their fiber for two days prior to their race, eating fewer big salads and the like. This may actually reduce their weight by a few pounds and will reduce GI issues and the chance they have to find a restroom along the way, Lewin says. Thats tough for anyone who abstains from meat, but its important for being race-ready.

Athletes who fuel themselves on this ancestral diet eschew agricultural-era foods such as grains, legumes, dairy, and refined foods while focusing on meat, fish, fruits, and veggies. Its pretty easy to be a paleo athlete as long as you time the carbs you do eat for adequate fueling and recovery.

Enjoy Those Well-Timed Potatoes: The Paleo Diet for Athletes allows high-glycemic carbs like potatoes around your training and racing times to ensure you have adequate glycogen stores for high-intensity efforts and recovery.

Make Your Own Sports Drinks: Commercial sports drinks will be off-limits, but you can make your own from raw honey, sea salt, lemon juice, and water.

Some athletes believe this approach helps them stay lean and fast. There is good research that this pattern of eating can be beneficial. You just need to practice it wisely, Lewin says.

Eat Enough: For athletes, the goal of intermittent fasting isnt to go into starvation mode or to shed pounds quickly. Instead, its meant to increase your strength-to-weight ratio by triggering your body to burn fat stores. When you do eat, you want to make sure you consume enough to maintain muscle mass, restock your glycogen store, and stay fueled.

Time It Right: Schedule your high-intensity sessions close to your last meal so you have fuel on board. Avoid prolonged fasts of more than two to three days just before races so you dont go in with depleted glycogen stores.

Raw-food practitioners, notably professional triathlete Brendan Brazier, fill themselves with foods that havent been cooked, believing that modern cooking deleteriously alters foods nutritional content. The foods you choose and how you prepare them can have a major impact on how well (or not) you do as you train.

Prioritize Protein: Its easy to feel satisfied on uncooked foods yet miss out on getting the protein you need. Raw, less-processed food fills your stomach faster even if it doesnt give you lasting energy. To combat this effect, eat a large variety of nuts, seeds, legumes, and vegetables, rather than just munching on raw crudits and trail mix, to get all your essential amino acids without filling up first.

Think About Fiber: Fiber hits harder with a raw-food diet because your body has to do all the work of digesting it without the help of cooking, which might ordinarily kick-start the breakdown process. A high fiber pre-workout or pre-race meal doesnt sit very well and usually doesnt provide adequate calories, Lewin says. The same is true for recovery. Eating a high-fiber recovery meal means that you miss the window of 20 to 30 minutes after your workout where the body is able to most efficiently restore muscle glycogen levels and rebuild muscle. Juicing some of your foods will help eliminate some of the fiber while still providing nutrition.

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How to Ramp Up Training and Stay HealthyNo Matter Your Diet - Outside Magazine

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If you've ever Googled "how to lose weight fast'" you're not alone. Whether it's for an impending wedding or event, or you've noticed some weight gain (thanks winter), many of us are looking for ways to look slimmer quickly.

So, can you lose weight fast (and safely)?

"It really depends on how much weight you have to lose and the time frame in which you do it," nutritionist Fiona Tuck told HuffPost Australia.

"If it's a kilo or two then this can be lost relatively quickly. However, losing a huge amount of weight in a short amount of time can put excess strain and stress on the body, cause muscle loss, put the body into starvation mode and can put a strain on the heart, and is not a healthy way to lose weight."

Basically, you can lose weight quickly, but it's not the best option and doesn't beat steady long-term weight loss.

"Studies show it is more effective to aim for gradual weight loss as opposed to rapid weight loss," accredited practising dietitian Anna Debenham said. "This is because you are more likely to lose weight and keep it off when it's lost gradually. In addition to this, it is healthier for your body to lose weight more slowly."

As accredited practising dietitian Alexandra Parker explained, focusing on short-term weight loss doesn't change our eating habits and lifestyle for the better.

"Generally we find that people who want quick fixes are not necessarily in the right frame of mind to lose weight," Parker told HuffPost Australia. "So much of healthy eating and weight loss is about having the right mind frame and changing your eating behaviours for the long term.

PeopleImages via Getty Images Focus on a healthy lifestyle, rather than a fad diet.

"Successful weight management comes down to a lifelong commitment to a healthy lifestyle, which combines eating healthy foods, forming a healthy relationship with food and keeping physically active."

Particularly when it comes to reaching body composition goals, personal trainer and founder of Flow Athletic Ben Lucas highlights that we can't expect to see changes in a few days or a week.

"I often see clients who come in and say they want to work on their arms or legs for an event or occasion, and believe toned, sculpted arms can be achieved in a few short sessions," Lucas said.

"When it comes to making physical changes in our body, this can take weeks of dedication. So, in terms of fitness, it doesn't happen overnight."

With all this in mind, if you do want to lose weight fast, here's how to do it relatively safely. Remember, seek advise from a healthcare professional before starting any diet.

Getty

"Many people can lose weight rapidly simply by cutting out refined carbohydrates such as white pasta, white rice and sugar," Tuck said.

Other refined carb foods include lollies, biscuits, pastries and chips.

"High carbohydrate foods can encourage the body to store fluid, hence the puffy face when people overindulge in junk food and alcohol."

Here are handy tips on how to avoid buying junk food at the supermarket.

Controlling your portion sizes can help you lose weight, although Parker and Debenham recommend doing this under healthcare supervision to avoid under-eating.

"Tightening up portion sizes and cutting down on certain foods can work in the short-term, but not forever," Parker said.

"The key to safe weight loss is not to cut out any food groups completely, but rather reduce overall portion sizes. There is a fine line here as cutting down too much on these foods can hinder your ability to meet your nutritional requirements," Debenham said.

Try these eight doable portion control tips.

Merinka via Getty Images

"Choose lean protein and veggies and salads, and limit saturated fats," Tuck said.

While reducing carb intake can be effective, Tuck urges people to not follow this style of eating for long.

"Long-term eating in this way, such as cutting out whole grains and high carbohydrate foods, is not recommended as it can put the body at risk of nutritional deficiencies," Tuck said. "Including carbs is important for brain function and energy, however choosing whole grain, nutrient-rich options is the healthier choice."

Here's a whole library of delicious, healthy meals.

"In addition to dietary changes, I would have them working on strength which includes cardio, such as boxing," Lucas told HuffPost Australia.

"Boxing activates multiple muscle groups as well as gets the heart rate up. The idea behind this is that you start burning the calories with the aerobic demands of boxing, but also work on resistance training using your arms, which continue to burn energy after.

"Additionally, you help to tone, especially in the abdominal region, thanks to the demands of a strong core for twisting, ducking and punching."

Cecilie_Arcurs via Getty Images Exercise is as good for the body as it is for the mind.

Alcoholic drinks -- whether they're marketed as 'low carb' or not -- are packed with empty calories, meaning that cutting down or ditching alcohol altogether can have a dramatic effect on weight.

"Eating lean and clean with a diet made up mostly of vegetables, protein and a little bit of fat can help shed kilos quickly," Lucas said. "Ditching refined carbohydrates, sugar and alcohol will also make a noticeable difference. Staying hydrated also helps to prevent fluid retention."

When trying to lose weight quickly, health experts suggest to steer clear of doing these things.

"Avoid dramatic long-term calorie reduction. This can cause dizziness, affect blood sugar and can even lower metabolism and deplete nutrients if performed over a long period of time," Tuck said.

"Avoid fad diets that remove food groups for more than a couple of weeks, or which recommend an excess of a particular food group, as this can become nutritionally imbalanced."

The same goes for skipping meals, which does more harm than good.

"A common danger is skipping meals, which is unsafe. If you continuously skip meals, your body thinks it is being starved and may hold on to fat reserves rather than shed them," Lucas said.

"Depriving yourself could also end up in a binge. Instead, reduce your portion sizes rather than eliminating a whole meal."

Dzevoniia via Getty Images Skip the juice cleanse and focus on whole foods instead.

Parker also warns against going on detoxes (they don't work) or taking pills or supplements that promise rapid weight loss. When it comes to long-term weight loss and weight maintenance, slow and steady wins the race.

"There is no magic pill or miracle cure. Cutting down on portion size, including a variety of fresh whole foods daily and eating three meals a day (with light snacks if required) is the most sustainable long-term fix to weight loss," Tuck said.

"Healthy eating needs to become a way of life. And including daily exercise is important for energy, mood, metabolism, self-esteem and heart health."

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